{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T12:14:04Z","timestamp":1775909644449,"version":"3.50.1"},"reference-count":110,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,11,14]],"date-time":"2007-11-14T00:00:00Z","timestamp":1194998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Med"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1741-7015-5-32","type":"journal-article","created":{"date-parts":[[2007,11,14]],"date-time":"2007-11-14T19:12:54Z","timestamp":1195067574000},"source":"Crossref","is-referenced-by-count":118,"title":["A meta-analysis of N-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity"],"prefix":"10.1186","volume":"5","author":[{"given":"Denise A","family":"Gonzales","sequence":"first","affiliation":[]},{"given":"Kelly J","family":"Norsworthy","sequence":"additional","affiliation":[]},{"given":"Steven J","family":"Kern","sequence":"additional","affiliation":[]},{"given":"Steve","family":"Banks","sequence":"additional","affiliation":[]},{"given":"Pamela C","family":"Sieving","sequence":"additional","affiliation":[]},{"given":"Robert A","family":"Star","sequence":"additional","affiliation":[]},{"given":"Charles","family":"Natanson","sequence":"additional","affiliation":[]},{"given":"Robert L","family":"Danner","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2007,11,14]]},"reference":[{"key":"133_CR1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1136\/bmj.316.7126.221","volume":"316","author":"GD Smith","year":"1998","unstructured":"Smith GD, Egger M: Meta-analysis: unresolved issues and future developments. Br Med J. 1998, 316: 221-225.","journal-title":"Br Med J"},{"key":"133_CR2","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.1016\/S0140-6736(99)04149-5","volume":"354","author":"D Moher","year":"1999","unstructured":"Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF: Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet. 1999, 354: 1896-1900. 10.1016\/S0140-6736(99)04149-5.","journal-title":"Lancet"},{"key":"133_CR3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.lab.2005.08.006","volume":"147","author":"JH Noble Jr","year":"2006","unstructured":"Noble JH: Meta-analysis: methods, strengths, weaknesses, and political uses. J Lab Clin Med. 2006, 147: 7-20. 10.1016\/j.lab.2005.08.006.","journal-title":"J Lab Clin Med"},{"key":"133_CR4","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","volume":"21","author":"JP Higgins","year":"2002","unstructured":"Higgins JP, Thompson SG: Quantifying heterogeneity in a meta-analysis. Stat Med. 2002, 21: 1539-1558. 10.1002\/sim.1186.","journal-title":"Stat Med"},{"key":"133_CR5","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Davey Smith G, Schneider M, Minder C: Bias in meta-analysis detected by a simple, graphical test. Br Med J. 1997, 315: 629-634.","journal-title":"Br Med J"},{"key":"133_CR6","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.2307\/2533446","volume":"50","author":"CB Begg","year":"1994","unstructured":"Begg CB, Mazumdar M: Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994, 50: 1088-1101. 10.2307\/2533446.","journal-title":"Biometrics"},{"key":"133_CR7","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/0140-6736(91)90201-Y","volume":"337","author":"PJ Easterbrook","year":"1991","unstructured":"Easterbrook PJ, Berlin JA, Gopalan R, Matthews DR: Publication bias in clinical research. Lancet. 1991, 337: 867-872. 10.1016\/0140-6736(91)90201-Y.","journal-title":"Lancet"},{"key":"133_CR8","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/bmj.311.7007.753c","volume":"311","author":"M Egger","year":"1995","unstructured":"Egger M, Smith GD: Misleading meta-analysis. Br Med J. 1995, 311: 753-754.","journal-title":"Br Med J"},{"key":"133_CR9","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1056\/NEJM199708213370806","volume":"337","author":"J LeLorier","year":"1997","unstructured":"LeLorier J, Gregoire G, Benhaddad A, Lapierre J, Derderian F: Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med. 1997, 337: 536-542. 10.1056\/NEJM199708213370806.","journal-title":"N Engl J Med"},{"key":"133_CR10","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1056\/NEJM200007203430304","volume":"343","author":"M Tepel","year":"2000","unstructured":"Tepel M, van der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W: Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. N Engl J Med. 2000, 343: 180-184. 10.1056\/NEJM200007203430304.","journal-title":"N Engl J Med"},{"key":"133_CR11","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/S0002-9149(01)02243-3","volume":"89","author":"LJ Diaz-Sandoval","year":"2002","unstructured":"Diaz-Sandoval LJ, Kosowsky BD, Losordo DW: Acetylcysteine to prevent angiography-related renal tissue injury (the APART trial). Am J Cardiol. 2002, 89: 356-358. 10.1016\/S0002-9149(01)02243-3.","journal-title":"Am J Cardiol"},{"key":"133_CR12","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/S0735-1097(02)01958-7","volume":"40","author":"C Briguori","year":"2002","unstructured":"Briguori C, Manganelli F, Scarpato P, Elia PP, Golia B, Riviezzo G, Lepore S, Librera M, Villari B, Colombo A, Ricciardelli B: Acetylcysteine and contrast agent-associated nephrotoxicity. J Am Coll Cardiol. 2002, 40: 298-303. 10.1016\/S0735-1097(02)01958-7.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR13","first-page":"529","volume":"19","author":"A Vallero","year":"2002","unstructured":"Vallero A, Cesano G, Pozzato M, Garbo R, Minelli M, Quarello F, Formica M: Nefropatia da contrasto in cardiologia interventistica: assenza di vantaggi con impiego profilattico di N-Acetilcisteina. G Ital Nefrol. 2002, 19: 529-533.","journal-title":"G Ital Nefrol"},{"key":"133_CR14","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1016\/S0735-1097(02)02308-2","volume":"40","author":"KG Shyu","year":"2002","unstructured":"Shyu KG, Cheng JJ, Kuan P: Acetylcysteine protects against acute renal damage in patients with abnormal renal function undergoing a coronary procedure. J Am Coll Cardiol. 