{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:56:20Z","timestamp":1787237780279,"version":"build-2736575974"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lipids Health Dis"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The supply of long-chain polyunsaturated fatty acids via the placenta is interrupted in premature infants, making them exclusively dependent on breast milk, which varies in fatty acid (FA) concentrations depending on the mother's diet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To in a longitudinal study explore the relation between FA status in mothers and infants from an unselected cohort of prematures, not requiring intensive care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Breast milk and mothers' and infants' plasma phospholipid FA concentrations from birth to 44 weeks of gestational age were analysed and compared with mothers' food intake, assessed using a 3-day diary. Fatty acids were analysed by capillary gas-liquid chromatography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The energy intake was low in 75% of mothers, and 90% had low intake of essential FAs (EFAs). Dietary linoleic acid (LA, 18:2w6), but not w3 FAs, correlated to concentrations in breast milk. Infants' plasma and breast milk correlated for arachidonic (AA, 20:4w6), eicosapentaenoic (EPA, 20:5w3) and docosahexaenoic (DHA, 22:6w3) acids. A high concentration of mead acid (20:3w9) in the infants at birth correlated negatively to the concentrations of LA, AA and w3 FAs. Infants of mothers who stopped breastfeeding during the study period showed decreased DHA concentrations and increased w6\/w3 ratios, with the opposite FA pattern seen in the mothers' plasma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although dietary w3 FAs were insufficient in an unselected cohort of mothers of premature infants, breastfeeding resulted in increased levels of DHA in the premature infants at the expense of the mothers, suggesting a general need to increase dietary w3 FAs during pregnancy and lactation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/1476-511x-8-20","type":"journal-article","created":{"date-parts":[[2009,6,10]],"date-time":"2009-06-10T14:13:59Z","timestamp":1244643239000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Fatty acid patterns early after premature birth, simultaneously analysed in mothers' food, breast milk and serum phospholipids of mothers and infants"],"prefix":"10.1186","volume":"8","author":[{"given":"Karl-G\u00f6ran","family":"Sabel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Lundqvist-Persson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Bona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Petzold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitta","family":"Strandvik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,6,10]]},"reference":[{"key":"208_CR1","volume-title":"Growth and composition of the fetus and newborn","year":"1968","unstructured":"Widdowson EM, : Growth and composition of the fetus and newborn. Edited by: Assali NS. 1968, Academic Press, New York, NY,"},{"key":"208_CR2","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/S0140-6736(76)91476-8","volume":"1","author":"MA Crawford","year":"1976","unstructured":"Crawford MA, Hassam AG, Williams G: Essential fatty acids and fetal brain growth. Lancet. 1976, 1: 452-3. 10.1016\/S0140-6736(76)91476-8","journal-title":"Lancet"},{"key":"208_CR3","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0378-3782(80)90015-8","volume":"4","author":"MT Clandinin","year":"1980","unstructured":"Clandinin MT, Chappell JE, Leong S, Heim T, Swyer PR, Chance GW: Intrauterine fatty acid accretion rates in human brain: implications for fatty acid requirements. Early Hum Dev. 1980, 4: 121-9. 