{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:13:04Z","timestamp":1767705184944},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T00:00:00Z","timestamp":1241481600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic diseases affect millions of children worldwide leading to substantial disease burden to the children and their families as well as escalating health care costs. The increasing trend in the prevalence of complex pediatric chronic diseases requires innovative and optimal delivery of care. Biomedical informatics applications play an important role in improving health outcomes while being cost-effective. However, their utility in pediatric chronic diseases has not been studied in a comprehensive and systematic way. The objective of this study was to conduct a systematic review of the effects of biomedical informatics applications in pediatric chronic diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive literature search was conducted using MEDLINE, the Cochrane Library and EMBASE databases from inception of each database to September 2008. We included studies of any methodological type and any language that applied biomedical informatics to chronic conditions in children and adolescents 18 years of age or younger. Two independent reviewers carried out study selection and data extraction. Quality assessment was performed using a study design evaluation instrument to appraise the strength of the studies and their methodological adequacy. Because of heterogeneity in the conditions and outcomes we studied, a formal meta-analysis was not performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on our search strategy, 655 titles and abstracts were reviewed. From this set we identified 27 relevant articles that met our inclusion criteria. The results from these studies indicated that biomedical informatics applications have favourable clinical and patient outcomes including, but not limited to, reduced number of emergency room visits, improved knowledge on disease management, and enhanced satisfaction. Seventy percent of reviewed papers were published after year 2000, 89% of users were patients and 11% were either providers or caregivers. The majority (96%) of the selected studies reported improved outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Published studies suggested positive impacts of informatics predominantly in pediatric asthma. As electronic tools become more widely adopted, there will be opportunities to improve patient care in a wide range of chronic illnesses through informatics solutions.<\/jats:p><\/jats:sec>","DOI":"10.1186\/1472-6947-9-22","type":"journal-article","created":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T18:16:33Z","timestamp":1241547393000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Application of biomedical informatics to chronic pediatric diseases: a systematic review"],"prefix":"10.1186","volume":"9","author":[{"given":"Fatemeh","family":"Moeinedin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahim","family":"Moineddin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro R","family":"Jadad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jemila S","family":"Hamid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"To","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Beyene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,5,5]]},"reference":[{"key":"264_CR1","volume-title":"Chronic Disease Fact Sheet","author":"World Health Organization","year":"2005","unstructured":"World Health Organization: Chronic Disease Fact Sheet. 2005, [http:\/\/www.who.int\/chp\/chronic_disease_report\/contents\/part1.pdf]"},{"key":"264_CR2","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1197\/jamia.M2255","volume":"14","author":"D Dorr","year":"2007","unstructured":"Dorr D, Bonner LM, Cohen AN, Shoai RS, Perrin R, Chaney E, Young AS: Informatics systems to promote improved care for chronic illness: a literature review. J Am Med Inform Assoc. 2007, 14: 156-163. 10.1197\/jamia.M2255.","journal-title":"J Am Med Inform Assoc"},{"key":"264_CR3","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1001\/archinte.162.20.2269","volume":"162","author":"JL Wolff","year":"2002","unstructured":"Wolff JL, Starfield B, Anderson G: Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Arch Intern Med. 2002, 162: 2269-2276. 