2002, 40: 1383-1388. 10.1016\/S0735-1097(02)02308-2.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR15","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1002\/ccd.10323","volume":"57","author":"S Allaqaband","year":"2002","unstructured":"Allaqaband S, Tumuluri R, Malik AM, Gupta A, Volkert P, Shalev Y, Bajwa TK: Prospective randomized study of N-acetylcysteine, fenoldopam, and saline for prevention of radiocontrast-induced nephropathy. Catheter Cardiovasc Interv. 2002, 57: 279-283. 10.1002\/ccd.10323.","journal-title":"Catheter Cardiovasc Interv"},{"key":"133_CR16","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1046\/j.1523-1755.2002.00673.x","volume":"62","author":"JD Durham","year":"2002","unstructured":"Durham JD, Caputo C, Dokko J, Zaharakis T, Pahlavan M, Keltz J, Dutka P, Marzo K, Maesaka JK, Fishbane S: A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography. Kidney Int. 2002, 62: 2202-2207. 10.1046\/j.1523-1755.2002.00673.x.","journal-title":"Kidney Int"},{"key":"133_CR17","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1001\/jama.289.5.553","volume":"289","author":"J Kay","year":"2003","unstructured":"Kay J, Chow WH, Chan TM, Lo SK, Kwok OH, Yip A, Fan K, Lee CH, Lam WF: Acetylcysteine for prevention of acute deterioration of renal function following elective coronary angiography and intervention: a randomized controlled trial. JAMA. 2003, 289: 553-558. 10.1001\/jama.289.5.553.","journal-title":"JAMA"},{"key":"133_CR18","doi-asserted-by":"publisher","first-page":"327A","DOI":"10.1016\/S0735-1097(03)81986-1","volume":"41","author":"E Loutrianakis","year":"2003","unstructured":"Loutrianakis E, Stella D, Hussain A, Lewis B, Steen L, Sochanski M, Leya F, Grassman E: Randomized comparison of fenoldopam and N-acetylcysteine to saline in the prevention of radio-contrast induced nephropathy. J Am Coll Cardiol. 2003, 41: 327A-10.1016\/S0735-1097(03)81986-1.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR19","first-page":"7","volume":"81","author":"A Azmus","year":"2003","unstructured":"Azmus A, Manica A, Manica JL, Duro K, Bulcao L, Lima C, Frey M, Gottschall C: Efeito da acetilcisteina sobre a funcao renal de pacientes sumetidos a cateterismo cardiaco \u2013 resultados finais. Arq Bras Cardiol. 2003, 81: 7.","journal-title":"Arq Bras Cardiol"},{"key":"133_CR20","first-page":"IV","volume":"108","author":"VO Gomes","year":"2003","unstructured":"Gomes VO, Caramori P, Lasevitch R, Brizolara AA, Nery P, Araujo A, Hemesath M, Brito FS: Prevention of contrast-induced nephropathy with N-acetylcysteine in patients undergoing coronary angiography: a randomized multicenter trial. Circulation. 2003, 108: IV-460.","journal-title":"Circulation"},{"key":"133_CR21","first-page":"IV","volume":"108","author":"P Nguyen-Ho","year":"2003","unstructured":"Nguyen-Ho P, Dzavik V, Seidelin P, Daly P, Ross J, McLaughlin P, Ing D, Barolet A, Schwartz L, Miner SE: N-acetylcysteine does not prevent long-term clinical events despite reducing periprocedural contrast-associated nephropathy. Circulation. 2003, 108: IV-445.","journal-title":"Circulation"},{"key":"133_CR22","doi-asserted-by":"publisher","first-page":"2182","DOI":"10.1046\/j.1523-1755.2003.00322.x","volume":"64","author":"S Efrati","year":"2003","unstructured":"Efrati S, Dishy V, Averbukh M, Blatt A, Krakover R, Weisgarten J, Morrow JD, Stein MC, Golik A: The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography. Kidney Int. 2003, 64: 2182-2187. 10.1046\/j.1523-1755.2003.00322.x.","journal-title":"Kidney Int"},{"key":"133_CR23","first-page":"1157","volume":"96","author":"R El Mahmoud","year":"2003","unstructured":"El Mahmoud R, Le Feuvre C, Le Quan Sang KH, Helft G, Beygui F, Batisse JP, Metzger JP: Absence of nephro-protective effect of acetylcysteine in patients with chronic renal failure investigated by coronary angiography. Arch Mal Coeur Vaiss. 2003, 96: 1157-1161.","journal-title":"Arch Mal Coeur Vaiss"},{"key":"133_CR24","doi-asserted-by":"publisher","first-page":"555","DOI":"10.2143\/AC.58.6.2005321","volume":"58","author":"JM Kefer","year":"2003","unstructured":"Kefer JM, Hanet CE, Boitte S, Wilmotte L, De Kock M: Acetylcysteine, coronary procedure and prevention of contrast-induced worsening of renal function: which benefit for which patient?. Acta Cardiol. 2003, 58: 555-560. 10.2143\/AC.58.6.2005321.","journal-title":"Acta Cardiol"},{"key":"133_CR25","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1002\/ccd.10684","volume":"60","author":"BD MacNeill","year":"2003","unstructured":"MacNeill BD, Harding SA, Bazari H, Patton KK, Colon-Hernadez P, DeJoseph D, Jang IK: Prophylaxis of contrast-induced nephropathy in patients undergoing coronary angiography. Catheter Cardiovasc Interv. 2003, 60: 458-461. 10.1002\/ccd.10684.","journal-title":"Catheter Cardiovasc Interv"},{"key":"133_CR26","doi-asserted-by":"publisher","first-page":"E23","DOI":"10.1016\/S0002-8703(03)00511-8","volume":"146","author":"JB Oldemeyer","year":"2003","unstructured":"Oldemeyer JB, Biddle WP, Wurdeman RL, Mooss AN, Cichowski E, Hilleman DE: Acetylcysteine in the prevention of contrast-induced nephropathy after coronary angiography. Am Heart J. 2003, 146: E23-10.1016\/S0002-8703(03)00511-8.","journal-title":"Am Heart J"},{"key":"133_CR27","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.ehj.2003.11.011","volume":"25","author":"I Goldenberg","year":"2004","unstructured":"Goldenberg I, Shechter M, Matetzky S, Jonas M, Adam M, Pres H, Elian D, Agranat O, Schwammenthal E, Guetta V: Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography. A randomized controlled trial and review of the current literature. Eur Heart J. 2004, 25: 212-218. 