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Manifestations among the 139 patients included hypotension (38, 27.3%), cerebral malaria (23, 16.5%), repeated convulsions (18, 13.0%), hypoglycaemia (15, 10.8%), hyperparasitaemia (14, 10.1%), jaundice (14, 10.1%), severe anaemia (10, 7.2%), bleeding (six, 4.3%), renal impairment (one, 0.7%) and more than one criteria (27, 19.4%). While the geometric mean of the parasite count was significantly higher in patients with severe <jats:italic>P. vivax<\/jats:italic> than with severe <jats:italic>P. falciparum<\/jats:italic> malaria (5,934.2 <jats:italic>vs<\/jats:italic> 13,906.6 asexual stage parasitaemia per \u03bcL, p\u2009=\u20090.013), the different disease manifestations were not significantly different between patients with <jats:italic>P. falciparum<\/jats:italic> or <jats:italic>P. vivax<\/jats:italic> malaria. Three patients (2.2%) died due to severe <jats:italic>P. falciparum<\/jats:italic> malaria. One had cerebral malaria, the second had renal impairment, jaundice and hypoglycaemia, and the third had repeated convulsions and hypotension.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Severe malaria due to <jats:italic>P. falciparum<\/jats:italic> and <jats:italic>P. vivax<\/jats:italic> malaria is an existing entity among adults in eastern Sudan. Patients with severe <jats:italic>P. falciparum<\/jats:italic> and <jats:italic>P. vivax<\/jats:italic> develop similar disease manifestations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1475-2875-12-148","type":"journal-article","created":{"date-parts":[[2013,5,2]],"date-time":"2013-05-02T07:18:03Z","timestamp":1367479083000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Severe Plasmodium falciparum and Plasmodium vivax malaria among adults at Kassala Hospital, eastern Sudan"],"prefix":"10.1186","volume":"12","author":[{"given":"Tajeldin M","family":"Abdallah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed T","family":"Abdeen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikhlas S","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamdan Z","family":"Hamdan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoun","family":"Magzoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ishag","family":"Adam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,1]]},"reference":[{"key":"2763_CR1","volume-title":"World Malaria Report 2010","author":"WHO","year":"2010","unstructured":"WHO: World Malaria Report 2010. 2010, Geneva: World Health Organization"},{"key":"2763_CR2","first-page":"S1","volume":"94","author":"WHO\/Communicable diseases cluster","year":"2000","unstructured":"WHO\/Communicable diseases cluster: Severe falciparum malaria. 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