{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T04:40:49Z","timestamp":1772858449125,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Trials"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/1745-6215-15-166","type":"journal-article","created":{"date-parts":[[2014,5,10]],"date-time":"2014-05-10T17:02:05Z","timestamp":1399741325000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Effectiveness of the Chest Pain Choice decision aid in emergency department patients with low-risk chest pain: study protocol for a multicenter randomized trial"],"prefix":"10.1186","volume":"15","author":[{"given":"Ryan T","family":"Anderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor M","family":"Montori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilay D","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry H","family":"Ting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurie J","family":"Pencille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Demers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A","family":"Kline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah B","family":"Diercks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judd E","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A","family":"Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason T","family":"Schaffer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeph","family":"Herrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Branda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Leblanc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik P","family":"Hess","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,5,10]]},"reference":[{"issue":"26","key":"2053_CR1","first-page":"1","volume":"2010","author":"R Niska","year":"2007","unstructured":"Niska R, Bhuiya F, Xu J: National hospital ambulatory medical care survey, emergency department summary. Natl Health Stat Rep. 2007, 2010 (26): 1-31.","journal-title":"Natl Health Stat Rep"},{"issue":"2","key":"2053_CR2","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1136\/hrt.2003.027599","volume":"91","author":"S Goodacre","year":"2005","unstructured":"Goodacre S, Cross E, Arnold J, Angelini K, Capewell S, Nicholl J: The health care burden of acute chest pain. Heart. 2005, 91 (2): 229-230. 10.1136\/hrt.2003.027599.","journal-title":"Heart"},{"key":"2053_CR3","volume-title":"Hospital stays for circulatory diseases","author":"Healthcare utilization project statistical brief #26","year":"2004","unstructured":"Healthcare utilization project statistical brief #26: Hospital stays for circulatory diseases. 2004, Rockville, Maryland, USA: Agency for healthcare research and quality,http:\/\/www.hcup-us.ahrq.gov\/reports\/statbriefs\/sb26.pdf,"},{"issue":"4","key":"2053_CR4","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1067\/mem.2001.118010","volume":"38","author":"S Goodacre","year":"2001","unstructured":"Goodacre S, Mason S, Arnold J, Angelini K: Psychologic morbidity and health-related quality of life of patients assessed in a chest pain observation unit. Ann Emerg Med. 2001, 38 (4): 369-376. 10.1067\/mem.2001.118010.","journal-title":"Ann Emerg Med"},{"issue":"5","key":"2053_CR5","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.annemergmed.2005.10.013","volume":"47","author":"AM Mitchell","year":"2006","unstructured":"Mitchell AM, Garvey JL, Chandra A, Diercks D, Pollack CV, Kline JA: Prospective multicenter study of quantitative pretest probability assessment to exclude acute coronary syndrome for patients evaluated in emergency department chest pain units. Ann Emerg Med. 2006, 47 (5): 447-","journal-title":"Ann Emerg Med"},{"issue":"3","key":"2053_CR6","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1097\/HPC.0b013e3182315a85","volume":"10","author":"SA Mahler","year":"2011","unstructured":"Mahler SA, Hiestand BC, Goff DC, Hoekstra JW, Miller CD: Can the heart score safely reduce stress testing and cardiac imaging in patients at low risk for major adverse cardiac events?. Crit Pathw Cardiol. 2011, 10 (3): 128-133. 