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The study of the biological activities of these plants is of great importance for the detection of biologically active compounds.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Extracts from these plants were extracted with hexane (Hex), dichloromethane (DCM), ethyl acetate (EtOAc) and ethanol (EtOH) and assessed for their antimicrobial properties, bioactivity against <jats:italic>Artemia salina<\/jats:italic> Leach and antifungal action on the cell wall of <jats:italic>Neurospora crassa<\/jats:italic>.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Extracts from <jats:italic>C. ambrosioides<\/jats:italic> (Hex, DCM and EtOH) and <jats:italic>K. neglecta<\/jats:italic> (EtOAc and EtOH) showed high bioactivity against <jats:italic>A. salina<\/jats:italic> (LD50\u2009&lt;\u20091000 \u03bcg\/mL), which might be associated with cytotoxic activity against cancer cells. <jats:italic>C. ambrosioides<\/jats:italic> Hex and DCM showed specific activity against yeasts, highlighting the activity of hexanic extract against <jats:italic>Candida krusei<\/jats:italic> (MIC\u2009=\u2009100 \u03bcg\/mL). By comparing the inhibitory concentration of 50% growth (IC 50%) with the growth control, extracts from <jats:italic>K. neglecta<\/jats:italic> EtOAc and EtOH have shown activities against multidrug-resistant bacteria (<jats:italic>Enterococcus faecalis<\/jats:italic> ATCC 51299 and <jats:italic>Staphylococcus aureus<\/jats:italic> ATCC 43300), with IC 50% of 12.5 \u03bcg\/mL The assay carried out on <jats:italic>N. crassa<\/jats:italic> allowed defining that extracts with antifungal activity do not have action through inhibition of cell wall synthesis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Generally speaking, extracts from <jats:italic>C. ambrosioides<\/jats:italic> and <jats:italic>K. neglecta<\/jats:italic> showed biological activities that have made the search for bioactive substances in these plants more attractive, illustrating the success of their use in the Brazilian folk medicine.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1476-0711-11-20","type":"journal-article","created":{"date-parts":[[2012,7,28]],"date-time":"2012-07-28T14:14:22Z","timestamp":1343484862000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Biological activities of extracts from Chenopodium ambrosioides Lineu and Kielmeyera neglecta Saddi"],"prefix":"10.1186","volume":"11","author":[{"given":"Zulane Lima","family":"Sousa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Faustino","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Oliveira","family":"da Concei\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Alberto Mattos","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Helena","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianada Silva","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Luciano","family":"Andrioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,7,28]]},"reference":[{"key":"263_CR1","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.phymed.2003.11.004","volume":"12","author":"R Fenner","year":"2005","unstructured":"Fenner R, Sortino M, Kuze Rates SM, Dall\u2019Agnol R, Ferraz A, Bernardi AP, Albring D, N\u00f6r C, von Poser G, Schapoval E, Zacchino S: Antifungal activity of some Brazilian Hypericum species. 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