10.1016\/0378-3782(80)90015-8","journal-title":"Early Hum Dev"},{"key":"208_CR4","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0163-7827(91)90006-Q","volume":"30","author":"SM Innis","year":"1991","unstructured":"Innis SM: Essential fatty acids in growth and development. Prog Lipid Res. 1991, 30: 39-103. 10.1016\/0163-7827(91)90006-Q","journal-title":"Prog Lipid Res"},{"key":"208_CR5","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1079\/BJN19950106","volume":"74","author":"MD Al","year":"1995","unstructured":"Al MD, van Houwelingen AC, Kester AD, Hasaart TH, de Jong AE, Hornstra G: Maternal essential fatty acid patterns during normal pregnancy and their relationship to the neonatal essential fatty acid status. Br J Nutr. 1995, 74: 55-68. 10.1079\/BJN19950106","journal-title":"Br J Nutr"},{"issue":"Suppl A","key":"208_CR6","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1053\/plac.2002.0771","volume":"23","author":"E Herrera","year":"2002","unstructured":"Herrera E: Implications of dietary fatty acids during pregnancy on placental, fetal and postnatal development \u2013 a review. Placenta. 2002, 23 (Suppl A): S9-19. 10.1053\/plac.2002.0771","journal-title":"Placenta"},{"key":"208_CR7","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1194\/jlr.M500415-JLR200","volume":"47","author":"A Joardar","year":"2006","unstructured":"Joardar A, Sen AK, Das S: Docosahexaenoic acid facilitates cell maturation and beta-adrenergic transmission in astrocytes. J Lipid Res. 2006, 47: 571-81. 10.1194\/jlr.M500415-JLR200","journal-title":"J Lipid Res"},{"key":"208_CR8","doi-asserted-by":"publisher","first-page":"3084","DOI":"10.1111\/j.1460-9568.2006.05185.x","volume":"24","author":"G Champeil-Potokar","year":"2006","unstructured":"Champeil-Potokar G, Chaumontet C, Guesnet P, Lavialle M, Denis I: Docosahexaenoic acid (22:6n-3) enrichment of membrane phospholipids increases gap junction coupling capacity in cultured astrocytes. Eur J Neurosci. 2006, 24: 3084-90. 10.1111\/j.1460-9568.2006.05185.x","journal-title":"Eur J Neurosci"},{"key":"208_CR9","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1093\/ajcn\/58.5.653","volume":"58","author":"JC Martin","year":"1993","unstructured":"Martin JC, Bougnoux P, Fignon A, Theret V, Antoine JM, Lamisse F, Couet C: Dependence of human milk essential fatty acids on adipose stores during lactation. Am J Clin Nutr. 1993, 58: 653-9.","journal-title":"Am J Clin Nutr"},{"issue":"Suppl A","key":"208_CR10","doi-asserted-by":"publisher","first-page":"S28","DOI":"10.1053\/plac.2002.0791","volume":"23","author":"P Haggarty","year":"2002","unstructured":"Haggarty P: Placental regulation of fatty acid delivery and its effect on fetal growth \u2013 a review. Placenta. 2002, 23 (Suppl A): S28-38. 10.1053\/plac.2002.0791","journal-title":"Placenta"},{"key":"208_CR11","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/0378-3782(81)90016-5","volume":"5","author":"MT Clandinin","year":"1981","unstructured":"Clandinin MT, Chappell JE, Heim T, Swyer PR, Chance GW: Fatty acid utilization in perinatal de novo synthesis of tissues. Early Hum Dev. 1981, 5: 355-66. 10.1016\/0378-3782(81)90016-5","journal-title":"Early Hum Dev"},{"key":"208_CR12","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/0163-7827(95)00010-0","volume":"35","author":"RG Jensen","year":"1996","unstructured":"Jensen RG: The lipids in human milk. Prog Lipid Res. 1996, 35: 53-92. 10.1016\/0163-7827(95)00010-0","journal-title":"Prog Lipid Res"},{"key":"208_CR13","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1007\/s11745-997-0137-6","volume":"32","author":"ZY Chen","year":"1997","unstructured":"Chen ZY, Kwan KY, Tong KK, Ratnayake WM, Li HQ, Leung SS: Breast milk fatty acid composition: a comparative study between Hong Kong and Chongqing Chinese. Lipids. 1997, 32: 1061-7. 