{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:16:05Z","timestamp":1788520565982,"version":"build-2803163510"},"reference-count":86,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cough"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cough is one of the most common complaints for which patients seek medical attention. Misdiagnosis and mistreatment of cough exist commonly in China. The prevalence of acute cough caused by upper airway infection fluctuates between 9% and 64% in the community, for chronic cough, the prevalence &gt;10% in most surveys, ranging from 7.2%-33%. The common causes of chronic cough are upper airway cough syndrome (previously called as post nasal drip syndrome [PNDS]), cough variant asthma (CVA), gastroesophageal reflux related cough (GERD) and eosinophilic bronchitis (EB). There is a regional discrepancy regarding the prevalence of common causes of cough and distribution of gender among China, UK, USA, the most common cause of chronic cough in China are CVA, followed by UACS, EB and atopic cough (AC), the male is almost equal to female in numbers in China. The risk factors for cough includes cold air, smoking, environmental pollutants, noxious substances and allergens, and unreasonable diet habits.<\/jats:p>","DOI":"10.1186\/1745-9974-9-18","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T12:14:37Z","timestamp":1373285677000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Epidemiology of cough in relation to China"],"prefix":"10.1186","volume":"9","author":[{"given":"Kefang","family":"Lai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayu","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baojuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanshan","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,8]]},"reference":[{"key":"105_CR1","volume-title":"National ambulatory medical care survey: 1998 summary","author":"DA Woodwell","year":"2000","unstructured":"Woodwell DA: National ambulatory medical care survey: 1998 summary. 2000, Hyattsville, MD: National Center for Health Statistics"},{"key":"105_CR2","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1177\/1479972307084252","volume":"5","author":"AH Moriee","year":"2008","unstructured":"Moriee AH: Chronic cough: Epidemiology. Chron Respir Dis. 2008, 5: 43-47. 10.1177\/1479972307084252.","journal-title":"Chron Respir Dis"},{"issue":"1","key":"105_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1745-9974-3-5","volume":"3","author":"CF Everett","year":"2007","unstructured":"Everett CF, Kastelik JA, Thompson RH, Morice AH: Chronic persistent cough in the community: A questionnaire survey. Cough. 2007, 3 (1): 5-10.1186\/1745-9974-3-5.","journal-title":"Cough"},{"key":"105_CR4","first-page":"645","volume":"31","author":"KF Lai","year":"2011","unstructured":"Lai KF, Li BK, Wang FX, Chen RC, Liu XY, Zhong NS: Survey on the diagnosis and management of the patients with chronic cough. Int J Respir. 2011, 31: 645-647.","journal-title":"Int J Respir"},{"key":"105_CR5","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1017\/S0950268800056764","volume":"111","author":"DA Tyrrell","year":"1993","unstructured":"Tyrrell DA, Cohen S, Schlarb JE: Signs and symptoms in common cold. Epidemiol Infect. 1993, 111: 143-156. 10.1017\/S0950268800056764.","journal-title":"Epidemiol Infect"},{"key":"105_CR6","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1046\/j.1526-4637.2003.03019.x","volume":"4","author":"R Eccles","year":"2003","unstructured":"Eccles R, Loose I, Jawad M, Nyman L: Effects of acetylsalicylic acid on sore throat pain and other pain symptoms associated with acute upper respiratory tract infection. Pain Med. 2003, 4: 118-124. 10.1046\/j.1526-4637.2003.03019.x.","journal-title":"Pain Med"},{"key":"105_CR7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1378\/chest.99.1.20","volume":"99","author":"RA Barbee","year":"1991","unstructured":"Barbee RA, Halonen M, Kaltenborn WT, Burrows B: A longitudinal study of respiratory symptoms in a community population sample. Correlations with smoking, allergen skin-test reactivity, and serum IgE. Chest. 1991, 99: 20-26. 10.1378\/chest.99.1.20.","journal-title":"Chest"},{"key":"105_CR8","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1183\/09031936.03.00121103","volume":"22","author":"I Cerveri","year":"2003","unstructured":"Cerveri I, Accordini S, Corsico A, et al: Chronic cough and phlegm in young adults. Eur Respir J. 2003, 22: 413-417. 10.1183\/09031936.03.00121103.","journal-title":"Eur Respir J"},{"key":"105_CR9","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1164\/ajrccm.159.4.9807052","volume":"159","author":"E Zemp","year":"1999","unstructured":"Zemp E, Elsasser S, Schindler C, K\u00fcnzli N, Perruchoud AP, Domenighetti G, Medici T, Ackermann-Liebrich U, Leuenberger P, Monn C, Bolognini G, Bongard JP, Br\u00e4ndli O, Karrer W, Keller R, Sch\u00f6ni MH, Tschopp JM, Villiger B, Zellweger JP: Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study). Am J Respir Crit Care Med. 1999, 159: 1257-1266. 