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We report a case of primary liposarcoma of the colon presenting as a massive intraluminal lesion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 79-year-old woman presented with abdominal pain, progressive constipation and weight loss. A CT scan and a colonoscopy revealed an intraluminal mass in the transverse colon and multiple intraperitoneal lesions. The patient underwent surgical resection of the lesions. Pathologic examination was consistent with pleomorphic liposarcoma of the colon.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although no guidelines are available for the management of liposarcoma of the colon, surgical resection should be performed when feasible. Our patient's overall survival was satisfactory in spite of the multiple negative prognostic factors.<\/jats:p><\/jats:sec>","DOI":"10.1186\/1477-7819-7-78","type":"journal-article","created":{"date-parts":[[2009,10,24]],"date-time":"2009-10-24T06:13:34Z","timestamp":1256364814000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Liposarcoma of the colon presenting as an endoluminal mass"],"prefix":"10.1186","volume":"7","author":[{"given":"Marco","family":"D'Annibale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Cosimelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Covello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Stasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,10,23]]},"reference":[{"issue":"1","key":"615_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2559.2005.02284.x","volume":"48","author":"CD Fletcher","year":"2006","unstructured":"Fletcher CD: The evolving classification of soft tissue tumours: an update based on the new WHO classification. 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