{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:25:28Z","timestamp":1771482328723,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microb Cell Fact"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1475-2859-13-80","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T13:02:42Z","timestamp":1401886962000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Improved delivery of the OVA-CD4 peptide to T helper cells by polymeric surface display on Salmonella"],"prefix":"10.1186","volume":"13","author":[{"given":"Junjie","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon","family":"De Masi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beena","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter M","family":"Schifferli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"989_CR1","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1146\/annurev-biochem-061408-144611","volume":"80","author":"CL Hagan","year":"2011","unstructured":"Hagan CL, Silhavy TJ, Kahne D: beta-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem. 2011, 80: 189-210. 10.1146\/annurev-biochem-061408-144611.","journal-title":"Annu Rev Biochem"},{"key":"989_CR2","doi-asserted-by":"publisher","first-page":"4250","DOI":"10.1128\/JB.00192-11","volume":"193","author":"AE Rossiter","year":"2011","unstructured":"Rossiter AE, Leyton DL, Tveen-Jensen K, Browning DF, Sevastsyanovich Y, Knowles TJ, Nichols KB, Cunningham AF, Overduin M, Schembri MA, Henderson IR: The essential beta-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis. J Bacteriol. 2011, 193: 4250-4253. 10.1128\/JB.00192-11.","journal-title":"J Bacteriol"},{"key":"989_CR3","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.resmic.2013.03.010","volume":"164","author":"J Grijpstra","year":"2013","unstructured":"Grijpstra J, Arenas J, Rutten L, Tommassen J: Autotransporter secretion: varying on a theme. Res Microbiol. 2013, 164: 562-582. 10.1016\/j.resmic.2013.03.010.","journal-title":"Res Microbiol"},{"key":"989_CR4","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.copbio.2010.07.009","volume":"21","author":"WS Jong","year":"2010","unstructured":"Jong WS, Sauri A, Luirink J: Extracellular production of recombinant proteins using bacterial autotransporters. Curr Opin Biotechnol. 2010, 21: 646-652. 10.1016\/j.copbio.2010.07.009.","journal-title":"Curr Opin Biotechnol"},{"key":"989_CR5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.tibtech.2010.11.003","volume":"29","author":"E van Bloois","year":"2011","unstructured":"van Bloois E, Winter RT, Kolmar H, Fraaije MW: Decorating microbes: surface display of proteins on Escherichia coli. Trends Biotechnol. 2011, 29: 79-86. 10.1016\/j.tibtech.2010.11.003.","journal-title":"Trends Biotechnol"},{"key":"989_CR6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/j.1365-2958.2005.04666.x","volume":"57","author":"CW Dorsey","year":"2005","unstructured":"Dorsey CW, Laarakker MC, Humphries AD, Weening EH, Baumler AJ: Salmonella enterica serotype Typhimurium MisL is an intestinal colonization factor that binds fibronectin. Mol Microbiol. 2005, 57: 196-211. 10.1111\/j.1365-2958.2005.04666.x.","journal-title":"Mol Microbiol"},{"key":"989_CR7","doi-asserted-by":"publisher","first-page":"3611","DOI":"10.1128\/IAI.70.7.3611-3620.2002","volume":"70","author":"F Ruiz-Perez","year":"2002","unstructured":"Ruiz-Perez F, Leon-Kempis R, Santiago-Machuca A, Ortega-Pierres G, Barry E, Levine M, Gonzalez-Bonilla C: Expression of the Plasmodium falciparum immunodominant epitope (NANP)(4) on the surface of Salmonella enterica using the autotransporter MisL. Infect Immun. 2002, 70: 3611-3620. 10.1128\/IAI.70.7.3611-3620.2002.","journal-title":"Infect Immun"},{"key":"989_CR8","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/S0147-619X(03)00047-7","volume":"50","author":"P Ruiz-Olvera","year":"2003","unstructured":"Ruiz-Olvera P, Ruiz-Perez F, Sepulveda NV, Santiago-Machuca A, Maldonado-Rodriguez R, Garcia-Elorriaga G, Gonzalez-Bonilla C: Display and release of the Plasmodium falciparum circumsporozoite protein using the autotransporter MisL of Salmonella enterica. Plasmid. 2003, 50: 12-27. 