{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:11:21Z","timestamp":1792113081861,"version":"4.4.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T00:00:00Z","timestamp":1403481600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Transl Med"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1479-5876-12-180","type":"journal-article","created":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T15:19:24Z","timestamp":1403536764000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Overexpression of BID in thyroids of transgenic mice increases sensitivity to iodine-induced autoimmune thyroiditis"],"prefix":"10.1186","volume":"12","author":[{"given":"Su He","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongyi","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"James R","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,6,23]]},"reference":[{"key":"1889_CR1","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.4049\/jimmunol.168.5.2470","volume":"168","author":"SH Wang","year":"2002","unstructured":"Wang SH, Bretz JD, Phelps E, Mezosi E, Arscott PL, Utsugi S, Baker JR: A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditis. J Immunology. 2002, 168: 2470-2474. 10.4049\/jimmunol.168.5.2470.","journal-title":"J Immunology"},{"key":"1889_CR2","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1210\/me.2004-0286","volume":"19","author":"E Mezosi","year":"2005","unstructured":"Mezosi E, Wang SH, Utsugi S, Bajnok L, Bretz JD, Gauger PG, Thompson NW, Baker JR: Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells. Mol Endocrinology. 2005, 19: 804-811. 10.1210\/me.2004-0286.","journal-title":"Mol Endocrinology"},{"key":"1889_CR3","doi-asserted-by":"publisher","first-page":"4844","DOI":"10.1210\/en.2007-0126","volume":"148","author":"SH Wang","year":"2007","unstructured":"Wang SH, Van Antwerp M, Kuick R, Gauger PG, Doherty GM, Fan YY, Baker JR: Microarray analysis of cytokine activation of apoptosis pathways in the thyroid. Endocrinology. 2007, 148: 4844-4852. 10.1210\/en.2007-0126.","journal-title":"Endocrinology"},{"key":"1889_CR4","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1210\/en.2008-1389","volume":"150","author":"SH Wang","year":"2009","unstructured":"Wang SH, Chen GH, Fan YY, Van Antwerp M, Baker JR: TRAIL inhibits experimental autoimmune thyroiditis by the expansion of CD4\u2009+\u2009CD25+ regulatory T cells. Endocrinology. 2009, 150: 2000-2007. 10.1210\/en.2008-1389.","journal-title":"Endocrinology"},{"key":"1889_CR5","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.jaut.2012.04.006","volume":"39","author":"V Paunovic","year":"2012","unstructured":"Paunovic V, Carter NA, Thalhamer T, Blair D, Gordon B, Lacey E, Michie AM, Harnett MM: Immune complex-mediated co-ligation of the BCR with Fc\u03b3RIIB results in homeostatic apoptosis of B cells involving Fas signalling that is defective in the MRL\/Lpr model of systemic lupus erythematosus. J Autoimmun. 2012, 39: 332-346. 10.1016\/j.jaut.2012.04.006.","journal-title":"J Autoimmun"},{"key":"1889_CR6","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.jbiotec.2011.10.007","volume":"157","author":"N Askari","year":"2012","unstructured":"Askari N, Correa RG, Zhai D, Reed JC: Expression, purification, and characterization of recombinant NOD1 (NLRC1): A NLR family member. J Biotechnol. 2012, 157: 75-81. 10.1016\/j.jbiotec.2011.10.007.","journal-title":"J Biotechnol"},{"key":"1889_CR7","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1177\/0961203310382128","volume":"20","author":"A Midgley","year":"2011","unstructured":"Midgley A, Mayer K, Edwards SW, Beresford MW: Differential expression of factors involved in the intrinsic and extrinsic apoptotic pathways in juvenile systemic lupus erythematosus. Lupus. 2011, 20: 71-79. 