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Then, we give a novel 2D graphical representation for DNA sequences, which can transform a DNA sequence into a plot set to facilitate quantitative comparisons of DNA sequences. Thereafter, associating with a newly designed measure of similarity, we introduce a novel approach to make similarities\/dissimilarities analysis of DNA sequences. Finally, the applications in similarities\/dissimilarities analysis of the complete coding sequences of \u03b2-globin genes of 11 species illustrate the utilities of our newly proposed method.<\/jats:p>","DOI":"10.1186\/1687-4153-2014-1","type":"journal-article","created":{"date-parts":[[2014,1,2]],"date-time":"2014-01-02T16:01:18Z","timestamp":1388678478000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A 2D graphical representation of the sequences of DNA based on triplets and its application"],"prefix":"10.1186","volume":"2014","author":[{"given":"Sai","family":"Zou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,1,2]]},"reference":[{"key":"42_CR1","first-page":"291","volume":"60","author":"W Chen","year":"2008","unstructured":"Chen W, Liao B, Liu Y, Zhu W, Su Z: A numerical representation of DNA sequences and its applications. 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