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An overlap may exist between nutrients that potentially have both anti-acne and mood regulating properties; examples include omega-3 fatty acids from fish oil, chromium, zinc and selenium. Here we report on five cases of acne treated with eicosapentaenoic acid and antioxidant nutrients. Self-administration of these nutrients may have improved inflammatory acne lesions and global aspects of well-being; the observations suggest a need for controlled trials.<\/jats:p>","DOI":"10.1186\/1476-511x-7-36","type":"journal-article","created":{"date-parts":[[2008,10,14]],"date-time":"2008-10-14T06:13:58Z","timestamp":1223964838000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Acne vulgaris, mental health and omega-3 fatty acids: a report of cases"],"prefix":"10.1186","volume":"7","author":[{"given":"Mark G","family":"Rubin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan C","family":"Logan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,10,13]]},"reference":[{"key":"174_CR1","first-page":"85","volume":"68","author":"NB Silverberg","year":"2001","unstructured":"Silverberg NB, Weinberg JM: Rosacea and adult acne: a worldwide epidemic. 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