{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:59:27Z","timestamp":1790355567595,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Retrovirology"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Retroviruses have been linked to a variety of diseases such as neoplastic and immunodeficiency disorders and neurologic and respiratory diseases. Recently, a novel infectious human retrovirus, the xenotropic murine leukemia virus-related virus (XMRV), has been identified in cohorts of patients with either a familial type of prostate cancer or chronic fatigue syndrome. The apparent unrelatedness of these diseases raised the question of the potential involvement of XMRV in other diseases.<\/jats:p><jats:p>Here, we investigated the presence of XMRV in a selection of pediatric idiopathic infectious diseases with symptoms that are suggestive of a retroviral infection, as well as in children with respiratory diseases and in adult patients with spondyloarthritis (SpA). Using a XMRV<jats:italic>env<\/jats:italic>-nested PCR, we screened 72 DNA samples obtained from 62 children hospitalized in the Montpellier university hospital (France) for hematological, neurological or inflammatory pathologies, 80 DNA samples from nasopharyngeal aspirates from children with respiratory diseases and 19 DNA samples from SpA. None of the samples tested was positive for XMRV or MLV-like<jats:italic>env<\/jats:italic>sequences, indicating that XMRV is not involved in these pathologies.<\/jats:p>","DOI":"10.1186\/1742-4690-7-63","type":"journal-article","created":{"date-parts":[[2010,8,11]],"date-time":"2010-08-11T20:42:28Z","timestamp":1281559348000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["No evidence for XMRV association in pediatric idiopathic diseases in France"],"prefix":"10.1186","volume":"7","author":[{"given":"Eric","family":"Jeziorski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Foulongne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Ludwig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamel","family":"Louhaem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Chiocchia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Segondy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Rodi\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Sitbon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Courgnaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,8,2]]},"reference":[{"key":"1866_CR1","volume-title":"Retroviruses Cold Spring Harbor Laboratory Press","author":"J Coffin","year":"1997","unstructured":"Coffin J, Hughes SH, Varmus HE: Retroviruses Cold Spring Harbor Laboratory Press. 1997, Cold Spring Harbor, NY"},{"key":"1866_CR2","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1128\/MMBR.00033-07","volume":"72","author":"C Voisset","year":"2008","unstructured":"Voisset C, Weiss RA, Griffiths DJ: Human RNA \"rumor\" viruses: the search for novel human retroviruses in chronic disease. 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