10.1097\/HPC.0b013e3182315a85.","journal-title":"Crit Pathw Cardiol"},{"issue":"2","key":"2053_CR7","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.annemergmed.2011.07.026","volume":"59","author":"EP Hess","year":"2012","unstructured":"Hess EP, Brison RJ, Perry JJ, Calder LA, Thiruganasambandamoorthy V, Agarwal D, Sadosty AT, Silvilotti ML, Jaffe AS, Montori VM, Wells GA, Stiell IG: Development of a clinical prediction rule for 30-day cardiac events in emergency department patients with chest pain and possible acute coronary syndrome. Ann Emerg Med. 2012, 59 (2): 115-125. 10.1016\/j.annemergmed.2011.07.026. e1","journal-title":"Ann Emerg Med"},{"issue":"10","key":"2053_CR8","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1503\/cmaj.092119","volume":"182","author":"EP Hess","year":"2010","unstructured":"Hess EP, Agarwal D, Chandra S, Murad MH, Erwin PJ, Hollander JE, Montori VM, Stiell IG: Diagnostic accuracy of the TIMI risk score in patients with chest pain in the emergency department: a meta-analysis. CMAJ. 2010, 182 (10): 1039-1044. 10.1503\/cmaj.092119.","journal-title":"CMAJ"},{"issue":"4","key":"2053_CR9","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/j.ahj.2012.06.025","volume":"164","author":"SJ Aldous","year":"2012","unstructured":"Aldous SJ, Richards M, Cullen L, Troughton R, Than M: A 2-hour thrombolysis in myocardial infarction score outperforms other risk stratification tools in patients presenting with possible acute coronary syndromes: comparison of chest pain risk stratification tools. Am Heart J. 2012, 164 (4): 516-523. 10.1016\/j.ahj.2012.06.025.","journal-title":"Am Heart J"},{"issue":"1","key":"2053_CR10","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1001\/jamainternmed.2013.11362","volume":"174","author":"M Than","year":"2014","unstructured":"Than M, Aldous S, Lord SJ, Goodacre S, Frampton CM, Troughton R, George P, Florkowski CM, Ardagh M, Smyth D, Jardine DL, Peacock WF, Young J, Hamilton G, Deely JM, Cullen L, Richards AM: A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial. JAMA Intern Med. 2014, 174 (1): 51-58. 10.1001\/jamainternmed.2013.11362.","journal-title":"JAMA Intern Med"},{"issue":"3","key":"2053_CR11","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1161\/CIRCOUTCOMES.111.964791","volume":"5","author":"EP Hess","year":"2012","unstructured":"Hess EP, Knoedler MA, Shah ND, Kline JA, Breslin M, Branda ME, Pencille LJ, Asplin BR, Nestler DM, Sadosty AT, Stiell IG, Ting HH, Montori VM: The chest pain choice decision aid: a randomized trial. Circ Cardiovasc Qual Outcomes. 2012, 5 (3): 251-259. 10.1161\/CIRCOUTCOMES.111.964791.","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"1","key":"2053_CR12","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1161\/CIRCIMAGING.113.001080","volume":"7","author":"JA Kline","year":"2014","unstructured":"Kline JA, Jones AE, Shapiro NI, Hernandez J, Hogg MM, Troyer J, Nelson RD: Multicenter randomized trial of quantitative pretest probability to reduce unnecessary medical radiation exposure in emergency department patients with chest pain and dyspnea. Circ Cardiovasc Imaging. 2014, 7 (1): 66-73. 10.1161\/CIRCIMAGING.113.001080.","journal-title":"Circ Cardiovasc Imaging"},{"issue":"5","key":"2053_CR13","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/S0277-9536(99)00145-8","volume":"49","author":"C Charles","year":"1999","unstructured":"Charles C, Gafni A, Whelan T: Decision-making in the physician-patient encounter: revisiting the shared treatment decision-making model. Soc Sci Med. 1999, 49 (5): 651-661. 10.1016\/S0277-9536(99)00145-8.","journal-title":"Soc Sci Med"},{"key":"2053_CR14","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/1745-6215-11-57","volume":"11","author":"MA Pierce","year":"2010","unstructured":"Pierce MA, Hess EP, Kline JA, Shah ND, Breslin M, Branda ME, Pencille LJ, Asplin BR, Nestler DM, Sadosty AT, Stiell IG, Ting HH, Montori VM: The Chest Pain Choice trial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency department. Trials. 