10.1007\/s11745-997-0137-6","journal-title":"Lipids"},{"key":"208_CR14","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/978-1-4757-4242-8_5","volume":"554","author":"SM Innis","year":"2004","unstructured":"Innis SM: Polyunsaturated fatty acids in human milk: an essential role in infant development. Adv Exp Med Biol. 2004, 554: 27-43.","journal-title":"Adv Exp Med Biol"},{"key":"208_CR15","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1080\/10408690590956378","volume":"45","author":"M Fleith","year":"2005","unstructured":"Fleith M, Clandinin MT: Dietary PUFA for preterm and term infants: review of clinical studies. Crit Rev Food Sci Nutr. 2005, 45: 205-29. 10.1080\/10408690590956378","journal-title":"Crit Rev Food Sci Nutr"},{"key":"208_CR16","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1054\/plef.2002.0446","volume":"67","author":"SR De Vriese","year":"2002","unstructured":"De Vriese SR, Matthys C, De Henauw S, De Backer G, Dhont M, Christophe AB: Maternal and umbilical fatty acid status in relation to maternal diet. Prostagland Leukot Essent Fatty Acids. 2002, 67: 389-96. 10.1054\/plef.2002.0446.","journal-title":"Prostagland Leukot Essent Fatty Acids"},{"key":"208_CR17","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1159\/000091685","volume":"50","author":"AS Olafsdottir","year":"2006","unstructured":"Olafsdottir AS, Thorsdottir I, Wagner KH, Elmadfa I: Polyunsaturated fatty acids in the diet and breast milk of lactating icelandic women with traditional fish and cod liver oil consumption. Ann Nutr Metab. 2006, 50: 270-6. 10.1159\/000091685","journal-title":"Ann Nutr Metab"},{"key":"208_CR18","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/ajcn\/85.6.1457","volume":"85","author":"JT Brenna","year":"2007","unstructured":"Brenna JT, Varamini B, Jensen RG, Diersen-Schade DA, Boettcher JA, Arterburn LM: Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007, 85: 1457-64.","journal-title":"Am J Clin Nutr"},{"key":"208_CR19","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1097\/01.mpg.0000176181.66390.54","volume":"41","author":"A Kovacs","year":"2005","unstructured":"Kovacs A, Funke S, Marosvolgyi T, Burus I, Decsi T: Fatty acids in early human milk after preterm and full-term delivery. J Pediatr Gastroenterol Nutr. 2005, 41: 454-9. 10.1097\/01.mpg.0000176181.66390.54","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"208_CR20","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1093\/ajcn\/38.2.300","volume":"38","author":"J Bitman","year":"1983","unstructured":"Bitman J, Wood L, Hamosh M, Hamosh P, Mehta NR: Comparison of the lipid composition of breast milk from mothers of term and preterm infants. Am J Clin Nutr. 1983, 38: 300-12.","journal-title":"Am J Clin Nutr"},{"key":"208_CR21","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/00005176-199404000-00018","volume":"18","author":"P Luukkainen","year":"1994","unstructured":"Luukkainen P, Salo MK, Nikkari T: Changes in the fatty acid composition of preterm and term human milk from 1 week to 6 months of lactation. J Pediatr Gastroenterol Nutr. 1994, 18: 355-60.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"208_CR22","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1007\/s004310050573","volume":"156","author":"O Genzel-Boroviczeny","year":"1997","unstructured":"Genzel-Boroviczeny O, Wahle J, Koletzko B: Fatty acid composition of human milk during the 1st month after term and preterm delivery. Eur J Pediatr. 1997, 156: 142-7. 10.1007\/s004310050573","journal-title":"Eur J Pediatr"},{"key":"208_CR23","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1159\/000093230","volume":"66","author":"PL Hofman","year":"2006","unstructured":"Hofman PL, Regan F, Cutfield WS: Prematurity \u2013 another example of perinatal metabolic programming?. Horm Res. 2006, 66: 33-9. 