10.1016\/j.ehj.2003.11.011.","journal-title":"Eur Heart J"},{"key":"133_CR28","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1159\/000077294","volume":"4","author":"M Agrawal","year":"2004","unstructured":"Agrawal M, Wodlinger AM, Huggins CE, Tudor GE, Pieper JA, O'Reilly KP, Denu-Ciocca CJ, Stouffer GA, Ohman EM: Effect of N-acetylcysteine on serum creatinine concentration in patients with chronic renal insufficiency who are undergoing coronary angiography. Heart Drug. 2004, 4: 87-91. 10.1159\/000077294.","journal-title":"Heart Drug"},{"key":"133_CR29","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1053\/j.ajkd.2004.01.010","volume":"43","author":"JW Fung","year":"2004","unstructured":"Fung JW, Szeto CC, Chan WW, Kum LC, Chan AK, Wong JT, Wu EB, Yip GW, Chan JY, Yu CM, Woo KS, Sanderson JE: Effect of N-acetylcysteine for prevention of contrast nephropathy in patients with moderate to severe renal insufficiency: a randomized trial. Am J Kidney Dis. 2004, 43: 801-808. 10.1053\/j.ajkd.2004.01.010.","journal-title":"Am J Kidney Dis"},{"key":"133_CR30","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1111\/j.1540-8183.2004.09880.x","volume":"17","author":"A Ochoa","year":"2004","unstructured":"Ochoa A, Pellizzon G, Addala S, Grines C, Isayenko Y, Boura J, Rempinski D, O'Neill W, Kahn J: Abbreviated dosing of N-acetylcysteine prevents contrast-induced nephropathy after elective and urgent coronary angiography and intervention. J Interv Cardiol. 2004, 17: 159-165. 10.1111\/j.1540-8183.2004.09880.x.","journal-title":"J Interv Cardiol"},{"key":"133_CR31","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.ahj.2004.03.041","volume":"148","author":"JG Webb","year":"2004","unstructured":"Webb JG, Pate GE, Humphries KH, Buller CE, Shalansky S, Al Shamari A, Sutander A, Williams T, Fox RS, Levin A: A randomized controlled trial of intravenous N-acetylcysteine for the prevention of contrast-induced nephropathy after cardiac catheterization: lack of effect. Am Heart J. 2004, 148: 422-429. 10.1016\/j.ahj.2004.03.041.","journal-title":"Am Heart J"},{"key":"133_CR32","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1093\/ajhp\/60.21.2232","volume":"60","author":"Q Raven","year":"2003","unstructured":"Raven Q, Walton T, Howe A, Macon E: Role of acetylcysteine in the prevention of contrast-media-induced nephrotoxicity. Am J Health Syst Pharm. 2003, 60: 2232-2235.","journal-title":"Am J Health Syst Pharm"},{"key":"133_CR33","doi-asserted-by":"publisher","first-page":"255A","DOI":"10.1016\/S0895-7061(03)00770-2","volume":"16","author":"DY Pai","year":"2003","unstructured":"Pai DY, Denny DF, Shanahan AJ, Ruddy MC: The effect of acetylcysteine on renal function in elderly high-risk patients exposed to arteriographic contrast dye. Am J Hypertens. 2003, 16: 255A-10.1016\/S0895-7061(03)00770-2.","journal-title":"Am J Hypertens"},{"key":"133_CR34","doi-asserted-by":"publisher","first-page":"S131","DOI":"10.1016\/j.cardfail.2004.06.423","volume":"10","author":"D Nicholson","year":"2004","unstructured":"Nicholson D, Haas GJ, Carnes CA, Abraham WT, Feldman DS: Lack of efficacy of N-acetylcysteine in attenuating contrast induced nephropathy in patients with severe systolic heart failure. J Card Fail. 2004, 10: S131-10.1016\/j.cardfail.2004.06.423.","journal-title":"J Card Fail"},{"key":"133_CR35","first-page":"A16","volume":"39","author":"CW Erickson","year":"2002","unstructured":"Erickson CW, Erickson JE, Wilsker G, Brunner L: A retrospective analysis of oral acetylcysteine intervention to prevent radiographic contrast-induced nephropathy in patients undergoing coronary angiography with elevated serum creatinine. Am J Kidney Dis. 2002, 39: A16.","journal-title":"Am J Kidney Dis"},{"key":"133_CR36","doi-asserted-by":"publisher","first-page":"H144","DOI":"10.1016\/S0002-9149(02)02437-2","volume":"90","author":"M Adamian","year":"2002","unstructured":"Adamian M, Mehran R, Moussa I, Dangas G, Mintz GS, Lansky AJ, Adamyan Y, Ibrahim M, Fahy M, Cioara C, et al: Mucomyst administration in percutaneous coronary interventions in patients with impaired renal function: a matched comparison. Am J Cardiol. 2002, 90: H144-10.1016\/S0002-9149(02)02437-2.","journal-title":"Am J Cardiol"},{"key":"133_CR37","first-page":"A108","volume":"31","author":"S Rasty","year":"2003","unstructured":"Rasty S, Sierra M, Salmon A: N-acetylcysteine versus N-acetylcysteine plus fenoldopam in the prevention of contrast induce nephropathy. Crit Care Med. 2003, 31: A108.","journal-title":"Crit Care Med"},{"key":"133_CR38","first-page":"38","volume":"103","author":"SH Rezkalla","year":"2004","unstructured":"Rezkalla SH, Benz M: Effectiveness of acetylcysteine on preventing renal dysfunction in patients undergoing coronary procedures. Wis Med J. 2004, 103: 38-41.","journal-title":"Wis Med J"},{"key":"133_CR39","doi-asserted-by":"publisher","first-page":"63A","DOI":"10.1016\/S0735-1097(03)80887-2","volume":"41","author":"AS Kanderian","year":"2003","unstructured":"Kanderian AS, Abdelhadi RH, Bhatt DL, Schneider J, Chung MK: Hydration versus N-acetylcysteine for protection of renal function in patients with renal insufficiency undergoing percutaneous coronary intervention. J Am Coll Cardiol. 2003, 41: 63A-10.1016\/S0735-1097(03)80887-2.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR40","doi-asserted-by":"publisher","first-page":"23A","DOI":"10.1016\/S0735-1097(03)80100-6","volume":"41","author":"NK Gill","year":"2003","unstructured":"Gill NK, Piccione EA, Vido D, Clark BA, Shannon RP: The role of acetylcysteine in preventing contrast-induced nephropathy following cardiac catheterization in patients with acute and chronic renal failure. J Am Coll Cardiol. 2003, 41: 23A-10.1016\/S0735-1097(03)80100-6.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR41","first-page":"H143","volume":"90","author":"PJ Casterella","year":"2002","unstructured":"Casterella PJ, Mason SM, Doing T, Burke JL, Revenaugh JR, Sorensen SG, Horne BD, Pearson RR, Anderson JL, Muhlstein JB: N-acetylcysteine and fenoldopam do not significantly reduce the incidence of contrast-induced nephropathy. Am J Cardiol. 