10.1001\/archinte.162.20.2269.","journal-title":"Arch Intern Med"},{"key":"264_CR4","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1001\/jama.297.24.2755","volume":"297","author":"JM Perrin","year":"2007","unstructured":"Perrin JM, Bloom SR, Gortmaker SL: The increase of childhood chronic conditions in the United States. JAMA. 2007, 297: 2755-2759. 10.1001\/jama.297.24.2755.","journal-title":"JAMA"},{"key":"264_CR5","unstructured":"Haydon Emma, Roerecke Michael, Giesbrecht Norman, Rehm J\u00fcrgen, Kobus-Matthews Marianne: Chronic Disease in Ontario and Canada: Determinants, Risk Factors and Prevention Priorities. [http:\/\/www.ocdpa.on.ca\/docs\/CDP-SummaryReport-Mar06.pdf]"},{"key":"264_CR6","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1136\/jech.56.11.808","volume":"56","author":"JC Wyatt","year":"2002","unstructured":"Wyatt JC, Liu JLY: Basic concepts in medical informatics. (Glossary). Journal of Epidemiology & Community Health. 2002, 56: 808-813. 10.1136\/jech.56.11.808.","journal-title":"Journal of Epidemiology & Community Health"},{"key":"264_CR7","volume-title":"Center for Biomedical Informatics: Introductory Lecture Series","author":"C Friedman","year":"1996","unstructured":"Friedman C: Medical Informatics: Challenges and Opportunities. Center for Biomedical Informatics: Introductory Lecture Series. 1996"},{"key":"264_CR8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1197\/jamia.M2270","volume":"14","author":"G Pare","year":"2007","unstructured":"Pare G, Jaana M, Sicotte C: Systematic review of home telemonitoring for chronic diseases: the evidence base. J Am Med Inform Assoc. 2007, 14: 269-277. 10.1197\/jamia.M2270.","journal-title":"J Am Med Inform Assoc"},{"key":"264_CR9","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1197\/jamia.M2039","volume":"13","author":"DL Sanders","year":"2006","unstructured":"Sanders DL, Aronsky D: Biomedical informatics applications for asthma care: a systematic review. J Am Med Inform Assoc. 2006, 13: 418-427. 10.1197\/jamia.M2039.","journal-title":"J Am Med Inform Assoc"},{"key":"264_CR10","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1001\/jama.280.15.1339","volume":"280","author":"DL Hunt","year":"1998","unstructured":"Hunt DL, Haynes RB, Hanna SE, Smith K: Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. JAMA. 1998, 280: 1339-1346. 10.1001\/jama.280.15.1339.","journal-title":"JAMA"},{"key":"264_CR11","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1093\/ajhp\/60.19.1976","volume":"60","author":"DS Chan","year":"2003","unstructured":"Chan DS, Callahan CW, Sheets SJ, Moreno CN, Malone FJ: An Internet-based store-and-forward video home telehealth system for improving asthma outcomes in children. American Journal of Health-System Pharmacy. 2003, 60: 1976-1981.","journal-title":"American Journal of Health-System Pharmacy"},{"key":"264_CR12","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1136\/jamia.2001.0080049","volume":"8","author":"R Shegog","year":"2001","unstructured":"Shegog R, Bartholomew LK, Parcel GS, Sockrider MM, Masse L, Abramson SL: Impact of a computer-assisted education program on factors related to asthma self-management behavior. Journal of the American Medical Informatics Association. 2001, 8: 49-56.","journal-title":"Journal of the American Medical Informatics Association"},{"key":"264_CR13","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0738-3991(99)00045-2","volume":"39","author":"LK Bartholomew","year":"2000","unstructured":"Bartholomew LK, Shegog R, Parcel GS, Gold RS, Fernandez M, Czyzewski DI, Sockrider MM, Berlin N: Watch, Discover, Think, and Act: a model for patient education program development. Patient Education & Counseling. 2000, 39: 253-268. 10.1016\/S0738-3991(99)00045-2.","journal-title":"Patient Education & Counseling"},{"key":"264_CR14","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/S0891-5245(02)88328-6","volume":"17","author":"K Huss","year":"2003","unstructured":"Huss K, Winkelstein M, Nanda J, Naumann PL, Sloand ED, Huss RW: Computer game for inner-city children does not improve asthma outcomes. Journal of Pediatric Health Care. 2003, 17: 72-78.","journal-title":"Journal of Pediatric Health Care"},{"key":"264_CR15","doi-asserted-by":"publisher","first-page":"32","DOI":"10.7748\/paed2002.03.14.2.32.c787","volume":"14","author":"A McPherson","year":"2002","unstructured":"McPherson A, Forster D, Glazebrook C, Smyth A: The asthma files: evaluation of a multimedia package for children's asthma education. Paediatric Nursing. 