10.1159\/000093230","journal-title":"Horm Res"},{"issue":"Suppl 1","key":"208_CR24","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.1017\/S0007114500000969","volume":"83","author":"SD Clarke","year":"2000","unstructured":"Clarke SD: Polyunsaturated fatty acid regulation of gene transcription: a mechanism to improve energy balance and insulin resistance. Br J Nutr. 2000, 83 (Suppl 1): S59-66.","journal-title":"Br J Nutr"},{"key":"208_CR25","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1542\/peds.2006-0018","volume":"118","author":"TN Raju","year":"2006","unstructured":"Raju TN, Higgins RD, Stark AR, Leveno KJ: Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics. 2006, 118: 1207-14. 10.1542\/peds.2006-0018","journal-title":"Pediatrics"},{"key":"208_CR26","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1111\/j.1651-2227.2004.tb00853.x","volume":"93","author":"L Schermann","year":"2004","unstructured":"Schermann L, Sedin G: Cognitive function at 10 years of age in children who have required neonatal intensive care. Acta Paediatr. 2004, 93: 1619-29. 10.1080\/08035250410023386","journal-title":"Acta Paediatr"},{"key":"208_CR27","doi-asserted-by":"publisher","first-page":"F474","DOI":"10.1136\/adc.2004.070284","volume":"90","author":"B Caravale","year":"2005","unstructured":"Caravale B, Tozzi C, Albino G, Vicari S: Cognitive development in low risk preterm infants at 3\u20134 years of life. Arch Dis Child Fetal Neonat. 2005, 90: F474-9. 10.1136\/adc.2004.070284.","journal-title":"Arch Dis Child Fetal Neonat"},{"key":"208_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/01460860590913945","volume":"28","author":"MM McGrath","year":"2005","unstructured":"McGrath MM, Sullivan M, Devin J: Early precursors of low attention and hyperactivity in a preterm sample at age four. Iss Compr Pediatr Nurs. 2005, 28: 1-15. 10.1080\/01460860590913945.","journal-title":"Iss Compr Pediatr Nurs"},{"key":"208_CR29","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1054\/plef.2000.0177","volume":"63","author":"AP Simopoulos","year":"2000","unstructured":"Simopoulos AP: Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. Prostagland Leukot Essent Fatty Acids. 2000, 63: 123-4. 10.1054\/plef.2000.0177.","journal-title":"Prostagland Leukot Essent Fatty Acids"},{"key":"208_CR30","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1471-2431-8-8","volume":"8","author":"A Niklasson","year":"2008","unstructured":"Niklasson A, Albertsson-Wikland K: Continuous growth reference from 24th week of gestation to 24 months by gender. BMC Pediatr. 2008, 8: 8- 10.1186\/1471-2431-8-8","journal-title":"BMC Pediatr"},{"key":"208_CR31","volume-title":"Nutrtion Recommendations 2004, integrating nutrtion and physical activity","author":"Nordic Council of Ministers","year":"2004","unstructured":"Nordic Council of Ministers: Nutrtion Recommendations 2004, integrating nutrtion and physical activity. 2004, Copenhagen, Denmark; Nord, 4,","edition":"4"},{"key":"208_CR32","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1111\/j.1651-2227.2007.00482.x","volume":"96","author":"YM Peng","year":"2007","unstructured":"Peng YM, Zhang TY, Wang Q, Zetterstrom R, Strandvik B: Fatty acid composition in breast milk and serum phospholipids of healthy term Chinese infants during first 6 weeks of life. Acta Paediatr. 2007, 96: 1640-5. 10.1111\/j.1651-2227.2007.00482.x","journal-title":"Acta Paediatr"},{"key":"208_CR33","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/jn\/70.3.405","volume":"70","author":"RT Holman","year":"1960","unstructured":"Holman RT: The ratio of trienoic: tetraenoic acids in tissue lipids as a measure of essential fatty acid requirement. J Nutr. 1960, 70: 405-10.","journal-title":"J Nutr"},{"key":"208_CR34","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1016\/0140-6736(92)90533-9","volume":"339","author":"SF Olsen","year":"1992","unstructured":"Olsen SF, Sorensen JD, Secher NJ, Hedegaard M, Henriksen TB, Hansen HS, Grant A: Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration. Lancet. 1992, 339: 1003-7. 