2002, 90: H143.","journal-title":"Am J Cardiol"},{"key":"133_CR42","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1002\/ccd.10389","volume":"58","author":"F Boccalandro","year":"2003","unstructured":"Boccalandro F, Amhad M, Smalling RW, Sdringola S: Oral acetylcysteine does not protect renal function from moderate to high doses of intravenous radiographic contrast. Catheter Cardiovasc Interv. 2003, 58: 336-341. 10.1002\/ccd.10389.","journal-title":"Catheter Cardiovasc Interv"},{"key":"133_CR43","first-page":"311","volume":"15","author":"GM Tadros","year":"2003","unstructured":"Tadros GM, Mouhayar EN, Akinwande AO, Campbell B, Wood C, Blankenship JA: Prevention of radiocontrast-induced nephropathy with N-acetylcysteine in patients undergoing coronary angiography. J Invasive Cardiol. 2003, 15: 311-314.","journal-title":"J Invasive Cardiol"},{"key":"133_CR44","doi-asserted-by":"publisher","first-page":"62A","DOI":"10.1016\/S0735-1097(03)80883-5","volume":"41","author":"GJ Nogareda","year":"2003","unstructured":"Nogareda GJ, Ricci DR, Penn IM, Huckell V, Fox R, Chow J, Eichman A, Buller CE: Oral N-acetylcysteine administered immediately prior to routine percutaneous coronary procedures ameliorates contrast-induced nephrotoxicity. J Am Coll Cardiol. 2003, 41: 62A-63A. 10.1016\/S0735-1097(03)80883-5.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR45","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.ehj.2003.11.016","volume":"25","author":"C Briguori","year":"2004","unstructured":"Briguori C, Colombo A, Violante A, Balestrieri P, Manganelli F, Paolo Elia P, Golia B, Lepore S, Riviezzo G, Scarpato P, et al: Standard vs double dose of N-acetylcysteine to prevent contrast agent associated nephrotoxicity. Eur Heart J. 2004, 25: 206-211. 10.1016\/j.ehj.2003.11.016.","journal-title":"Eur Heart J"},{"key":"133_CR46","first-page":"447A","volume":"13","author":"BD Bader","year":"2002","unstructured":"Bader BD, Berger ED, Rossmann S, Risler T, Erley CM: Prevention of contrast media-induced acute renal failure in patients with severe impaired renal function \u2013 theophylline versus N-acetylcysteine. J Am Soc Nephrol. 2002, 13: 447A.","journal-title":"J Am Soc Nephrol"},{"key":"133_CR47","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.jacc.2004.04.052","volume":"44","author":"C Briguori","year":"2004","unstructured":"Briguori C, Colombo A, Airoldi F, Violante A, Castelli A, Balestrieri P, Paolo Elia P, Golia B, Lepore S, Riviezzo G, et al: N-acetylcysteine versus fenoldopam mesylate to prevent contrast agent-associated nephrotoxicity. J Am Coll Cardiol. 2004, 44: 762-765. 10.1016\/j.jacc.2004.04.052.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR48","doi-asserted-by":"publisher","first-page":"S139","DOI":"10.1007\/s00134-001-1194-1","volume":"28","author":"W Huber","year":"2002","unstructured":"Huber W, Eckel F, Saur D, Sennefelder A, Hennico R, Schenk C, Schmelz R, Fritsch R, Weiss W, Classen M, Heemann U: Prophylaxis of contrast-induced nephropathy: acetylcysteine, theophylline or both \u2013 a randomized study. Intensive Care Medicine. 2002, 28: S139-10.1007\/s00134-001-1194-1.","journal-title":"Intensive Care Medicine"},{"key":"133_CR49","doi-asserted-by":"publisher","first-page":"176E","DOI":"10.1016\/j.amjcard.2004.03.068","volume":"94","author":"F Pelliccia","year":"2004","unstructured":"Pelliccia F, Pristipino C, Pasceri V, Granatelli A, Speciale G, Roncella A, Richichi G: A pilot randomized study on the safety and efficacy of the association fenoldopam-acetylcysteine for preventing contrast-induced renal failure. Am J Cardiol. 2004, 94: 176E-177E. 10.1016\/j.amjcard.2004.03.068.","journal-title":"Am J Cardiol"},{"key":"133_CR50","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1093\/ndt\/gfh261","volume":"19","author":"LF Drager","year":"2004","unstructured":"Drager LF, Andrade L, Barros de Toledo JF, Laurindo FR, Machado Cesar LA, Seguro AC: Renal effects of N-acetylcysteine in patients at risk for contrast nephropathy: decrease in oxidant stress-mediated renal tubular injury. Nephrol Dial Transplant. 2004, 19: 1803-1807. 10.1093\/ndt\/gfh261.","journal-title":"Nephrol Dial Transplant"},{"key":"133_CR51","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1002\/bjs.4686","volume":"91","author":"ST Rashid","year":"2004","unstructured":"Rashid ST, Salman M, Myint F, Baker D, Agarwal S, Hamilton G: N-Acetylcysteine for the prevention of nephropathy induced by radiographic contrast media in vascular patients undergoing angiography: a randomised, double-blind, controlled trial. Br J Surg. 2004, 91: 139-10.1002\/bjs.4686.","journal-title":"Br J Surg"},{"key":"133_CR52","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1093\/ndt\/gfg140","volume":"18","author":"DS Ray","year":"2003","unstructured":"Ray DS, Srinivas V: Role of N-acetyl cysteine in prevention of contrast nephropathy in patients of diabetic renal failure: a prospective study. Nephrol Dial Transplant. 2003, 18: 664-10.1093\/ndt\/gfg140.","journal-title":"Nephrol Dial Transplant"},{"key":"133_CR53","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1161\/01.CIR.0000023625.12626.29","volume":"106","author":"JPS Kahlon","year":"2002","unstructured":"Kahlon JPS, Moser L, Rosman H, Nordstrom C, Zafar A, Khairullah Q, Schreiber T, LaLonde T, Gardin J, Yamasaki H: Effectiveness of N-acetylcysteine for the prevention of radiocontrast-induced nephropathy: is the jury still out?. Circulation. 2002, 106: 691-692. 10.1161\/01.CIR.0000023625.12626.29.","journal-title":"Circulation"},{"key":"133_CR54","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1016\/S0735-1097(03)00487-X","volume":"41","author":"CS Baker","year":"2003","unstructured":"Baker CS, Wragg A, Kumar S, De Palma R, Baker LR, Knight CJ: A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study. J Am Coll Cardiol. 