{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:57:05Z","timestamp":1792144625978,"version":"4.4.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Bile duct tumor thrombus (BDTT) of a hepatocellular carcinoma (HCC) is a rare entity which was found microscopically in 1 to 9.2% of the resected specimen.<\/jats:p>\n          <jats:p>A 54-year-old male was found to have a 65-mm hepatocellular carcinoma in segment VI of the liver with a huge intrahepatic bile duct tumor thrombus. As the main trunk of the posterior segment branched from the left bile duct, the BDTT of the posterior branch extended to the common bile duct via the left bile duct. When the posterior segment was resected along with the left lobe, the estimated remnant liver volume was less than 30%. Therefore, the patient underwent extended posterior segmentectomy with choledochotomy and all of the BDTT was removed via the common bile duct.<\/jats:p>\n          <jats:p>Three months later, his serum bilirubin (6.63 mg\/dL) and des-gamma-carboxy prothrombin (410 ng\/mL) were re-elevated due to recurrent BDTT. A well-enhanced BDTT was observed by computed tomography (CT) at the left bile duct. Transarterial chemotherapy with cisplatin was scheduled, followed by endoscopic retrograde bile duct drainage. After four sessions of this chemotherapy, the BDTT had vanished and the tumor marker was decreased to within the normal range. The patient was stably treated with this regimen and has remained recurrence-free for five years.<\/jats:p>","DOI":"10.1186\/1477-7819-11-78","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T15:13:56Z","timestamp":1364051636000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Complete remission by transarterial infusion with cisplatin for recurrent bile duct tumor thrombus of hepatocellular carcinoma: report of a case"],"prefix":"10.1186","volume":"11","author":[{"given":"Chiharu","family":"Ebara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Moriguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Mitsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoya","family":"Funada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tokio","family":"Higaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadatoshi","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,3,23]]},"reference":[{"key":"1278_CR1","doi-asserted-by":"crossref","first-page":"3966","DOI":"10.3748\/wjg.v11.i25.3966","volume":"11","author":"BG Peng","year":"2005","unstructured":"Peng BG, Liang LJ, Li SQ, Zhou F, Hua YP, Luo SM: Surgical treatment of hepatocellular carcinoma with bile duct tumor thrombi. World J Gastroenterol. 2005, 11: 3966-3969.","journal-title":"World J Gastroenterol"},{"key":"1278_CR2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3748\/wjg.v9.i3.385","volume":"9","author":"LX Qin","year":"2003","unstructured":"Qin LX, Tang ZY: Hepatocellular carcinoma with obstructive jaundice: diagnosis, treatment and prognosis. World J Gastroenterol. 2003, 9: 385-391.","journal-title":"World J Gastroenterol"},{"key":"1278_CR3","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1046\/j.1440-1746.2002.02677.x","volume":"17","author":"JF Huang","year":"2002","unstructured":"Huang JF, Wang LY, Lin ZY, Chen SC, Hsieh MY, Chuang WL, Yu MY, Lu SN, Wang JH, Yeung KW, Chang WY: Incidence and clinical outcome of icteric type hepatocellular carcinoma. J Gastroenterol Hepatol. 2002, 17: 190-195. 10.1046\/j.1440-1746.2002.02677.x.","journal-title":"J Gastroenterol Hepatol"},{"key":"1278_CR4","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/S0960-7404(10)80042-8","volume":"4","author":"WY Lau","year":"1995","unstructured":"Lau WY, Leung KL, Leung TW, Ho S, Chan M, Liew CK, Leung N, Johnson P, Li AK: Obstructive jaundice secondary to hepatocellular carcinoma. Surg Oncol. 1995, 4: 303-308. 