2002, 14: 32-35.","journal-title":"Paediatric Nursing"},{"key":"264_CR16","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1197\/jamia.M1569","volume":"11","author":"SC Porter","year":"2004","unstructured":"Porter SC, Cai Z, Gribbons W, Goldmann DA, Kohane IS: The asthma kiosk: a patient-centered technology for collaborative decision support in the emergency department. Journal of the American Medical Informatics Association. 2004, 11: 458-567. 10.1197\/jamia.M1569.","journal-title":"Journal of the American Medical Informatics Association"},{"key":"264_CR17","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1542\/peds.111.3.503","volume":"111","author":"S Krishna","year":"2003","unstructured":"Krishna S, Francisco BD, Balas EA, Konig P, Graff GR, Madsen RW: Internet-enabled interactive multimedia asthma education program: a randomized trial. Pediatrics. 2003, 111: 503-510. 10.1542\/peds.111.3.503.","journal-title":"Pediatrics"},{"key":"264_CR18","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1542\/peds.106.S1.210","volume":"106","author":"C Homer","year":"2000","unstructured":"Homer C, Susskind O, Alpert HR, Owusu M, Schneider L, Rappaport LA, Rubin DH: An evaluation of an innovative multimedia educational software program for asthma management: report of a randomized, controlled trial. Pediatrics. 2000, 106: 210-215.","journal-title":"Pediatrics"},{"key":"264_CR19","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1097\/00004583-200502000-00010","volume":"44","author":"T Klingberg","year":"2005","unstructured":"Klingberg T, Fernell E, Olesen PJ, Johnson M, Gustafsson P, Dahlstrom K, Gillberg CG, Forssberg H, Westerberg H: Computerized training of working memory in children with ADHD \u2013 a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry. 2005, 44: 177-186. 10.1097\/00004583-200502000-00010.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"264_CR20","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1177\/002221949502800105","volume":"28","author":"JW Van Strien","year":"1995","unstructured":"Van Strien JW, Stolk BD, Zuiker S: Hemisphere-specific treatment of dyslexia subtypes: better reading with anxiety-laden words?. J Learn Disabil. 1995, 28: 30-34. 10.1177\/002221949502800105.","journal-title":"J Learn Disabil"},{"key":"264_CR21","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/0270-4684(85)90004-7","volume":"5","author":"AJ Plienis","year":"1985","unstructured":"Plienis AJ, Romanczyk RG: Analyses of performance, behavior, and predictors for severely disturbed children: a comparison of adult vs. computer instruction. nalysis and intervention in developmental disabilites. 1985, 5: 345-356. 10.1016\/0270-4684(85)90004-7.","journal-title":"nalysis and intervention in developmental disabilites"},{"key":"264_CR22","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1177\/002221949202500306","volume":"25","author":"D Van","year":"1992","unstructured":"Van D, Leij van der A: Computer-based reading and spelling practice for children with learning disabilities. J Learn Disabil. 1992, 25: 186-195. 10.1177\/002221949202500306.","journal-title":"J Learn Disabil"},{"key":"264_CR23","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1177\/002221948902200205","volume":"22","author":"SV Horton","year":"1989","unstructured":"Horton SV, Lovitt TC, Givens A, Nelson R: Teaching Social Studies to High School Students with Academic Handicaps in a Mainstreamed Setting: effects of a computerized study guide. J Learn Disabil. 1989, 22: 102-107. 10.1177\/002221948902200205.","journal-title":"J Learn Disabil"},{"key":"264_CR24","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1177\/002221948902200907","volume":"22","author":"LS Fuchs","year":"1989","unstructured":"Fuchs LS, Bahr CM, Rieth HJ: Effects of goal structures and performance contingencies on the math performance of adolescents with learning disabilities. J Learn Disabil. 1989, 22: 554-560. 10.1177\/002221948902200907.","journal-title":"J Learn Disabil"},{"key":"264_CR25","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1177\/002221949002300902","volume":"23","author":"K Higgins","year":"1990","unstructured":"Higgins K, Boone R: Hypertext Computer Study Guides and the Social Studies Achievement of Students with Learning Disabilities, Remedial Students, and Regular Education Students. J Learn Disabil. 1990, 23: 529-540. 