10.1164\/ajrccm.159.4.9807052.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR10","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1136\/jech.47.1.27","volume":"47","author":"P Cullinan","year":"1993","unstructured":"Cullinan P: Aetiological factors in persistent sputum production: a case\u2013control study. J Epidemiol Community Health. 1993, 47: 27-31. 10.1136\/jech.47.1.27.","journal-title":"J Epidemiol Community Health"},{"key":"105_CR11","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1183\/09031936.01.00098701","volume":"18","author":"C Janson","year":"2001","unstructured":"Janson C, Chinn S, Jarvis D, Burney P: Determinants of cough in young adults participating in the European Community Respiratory Health Survey. Eur Respir J. 2001, 18: 647-654. 10.1183\/09031936.01.00098701.","journal-title":"Eur Respir J"},{"key":"105_CR12","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1136\/thx.2006.060087","volume":"61","author":"AC Ford","year":"2006","unstructured":"Ford AC, Forman D, Moayyedi P, Morice AH: Cough in the community: a cross sectional survey and the relationship to gastroin-testinal symptoms. Thorax. 2006, 61: 975-979. 10.1136\/thx.2006.060087.","journal-title":"Thorax"},{"key":"105_CR13","first-page":"123","volume":"27","author":"RC Chen","year":"2006","unstructured":"Chen RC, Lai KF, Liu CL, Luo W, Zhong NS: An epidemiologic study of cough in young college students in Guangzhou. Chin J Epidemiol. 2006, 27: 123-126.","journal-title":"Chin J Epidemiol"},{"key":"105_CR14","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1183\/09031936.93.04030257","volume":"4","author":"B Lundback","year":"1991","unstructured":"Lundback B, Nystrom L, Rosenhall L, Stjernberg N: Obstructive lung disease in northern Sweden: respiratory symptoms assessed in a postal survey. Eur Respir J. 1991, 4: 257-266.","journal-title":"Eur Respir J"},{"key":"105_CR15","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1378\/chest.109.5.1262","volume":"109","author":"D Ludviksdottir","year":"1996","unstructured":"Ludviksdottir D, Bjornsson E, Janson C, Boman G: Habitual coughing and its associations with asthma, anxiety, and gastroesophageal reflux. Chest. 1996, 109: 1262-1268. 10.1378\/chest.109.5.1262.","journal-title":"Chest"},{"key":"105_CR16","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1164\/ajrccm.164.3.2004029","volume":"164","author":"DB Coultas","year":"2001","unstructured":"Coultas DB, Mapel D, Gagnon R, Lydick E: The health impact of undiagnosed airfl ow obstruction in a national sample of United States adults. Am J Respir Crit Care Med. 2001, 164: 372-377. 10.1164\/ajrccm.164.3.2004029.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR17","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/1745-9974-2-11","volume":"2","author":"ER Carter","year":"2006","unstructured":"Carter ER, Debley JS, Redding GR: Chronic productive cough in school children: prevalence and associations with asthma and environmental tobacco smoke exposure. Cough. 2006, 2: 11-10.1186\/1745-9974-2-11.","journal-title":"Cough"},{"key":"105_CR18","first-page":"645","volume":"31","author":"KF Lai","year":"2011","unstructured":"Lai KF, Li BK, Wang FX, Chen RC, Liu XY, Zhong NS: Survey on the diagnosis and management of the patients with chronic cough. Int J Respir. 2011, 31: 645-647.","journal-title":"Int J Respir"},{"issue":"3","key":"105_CR19","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1378\/chest.12-0441","volume":"143","author":"KF Lai","year":"2013","unstructured":"Lai KF, Chen RC, Lin JT, Huang KW, Shen HH, Kong LF, Zhou X, Luo ZY, Yang L, Wen FQ, Zhong NS: A prospective, multicenter survey on causes of chronic cough in china. Chest. 2013, 143 (3): 613-620. 10.1378\/chest.12-0441.","journal-title":"Chest"},{"key":"105_CR20","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1136\/adc.74.6.531","volume":"74","author":"P Munyard","year":"1996","unstructured":"Munyard P, Bush A: How much coughing is normal?. Arch Dis Child. 1996, 74: 531-534. 10.1136\/adc.74.6.531.","journal-title":"Arch Dis Child"},{"key":"105_CR21","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1378\/chest.115.2.434","volume":"115","author":"AO Faniran","year":"1999","unstructured":"Faniran AO, Peat JK, Woolcock AJ: Measuring persistent cough in children in epidemiological studies: development of a questionnaire and assessment of prevalence in two countries. Chest. 1999, 115: 434-439. 