{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:15:35Z","timestamp":1781237735357,"version":"3.54.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Malar J"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Falciparum malaria increases the risk for bacteraemia, whereas the relationship between vivax malaria and bacteraemia is not clear. Data from a prospective fever surveillance study in Kolkata, India were reanalysed for the potential association between <jats:italic>Plasmodium vivax<\/jats:italic> malaria and bacteraemia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients of all ages presenting with fever of three days or more to a project health outpost were invited to participate. A blood film and blood culture was performed on presentation. Treatment and referral were provided according to national guidelines. The case fraction and incidence of malaria, bacteraemia, and co-infection were calculated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>3,371 participants were enrolled during a one-year study period, of whom 93\/3,371 (2.8%) had malaria (89\/93 [95.7%] <jats:italic>Plasmodium vivax<\/jats:italic>) and 256 (7.6%) bacteraemia. There were 154 malaria, 423 bacteraemia and 10 <jats:italic>P. vivax<\/jats:italic>-bacteremia coinfection episodes per 100,000\/year. Among the malaria-bacteraemia co-infections, all were vivax malaria and 5\/6 (83%) bacteria isolated were Gram-negative (one <jats:italic>S.<\/jats:italic> Typhi, one <jats:italic>S.<\/jats:italic> Paratyphi A, three other Gram-negative). Bacteraemia occurred in 6\/89 (6.7% [95%CI: 3.1-13.9%]) of <jats:italic>P. vivax<\/jats:italic> cases versus 250\/3,278 (7.6% [95% CI: 6.7-8.6%]) without <jats:italic>Plasmodium<\/jats:italic> infection (p=0.76).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>While an increased risk was not demonstrated, concomitant bacteraemia occurs frequently in vivax malaria in an area with a high background incidence of bacteraemia, and should be considered in cases of vivax malaria with severe manifestations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1475-2875-12-176","type":"journal-article","created":{"date-parts":[[2013,5,31]],"date-time":"2013-05-31T03:22:34Z","timestamp":1369970554000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Vivax malaria and bacteraemia: a prospective study in Kolkata, India"],"prefix":"10.1186","volume":"12","author":[{"given":"Sujit Kumar","family":"Bhattacharya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipika","family":"Sur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanta","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suman","family":"Kanungo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R Leon","family":"Ochiai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deok Ryun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas M","family":"Anstey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenz","family":"von Seidlein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Deen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,31]]},"reference":[{"key":"2816_CR1","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1016\/S0140-6736(11)61146-X","volume":"378","author":"S Obaro","year":"2011","unstructured":"Obaro S, Greenwood B: Malaria and bacteraemia in African children. 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