10.1016\/S0960-7404(10)80042-8.","journal-title":"Surg Oncol"},{"key":"1278_CR5","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1067\/msy.2001.113889","volume":"129","author":"M Shiomi","year":"2001","unstructured":"Shiomi M, Kamiya J, Nagino M, Uesaka K, Sano T, Hayakawa N, Kanai M, Yamamoto H, Nimura Y: Hepatocellular carcinoma with biliary tumor thrombi: aggressive operative approach after appropriate preoperative management. Surgery. 2001, 129: 692-698. 10.1067\/msy.2001.113889.","journal-title":"Surgery"},{"key":"1278_CR6","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/s00268-004-7185-y","volume":"28","author":"CN Yeh","year":"2004","unstructured":"Yeh CN, Jan YY, Lee WC, Chen MF: Hepatic resection for hepatocellular carcinoma with obstructive jaundice due to biliary tumour thrombi. World J Surg. 2004, 28: 471-475. 10.1007\/s00268-004-7185-y.","journal-title":"World J Surg"},{"key":"1278_CR7","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1002\/cncr.21043","volume":"103","author":"DY Kim","year":"2005","unstructured":"Kim DY, Park W, Lim DH, Lee JH, Yoo BC, Paik SW, Kho KC, Kim TH, Ahn YC, Huh SJ: Three-dimensional conformal radiotherapy for portal vein thrombosis of hepatocellular carcinoma. Cancer. 2005, 103: 2419-2426. 10.1002\/cncr.21043.","journal-title":"Cancer"},{"key":"1278_CR8","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1002\/(SICI)1097-0142(19970601)79:11<2087::AID-CNCR5>3.0.CO;2-M","volume":"79","author":"HS Lee","year":"1997","unstructured":"Lee HS, Kim JS, Choi IJ, Chung JW, Park JH, Kim CY: The safety and efficacy of transcatheter arterial chemoembolization in the treatment of patients with hepatocellular carcinoma and main portal vein obstruction. A prospective controlled study. Cancer. 1997, 79: 2087-2094. 10.1002\/(SICI)1097-0142(19970601)79:11<2087::AID-CNCR5>3.0.CO;2-M.","journal-title":"Cancer"},{"key":"1278_CR9","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1097\/CAD.0b013e328342231d","volume":"22","author":"H Yodono","year":"2011","unstructured":"Yodono H, Matsuo K, Shinohara A: A retrospective comparative study of epirubicin-lipiodol emulsion and cisplatin-lipiodol suspension for use with transcatheter arterial chemoembolization for treatment of hepatocellular carcinoma. Anticancer Drugs. 2011, 22: 277-282. 10.1097\/CAD.0b013e328342231d.","journal-title":"Anticancer Drugs"},{"key":"1278_CR10","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1093\/jjco\/hyr037","volume":"41","author":"S Iwasa","year":"2011","unstructured":"Iwasa S, Ikeda M, Okusaka T, Ueno H, Morizane C, Nakachi K, Mitsunaga S, Kondo S, Hagihara A, Shimizu S, Satake M, Arai Y: Transcatheter arterial infusion chemotherapy with a fine-powder formulation of cisplatin for advanced hepatocellular carcinoma refractory to transcatheter arterial chemoembolization. Jpn J Clin Oncol. 2011, 41: 770-775. 10.1093\/jjco\/hyr037.","journal-title":"Jpn J Clin Oncol"},{"key":"1278_CR11","first-page":"3991","volume":"31","author":"T Kurokawa","year":"2011","unstructured":"Kurokawa T, Yamazaki S, Moriguchi M, Aoki M, Watanabe Y, Higaki T, Takayama T: Resection of solitary metachronous lymph node metastasis from hepatocellular carcinoma following transarterial chemotherapy with cisplatin: a case report. Anticancer Res. 2011, 31: 3991-3993.","journal-title":"Anticancer Res"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1477-7819-11-78.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T22:58:43Z","timestamp":1630537123000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjso.biomedcentral.com\/articles\/10.1186\/1477-7819-11-78"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,23]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["1278"],"URL":"https:\/\/doi.org\/10.1186\/1477-7819-11-78","relation":{},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,23]]},"assertion":[{"value":"19 December 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"78"}}