10.1016\/0140-6736(92)90533-9","journal-title":"Lancet"},{"key":"208_CR35","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s11745-997-0067-3","volume":"32","author":"P Guesnet","year":"1997","unstructured":"Guesnet P, Alasnier C, Alessandri JM, Durand G: Modifying the n-3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat. Lipids. 1997, 32: 527-34. 10.1007\/s11745-997-0067-3","journal-title":"Lipids"},{"key":"208_CR36","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1203\/01.pdr.0000190569.07991.ed","volume":"59","author":"SC Cunnane","year":"2006","unstructured":"Cunnane SC, Ryan MA, Lin YH, Lim SY, Salem N: Suckling rats actively recycle carbon from alpha-linolenate into newly synthesized lipids even during extreme dietary deficiency of n-3 polyunsaturates. Pediatr Res. 2006, 59: 107-10.","journal-title":"Pediatr Res"},{"key":"208_CR37","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1203\/01.pdr.0000182188.31596.5a","volume":"58","author":"GJ Anderson","year":"2005","unstructured":"Anderson GJ, Neuringer M, Lin DS, Connor WE: Can prenatal N-3 fatty acid deficiency be completely reversed after birth? Effects on retinal and brain biochemistry and visual function in rhesus monkeys. Pediatr Res. 2005, 58: 865-72. 10.1203\/01.pdr.0000182188.31596.5a","journal-title":"Pediatr Res"},{"key":"208_CR38","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1203\/00006450-199607000-00029","volume":"40","author":"VP Carnielli","year":"1996","unstructured":"Carnielli VP, Wattimena DJ, Luijendijk IH, Boerlage A, Degenhart HJ, Sauer PJ: The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. Pediatr Res. 1996, 40: 169-74. 10.1203\/00006450-199607000-00029","journal-title":"Pediatr Res"},{"key":"208_CR39","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1073\/pnas.93.1.49","volume":"93","author":"N Salem Jr","year":"1996","unstructured":"Salem N, Wegher B, Mena P, Uauy R: Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants. Proc Natl Acad Sci USA. 1996, 93: 49-54. 10.1073\/pnas.93.1.49","journal-title":"Proc Natl Acad Sci USA"},{"key":"208_CR40","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1203\/00006450-200001000-00022","volume":"47","author":"R Uauy","year":"2000","unstructured":"Uauy R, Mena P, Wegher B, Nieto S, Salem N: Long chain polyunsaturated fatty acid formation in neonates: effect of gestational age and intrauterine growth. Pediatr Res. 2000, 47: 127-35. 10.1203\/00006450-200001000-00022","journal-title":"Pediatr Res"},{"key":"208_CR41","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1093\/hmg\/ddl117","volume":"15","author":"L Schaeffer","year":"2006","unstructured":"Schaeffer L, Gohlke H, Muller M, Heid IM, Palmer LJ, Kompauer I, Demmelmair H, Illig T, Koletzko B, Heinrich J: Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet. 2006, 15: 1745-56. 10.1093\/hmg\/ddl117","journal-title":"Hum Mol Genet"},{"key":"208_CR42","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1053\/siny.2001.0093","volume":"6","author":"SE Carlson","year":"2001","unstructured":"Carlson SE: Docosahexaenoic acid and arachidonic acid in infant development. Semin Neonatol. 2001, 6: 437-49. 10.1053\/siny.2001.0093","journal-title":"Semin Neonatol"},{"key":"208_CR43","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/S1388-1981(00)00077-9","volume":"1486","author":"H Sprecher","year":"2000","unstructured":"Sprecher H: Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim Biophys Acta. 2000, 1486: 219-31.","journal-title":"Biochim Biophys Acta"},{"key":"208_CR44","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1067\/S0022-3476(03)00396-2","volume":"143","author":"SM Innis","year":"2003","unstructured":"Innis SM: Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids. J Pediatr. 