2010, 11: 57-10.1186\/1745-6215-11-57.","journal-title":"Trials"},{"key":"2053_CR15","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1472-6947-5-26","volume":"5","author":"JA Kline","year":"2005","unstructured":"Kline JA, Johnson CL, Pollack CV, Diercks DB, Hollander JE, Newgard CD, Garvey JL: Pretest probability assessment derived from attribute matching. BMC Med Inform Decis Mak. 2005, 5: 26-10.1186\/1472-6947-5-26.","journal-title":"BMC Med Inform Decis Mak"},{"issue":"6","key":"2053_CR16","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.annemergmed.2008.09.034","volume":"53","author":"JA Kline","year":"2009","unstructured":"Kline JA, Zeitouni RA, Hernandez-Nino J, Jones AE: Randomized trial of computerized quantitative pretest probability in low-risk chest pain patients: effect on safety and resource use. Ann Emerg Med. 2009, 53 (6): 727-735. 10.1016\/j.annemergmed.2008.09.034. e721","journal-title":"Ann Emerg Med"},{"issue":"5","key":"2053_CR17","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.jclinepi.2008.02.009","volume":"62","author":"PJ Karanicolas","year":"2009","unstructured":"Karanicolas PJ, Montori VM, Devereaux PJ, Schunemann H, Guyatt GH: A new \u2018mechanistic-practical\u2019 framework for designing and interpreting randomized trials. J Clin Epidemiol. 2009, 62 (5): 479-484. 10.1016\/j.jclinepi.2008.02.009.","journal-title":"J Clin Epidemiol"},{"key":"2053_CR18","doi-asserted-by":"publisher","first-page":"c332","DOI":"10.1136\/bmj.c332","volume":"340","author":"KF Schulz","year":"2010","unstructured":"Schulz KF, Altman DG, Moher D: Consort statement: updated guidelines for reporting parallel group randomised trials. BMJ. 2010, 340: c332-10.1136\/bmj.c332.","journal-title":"BMJ"},{"issue":"1","key":"2053_CR19","doi-asserted-by":"publisher","first-page":"103","DOI":"10.2307\/2529712","volume":"31","author":"SJ Pocock","year":"1975","unstructured":"Pocock SJ, Simon R: Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics. 1975, 31 (1): 103-115. 10.2307\/2529712.","journal-title":"Biometrics"},{"issue":"7565","key":"2053_CR20","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1136\/bmj.38926.629329.AE","volume":"333","author":"G Elwyn","year":"2006","unstructured":"Elwyn G, O'Connor A, Stacey D, Volk R, Edwards A, Coulter A, Thomson R, Barratt A, Barry M, Bernstein S, Butow P, Clarke A, Entwistle V, Feldman-Stewart D, Holmes-Rovner M, Llewellyn-Thomas H, Moumjid N, Mulley A, Ruland C, Sepucha K, Sykes A, Whelan T, International Patient Decision Aids Standards (IPDAS) Collaboration: Developing a quality criteria framework for patient decision aids: online international Delphi consensus process. BMJ. 2006, 333 (7565): 417-10.1136\/bmj.38926.629329.AE.","journal-title":"BMJ"},{"issue":"1","key":"2053_CR21","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/j.1369-7625.2004.00311.x","volume":"8","author":"G Elwyn","year":"2005","unstructured":"Elwyn G, Hutchings H, Edwards A, Rapport F, Wensing M, Cheung WY, Grol R: The OPTION scale: measuring the extent that clinicians involve patients in decision-making tasks. Health Expect. 2005, 8 (1): 34-42. 10.1111\/j.1369-7625.2004.00311.x.","journal-title":"Health Expect"},{"issue":"1","key":"2053_CR22","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1177\/0272989X9501500105","volume":"15","author":"AM O'Connor","year":"1995","unstructured":"O'Connor AM: Validation of a decisional conflict scale. Med Decis Making. 1995, 15 (1): 25-30. 10.1177\/0272989X9501500105.","journal-title":"Med Decis Making"},{"issue":"5","key":"2053_CR23","first-page":"510","volume":"37","author":"DH Thom","year":"1999","unstructured":"Thom DH, Ribisl KM, Stewart AL, Luke DA: Further validation and reliability testing of the trust in physician scale. Stanford Trust Stud Phys Med Care. 1999, 37 (5): 510-517.","journal-title":"Stanford Trust Stud Phys Med Care"},{"issue":"1","key":"2053_CR24","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1111\/j.1742-6723.2010.01256.x","volume":"22","author":"L Cullen","year":"2010","unstructured":"Cullen L, Than M, Brown AF, Richards M, Parsonage W, Flaws D, Hollander JE, Christenson RH, Kline JA, Goodacre S, Jaffe AS: Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia. Emerg Med Australas. 