{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T22:59:24Z","timestamp":1774565964889,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["All Asth Clin Immun"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1186\/1710-1492-5-11","type":"journal-article","created":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T19:22:49Z","timestamp":1259695369000},"source":"Crossref","is-referenced-by-count":16,"title":["Importance of basophil activation testing in insect venom allergy"],"prefix":"10.1186","volume":"5","author":[{"given":"Mitja","family":"Kosnik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Korosec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,12,1]]},"reference":[{"key":"82_CR1","first-page":"100","volume":"18","author":"K M\u00fcnstedt","year":"2008","unstructured":"M\u00fcnstedt K, Hellner M, Winter D, von Georgi R: Allergy to bee venom in beekeepers in Germany. J Investig Allergol Clin Immunol. 2008, 18: 100-5.","journal-title":"J Investig Allergol Clin Immunol"},{"key":"82_CR2","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1111\/j.1365-2222.2008.03044.x","volume":"38","author":"L Diwakar","year":"2008","unstructured":"Diwakar L, Noorani S, Huissoon AP, Frew AJ, Krishna MT: Practice of venom immunotherapy in the United Kingdom: a national audit and review of literature. Clin Exp Allergy. 2008, 38: 1651-8. 10.1111\/j.1365-2222.2008.03044.x.","journal-title":"Clin Exp Allergy"},{"key":"82_CR3","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1159\/000024453","volume":"123","author":"F Straumann","year":"2000","unstructured":"Straumann F, Bucher C, W\u00fctrich B: Double sensitization to honeybee and wasp venom: immunotherapy with one or with both venoms? Value of FEIA inhibition for the identification of the cross-reacting IgE antibodies in double-sensitized patients to honeybee and wasp venom. Int Arch Allergy Immunol. 2000, 123: 268-74. 10.1159\/000024453.","journal-title":"Int Arch Allergy Immunol"},{"key":"82_CR4","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1159\/000234924","volume":"89","author":"JI Wypych","year":"1989","unstructured":"Wypych JI, Abeyounis CJ, Reisman RE: Analysis of differing patterns of cross-reactivity of honeybee and yellow jacket venom-specific IgE: use of purified venom fractions. Int Arch Allergy Appl Immunol. 1989, 89: 60-6. 10.1159\/000234924.","journal-title":"Int Arch Allergy Appl Immunol"},{"key":"82_CR5","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1067\/mai.2001.120013","volume":"108","author":"W Hemmer","year":"2001","unstructured":"Hemmer W, Focke M, Kolarich D, Wilson IB, Altmann F, Wohrl S, Gotz M, Jarisch R: Antibody binding to venom carbohydrates is a frequent cause for double positivity to honeybee and yellow jacket venom in patients with stinging-insect allergy. J Allergy Clin Immunol. 2001, 108: 1045-52. 10.1067\/mai.2001.120013.","journal-title":"J Allergy Clin Immunol"},{"key":"82_CR6","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1111\/j.1398-9995.2005.00960.x","volume":"60","author":"F Bonifazi","year":"2005","unstructured":"Bonifazi F, Jutel M, Bil\u00f3 BM, Birnbaum J, Muller U, EAACI Interest Group on Insect Venom Hypersensitivity: Prevention and treatment of hymenoptera venom allergy: guidelines for clinical practice. Allergy. 2005, 60: 1459-70. 10.1111\/j.1398-9995.2005.00960.x.","journal-title":"Allergy"},{"key":"82_CR7","first-page":"CR351","volume":"11","author":"M Modrzy\u0144ski","year":"2005","unstructured":"Modrzy\u0144ski M, Zawisza E: Possible induction of oral allergy syndrome during specific immunotherapy in patients sensitive to tree pollen. Med Sci Monit. 2005, 11: CR351-355.","journal-title":"Med Sci Monit"},{"key":"82_CR8","doi-asserted-by":"crossref","unstructured":"Juarez C, Blanca M, Miranda A, Fernandez J, Sanchez F, Carmona MJ, Avila MJ, Fernandez S, Fernandez J, Terrados S: Specific IgE antibodies to vespids in the course of immunotherpay with Vespula germanica administered to patients sensitized to Polistes dominulus. Allergy. 47: 299-302. 10.1111\/j.1398-9995.1992.tb02057.x.","DOI":"10.1111\/j.1398-9995.1992.tb02057.x"},{"key":"82_CR9","first-page":"183","volume":"77","author":"A Peternelj","year":"2008","unstructured":"Peternelj A, \u0160ilar M, Er\u017een R, Bajrovi\u010d N, Mu\u0161i\u010d E, Ko\u0161nik M, Koro\u0161ec P: Basophil activation test (BAT) in \u00bbin vitro\u00ab diagnosis of hymenoptera venom hypersensitivity. Zdravn Vest. 2008, 77: 183-7.","journal-title":"Zdravn Vest"},{"key":"82_CR10","first-page":"199","volume":"35","author":"L Antonicelli","year":"2003","unstructured":"Antonicelli L, Bil\u00f2 MB, Napoli G, Farabollini B, Bonifazi F: European hornet (Vespa crabro) sting: a new risk factor for life-threatening reaction in hymenoptera allergic patients?. Eur Ann Allergy Clin Immunol. 