10.1177\/002221949002300902.","journal-title":"J Learn Disabil"},{"key":"264_CR26","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1177\/1362361399003002004","volume":"3","author":"V Bernard-Opitz","year":"1999","unstructured":"Bernard-Opitz V, Sriram N, Sapuan S: Enhancing Vocal Limitations in Children with Autism Using the IBM SpeechViewer. Autism. 1999, 3: 131-147. 10.1177\/1362361399003002004.","journal-title":"Autism"},{"key":"264_CR27","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1177\/1362361302006001006","volume":"6","author":"C Williams","year":"2002","unstructured":"Williams C, Wright B, Callaghan G, Coughlan B: Do children with autism learn to read more readily by computer assisted instruction or traditional book methods? A pilot study. Autism: the international journal of research and practice. 2002, 6: 71-91.","journal-title":"Autism: the international journal of research and practice"},{"key":"264_CR28","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1023\/A:1010660502130","volume":"31","author":"V Bernard-Opitz","year":"2001","unstructured":"Bernard-Opitz V, Sriram N, Nakhoda-Sapuan S: Enhancing social problem solving in children with autism and normal children through computer-assisted instruction. J Autism Dev Disord. 2001, 31: 377-384. 10.1023\/A:1010660502130.","journal-title":"J Autism Dev Disord"},{"key":"264_CR29","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1469-7610.1996.tb01387.x","volume":"37","author":"J Swettenham","year":"1996","unstructured":"Swettenham J: Can children with autism be taught to understand false belief using computers?. J Child Psychol Psychiatry. 1996, 37: 157-165. 10.1111\/j.1469-7610.1996.tb01387.x.","journal-title":"J Child Psychol Psychiatry"},{"key":"264_CR30","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1023\/A:1005535602064","volume":"30","author":"M Moore","year":"2000","unstructured":"Moore M, Calvert S: Brief report: vocabulary acquisition for children with autism: teacher or computer instruction. J Autism Dev Disord. 2000, 30: 359-362. 10.1023\/A:1005535602064.","journal-title":"J Autism Dev Disord"},{"key":"264_CR31","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.brainres.2007.10.108","volume":"1205","author":"C Stevens","year":"2008","unstructured":"Stevens C, Fanning J, Coch D, Sanders L, Neville H: Neural mechanisms of selective auditory attention are enhanced by computerized training: Electrophysiological evidence from language-impaired and typically developing children. Brain Research. 2008, 1205: 55-69. 10.1016\/j.brainres.2007.10.108.","journal-title":"Brain Research"},{"issue":"Suppl 1","key":"264_CR32","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.33588\/rn.46S01.2007662","volume":"46","author":"A Miranda-Casas","year":"2008","unstructured":"Miranda-Casas A, Marco-Taverner R, Soriano-Ferrer M, Meli\u00e0 de Alba A, Sim\u00f3-Casa\u00f1 P: [The application of new technologies to solving maths problems for students with learning disabilities: the 'underwater school']. Revista de neurologia. 2008, 46 (Suppl 1): S59-S63.","journal-title":"Revista de neurologia"},{"key":"264_CR33","first-page":"355","volume":"25","author":"M Kast","year":"2007","unstructured":"Kast M, Meyer M, Vogeli C, Gross M, Jancke L: Computer-based multisensory learning in children with developmental dyslexia. Restor Neurol Neurosci. 2007, 25: 355-369.","journal-title":"Restor Neurol Neurosci"},{"key":"264_CR34","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1080\/09297040600770787","volume":"13","author":"L Shalev","year":"2007","unstructured":"Shalev L, Tsal Y, Mevorach C: Computerized progressive attentional training (CPAT) program: Effective direct intervention for children with ADHD. Child Neuropsychology. 2007, 13: 382-388. 10.1080\/09297040600770787.","journal-title":"Child Neuropsychology"},{"key":"264_CR35","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1001\/archpedi.160.5.495","volume":"160","author":"GR Kim","year":"2006","unstructured":"Kim GR, Chen AR, Arceci RJ, Mitchell SH, Kokoszka KM, Daniel D, Lehmann CU: Error reduction in pediatric chemotherapy: computerized order entry and failure modes and effects analysis. Arch Pediatr Adolesc Med. 2006, 160: 495-498. 10.1001\/archpedi.160.5.495.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"264_CR36","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1111\/j.1365-2141.2005.05541.x","volume":"129","author":"J Bury","year":"2005","unstructured":"Bury J, Hurt C, Roy A, Cheesman L, Bradburn M, Cross S, Fox J, Saha V: LISA: a web-based decision-support system for trial management of childhood acute lymphoblastic leukaemia. Br J Haematol. 