2003, 143: S1-8.","journal-title":"J Pediatr"},{"key":"208_CR45","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1194\/jlr.M500407-JLR200","volume":"47","author":"M Rodriguez-Cruz","year":"2006","unstructured":"Rodriguez-Cruz M, Tovar AR, Palacios-Gonzalez B, Del Prado M, Torres N: Synthesis of long-chain polyunsaturated fatty acids in lactating mammary gland: role of Delta5 and Delta6 desaturases, SREBP-1, PPARalpha, and PGC-1. J Lipid Res. 2006, 47: 553-60. 10.1194\/jlr.M500407-JLR200","journal-title":"J Lipid Res"},{"key":"208_CR46","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/sj.ejcn.1600390","volume":"51","author":"SJ Otto","year":"1997","unstructured":"Otto SJ, van Houwelingen AC, Antal M, Manninen A, Godfrey K, L\u00f3pez-Jaramillo P, Hornstra G: Maternal and neonatal essential fatty acid status in phospholipids: an international comparative study. Eur J Clin Nutr . 1997, 51: 232-42. 10.1038\/sj.ejcn.1600390","journal-title":"Eur J Clin Nutr"},{"key":"208_CR47","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1515\/CCLM.2002.044","volume":"40","author":"S Garcia-Calatayud","year":"2002","unstructured":"Garcia-Calatayud S, Ruiz JI, Garcia-Fuentes M, Dierssen M, Florez J, Crespo PS: Long-chain polyunsaturated fatty acids in rat maternal milk, offspring brain and peripheral tissues in essential fatty acid deficiency. Clin Chem Lab Med. 2002, 40: 278-84. 10.1515\/CCLM.2002.044","journal-title":"Clin Chem Lab Med"},{"key":"208_CR48","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1038\/sj.ejcn.1600444","volume":"51","author":"MD Al","year":"1997","unstructured":"Al MD, van Houwelingen AC, Hornstra G: Relation between birth order and the maternal and neonatal docosahexaenoic acid status. Eur J Clin Nutr. 1997, 51: 548-53. 10.1038\/sj.ejcn.1600444","journal-title":"Eur J Clin Nutr"},{"key":"208_CR49","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.jpeds.2005.05.040","volume":"147","author":"C Agostoni","year":"2005","unstructured":"Agostoni C, Galli C, Riva E, Colombo C, Giovannini M, Marangoni F: Reduced docosahexaenoic acid synthesis may contribute to growth restriction in infants born to mothers who smoke. J Pediatr. 2005, 147: 854-6. 10.1016\/j.jpeds.2005.05.040","journal-title":"J Pediatr"},{"key":"208_CR50","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/S0140-6736(07)60277-3","volume":"369","author":"JR Hibbeln","year":"2007","unstructured":"Hibbeln JR, Davis JM, Steer C, Emmett P, Rogers I, Williams C, Golding J: Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet. 2007, 369: 578-85. 10.1016\/S0140-6736(07)60277-3","journal-title":"Lancet"},{"key":"208_CR51","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1159\/000079821","volume":"48","author":"H Minda","year":"2004","unstructured":"Minda H, Kovacs A, Funke S, Sz\u00e1sz M, Burus I, Moln\u00e1r S, Marosv\u00f6lgyi T, Decsi T: Changes of fatty acid composition of human milk during the first month of lactation: a day-to-day approach in the first week. Ann Nutr Metab. 2004, 48: 202-9. 10.1159\/000079821","journal-title":"Ann Nutr Metab"},{"key":"208_CR52","unstructured":"ESPGAN Committee on Nutrition: Guidelines on infant nutrition. I. Recommendations for the composition of an adapted formula. Acta Paediatr Scand Suppl. 1977, 1-20. 262,"}],"container-title":["Lipids in Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1476-511X-8-20.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T19:04:19Z","timestamp":1630436659000},"score":1,"resource":{"primary":{"URL":"https:\/\/lipidworld.biomedcentral.com\/articles\/10.1186\/1476-511X-8-20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,10]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["208"],"URL":"https:\/\/doi.org\/10.1186\/1476-511x-8-20","relation":{},"ISSN":["1476-511X"],"issn-type":[{"value":"1476-511X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,10]]},"assertion":[{"value":"8 February 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"20"}}