2003, 35: 199-203.","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"82_CR11","first-page":"25","volume":"43","author":"M Kosnik","year":"2002","unstructured":"Kosnik M, Korosec P, Silar M, Music E, Erzen R: Wasp venom is appropriate for immunotherapy of patients with allergic reaction to the European hornet sting. Croat Med J. 2002, 43: 25-7.","journal-title":"Croat Med J"},{"key":"82_CR12","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1034\/j.1398-9995.2000.00691.x","volume":"55","author":"M Kosnik","year":"2000","unstructured":"Kosnik M: Anaphylaxis to venom without IgE antibody. Allergy. 2000, 55: 676-7. 10.1034\/j.1398-9995.2000.00691.x.","journal-title":"Allergy"},{"key":"82_CR13","first-page":"31","volume":"16","author":"M Zidarn","year":"2007","unstructured":"Zidarn M, Kosnik M, Drinovec I: Anaphylaxis after Hymenoptera sting without detectable specific IgE. Acta Dermatovenerol Alp Panonica Adriat. 2007, 16: 31-3.","journal-title":"Acta Dermatovenerol Alp Panonica Adriat"},{"key":"82_CR14","first-page":"216","volume":"51","author":"F Ru\u00ebff","year":"1996","unstructured":"Ru\u00ebff F, Przybilla B, M\u00fcller U, Mosbech H: The sting challenge test in Hymenoptera venom allergy. Position paper of the Subcommittee on Insect Venom Allergy of the European Academy of Allergology and Clinical Immunology. Allergy. 1996, 51: 216-25.","journal-title":"Allergy"},{"key":"82_CR15","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/0140-6736(90)92272-J","volume":"336","author":"PW van der Linden","year":"1990","unstructured":"Linden van der PW, Hack CE, Kerckhaert JA, Struyvenberg A, Zwan van der JC: Preliminary report: complement activation in wasp-sting anaphylaxis. Lancet. 1990, 336: 904-6. 10.1016\/0140-6736(90)92272-J.","journal-title":"Lancet"},{"key":"82_CR16","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/370367a0","volume":"370","author":"TR Martin","year":"1994","unstructured":"Martin TR, Oettgen HC, Martin TR, Wynshaw-Boris A, Deng C, Drazen JM, Leder P: Active anaphylaxis in IgE-deficient mouse. Nature. 1994, 370: 367-10. 10.1038\/370367a0.","journal-title":"Nature"},{"key":"82_CR17","doi-asserted-by":"publisher","first-page":"1730","DOI":"10.1111\/j.1365-2222.2009.03347.x","volume":"39","author":"P Korosec","year":"2009","unstructured":"Korosec P, Erzen R, Silar M, Bajrovic N, Kopac P, Kosnik M: Basophil responsiveness in patients with insect sting allergies and negative venom-specific immunoglobulin E and skin prick test results. Clin Exp Allergy. 2009, 39: 1730-7. 10.1111\/j.1365-2222.2009.03347.x.","journal-title":"Clin Exp Allergy"},{"key":"82_CR18","first-page":"357","volume":"17","author":"DG Ebo","year":"2007","unstructured":"Ebo DG, Hagendorens MM, Bridts CH, De Clerck LS, Stevens WJ: Hymenoptera venom allergy: taking the sting out of difficult cases. J Investig Allergol Clin Immunol. 2007, 17: 357-360.","journal-title":"J Investig Allergol Clin Immunol"},{"key":"82_CR19","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1111\/j.1398-9995.2004.00624.x","volume":"59","author":"SM Erdmann","year":"2004","unstructured":"Erdmann SM, Sachs B, Kwiecien R, Moll-Slodowy S, Sauer I, Merk HF: The basophil activation test in wasp venom allergy: sensitivity, specifi city and monitoring specifi c immunotherapy. Allergy. 2004, 59: 1102-9. 10.1111\/j.1398-9995.2004.00624.x.","journal-title":"Allergy"},{"key":"82_CR20","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1034\/j.1398-9995.2000.00587.x","volume":"55","author":"H Mosbech","year":"2000","unstructured":"Mosbech H, Mueller U: Side-effects of insect venom immunotherapy: results from an EAACI multicenter study. European Academy of Allergology and Clinical Immunology. Allergy. 2000, 55: 1005-1010. 10.1034\/j.1398-9995.2000.00587.x.","journal-title":"Allergy"},{"key":"82_CR21","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1159\/000142048","volume":"147","author":"L Gorska","year":"2008","unstructured":"Gorska L, Chelminska M, Kuziemski K, Skrzypski M, Niedoszytko M, Damps-Konstanska I, Szymanowska A, Siemi\u00f1ska A, Wajda B, Drozdowska A, Jutel M, Jassem E: Analysis of safety, risk factors and pretreatment methods during rush hymenoptera venom immunotherapy. Int Arch Allergy Immunol. 