2010, 22 (1): 35-55. 10.1111\/j.1742-6723.2010.01256.x.","journal-title":"Emerg Med Australas"},{"issue":"16","key":"2053_CR25","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1161\/CIR.0b013e31826e1058","volume":"126","author":"K Thygesen","year":"2012","unstructured":"Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, Katus HA, Lindahl B, Morrow DA, Clemmensen PM, Johanson P, Hod H, Underwood R, Bax JJ, Bonow RO, Pinto F, Gibbons RJ, Fox KA, Atar D, Newby LK, Galvani M, Hamm CW, Uretsky BF, Steg PG, Wijns W, Bassand JP, Menasch\u00e9 P, Ravkilde J, Ohman EM, Joint ESC\/ACCF\/AHA\/WHF Task Force for the Universal Definition of Myocardial Infarction: Third universal definition of myocardial infarction. Circulation. 2012, 126 (16): 2020-2035. 10.1161\/CIR.0b013e31826e1058.","journal-title":"Circulation"},{"issue":"6","key":"2053_CR26","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.annemergmed.2004.08.009","volume":"44","author":"JE Hollander","year":"2004","unstructured":"Hollander JE, Blomkalns AL, Brogan GX, Diercks DB, Field JM, Garvey JL, Gibler WB, Henry TD, Hoekstra JW, Holroyd BR, Hong Y, Kirk JD, O'Neil BJ, Jackson RE, Multidisciplinary Standardized Reporting Criteria Task Force: Standardized reporting guidelines for studies evaluating risk stratification of emergency department patients with potential acute coronary syndromes. Ann Emerg Med. 2004, 44 (6): 589-598. 10.1016\/j.annemergmed.2004.08.009.","journal-title":"Ann Emerg Med"},{"issue":"2","key":"2053_CR27","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","volume":"42","author":"PA Harris","year":"2009","unstructured":"Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG: Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009, 42 (2): 377-381. 10.1016\/j.jbi.2008.08.010.","journal-title":"J Biomed Inform"},{"issue":"7365","key":"2053_CR28","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1136\/bmj.325.7365.652","volume":"325","author":"D Fergusson","year":"2002","unstructured":"Fergusson D, Aaron SD, Guyatt G, Hebert P: Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis. BMJ. 2002, 325 (7365): 652-654. 10.1136\/bmj.325.7365.652.","journal-title":"BMJ"},{"issue":"1","key":"2053_CR29","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","volume":"36","author":"A Elixhauser","year":"1998","unstructured":"Elixhauser A, Steiner C, Harris DR, Coffey RM: Comorbidity measures for use with administrative data. Med Care. 1998, 36 (1): 8-27. 10.1097\/00005650-199801000-00004.","journal-title":"Med Care"},{"issue":"2","key":"2053_CR30","doi-asserted-by":"publisher","first-page":"E78","DOI":"10.1503\/cmaj.081232","volume":"182","author":"MB Harrison","year":"2010","unstructured":"Harrison MB, Legare F, Graham ID, Fervers B: Adapting clinical practice guidelines to local context and assessing barriers to their use. CMAJ. 2010, 182 (2): E78-E84. 10.1503\/cmaj.081232.","journal-title":"CMAJ"},{"issue":"21","key":"2053_CR31","doi-asserted-by":"publisher","first-page":"2483","DOI":"10.1001\/jama.2008.730","volume":"300","author":"MH Murad","year":"2008","unstructured":"Murad MH, Montori VM, Guyatt GH: Incorporating patient preferences in evidence-based medicine. JAMA. 2008, 300 (21): 2483-2484. 2483; author reply","journal-title":"JAMA"}],"container-title":["Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1745-6215-15-166.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T03:50:33Z","timestamp":1630554633000},"score":1,"resource":{"primary":{"URL":"https:\/\/trialsjournal.biomedcentral.com\/articles\/10.1186\/1745-6215-15-166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,10]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["2053"],"URL":"https:\/\/doi.org\/10.1186\/1745-6215-15-166","relation":{},"ISSN":["1745-6215"],"issn-type":[{"value":"1745-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,10]]},"assertion":[{"value":"1 January 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"166"}}