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The prothrombotic status of a patient with antiphospholipid antibodies (APL), a past history of mesenteric vein thrombosis and presenting myocardial infarction and extensive intracardiac thrombosis was examined by measurement of circulating procoagulant MP. MP of platelet and endothelial origins were highly elevated with respect to values detectable in patients with myocardial infarction and no history of APS (6- and 3-fold elevation, respectively) or in healthy volunteers (13- and 25-fold elevation, respectively). In this particular patient, with moderate APL titer, a drastic release of procoagulant MP could have contributed to thrombus growth and the development of extensive intracardiac thrombosis.<\/jats:p>","DOI":"10.1186\/1477-9560-3-15","type":"journal-article","created":{"date-parts":[[2005,10,11]],"date-time":"2005-10-11T18:14:25Z","timestamp":1129054465000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Elevated levels of procoagulant microparticles in a patient with myocardial infarction, antiphospholipid antibodies and multifocal cardiac thrombosis"],"prefix":"10.1186","volume":"3","author":[{"given":"O","family":"Morel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Jesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JM","family":"Freyssinet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Toti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,10,11]]},"reference":[{"key":"34_CR1","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1046\/j.1538-7836.2003.00125.x","volume":"1","author":"J Arnout","year":"2003","unstructured":"Arnout J, Vermylen J: Current status and implications of autoimmune antiphospholipid in relation to thrombotic disease. 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