2005, 129: 746-754. 10.1111\/j.1365-2141.2005.05541.x.","journal-title":"Br J Haematol"},{"key":"264_CR37","first-page":"21","volume":"22","author":"M Petersen","year":"1996","unstructured":"Petersen M: What are blood counts? A computer-assisted program for pediatric patients. Pediatr Nurs. 1996, 22: 21-25.","journal-title":"Pediatr Nurs"},{"key":"264_CR38","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/0169-2607(90)90112-M","volume":"32","author":"G Zahlmann","year":"1990","unstructured":"Zahlmann G, Franczykova M, Henning G, Strube M, Huttl I, Hummel I, Bruns W: DIABETEX \u2013 a decision support system for therapy of type I diabetic patients. Computer Methods & Programs in Biomedicine. 1990, 32: 297-301. 10.1016\/0169-2607(90)90112-M.","journal-title":"Computer Methods & Programs in Biomedicine"},{"key":"264_CR39","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1177\/014572179001600311","volume":"16","author":"PP Horan","year":"1990","unstructured":"Horan PP, Yarborough MC, Besigel G, Carlson DR: Computer-assisted self-control of diabetes by adolescents. Diabetes Educator. 1990, 16: 205-211. 10.1177\/014572179001600311.","journal-title":"Diabetes Educator"},{"key":"264_CR40","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1471-2431-7-4","volume":"7","author":"WJ King","year":"2007","unstructured":"King WJ, Le Saux N, Sampson M, Gaboury I, Norris M, Moher D: Effect of point of care information on inpatient management of bronchiolitis. BMC Pediatr. 2007, 7: 4-10.1186\/1471-2431-7-4.","journal-title":"BMC Pediatr"},{"key":"264_CR41","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.pain.2003.10.005","volume":"107","author":"TM Palermo","year":"2004","unstructured":"Palermo TM, Valenzuela D, Stork PP: A randomized trial of electronic versus paper pain diaries in children: impact on compliance, accuracy, and acceptability. Pain. 2004, 107: 213-219. 10.1016\/j.pain.2003.10.005.","journal-title":"Pain"},{"key":"264_CR42","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1037\/0090-5550.50.4.337","volume":"50","author":"SL Wade","year":"2005","unstructured":"Wade SL, Wolfe CR, Pestian JP, Brown T: Can a Web-Based Family Problem-Solving Intervention Work for Children with Traumatic Brain Injury?. Rehabilitation Psychology. 2005, 50: 337-345. 10.1037\/0090-5550.50.4.337.","journal-title":"Rehabilitation Psychology"},{"key":"264_CR43","doi-asserted-by":"publisher","first-page":"742","DOI":"10.7326\/0003-4819-144-10-200605160-00125","volume":"144","author":"B Chaudhry","year":"2006","unstructured":"Chaudhry B, Wang J, Wu S, Maglione M, Mojica W, Roth E, Morton SC, Shekelle PG: Systematic Review: Impact of Health Information Technology on Quality, Efficiency, and Costs of Medical Care. Ann Intern Med. 2006, 144: 742-752.","journal-title":"Ann Intern Med"},{"key":"264_CR44","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5694\/j.1326-5377.2003.tb05529.x","volume":"179","author":"BG Celler","year":"2003","unstructured":"Celler BG, Lovell NH, Basilakis J: Using information technology to improve the management of chronic disease. Medical Journal of Australia. 2003, 179: 242-246.","journal-title":"Medical Journal of Australia"},{"key":"264_CR45","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.apnr.2004.04.003","volume":"18","author":"M Frenn","year":"2005","unstructured":"Frenn M, Malin S, Brown RL, Greer Y, Fox J, Greer J, Smyczek S: Changing the tide: an Internet\/video exercise and low-fat diet intervention with middle-school students. Applied Nursing Research. 2005, 18: 13-21. 10.1016\/j.apnr.2004.04.003.","journal-title":"Applied Nursing Research"}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-9-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1472-6947-9-22\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-9-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1472-6947-9-22.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T01:22:10Z","timestamp":1684977730000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/1472-6947-9-22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,5]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["264"],"URL":"https:\/\/doi.org\/10.1186\/1472-6947-9-22","relation":{},"ISSN":["1472-6947"],"issn-type":[{"value":"1472-6947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,5]]},"assertion":[{"value":"18 December 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"22"}}