2003, 41: 2114-2118. 10.1016\/S0735-1097(03)00487-X.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR55","first-page":"80","volume":"17","author":"AD Azmus","year":"2005","unstructured":"Azmus AD, Gottschall C, Manica A, Manica J, Duro K, Frey M, Bulcao L, Lima C: Effectiveness of acetylcysteine in prevention of contrast nephropathy. J Invasive Cardiol. 2005, 17: 80-84.","journal-title":"J Invasive Cardiol"},{"key":"133_CR56","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1136\/hrt.2004.039636","volume":"91","author":"VO Gomes","year":"2005","unstructured":"Gomes VO, Poli de Figueredo CE, Caramori P, Lasevitch R, Bodanese LC, Araujo A, Roedel AP, Caramori AP, Brito FS, Bezerra HG, et al: N-acetylcysteine does not prevent contrast induced nephropathy after cardiac catheterisation with an ionic low osmolality contrast medium: a multicentre clinical trial. Heart. 2005, 91: 774-778. 10.1136\/hrt.2004.039636.","journal-title":"Heart"},{"key":"133_CR57","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.ahj.2004.05.015","volume":"148","author":"SE Miner","year":"2004","unstructured":"Miner SE, Dzavik V, Nguyen-Ho P, Richardson R, Mitchell J, Atchison D, Seidelin P, Daly P, Ross J, McLaughlin PR, et al: N-acetylcysteine reduces contrast-associated nephropathy but not clinical events during long-term follow-up. Am Heart J. 2004, 148: 690-695. 10.1016\/j.ahj.2004.05.015.","journal-title":"Am Heart J"},{"key":"133_CR58","doi-asserted-by":"crossref","first-page":"13","DOI":"10.31053\/1853.0605.v61.n1.32593","volume":"61","author":"D Balderramo","year":"2004","unstructured":"Balderramo D, Verdu M, Ramacciotti C, Cremona L, Lemos P, Orias M, Eduardo MJ: Renoprotective effect of high periprocedural doses of oral N-acetylcysteine in patients scheduled to undergo a same-day angiography. Rev Fac Cien Med Univ Nac Corboda. 2004, 61: 13-19.","journal-title":"Rev Fac Cien Med Univ Nac Corboda"},{"key":"133_CR59","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1097\/01.fjc.0000176730.59443.dd","volume":"46","author":"O Gulel","year":"2005","unstructured":"Gulel O, Keles T, Eraslan H, Aydogdu S, Diker E, Ulusoy V: Prophylactic acetylcysteine usage for prevention of contrast nephropathy after coronary angiography. J Cardiovasc Pharmacol. 2005, 46: 464-467. 10.1097\/01.fjc.0000176730.59443.dd.","journal-title":"J Cardiovasc Pharmacol"},{"key":"133_CR60","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.hlc.2005.06.007","volume":"14","author":"E Kotlyar","year":"2005","unstructured":"Kotlyar E, Keogh A, Thavapalachandran S, Allada C, Sharp J, Dias L, Muller D: Prehydration alone is sufficient to prevent contrast-induced nephropathy after day-only angiography procedures \u2013 a randomised controlled trial. Heart Lung Circ. 2005, 14: 245-251. 10.1016\/j.hlc.2005.06.007.","journal-title":"Heart Lung Circ"},{"key":"133_CR61","doi-asserted-by":"publisher","first-page":"1032.e1039","DOI":"10.1016\/j.ahj.2006.02.002","volume":"151","author":"L Coyle","year":"2006","unstructured":"Coyle L, Rodriguez A, Jeschke R, Simon-Lee A, Abbott K, Taylor A: Acetylcysteine In Diabetes (AID): a randomized study of acetylcysteine for the prevention of contrast nephropathy in diabetics. Am Heart J. 2006, 151: 1032.e1039-e1012. 10.1016\/j.ahj.2006.02.002.","journal-title":"Am Heart J"},{"key":"133_CR62","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1007\/s00270-005-0127-8","volume":"29","author":"C Sandhu","year":"2006","unstructured":"Sandhu C, Belli A, Oliveira D: The role of N-acetylcysteine in the prevention of contrast-induced nephrotoxicity. Cardiovasc Intervent Radiol. 2006, 29: 344-347. 10.1007\/s00270-005-0127-8.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"133_CR63","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ijcard.2006.04.023","volume":"115","author":"N Carbonell","year":"2007","unstructured":"Carbonell N, Blasco M, Sanjuan R, Perez-Sancho E, Sanchis J, Insa L, Bodi V, Nunez J, Garcia-Ramon R, Miguel A: Intravenous N-acetylcysteine for preventing contrast-induced nephropathy: a randomised trial. Int J Cardiol. 2007, 115: 57-62. 10.1016\/j.ijcard.2006.04.023.","journal-title":"Int J Cardiol"},{"key":"133_CR64","doi-asserted-by":"publisher","first-page":"2773","DOI":"10.1056\/NEJMoa054209","volume":"354","author":"G Marenzi","year":"2006","unstructured":"Marenzi G, Assanelli E, Marana I, Lauri G, Campodonico J, Grazi M, De Metrio M, Galli S, Fabbiocchi F, Montorsi P, et al: N-acetylcysteine and contrast-induced nephropathy in primary angioplasty. N Engl J Med. 2006, 354: 2773-2782. 10.1056\/NEJMoa054209.","journal-title":"N Engl J Med"},{"key":"133_CR65","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.ijcard.2005.06.038","volume":"109","author":"TM Ng","year":"2006","unstructured":"Ng TM, Shurmur SW, Silver M, Nissen LR, O'Leary EL, Rigmaiden RS, Cieciorka M, Porter LL, Ineck BA, Kline ME, Puumala SE: Comparison of N-acetylcysteine and fenoldopam for preventing contrast-induced nephropathy (CAFCIN). Int J Cardiol. 2006, 109: 322-328. 10.1016\/j.ijcard.2005.06.038.","journal-title":"Int J Cardiol"},{"key":"133_CR66","doi-asserted-by":"publisher","first-page":"1863","DOI":"10.1093\/ndt\/gfl079","volume":"21","author":"E Macedo","year":"2006","unstructured":"Macedo E, Abdulkader R, Castro I, Sobrinho AC, Yu L, Vieira JM: Lack of protection of N-acetylcysteine (NAC) in acute renal failure related to elective aortic aneurysm repair-a randomized controlled trial. Nephrol Dial Transplant. 2006, 21: 1863-1869. 