10.1177\/0961203310382128.","journal-title":"Lupus"},{"key":"1889_CR8","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1006\/jaut.1999.0272","volume":"12","author":"H Braley-Mullen","year":"1999","unstructured":"Braley-Mullen H, Sharp GC, Medling B, Tang H: Spontaneous autoimmune thyroiditis in NOD.H-2\u00a0h4 mice. J Autoimmun. 1999, 12: 157-165. 10.1006\/jaut.1999.0272.","journal-title":"J Autoimmun"},{"key":"1889_CR9","doi-asserted-by":"publisher","first-page":"52","DOI":"10.2174\/187221510790410787","volume":"4","author":"Y Fang","year":"2010","unstructured":"Fang Y, Zhao L, Yan F: Chemokines as novel therapeutic targets in autoimmune thyroiditis. Recent Pat DNA Gene Seq. 2010, 4: 52-57. 10.2174\/187221510790410787.","journal-title":"Recent Pat DNA Gene Seq"},{"key":"1889_CR10","doi-asserted-by":"publisher","first-page":"2747","DOI":"10.1210\/en.2007-0082","volume":"148","author":"HS Li","year":"2007","unstructured":"Li HS, Carayanniotis G: Induction of goitrous hypothyroidism by dietary iodide in SJL mice. Endocrinology. 2007, 148: 2747-2752. 10.1210\/en.2007-0082.","journal-title":"Endocrinology"},{"key":"1889_CR11","doi-asserted-by":"publisher","first-page":"4721","DOI":"10.1210\/en.2005-0627","volume":"146","author":"SH Wang","year":"2005","unstructured":"Wang SH, Cao Z, Wolf JM, Van Antwerp M, Baker JR: Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis. Endocrinology. 2005, 146: 4721-4726. 10.1210\/en.2005-0627.","journal-title":"Endocrinology"},{"key":"1889_CR12","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S1568-9972(01)00016-7","volume":"1","author":"NR Rose","year":"2002","unstructured":"Rose NR, Bonita R, Burek CL: Iodine: an environmental trigger of thyroiditis. Autoimmun Rev. 2002, 1: 97-103. 10.1016\/S1568-9972(01)00016-7.","journal-title":"Autoimmun Rev"},{"key":"1889_CR13","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1007\/s12011-010-8815-x","volume":"143","author":"H Xue","year":"2011","unstructured":"Xue H, Wang W, Shan Z, Li Y, Li Y, Teng X, Gao Y, Fan C, Teng W: Dynamic changes of CD4\u2009+\u2009CD25\u2009+\u2009regulatory T cells in NOD.H-2\u00a0h4 mice with iodine-induced autoimmune thyroiditis. Biol Trace Elem Res. 2011, 143: 292-301. 10.1007\/s12011-010-8815-x.","journal-title":"Biol Trace Elem Res"},{"key":"1889_CR14","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1038\/sj.onc.1207213","volume":"23","author":"SH Wang","year":"2004","unstructured":"Wang SH, Mezosi E, Wolf JM, Cao Z, Utsugi S, Gauger PG, Doherty GM, Baker JR: IFN\u03b3 sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by up-regulating Bak expression. Oncogene. 2004, 23: 928-935. 10.1038\/sj.onc.1207213.","journal-title":"Oncogene"},{"key":"1889_CR15","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1210\/jc.2003-030697","volume":"89","author":"E Mezosi","year":"2004","unstructured":"Mezosi E, Wang SH, Utsugi S, Bretz JD, Thompson NW, Gauger PG, Baker JR: The combination of IL-1\u03b2 and TNF\u03b1 sensitizes human thyroid epithelial cells to TRAIL by a complex mechanism involving Bid and p42\/44 MAPK. J Clin Endo Metab. 2004, 89: 250-257. 10.1210\/jc.2003-030697.","journal-title":"J Clin Endo Metab"},{"key":"1889_CR16","doi-asserted-by":"publisher","first-page":"584","DOI":"10.2174\/156800910791859515","volume":"10","author":"G Song","year":"2010","unstructured":"Song G, Chen GG, Hu T, Lai PB: Bid stands at the crossroad of stress-response pathways. Curr Cancer Drug Targets. 2010, 10: 584-592. 10.2174\/156800910791859515.","journal-title":"Curr Cancer Drug Targets"},{"key":"1889_CR17","first-page":"558","volume":"2011","author":"C Kantari","year":"1813","unstructured":"Kantari C, Walczak H: Caspase-8 and bid: caught in the act between death receptors and mitochondria. Biochim Biophys Acta. 1813, 2011: 558-563.","journal-title":"Biochim Biophys Acta"},{"key":"1889_CR18","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/978-1-60327-478-4_27","volume-title":"Immunoendocrinology: Scientific and Clinical Aspects","author":"SH Wang","year":"2011","unstructured":"Wang SH, Baker JR: Thyroiditis. Immunoendocrinology: Scientific and Clinical Aspects. Edited by: Eisenbarth GS. 2011, New York, NY: Humana Press, 443-457. 