10.1016\/S0147-619X(03)00047-7.","journal-title":"Plasmid"},{"key":"989_CR9","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.vetpar.2013.01.056","volume":"194","author":"AM Alvarez","year":"2013","unstructured":"Alvarez AM, Vaquero-Vera A, Fonseca-Linan R, Ruiz-Perez F, Villegas-Sepulveda N, Ortega-Pierres G: A prime-boost vaccination of mice with attenuated Salmonella expressing a 30-mer peptide from the Trichinella spiralis gp43 antigen. Vet Parasitol. 2013, 194: 202-206. 10.1016\/j.vetpar.2013.01.056.","journal-title":"Vet Parasitol"},{"key":"989_CR10","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1016\/j.vaccine.2006.11.006","volume":"25","author":"H Chen","year":"2007","unstructured":"Chen H, Schifferli DM: Comparison of a fimbrial versus an autotransporter display system for viral epitopes on an attenuated Salmonella vaccine vector. Vaccine. 2007, 25: 1626-1633. 10.1016\/j.vaccine.2006.11.006.","journal-title":"Vaccine"},{"key":"989_CR11","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1038\/mi.2011.2","volume":"4","author":"AJ Griffin","year":"2011","unstructured":"Griffin AJ, McSorley SJ: Development of protective immunity to Salmonella, a mucosal pathogen with a systemic agenda. Mucosal Immunol. 2011, 4: 371-382. 10.1038\/mi.2011.2.","journal-title":"Mucosal Immunol"},{"key":"989_CR12","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1146\/annurev.immunol.19.1.23","volume":"19","author":"MK Jenkins","year":"2001","unstructured":"Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA: In vivo activation of antigen-specific CD4 T cells. Annu Rev Immunol. 2001, 19: 23-45. 10.1146\/annurev.immunol.19.1.23.","journal-title":"Annu Rev Immunol"},{"key":"989_CR13","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.2217\/fmb.10.97","volume":"5","author":"B John","year":"2010","unstructured":"John B, Weninger W, Hunter CA: Advances in imaging the innate and adaptive immune response to Toxoplasma gondii. Future Microbiol. 2010, 5: 1321-1328. 10.2217\/fmb.10.97.","journal-title":"Future Microbiol"},{"key":"989_CR14","doi-asserted-by":"publisher","first-page":"7240","DOI":"10.1128\/IAI.72.12.7240-7246.2004","volume":"72","author":"M Pepper","year":"2004","unstructured":"Pepper M, Dzierszinski F, Crawford A, Hunter CA, Roos D: Development of a system to study CD4\u2009+\u2009-T-cell responses to transgenic ovalbumin-expressing Toxoplasma gondii during toxoplasmosis. Infect Immun. 2004, 72: 7240-7246. 10.1128\/IAI.72.12.7240-7246.2004.","journal-title":"Infect Immun"},{"key":"989_CR15","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/j.1600-065X.1997.tb00959.x","volume":"156","author":"KA Pape","year":"1997","unstructured":"Pape KA, Kearney ER, Khoruts A, Mondino A, Merica R, Chen ZM, Ingulli E, White J, Johnson JG, Jenkins MK: Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo. Immunol Rev. 1997, 156: 67-78. 10.1111\/j.1600-065X.1997.tb00959.x.","journal-title":"Immunol Rev"},{"key":"989_CR16","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1128\/IAI.67.4.2025-2029.1999","volume":"67","author":"ZM Chen","year":"1999","unstructured":"Chen ZM, Jenkins MK: Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Itys) and resistant (Ityr) BALB\/c mice. Infect Immun. 1999, 67: 2025-2029.","journal-title":"Infect Immun"},{"key":"989_CR17","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1111\/j.1365-2567.2005.02140.x","volume":"114","author":"R Ravindran","year":"2005","unstructured":"Ravindran R, McSorley SJ: Tracking the dynamics of T-cell activation in response to Salmonella infection. Immunology. 2005, 114: 450-458. 10.1111\/j.1365-2567.2005.02140.x.","journal-title":"Immunology"},{"key":"989_CR18","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S0928-8244(03)00064-6","volume":"37","author":"D Bumann","year":"2003","unstructured":"Bumann D: T cell receptor-transgenic mouse models for studying cellular immune responses to Salmonella in vivo. FEMS Immunol Med Microbiol. 2003, 37: 105-109. 