10.1093\/ndt\/gfl079.","journal-title":"Nephrol Dial Transplant"},{"key":"133_CR67","first-page":"559","volume":"64","author":"J Sochman","year":"2006","unstructured":"Sochman J, Krizova B: Prevention of contrast agent-induced renal impairment in patients with chronic renal insufficiency and heart disease by high-dose intravenous N-acetylcysteine: a pilot-ministudy. Kardiol Pol. 2006, 64: 559-564.","journal-title":"Kardiol Pol"},{"key":"133_CR68","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1016\/j.jvs.2004.09.026","volume":"40","author":"ST Rashid","year":"2004","unstructured":"Rashid ST, Salman M, Myint F, Baker DM, Agarwal S, Sweny P, Hamilton G: Prevention of contrast-induced nephropathy in vascular patients undergoing angiography: a randomized controlled trial of intravenous N-acetylcysteine. J Vasc Surg. 2004, 40: 1136-1141. 10.1016\/j.jvs.2004.09.026.","journal-title":"J Vasc Surg"},{"key":"133_CR69","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1148\/radiol.2393041456","volume":"239","author":"W Huber","year":"2006","unstructured":"Huber W, Eckel F, Hennig M, Rosenbrock H, Wacker A, Saur D, Sennefelder A, Hennico R, Schenk C, Meining A, et al: Prophylaxis of contrast material-induced nephropathy in patients in intensive care: acetylcysteine, theophylline, or both? A randomized study. Radiology. 2006, 239: 793-804. 10.1148\/radiol.2393041456.","journal-title":"Radiology"},{"key":"133_CR70","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1586\/14750708.3.6.773","volume":"3","author":"H Khalili","year":"2006","unstructured":"Khalili H, Dashti-Khaidaki S, Tabifar H, Ahmadinejad N, Ahmadi F: N-acetylcysteine in the prevention of contrast agent-induced nephrotoxicity in patients undergoing computed tomography studies. Therapy. 2006, 3: 773-777. 10.1586\/14750708.3.6.773.","journal-title":"Therapy"},{"key":"133_CR71","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/eurheartj\/ehi474","volume":"27","author":"EE Ozcan","year":"2006","unstructured":"Ozcan EE, Guneri S, Akdeniz B, Senaslan O, Aslan O, Badak O: Prospective randomized study of sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. Eur Heart J. 2006, 27: 83.","journal-title":"Eur Heart J"},{"key":"133_CR72","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/S0140-6736(03)14189-X","volume":"362","author":"R Birck","year":"2003","unstructured":"Birck R, Krzossok S, Markowetz F, Schnulle P, van der Woude FJ, Braun C: Acetylcysteine for prevention of contrast nephropathy: meta-analysis. Lancet. 2003, 362: 598-603. 10.1016\/S0140-6736(03)14189-X.","journal-title":"Lancet"},{"key":"133_CR73","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1016\/j.amjcard.2003.08.059","volume":"92","author":"DW Isenbarger","year":"2003","unstructured":"Isenbarger DW, Kent SM, O'Malley PG: Meta-analysis of randomized clinical trials on the usefulness of acetylcysteine for prevention of contrast nephropathy. Am J Cardiol. 2003, 92: 1454-1458. 10.1016\/j.amjcard.2003.08.059.","journal-title":"Am J Cardiol"},{"key":"133_CR74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1053\/j.ajkd.2003.09.009","volume":"43","author":"A Alonso","year":"2004","unstructured":"Alonso A, Lau J, Jaber BL, Weintraub A, Sarnak MJ: Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials. Am J Kidney Dis. 2004, 43: 1-9. 10.1053\/j.ajkd.2003.09.009.","journal-title":"Am J Kidney Dis"},{"key":"133_CR75","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1097\/01.ASN.0000116241.47678.49","volume":"15","author":"AV Kshirsagar","year":"2004","unstructured":"Kshirsagar AV, Poole C, Mottl A, Shoham D, Franceschini N, Tudor G, Agrawal M, Denu-Ciocca C, Magnus Ohman E, Finn WF: N-acetylcysteine for the prevention of radiocontrast induced nephropathy: a meta-analysis of prospective controlled trials. J Am Soc Nephrol. 2004, 15: 761-769. 10.1097\/01.ASN.0000116241.47678.49.","journal-title":"J Am Soc Nephrol"},{"key":"133_CR76","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1111\/j.1523-1755.2004.00516.x","volume":"65","author":"N Pannu","year":"2004","unstructured":"Pannu N, Manns B, Lee H, Tonelli M: Systematic review of the impact of N-acetylcysteine on contrast nephropathy. Kidney Int. 2004, 65: 1366-1374. 10.1111\/j.1523-1755.2004.00516.x.","journal-title":"Kidney Int"},{"key":"133_CR77","doi-asserted-by":"crossref","first-page":"77","DOI":"10.5414\/CNP62077","volume":"62","author":"V Guru","year":"2004","unstructured":"Guru V, Fremes SE: The role of N-acetylcysteine in preventing radiographic contrast-induced nephropathy. Clin Nephrol. 2004, 62: 77-83.","journal-title":"Clin Nephrol"},{"key":"133_CR78","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/1741-7015-2-38","volume":"2","author":"SM Bagshaw","year":"2004","unstructured":"Bagshaw SM, Ghali WA: Acetylcysteine for prevention of contrast-induced nephropathy after intravascular angiography: a systematic review and meta-analysis. BMC Med. 2004, 2: 38-10.1186\/1741-7015-2-38.","journal-title":"BMC Med"},{"key":"133_CR79","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1002\/clc.4960271106","volume":"27","author":"D Misra","year":"2004","unstructured":"Misra D, Leibowitz K, Gowda RM, Shapiro M, Khan IA: Role of N-acetylcysteine in prevention of contrast-induced nephropathy after cardiovascular procedures: a meta-analysis. Clin Cardiol. 2004, 27: 607-610. 10.1002\/clc.4960271106.","journal-title":"Clin Cardiol"},{"key":"133_CR80","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/j.amjmed.2004.06.046","volume":"117","author":"BK Nallamothu","year":"2004","unstructured":"Nallamothu BK, Shojania KG, Saint S, Hofer TP, Humes HD, Moscucci M, Bates ER: Is acetylcysteine effective in preventing contrast-related nephropathy? A meta-analysis. Am J Med. 2004, 117: 938-947. 10.1016\/j.amjmed.2004.06.046.","journal-title":"Am J Med"},{"key":"133_CR81","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1525-1497.2005.30323.x","volume":"20","author":"R Liu","year":"2005","unstructured":"Liu R, Nair D, Ix J, Moore DH, Bent S: N-acetylcysteine for the prevention of contrast-induced nephropathy. A systematic review and meta-analysis. J Gen Intern Med. 2005, 20: 193-200. 