1","edition":"1"},{"key":"1889_CR19","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1530\/JOE-12-0335","volume":"215","author":"M Salzano","year":"2012","unstructured":"Salzano M, Russo E, Postiglione L, Guerra A, Marotta V, Esposito S, Vitale M: Interferon-\u03b3 inhibits integrin-mediated adhesion to fibronectin and survival signaling in thyroid cells. J Endocrinol. 2012, 215: 439-444. 10.1530\/JOE-12-0335.","journal-title":"J Endocrinol"},{"key":"1889_CR20","doi-asserted-by":"publisher","first-page":"35989","DOI":"10.1074\/jbc.M111.254201","volume":"286","author":"BM Sebastian","year":"2011","unstructured":"Sebastian BM, Roychowdhury S, Tang H, Hillian AD, Feldstein AE, Stahl GL, Takahashi K, Nagy LE: Identification of a cytochrome P4502E1\/Bid\/C1q-dependent axis mediating inflammation in adipose tissue after chronic ethanol feeding to mice. J Biol Chem. 2011, 286: 35989-35997. 10.1074\/jbc.M111.254201.","journal-title":"J Biol Chem"},{"key":"1889_CR21","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1038\/nature09982","volume":"474","author":"G Yeretssian","year":"2011","unstructured":"Yeretssian G, Correa RG, Doiron K, Fitzgerald P, Dillon CP, Green DR, Reed JC, Saleh M: Non-apoptotic role of BID in inflammation and innate immunity. Nature. 2011, 474: 96-99. 10.1038\/nature09982.","journal-title":"Nature"},{"key":"1889_CR22","doi-asserted-by":"publisher","first-page":"7723","DOI":"10.1074\/jbc.M610764200","volume":"282","author":"HR Kang","year":"2007","unstructured":"Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA: Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, Bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem. 2007, 282: 7723-7732.","journal-title":"J Biol Chem"},{"key":"1889_CR23","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1089\/thy.2007.0208","volume":"17","author":"SH Wang","year":"2007","unstructured":"Wang SH, Baker JR: The role of apoptosis in thyroid autoimmunity. Thyroid. 2007, 17: 975-979. 10.1089\/thy.2007.0208.","journal-title":"Thyroid"},{"key":"1889_CR24","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1002\/mnfr.200700465","volume":"52","author":"L Schomburg","year":"2008","unstructured":"Schomburg L, K\u00f6hrle J: On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis and human health. Mol Nutr Food Res. 2008, 52: 1235-1246. 10.1002\/mnfr.200700465.","journal-title":"Mol Nutr Food Res"},{"key":"1889_CR25","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1365-2249.2005.02908.x","volume":"142","author":"JG Barin","year":"2005","unstructured":"Barin JG, Talor MV, Sharma RB, Rose NR, Burek CL: Iodination of murine thyroglobulin enhances autoimmune reactivity in the NOD.H2 mouse. Clin Exp Immunol. 2005, 142: 251-259. 10.1111\/j.1365-2249.2005.02908.x.","journal-title":"Clin Exp Immunol"}],"container-title":["Journal of Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1479-5876-12-180.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1479-5876-12-180\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1479-5876-12-180.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T21:33:39Z","timestamp":1581975219000},"score":1,"resource":{"primary":{"URL":"https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/1479-5876-12-180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,23]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["1889"],"URL":"https:\/\/doi.org\/10.1186\/1479-5876-12-180","relation":{},"ISSN":["1479-5876"],"issn-type":[{"value":"1479-5876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,23]]},"assertion":[{"value":"17 March 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"180"}}