10.1016\/S0928-8244(03)00064-6.","journal-title":"FEMS Immunol Med Microbiol"},{"key":"989_CR19","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/0264-410X(95)00216-N","volume":"14","author":"LP Londono","year":"1996","unstructured":"Londono LP, Chatfield S, Tindle RW, Herd K, Gao XM, Frazer I, Dougan G: Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine. 1996, 14: 545-552. 10.1016\/0264-410X(95)00216-N.","journal-title":"Vaccine"},{"key":"989_CR20","doi-asserted-by":"publisher","first-page":"3129","DOI":"10.1128\/IAI.68.6.3129-3139.2000","volume":"68","author":"H Chen","year":"2000","unstructured":"Chen H, Schifferli DM: Mucosal and systemic immune responses to chimeric fimbriae expressed by Salmonella enterica Serovar Typhimurium vaccine strains. Infect Immun. 2000, 68: 3129-3139. 10.1128\/IAI.68.6.3129-3139.2000.","journal-title":"Infect Immun"},{"key":"989_CR21","doi-asserted-by":"publisher","first-page":"2889","DOI":"10.1093\/nar\/19.11.2889","volume":"19","author":"MD Oxer","year":"1991","unstructured":"Oxer MD, Bentley CM, Doyle JG, Peakman TC, Charles IG, Makoff AJ: High level heterologous expression in E. coli using the anaerobically-activated nirB promoter. Nucleic Acids Res. 1991, 19: 2889-2892. 10.1093\/nar\/19.11.2889.","journal-title":"Nucleic Acids Res"},{"key":"989_CR22","volume-title":"Vaccine","author":"JE Galen","year":"2013","unstructured":"Galen JE, Curtiss R: The delicate balance in genetically engineering live vaccines. Vaccine. 2013, published on line December 23, 2013; http:\/\/dx.doi.org\/10.1016\/j.vaccine.2013.12.026"},{"key":"989_CR23","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1128\/IAI.00916-09","volume":"78","author":"JE Galen","year":"2010","unstructured":"Galen JE, Wang JY, Chinchilla M, Vindurampulle C, Vogel JE, Levy H, Blackwelder WC, Pasetti MF, Levine MM: A new generation of stable, nonantibiotic, low-copy-number plasmids improves immune responses to foreign antigens in Salmonella enterica serovar Typhi live vectors. Infect Immun. 2010, 78: 337-347. 10.1128\/IAI.00916-09.","journal-title":"Infect Immun"},{"key":"989_CR24","doi-asserted-by":"publisher","first-page":"4664","DOI":"10.1128\/IAI.71.8.4664-4673.2003","volume":"71","author":"H Chen","year":"2003","unstructured":"Chen H, Schifferli DM: Construction, characterization and immunogenicity of an attenuated Salmonella enterica Serovar Typhimurium pgtE vaccine expressing fimbriae with integrated viral epitopes from the spiC promoter. Infect Immun. 2003, 71: 4664-4673. 10.1128\/IAI.71.8.4664-4673.2003.","journal-title":"Infect Immun"},{"key":"989_CR25","doi-asserted-by":"publisher","first-page":"2790","DOI":"10.1002\/eji.1830261135","volume":"26","author":"MJ Wick","year":"1996","unstructured":"Wick MJ, Pfeifer JD: Major histocompatibility complex class I presentation of ovalbumin peptide 257\u2013264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996, 26: 2790-2799. 10.1002\/eji.1830261135.","journal-title":"Eur J Immunol"},{"key":"989_CR26","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1365-2567.2007.02561.x","volume":"121","author":"LJ Carreno","year":"2007","unstructured":"Carreno LJ, Bueno SM, Bull P, Nathenson SG, Kalergis AM: The half-life of the T-cell receptor\/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology. 2007, 121: 227-237. 10.1111\/j.1365-2567.2007.02561.x.","journal-title":"Immunology"},{"key":"989_CR27","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1046\/j.1365-2958.1999.01272.x","volume":"31","author":"DE Higgins","year":"1999","unstructured":"Higgins DE, Shastri N, Portnoy DA: Delivery of protein to the cytosol of macrophages using Escherichia coli K-12. Mol Microbiol. 1999, 31: 1631-1641. 10.1046\/j.1365-2958.1999.01272.x.","journal-title":"Mol Microbiol"},{"key":"989_CR28","doi-asserted-by":"publisher","first-page":"3402","DOI":"10.4049\/jimmunol.166.5.3402","volume":"166","author":"C Pope","year":"2001","unstructured":"Pope C, Kim SK, Marzo A, Masopust D, Williams K, Jiang J, Shen H, Lefrancois L: Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection. J Immunol. 2001, 166: 3402-3409. 