{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T07:37:16Z","timestamp":1768462636685,"version":"3.49.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Surg Onc"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                        <jats:title>Background<\/jats:title>\n                        <jats:p>Dedifferentiated liposarcomas represent heterogeneous tumors with lipomatous and nonlipomatous elements starkly juxtaposed. It is thought that the high grade nonlipomatous elements of the tumor portend a worse prognosis.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Case Presentation<\/jats:title>\n                        <jats:p>A 19.8 kg heterogeneous retroperitoneal tumor was successfully and completely resected. Because of its extent, no additional treatment modalities were practicable. The tumor soon recurred. The recurrent tumor differed from the primary tumor in that it was more homogeneous, consisting mainly of nonlipogenic, calcific tissue.<\/jats:p>\n                     <\/jats:sec><jats:sec>\n                        <jats:title>Conclusions<\/jats:title>\n                        <jats:p>Dedifferentiated liposarcomas are known to have a very high recurrence rate. The biological behavior of dedifferentiated liposarcomas is likely dictated by the most aggressive element of these heterogeneous tumors.<\/jats:p>\n                     <\/jats:sec>","DOI":"10.1186\/1477-7819-2-25","type":"journal-article","created":{"date-parts":[[2004,7,27]],"date-time":"2004-07-27T06:23:22Z","timestamp":1090909402000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A unique dedifferentiated tumor of the retroperitoneum"],"prefix":"10.1186","volume":"2","author":[{"given":"Shahzeer","family":"Karmali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halligrimur","family":"Benediktson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walley","family":"Temple","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver F","family":"Bathe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,7,23]]},"reference":[{"key":"55_CR1","first-page":"401","volume-title":"In: Surgical Oncology","author":"MS Brady","year":"1996","unstructured":"Brady MS, Brennan MF: Soft tissue sarcoma. In: Surgical Oncology. Edited by: allen-Mersh TG. 1996, Longon: Chapman and Hall, 401-20."},{"key":"55_CR2","first-page":"623","volume":"148","author":"CD Fletcher","year":"1996","unstructured":"Fletcher CD, Akerman M, Dal Cin P, de Wever I, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Sciot R, Tallini G, van den Berghe H, van de Ven W, Vanni R, Willen H: Correlation between clinicopathological features and karyotypes in lipomatous tumors. Am J Pathol. 1996, 148: 623-630.","journal-title":"Am J Pathol"},{"key":"55_CR3","first-page":"263","volume":"18","author":"AG Nascimento","year":"2001","unstructured":"Nascimento AG: Dedifferentiated liposarcoma. Semin Diagn Pathol. 2001, 18: 263-266.","journal-title":"Semin Diagn Pathol"},{"key":"55_CR4","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1097\/00000478-199703000-00002","volume":"21","author":"WH Henricks","year":"1997","unstructured":"Henricks WH, Chu YC, Goldblum JR, Weiss SW: Dedifferentiated liposarcoma: A clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am J Surg Pathol. 1997, 21: 271-281. 10.1097\/00000478-199703000-00002.","journal-title":"Am J Surg Pathol"},{"key":"55_CR5","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1097\/00004728-200309000-00019","volume":"27","author":"U Tateishi","year":"2003","unstructured":"Tateishi U, Hasegawa T, Beppu Y, Satake M, Moriyama N: Primary dedifferentiated liposarcoma of the retroperitoneum. Prognostic significance of computed tomography and magnetic resonance imaging features. J Comput Assist Tomogr. 2003, 27: 799-804. 10.1097\/00004728-200309000-00019.","journal-title":"J Comput Assist Tomogr"},{"key":"55_CR6","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1097\/01.MP.0000056983.78547.77","volume":"16","author":"JM Coindre","year":"2003","unstructured":"Coindre JM, Mariani O, Chibon F, Mairal A, De Saint Aubain Somerhausen N, Favre-Guillevin E, Bui NB, Stoeckle E, Hostein I, Aurias A: Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: A review of 25 cases initially diagnosed as malignant fibrous histiocytoma. Mod Pathol. 2003, 16: 256-262. 10.1097\/01.MP.0000056983.78547.77.","journal-title":"Mod Pathol"},{"key":"55_CR7","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1097\/00000478-199412000-00004","volume":"18","author":"D McCormick","year":"1994","unstructured":"McCormick D, Mentzel T, Beham A, Fletcher CD: Dedifferentiated liposarcoma: clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among the pleomorphic sarcomas. Am J Surg Pathol. 1994, 18: 1213-1223.","journal-title":"Am J Surg Pathol"},{"key":"55_CR8","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1097\/00000478-199808000-00004","volume":"22","author":"AG. Nascimento","year":"1998","unstructured":"Nascimento AG., Kurtin PJ, Guillou L, Fletcher CD: Dedifferentiated liposarcoma: a report of nine cases showing a peculiar neural-like (whirling) pattern associated with metaplastic bone formation. Am J Surg Pathol. 1998, 22: 945-955. 10.1097\/00000478-199808000-00004.","journal-title":"Am J Surg Pathol"},{"key":"55_CR9","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1097\/01.sla.0000086542.11899.38","volume":"238","author":"S Singer","year":"2003","unstructured":"Singer S, Antonescu CR, Riedel E, Brennan MF: Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003, 238: 358-371. 10.1097\/01.sla.0000086542.11899.38.","journal-title":"Ann Surg"},{"key":"55_CR10","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1001\/archsurg.1991.01410270072012","volume":"126","author":"RG Bevilacqua","year":"1991","unstructured":"Bevilacqua RG, Rogatko A, Hajdu SI, Brennan MF: Prognostic factors in primary retroperitoneal soft tissue sarcomas. Arch Surg. 1991, 126: 328-334.","journal-title":"Arch Surg"}],"container-title":["World Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1477-7819-2-25.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:05:11Z","timestamp":1728302711000},"score":1,"resource":{"primary":{"URL":"https:\/\/wjso.biomedcentral.com\/articles\/10.1186\/1477-7819-2-25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7,23]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,12]]}},"alternative-id":["55"],"URL":"https:\/\/doi.org\/10.1186\/1477-7819-2-25","relation":{},"ISSN":["1477-7819"],"issn-type":[{"value":"1477-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,7,23]]},"assertion":[{"value":"30 April 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"25"}}