2008, 147: 241-5. 10.1159\/000142048.","journal-title":"Int Arch Allergy Immunol"},{"key":"82_CR22","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1111\/j.1398-9995.2005.00894.x","volume":"60","author":"M Kosnik","year":"2005","unstructured":"Kosnik M, Silar M, Bajrovic N, Music E, Korosec P: High sensitivity of basophils predicts side-effects in venom immunotherapy. Allergy. 2005, 60: 1401-6. 10.1111\/j.1398-9995.2005.00894.x.","journal-title":"Allergy"},{"issue":"Suppl 88","key":"82_CR23","first-page":"642","volume":"63","author":"S Zitnik","year":"2008","unstructured":"Zitnik S, Glavnik V, Avcin T, Accetto M, Toplak N, Silar M, Korosec P: High sensitivity of basophils predict side effect in bee venom immunotherapy in children. Allergy. 2008, 63 (Suppl 88): 642-","journal-title":"Allergy"},{"key":"82_CR24","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1056\/NEJM197807272990401","volume":"299","author":"KJ Hunt","year":"1978","unstructured":"Hunt KJ, Valentine MD, Sobotka AK, Benton AW, Amodio FJ, Lichtenstein LM: A controlled trial of immunotherapy in insect hypersensitivity. N Engl J Med. 1978, 299: 157-61. 10.1056\/NEJM197807272990401.","journal-title":"N Engl J Med"},{"key":"82_CR25","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1067\/mai.2002.125827","volume":"110","author":"NG Joanne","year":"2002","unstructured":"Joanne NG, Elberink O, Monchy JGR, Heide van der S, Guyatt GH, Dubois AEJ: Venom immunotherapy improves health related quality of life in patients allergic to yellow jacket venom. J Allergy Clin Immunol. 2002, 110: 174-82. 10.1067\/mai.2002.125827.","journal-title":"J Allergy Clin Immunol"},{"key":"82_CR26","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/j.1610-0387.2007.06579.x","volume":"6","author":"A Roesch","year":"2008","unstructured":"Roesch A, Boerzsoenyi J, Babilas P, Landthaler M, Szeimies RM: Outcome survey of insect venom allergic patients with venom immunotherapy in a rural population. J Dtsch Dermatol Ges. 2008, 6: 292-7. 10.1111\/j.1610-0387.2007.06579.x.","journal-title":"J Dtsch Dermatol Ges"},{"key":"82_CR27","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/S0091-6749(98)70167-8","volume":"101","author":"E Lerch","year":"1998","unstructured":"Lerch E, M\u00fcller UR: Long-term protection after stopping venom immunotherapy: results of re-stings in 200 patients. J Allergy Clin Immunol. 1998, 101: 606-12. 10.1016\/S0091-6749(98)70167-8.","journal-title":"J Allergy Clin Immunol"},{"key":"82_CR28","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1067\/mai.2001.114985","volume":"107","author":"WC Light","year":"2001","unstructured":"Light WC: Insect sting fatality 9 years after venom treatment. J Allergy Clin Immunol. 2001, 107: 925-10.1067\/mai.2001.114985.","journal-title":"J Allergy Clin Immunol"},{"key":"82_CR29","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/S1081-1206(10)60425-5","volume":"100","author":"T Hafner","year":"2008","unstructured":"Hafner T, DuBuske L, Kosnik M: Long-term efficacy of venom immunotherapy. Ann Allergy Asthma Immunol. 2008, 100: 162-5. 10.1016\/S1081-1206(10)60425-5.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"82_CR30","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1159\/000116361","volume":"146","author":"A Peternelj","year":"2008","unstructured":"Peternelj A, Silar M, Erzen R, Kosnik M, Korosec P: Basophil sensitivity in patients not responding to venom immunotherapy. Int Arch Allergy Immunol. 2008, 146: 248-254. 10.1159\/000116361.","journal-title":"Int Arch Allergy Immunol"}],"container-title":["Allergy, Asthma &amp; Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1710-1492-5-11.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1710-1492-5-11\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1710-1492-5-11.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T04:50:55Z","timestamp":1558673455000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacijournal.biomedcentral.com\/articles\/10.1186\/1710-1492-5-11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["82"],"URL":"https:\/\/doi.org\/10.1186\/1710-1492-5-11","relation":{},"ISSN":["1710-1492"],"issn-type":[{"value":"1710-1492","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]},"article-number":"11"}}