10.1111\/j.1525-1497.2005.30323.x.","journal-title":"J Gen Intern Med"},{"key":"133_CR82","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1002\/ccd.20342","volume":"64","author":"MH Duong","year":"2005","unstructured":"Duong MH, Mackenzie TA, Malenka DJ: N-acetylcysteine prophylaxis significantly reduces the risk of radiocontrast-induced nephropathy: comprehensive meta-analysis. Catheter Cardiovasc Interv. 2005, 64: 471-479. 10.1002\/ccd.20342.","journal-title":"Catheter Cardiovasc Interv"},{"key":"133_CR83","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.ahj.2005.01.055","volume":"151","author":"A Zagler","year":"2006","unstructured":"Zagler A, Azadpour M, Mercado C, Hennekens CH: N-acetylcysteine and contrast-induced nephropathy: a meta-analysis of 13 randomized trials. Am Heart J. 2006, 151: 140-145. 10.1016\/j.ahj.2005.01.055.","journal-title":"Am Heart J"},{"key":"133_CR84","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1136\/bmj.38693.516782.7C","volume":"332","author":"GG Biondi-Zoccai","year":"2006","unstructured":"Biondi-Zoccai GG, Lotrionte M, Abbate A, Testa L, Remigi E, Burzotta F, Valgimigli M, Romagnoli E, Crea F, Agostoni P: Compliance with QUOROM and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study. Br Med J. 2006, 332: 202-209. 10.1136\/bmj.38693.516782.7C.","journal-title":"Br Med J"},{"key":"133_CR85","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1001\/archinte.166.2.161","volume":"166","author":"SM Bagshaw","year":"2006","unstructured":"Bagshaw SM, McAlister FA, Manns BJ, Ghali WA: Acetylcysteine in the prevention of contrast-induced nephropathy: a case study of the pitfalls in the evolution of evidence. Arch Intern Med. 2006, 166: 161-166. 10.1001\/archinte.166.2.161.","journal-title":"Arch Intern Med"},{"key":"133_CR86","doi-asserted-by":"crossref","first-page":"224","DOI":"10.7326\/0003-4819-107-2-224","volume":"107","author":"KA L'Abb\u00e9","year":"1987","unstructured":"L'Abb\u00e9 KA, Detsky AS, O'Rourke K: Meta-analysis in clinical research. Ann Intern Med. 1987, 107: 224-233.","journal-title":"Ann Intern Med"},{"key":"133_CR87","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1198\/016214502760047131","volume":"97","author":"C Fraley","year":"2002","unstructured":"Fraley C, Raftery A: Model-based clustering, discriminant analysis, and density estimation. J Am Stat Assoc. 2002, 97: 611-631. 10.1198\/016214502760047131.","journal-title":"J Am Stat Assoc"},{"key":"133_CR88","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","volume":"17","author":"AR Jadad","year":"1996","unstructured":"Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ: Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials. 1996, 17: 1-12. 10.1016\/0197-2456(95)00134-4.","journal-title":"Control Clin Trials"},{"key":"133_CR89","doi-asserted-by":"publisher","first-page":"101","DOI":"10.2307\/3001666","volume":"10","author":"WG Cochran","year":"1954","unstructured":"Cochran WG: The combination of estimates from different experiments. Biometrics. 1954, 10: 101-129. 10.2307\/3001666.","journal-title":"Biometrics"},{"key":"133_CR90","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in meta-analyses. Br Med J. 2003, 327: 557-560. 10.1136\/bmj.327.7414.557.","journal-title":"Br Med J"},{"key":"133_CR91","doi-asserted-by":"publisher","first-page":"3251","DOI":"10.1002\/1097-0258(20001215)19:23<3251::AID-SIM625>3.0.CO;2-2","volume":"19","author":"SJ Sharp","year":"2000","unstructured":"Sharp SJ, Thompson SG: Analysing the relationship between treatment effect and underlying risk in meta-analysis: comparison and development of approaches. Stat Med. 2000, 19: 3251-3274. 10.1002\/1097-0258(20001215)19:23<3251::AID-SIM625>3.0.CO;2-2.","journal-title":"Stat Med"},{"key":"133_CR92","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1164\/rccm.200204-302OC","volume":"166","author":"PQ Eichacker","year":"2002","unstructured":"Eichacker PQ, Parent C, Kalil A, Esposito C, Cui X, Banks SM, Gerstenberger EP, Fitz Y, Danner RL, Natanson C: Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis. Am J Respir Crit Care Med. 2002, 166: 1197-1205. 10.1164\/rccm.200204-302OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"133_CR93","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1001\/jama.275.19.1489","volume":"275","author":"EM Levy","year":"1996","unstructured":"Levy EM, Viscoli CM, Horwitz RI: The effect of acute renal failure on mortality. A cohort analysis. JAMA. 1996, 275: 1489-1494. 10.1001\/jama.275.19.1489.","journal-title":"JAMA"},{"key":"133_CR94","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/S0002-9343(97)00150-2","volume":"103","author":"PA McCullough","year":"1997","unstructured":"McCullough PA, Wolyn R, Rocher LL, Levin RN, O'Neill WW: Acute renal failure after coronary intervention: incidence, risk factors, and relationship to mortality. Am J Med. 1997, 103: 368-375. 10.1016\/S0002-9343(97)00150-2.","journal-title":"Am J Med"},{"key":"133_CR95","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.1001\/jama.295.23.2765","volume":"295","author":"N Pannu","year":"2006","unstructured":"Pannu N, Wiebe N, Tonelli M: Prophylaxis strategies for contrast-induced nephropathy. JAMA. 2006, 295: 2765-2779. 10.1001\/jama.295.23.2765.","journal-title":"JAMA"},{"key":"133_CR96","first-page":"1393","volume":"44","author":"R Mehran","year":"2004","unstructured":"Mehran R, Aymong ED, Nikolsky E, Lasic Z, Iakovou I, Fahy M, Mintz GS, Lansky AJ, Moses JW, Stone GW, et al: A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention. J Am Coll Cardiol. 2004, 44: 1393-1399.","journal-title":"J Am Coll Cardiol"},{"key":"133_CR97","first-page":"1","volume":"61","author":"R Miller","year":"1974","unstructured":"Miller R: The jackknife \u2013 a review. Biometrika. 