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However, PCR amplification of small subunit ribosomal RNA gene revealed a <jats:italic>P. knowlesi<\/jats:italic> infection. Parasitaemia was 473 parasites\/\u03bcl and the platelet count was within the normal range. Oral treatment with Malarone\u00ae was initiated and resulted in a fast recovery without any complications.<\/jats:p>\n          <jats:p>As part of routine screening the patient also underwent HIV testing and was found to be HIV positive with a CD4 cell count of 115\/\u03bcl and a viral load of 34,799 copies\/ml. A follow-up measurement of the viral load seven days after the first quantification revealed an increase to 102,000 copies\/ml. Three months after the first quantification the viral load had dropped to 10,000 copies\/ml without the initiation of antiretroviral treatment. This suggests the possibility of a <jats:italic>P. knowlesi<\/jats:italic> malaria-induced temporary elevation of viral load similar to that reported for <jats:italic>P<\/jats:italic>. <jats:italic>falciparum<\/jats:italic> and HIV co-infection.<\/jats:p>","DOI":"10.1186\/1475-2875-12-283","type":"journal-article","created":{"date-parts":[[2013,8,13]],"date-time":"2013-08-13T12:15:00Z","timestamp":1376396100000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Plasmodium knowlesi and HIV co-infection in a German traveller to Thailand"],"prefix":"10.1186","volume":"12","author":[{"given":"Jonas","family":"Ehrhardt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Trein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Gottfried","family":"Kremsner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Frank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,13]]},"reference":[{"key":"2899_CR1","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/S0140-6736(04)15836-4","volume":"363","author":"B Singh","year":"2004","unstructured":"Singh B, Kim Sung L, Matusop A, Radhakrishnan A, Shamsul SS, Cox-Singh J, Thomas A, Conway DJ, Singh B, Kim Sung L, Matusop A, Radhakrishnan A, Shamsul SS, Cox-Singh J, Thomas A, Conway DJ: A large focus of naturally acquired Plasmodium knowlesi infections in human beings. 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