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To test whether Wnt6 also contributes towards wing size regulation, we generated Wnt6 knockout flies.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Wnt6 knockout flies are viable and have no obvious defect in wing size or planar cell polarity. Surprisingly, Wnt6 knockouts lack maxillary palps. Interestingly, Wnt6 is absent from the genome of hemipterans, correlating with the absence of maxillary palps in these insects.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Wnt6 is important for maxillary palp development in <jats:italic>Drosophila<\/jats:italic>, and phylogenetic analysis indicates that loss of Wnt6 may also have led to loss of maxillary palps on an evolutionary time scale.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1741-7007-11-104","type":"journal-article","created":{"date-parts":[[2013,10,3]],"date-time":"2013-10-03T15:01:04Z","timestamp":1380812464000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Wnt6 is required for maxillary palp formation in Drosophila"],"prefix":"10.1186","volume":"11","author":[{"given":"Nikolaos","family":"Doumpas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1sp\u00e1r","family":"J\u00e9kely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelio A","family":"Teleman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,10,3]]},"reference":[{"key":"724_CR1","doi-asserted-by":"publisher","first-page":"76","DOI":"10.4161\/org.6.2.10375","volume":"6","author":"AW Shingleton","year":"2010","unstructured":"Shingleton AW: The regulation of organ size in Drosophila: physiology, plasticity, patterning and physical force. 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