{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:33:16Z","timestamp":1787319196804,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod Biol Endocrinol"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Septate uterus, one of the most common forms of congenital uterine malformations, negatively affects female reproductive health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a retrospective cohort study, we evaluated the reproductive outcome after hysteroscopic septoplasty in 64 women with septate uterus and primary or secondary infertility. We performed a systematic review of studies evaluating the reproductive outcome after hysteroscopic septoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty-four women underwent hysteroscopic septoplasty. In 2\/64 (3%) women, intraoperative uterine perforation occurred. Complete follow-up was available for 49\/64 (76%) patients. Mean follow-up time was 68.6 +\/- 5.2 months. The overall pregnancy rate after hysteroscopic septoplasty was 69% (34\/49). The overall life birth rate (LBR) was 49% (24\/49). The mean time interval between surgery and the first life birth was 35.8 +\/- 22.5 months. Including our own data, we identified 18 studies investigating the effect of septoplasty on reproductive outcome in 1501 women. A pooled analysis demonstrated that hysteroscopic septoplasty resulted in an overall pregnancy rate of 60% (892\/1501) and a LBR of 45% (686\/1501). The overall rate of intra- and postoperative complications was 1.7% (23\/1324) and the overall rate of re-hysteroscopy was 6% (79\/1324).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In women with septate uterus and a history of infertility, hysteroscopic septoplasty is a safe and effective procedure resulting in a pregnancy rate of 60% and a LBR of 45%.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/1477-7827-8-52","type":"journal-article","created":{"date-parts":[[2010,6,15]],"date-time":"2010-06-15T02:16:35Z","timestamp":1276568195000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["Reproductive outcome after hysteroscopic septoplasty in patients with septate uterus - a retrospective cohort study and systematic review of the literature"],"prefix":"10.1186","volume":"8","author":[{"given":"Kazem","family":"Nouri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Ott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes C","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva-Maria","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucija","family":"St\u00f6gbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemens B","family":"Tempfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,5,21]]},"reference":[{"key":"677_CR1","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1093\/humupd\/7.2.161","volume":"7","author":"GF Grimbizis","year":"2001","unstructured":"Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Devroey P: Clinical implications of uterine malformations and hysteroscopic treatment results. 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