1974, 61: 1-15.","journal-title":"Biometrika"},{"key":"133_CR98","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1214\/aoms\/1177729747","volume":"21","author":"WJ Dixon","year":"1950","unstructured":"Dixon WJ: Analysis of extreme values. Ann Math Stat. 1950, 21: 488-506.","journal-title":"Ann Math Stat"},{"key":"133_CR99","doi-asserted-by":"crossref","first-page":"859","DOI":"10.2214\/ajr.136.5.859","volume":"136","author":"RL Eisenberg","year":"1981","unstructured":"Eisenberg RL, Bank WO, Hedgock MW: Renal failure after major angiography can be avoided with hydration. AJR Am J Roentgenol. 1981, 136: 859-861.","journal-title":"AJR Am J Roentgenol"},{"key":"133_CR100","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1001\/archinte.162.3.329","volume":"162","author":"C Mueller","year":"2002","unstructured":"Mueller C, Buerkle G, Buettner HJ, Petersen J, Perruchoud AP, Eriksson U, Marsch S, Roskamm H: Prevention of contrast media-associated nephropathy: randomized comparison of 2 hydration regimens in 1620 patients undergoing coronary angioplasty. Arch Intern Med. 2002, 162: 329-336. 10.1001\/archinte.162.3.329.","journal-title":"Arch Intern Med"},{"key":"133_CR101","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1097\/01.ASN.0000107562.68920.92","volume":"15","author":"S Fishbane","year":"2004","unstructured":"Fishbane S, Durham JH, Marzo K, Rudnick M: N-acetylcysteine in the prevention of radiocontrast-induced nephropathy. J Am Soc Nephrol. 2004, 15: 251-260. 10.1097\/01.ASN.0000107562.68920.92.","journal-title":"J Am Soc Nephrol"},{"key":"133_CR102","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.1001\/jama.291.19.2328","volume":"291","author":"GJ Merten","year":"2004","unstructured":"Merten GJ, Burgess WP, Gray LV, Holleman JH, Roush TS, Kowalchuk GJ, Bersin RM, Van Moore A, Simonton CA, Rittase RA, et al: Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial. JAMA. 2004, 291: 2328-2334. 10.1001\/jama.291.19.2328.","journal-title":"JAMA"},{"key":"133_CR103","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000079804","volume":"27","author":"U Hoffmann","year":"2004","unstructured":"Hoffmann U, Banas B, Fischereder M, Kramer BK: N-acetylcysteine in the prevention of radiocontrast-induced nephropathy: clinical trials and end points. Kidney Blood Press Res. 2004, 27: 161-166. 10.1159\/000079804.","journal-title":"Kidney Blood Press Res"},{"key":"133_CR104","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1080\/08860220600580407","volume":"28","author":"O Toprak","year":"2006","unstructured":"Toprak O: Interactions between serum creatinine, volume status, N-acetylcysteine, and contrast-induced nephropathy. Ren Fail. 2006, 28: 265-266. 10.1080\/08860220600580407.","journal-title":"Ren Fail"},{"key":"133_CR105","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1148\/radiol.2402051532","volume":"240","author":"M Brautigam","year":"2006","unstructured":"Brautigam M, Persson PB: Do iodinated contrast media interfere with renal tubular creatinine secretion?. Radiology. 2006, 240: 615-10.1148\/radiol.2402051532.","journal-title":"Radiology"},{"key":"133_CR106","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1097\/01.ASN.0000106780.14856.55","volume":"15","author":"U Hoffmann","year":"2004","unstructured":"Hoffmann U, Fischereder M, Kr\u00fcger B, Drobnik W, Kr\u00e4mer BK: The value of N-acetylcysteine in the prevention of radiocontrast agent-induced nephropathy seems questionable. J Am Soc Nephrol. 2004, 15: 407-410. 10.1097\/01.ASN.0000106780.14856.55.","journal-title":"J Am Soc Nephrol"},{"key":"133_CR107","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1016\/S0026-0495(03)00193-8","volume":"52","author":"C Perlemoine","year":"2003","unstructured":"Perlemoine C, Beauvieux MC, Rigalleau V, Baillet L, Barthes N, Derache P, Gin H: Interest of cystatin C in screening diabetic patients for early impairment of renal function. Metabolism. 2003, 52: 1258-1264. 10.1016\/S0026-0495(03)00193-8.","journal-title":"Metabolism"},{"key":"133_CR108","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1093\/clinchem\/48.5.699","volume":"48","author":"OF Laterza","year":"2002","unstructured":"Laterza OF, Price CP, Scott MG: Cystatin C: an improved estimator of glomerular filtration rate?. Clin Chem. 2002, 48: 699-707.","journal-title":"Clin Chem"},{"key":"133_CR109","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1001\/jama.294.3.342","volume":"294","author":"KE Burns","year":"2005","unstructured":"Burns KE, Chu MW, Novick RJ, Fox SA, Gallo K, Martin CM, Stitt LW, Heidenheim AP, Myers ML, Moist L: Perioperative N-acetylcysteine to prevent renal dysfunction in high-risk patients undergoing CABG surgery: a randomized controlled trial. JAMA. 2005, 294: 342-350. 10.1001\/jama.294.3.342.","journal-title":"JAMA"},{"key":"133_CR110","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1213\/01.ANE.0000219590.79796.66","volume":"102","author":"MS Hynninen","year":"2006","unstructured":"Hynninen MS, Niemi TT, Poyhia R, Raininko EI, Salmenpera MT, Lepantalo MJ, Railo MJ, Tallgren MK: N-acetylcysteine for the prevention of kidney injury in abdominal aortic surgery: a randomized, double-blind, placebo-controlled trial. Anesth Analg. 2006, 102: 1638-1645. 10.1213\/01.ANE.0000219590.79796.66.","journal-title":"Anesth Analg"}],"container-title":["BMC Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1741-7015-5-32.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1741-7015-5-32\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1741-7015-5-32.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T10:06:53Z","timestamp":1737540413000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmedicine.biomedcentral.com\/articles\/10.1186\/1741-7015-5-32"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,14]]},"references-count":110,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["133"],"URL":"https:\/\/doi.org\/10.1186\/1741-7015-5-32","relation":{},"ISSN":["1741-7015"],"issn-type":[{"value":"1741-7015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,14]]},"article-number":"32"}}