10.4049\/jimmunol.166.5.3402.","journal-title":"J Immunol"},{"key":"989_CR29","doi-asserted-by":"publisher","first-page":"3558","DOI":"10.1016\/j.molimm.2008.05.010","volume":"45","author":"K Serre","year":"2008","unstructured":"Serre K, Mohr E, Toellner KM, Cunningham AF, Granjeaud S, Bird R, MacLennan IC: Molecular differences between the divergent responses of ovalbumin-specific CD4 T cells to alum-precipitated ovalbumin compared to ovalbumin expressed by Salmonella. Mol Immunol. 2008, 45: 3558-3566. 10.1016\/j.molimm.2008.05.010.","journal-title":"Mol Immunol"},{"key":"989_CR30","doi-asserted-by":"publisher","first-page":"e1002966","DOI":"10.1371\/journal.ppat.1002966","volume":"8","author":"S Barat","year":"2012","unstructured":"Barat S, Willer Y, Rizos K, Claudi B, Maze A, Schemmer AK, Kirchhoff D, Schmidt A, Burton N, Bumann D: Immunity to intracellular Salmonella depends on surface-associated antigens. PLoS Pathog. 2012, 8: e1002966-10.1371\/journal.ppat.1002966.","journal-title":"PLoS Pathog"},{"key":"989_CR31","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/0882-4010(87)90022-2","volume":"2","author":"DJ Maskell","year":"1987","unstructured":"Maskell DJ, Sweeney KJ, O'Callaghan D, Hormaeche CE, Liew FY, Dougan G: Salmonella typhimurium aroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systems. Microb Pathog. 1987, 2: 211-221. 10.1016\/0882-4010(87)90022-2.","journal-title":"Microb Pathog"},{"key":"989_CR32","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/0882-4010(88)90002-2","volume":"5","author":"D Hone","year":"1988","unstructured":"Hone D, Attridge S, van den Bosch L, Hackett J: A chromosomal integration system for stabilization of heterologous gene in Salmonella based vaccine strains. Microb Pathog. 1988, 5: 407-418. 10.1016\/0882-4010(88)90002-2.","journal-title":"Microb Pathog"},{"key":"989_CR33","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0378-1119(91)90492-T","volume":"108","author":"BJ Froehlich","year":"1991","unstructured":"Froehlich BJ, Scott JR: A single-copy promoter-cloning vector for use in Escherichia coli. Gene. 1991, 108: 99-101. 10.1016\/0378-1119(91)90492-T.","journal-title":"Gene"},{"key":"989_CR34","doi-asserted-by":"publisher","first-page":"3243","DOI":"10.1016\/j.vaccine.2004.05.014","volume":"22","author":"ND McKelvie","year":"2004","unstructured":"McKelvie ND, Stratford R, Wu T, Bellaby T, Aldred E, Hughes NJ, Chatfield SN, Pickard D, Hale C, Dougan G, Khan SA: Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG. Vaccine. 2004, 22: 3243-3255. 10.1016\/j.vaccine.2004.05.014.","journal-title":"Vaccine"},{"key":"989_CR35","doi-asserted-by":"publisher","first-page":"4828","DOI":"10.1128\/IAI.00298-10","volume":"78","author":"X Xu","year":"2010","unstructured":"Xu X, Husseiny MI, Goldwich A, Hensel M: Efficacy of intracellular activated promoters for generation of Salmonella-based vaccines. Infect Immun. 2010, 78: 4828-4838. 10.1128\/IAI.00298-10.","journal-title":"Infect Immun"},{"key":"989_CR36","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1128\/CVI.00253-08","volume":"16","author":"M Saxena","year":"2009","unstructured":"Saxena M, Coloe PJ, Smooker PM: Influence of promoter, gene copy number, and preexisting immunity on humoral and cellular responses to a vectored antigen delivered by a Salmonella enterica vaccine. Clin Vaccine Immunol. 2009, 16: 78-87. 10.1128\/CVI.00253-08.","journal-title":"Clin Vaccine Immunol"},{"key":"989_CR37","doi-asserted-by":"publisher","first-page":"7493","DOI":"10.1128\/IAI.69.12.7493-7500.2001","volume":"69","author":"D Bumann","year":"2001","unstructured":"Bumann D: Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responses. Infect Immun. 2001, 69: 7493-7500. 10.1128\/IAI.69.12.7493-7500.2001.","journal-title":"Infect Immun"},{"key":"989_CR38","doi-asserted-by":"publisher","first-page":"5071","DOI":"10.1016\/j.vaccine.2007.03.047","volume":"25","author":"R Luria-Perez","year":"2007","unstructured":"Luria-Perez R, Cedillo-Barron L, Santos-Argumedo L, Ortiz-Navarrete VF, Ocana-Mondragon A, Gonzalez-Bonilla CR: A fusogenic peptide expressed on the surface of Salmonella enterica elicits CTL responses to a dengue virus epitope. Vaccine. 2007, 25: 5071-5085. 