{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T04:23:52Z","timestamp":1728447832062},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,7,30]],"date-time":"2006-07-30T00:00:00Z","timestamp":1154217600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"},{"start":{"date-parts":[[2006,7,30]],"date-time":"2006-07-30T00:00:00Z","timestamp":1154217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Filaria J"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clinical manifestations of lymphatic filariasis depend on the area of lymphatic involvement and the duration of infection. A 21 year old man, resident in a filariasis endemic region, presented with multiple matted lymph nodes with cystic areas forming a large mass in his left axilla. An ultrasound scan of the axilla using a 7.5 MHz transducer revealed grossly dilated lymphatics but no filarial dance sign. Fine needle (21 G) aspiration cytology (FNAC) from the dilated lymphatics and solid areas in the lymph node mass revealed multiple microfilariae in a background of reactive lymphoid cells. Peripheral blood smears revealed microfilaremia with significant eosinophilia. Diagnosis of left axillary <jats:italic>Bancroftian lymphadenovarix<\/jats:italic> was made. On the administration of oral diethylcarbamazine, the diameter of the lymphatic vessels in the lymphadenovarix reduced considerably in size and microfilaremia disappeared. We report this case because axillary lymphadenovarix is a rare presentation of filariasis. This case is also unique since microfilariae were demonstrated in the fluid aspirated from the dilated lymphatics of the lymphadenovarix in the absence of live adult worms.<\/jats:p>","DOI":"10.1186\/1475-2883-5-9","type":"journal-article","created":{"date-parts":[[2006,8,2]],"date-time":"2006-08-02T08:29:54Z","timestamp":1154507394000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lymphadenovarix in the axilla \u2013 an unusual presentation of filariasis"],"prefix":"10.1186","volume":"5","author":[{"given":"Adhish","family":"Basu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarath Chandra","family":"Sistla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surendra Kumar","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Jagdish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,7,30]]},"reference":[{"key":"57_CR1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0035-9203(02)90288-9","volume":"96","author":"G Dreyer","year":"2002","unstructured":"Dreyer G, Addiss D, Roberts J, Noroes J: Progression of lymphatic vessel dilatation in the presence of living adult Wuchereriabancrofti. Trans R Soc Trop Med Hyg. 2002, 96: 157-161. 10.1016\/S0035-9203(02)90288-9.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"57_CR2","first-page":"1738","volume":"57","author":"SB Sen","year":"1969","unstructured":"Sen SB, Chatterjee H, Ramaprasad S: Chylous manifestations of filariasis: A clinical and lymphographic study. Part II. Lymphadenovarix, chylocele and chylous scrotum. Ind Jour Med Res. 1969, 57: 1738-1744.","journal-title":"Ind Jour Med Res"},{"key":"57_CR3","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1046\/j.1365-3156.1999.00440.x","volume":"4","author":"G Dreyer","year":"1999","unstructured":"Dreyer G, Santos A, Noroes J, Addiss D: Proposed panel of diagnostic criteria, including the use of ultrasound, to refine the concept of 'endemic normals' in lymphatic filariasis. Tropical Medicine and International Health. 1999, 4: 575-579. 10.1046\/j.1365-3156.1999.00440.x.","journal-title":"Tropical Medicine and International Health"},{"key":"57_CR4","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0035-9203(96)90478-2","volume":"90","author":"J Noroes","year":"1996","unstructured":"Noroes J, Addiss D, Amaral F, Coutinho A, Medeiros Z, Dreyer G: Occurrence of adult Wuchereria bancrofti in the scrotal area of men with microfilaremia. Trans R Soc Trop Med Hyg. 1996, 90: 55-56. 10.1016\/S0035-9203(96)90478-2.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"57_CR5","doi-asserted-by":"crossref","first-page":"765","DOI":"10.7863\/jum.2003.22.8.765","volume":"22","author":"NG Chaubal","year":"2003","unstructured":"Chaubal NG, Pradhan GM, Chaubal JN, Ramani SK: Dance of live adult Filarial worms is a reliable sign of scrotal Filarial infection. J Ultrasound Med. 2003, 22: 765-769.","journal-title":"J Ultrasound Med"},{"key":"57_CR6","doi-asserted-by":"crossref","first-page":"325","DOI":"10.4269\/ajtmh.1991.45.325","volume":"45","author":"P Jungmann","year":"1991","unstructured":"Jungmann P, Figueredo-Silva J, Dreyer G: Bancroftian lymphadenopathy: a histopathologic study of fifty-eight cases from northeastern Brazil. Am J Trop Med Hyg. 1991, 45: 325-31.","journal-title":"Am J Trop Med Hyg"},{"key":"57_CR7","first-page":"745","volume":"37","author":"P Dey","year":"1993","unstructured":"Dey P, Radhika S, Jain A: Microfilariae of Wuchereria bancrofti in a lymph node aspirate. A case report. Acta Cytol. 1993, 37: 745-746.","journal-title":"Acta Cytol"},{"key":"57_CR8","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1159\/000333934","volume":"40","author":"K Kapila","year":"1996","unstructured":"Kapila K, Verma K: Diagnosis of parasites in fine needle breast aspirates. Acta Cytol. 1996, 40: 653-656.","journal-title":"Acta Cytol"},{"key":"57_CR9","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1159\/000333755","volume":"40","author":"TR Varghese","year":"1996","unstructured":"Varghese TR, Raghuveer CV, Pai MR, Bansal R: Microfilariae in Cytologic Smears. A Report of Six Cases. Acta Cytol. 1996, 40: 299-301.","journal-title":"Acta Cytol"},{"key":"57_CR10","first-page":"432","volume":"4","author":"A Walter","year":"1983","unstructured":"Walter A, Hemalatha K, Cariappa A: Microfilariae of Wuchereria bancrofti in cytologic smears. Acta Cytol. 1983, 4: 432-436.","journal-title":"Acta Cytol"},{"key":"57_CR11","first-page":"195","volume":"17","author":"GS Reddy","year":"2004","unstructured":"Reddy GS, Das LK, Pani SP: The preferential site of adult Wuchereria bancrofti: an ultrasound study of male asymptomatic microfilaria carriers in Pondicherry, India. Natl Med J India. 2004, 17: 195-196.","journal-title":"Natl Med J India"}],"container-title":["Filaria Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1475-2883-5-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/1475-2883-5-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1475-2883-5-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T10:23:53Z","timestamp":1728383033000},"score":1,"resource":{"primary":{"URL":"https:\/\/filariajournal.biomedcentral.com\/articles\/10.1186\/1475-2883-5-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,30]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2006,12]]}},"alternative-id":["57"],"URL":"https:\/\/doi.org\/10.1186\/1475-2883-5-9","relation":{},"ISSN":["1475-2883"],"issn-type":[{"type":"electronic","value":"1475-2883"}],"subject":[],"published":{"date-parts":[[2006,7,30]]},"assertion":[{"value":"17 October 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2006","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2006","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"9"}}