10.1016\/j.vaccine.2007.03.047.","journal-title":"Vaccine"},{"key":"989_CR39","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1128\/MMBR.00011-07","volume":"71","author":"J Jose","year":"2007","unstructured":"Jose J, Meyer TF: The autodisplay story, from discovery to biotechnical and biomedical applications. Microbiol Mol Biol Rev. 2007, 71: 600-619. 10.1128\/MMBR.00011-07.","journal-title":"Microbiol Mol Biol Rev"},{"key":"989_CR40","doi-asserted-by":"publisher","first-page":"3946","DOI":"10.1128\/IAI.00112-06","volume":"74","author":"DI Loeffler","year":"2006","unstructured":"Loeffler DI, Schoen CU, Goebel W, Pilgrim S: Comparison of different live vaccine strategies in vivo for delivery of protein antigen or antigen-encoding DNA and mRNA by virulence-attenuated Listeria monocytogenes. Infect Immun. 2006, 74: 3946-3957. 10.1128\/IAI.00112-06.","journal-title":"Infect Immun"},{"key":"989_CR41","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1128\/IAI.06056-11","volume":"80","author":"WA Hegazy","year":"2012","unstructured":"Hegazy WA, Xu X, Metelitsa L, Hensel M: Evaluation of Salmonella enterica type III secretion system effector proteins as carriers for heterologous vaccine antigens. Infect Immun. 2012, 80: 1193-1202. 10.1128\/IAI.06056-11.","journal-title":"Infect Immun"},{"key":"989_CR42","first-page":"109","volume-title":"DNA cloning: a practical approach","author":"D Hanahan","year":"1985","unstructured":"Hanahan D: Techniques for transformation of E. coli. DNA cloning: a practical approach. Edited by: Glover DM. 1985, Oxford, UK: IRL Press, 1: 109-135."},{"key":"989_CR43","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/0378-1119(85)90120-9","volume":"33","author":"C Yanisch-Perron","year":"1985","unstructured":"Yanisch-Perron C, Vieira J, Messing J: Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene. 1985, 33: 103-119. 10.1016\/0378-1119(85)90120-9.","journal-title":"Gene"},{"key":"989_CR44","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1038\/291238a0","volume":"291","author":"SK Hoiseth","year":"1981","unstructured":"Hoiseth SK, Stocker BD: Aromatic-dependent Salmonella typhimurium are nonvirulent and effective as live vaccines. Nature. 1981, 291: 238-239. 10.1038\/291238a0.","journal-title":"Nature"},{"key":"989_CR45","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1128\/iai.62.5.1669-1676.1994","volume":"62","author":"F Sch\u00f6del","year":"1994","unstructured":"Sch\u00f6del F, Kelly SM, Peterson DL, Milich DR, Curtiss R: Hybrid hepatitis B virus core-pre-S proteins synthesized in avirulent Salmonella typhimurium and Salmonella typhi for oral vaccination. Infect Immun. 1994, 62: 1669-1676.","journal-title":"Infect Immun"},{"key":"989_CR46","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1128\/jb.176.4.1099-1110.1994","volume":"176","author":"DM Schifferli","year":"1994","unstructured":"Schifferli DM, Alrutz M: Permissive linker insertion sites in the outer membrane protein of 987P fimbriae of Escherichia coli. J Bacteriol. 1994, 176: 1099-1110.","journal-title":"J Bacteriol"},{"key":"989_CR47","doi-asserted-by":"publisher","first-page":"4837","DOI":"10.1073\/pnas.76.10.4837","volume":"76","author":"M Achtman","year":"1979","unstructured":"Achtman M, Manning PA, Edelbluth C, Herrlich P: Export without proteolytic processing of inner and outer membrane proteins encoded by F sex factor Tra cistrons in Escherichia coli minicells. Proc Natl Acad Sci USA. 1979, 76: 4837-4841. 10.1073\/pnas.76.10.4837.","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Microbial Cell Factories"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1475-2859-13-80.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T09:26:58Z","timestamp":1630574818000},"score":1,"resource":{"primary":{"URL":"https:\/\/microbialcellfactories.biomedcentral.com\/articles\/10.1186\/1475-2859-13-80"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,4]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["989"],"URL":"https:\/\/doi.org\/10.1186\/1475-2859-13-80","relation":{},"ISSN":["1475-2859"],"issn-type":[{"value":"1475-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,4]]},"assertion":[{"value":"29 September 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"80"}}