10.1378\/chest.115.2.434.","journal-title":"Chest"},{"key":"105_CR22","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1136\/bmj.306.6889.1386","volume":"306","author":"DK Luyt","year":"1993","unstructured":"Luyt DK, Burton PR, Simpson H: Epidemiological study of wheeze, doctor diagnosed asthma, and cough in preschool children in Leicestershire. Br Med J. 1993, 306: 1386-1390. 10.1136\/bmj.306.6889.1386.","journal-title":"Br Med J"},{"key":"105_CR23","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1136\/adc.79.5.411","volume":"79","author":"AO Faniran","year":"1998","unstructured":"Faniran AO, Peat JK, Woolcock AJ: Persistent cough: is it asthma?. Arch Dis Child. 1998, 79: 411-414. 10.1136\/adc.79.5.411.","journal-title":"Arch Dis Child"},{"key":"105_CR24","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1046\/j.1440-1754.2002.00045.x","volume":"38","author":"F Thomson","year":"2002","unstructured":"Thomson F, Masters IB, Chang AB: Persistent cough in children-overuse of medications. J Paediatr Child Health. 2002, 38: 578-581. 10.1046\/j.1440-1754.2002.00045.x.","journal-title":"J Paediatr Child Health"},{"key":"105_CR25","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1136\/bmj.288.6431.1647","volume":"288","author":"A Charlton","year":"1984","unstructured":"Charlton A: Children coughs related to parental smoking. Br Med J (Clin Res Ed). 1984, 288: 1647-1649. 10.1136\/bmj.288.6431.1647.","journal-title":"Br Med J (Clin Res Ed)"},{"key":"105_CR26","doi-asserted-by":"publisher","first-page":"l142","DOI":"10.1378\/chest.129.5.1142","volume":"129","author":"NH Kwon","year":"2006","unstructured":"Kwon NH, Oh MJ, Min TH, Lee BJ, Choi DC: Causes andclinical features of subacute cough. Chest. 2006, 129: l142-l1147.","journal-title":"Chest"},{"key":"105_CR27","first-page":"413","volume":"123","author":"RS Irwin","year":"1981","unstructured":"Irwin RS, Corrao WM, Pratter MR: Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specifi c therapy. Am Rev Respir Dis. 1981, 123: 413-417.","journal-title":"Am Rev Respir Dis"},{"key":"105_CR28","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1164\/ajrccm\/141.3.640","volume":"141","author":"RS Irwin","year":"1990","unstructured":"Irwin RS, Curley FJ, Frech CL: Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Am Rev Respir Dis. 1990, 141: 640-647. 10.1164\/ajrccm\/141.3.640.","journal-title":"Am Rev Respir Dis"},{"key":"105_CR29","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1001\/archinte.1996.00440090103010","volume":"156","author":"CJ Mello","year":"1996","unstructured":"Mello CJ, Irwin RS, Curley FJ: Predictive values of the character, timing, and complications of chronic cough in diagnosing its cause. Arch Intern Med. 1996, 156: 997-1003. 10.1001\/archinte.1996.00440090103010.","journal-title":"Arch Intern Med"},{"key":"105_CR30","doi-asserted-by":"publisher","first-page":"2701","DOI":"10.1001\/archinte.1989.00390120061012","volume":"149","author":"GR Gibson","year":"1989","unstructured":"Gibson GR: Enalapril-induced cough. Arch Intern Med. 1989, 149: 2701-2703. 10.1001\/archinte.1989.00390120061012.","journal-title":"Arch Intern Med"},{"issue":"2","key":"105_CR31","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1164\/ajrccm.160.2.9810100","volume":"160","author":"CE Brightling","year":"1999","unstructured":"Brightling CE, Ward R, Goh KL, Wardlaw AJ, Pavord ID: Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med. 1999, 160 (2): 406-410. 10.1164\/ajrccm.160.2.9810100.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR32","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1164\/ajrccm.156.1.9605044","volume":"156","author":"IK Carney","year":"1997","unstructured":"Carney IK, Gibson PG, Murree-Allen K, Saltos N, Olson LG, Hensley MJ: A systematic evaluation of mechanisms in chronic cough. Am J Respir Crit Care Med. 1997, 156: 211-216. 10.1164\/ajrccm.156.1.9605044.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR33","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3904\/kjim.2002.17.1.31","volume":"17","author":"JH Joo","year":"2002","unstructured":"Joo JH, Park SJ, Park SW, Lee JH, Kim DJ, Uh ST, Kim YH, Park CS: Clinical features of eosinophilic bronchitis. Korean J Intern Med. 2002, 17: 31-37.","journal-title":"Korean J Intern Med"},{"key":"105_CR34","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1053\/rmed.2003.1503","volume":"97","author":"SO Ayik","year":"2003","unstructured":"Ayik SO, Basoglu OK, Erdinc M, Bor S, Veral A, Bilgen C: Eosinophilic bronchitis as a cause of chronic cough. Respir Med. 2003, 97: 695-701. 10.1053\/rmed.2003.1503.","journal-title":"Respir Med"},{"key":"105_CR35","first-page":"96","volume":"29","author":"KF Lai","year":"2006","unstructured":"Lai KF, Chen RC, Liu CL, Luo W, Zhong SQ, He MZ, Li DR, Zhong NS: Etiology and a diagnostic protocol for patients with chronic cough. Chin J Tuberc Respir Dis. 2006, 29: 96-99.","journal-title":"Chin J Tuberc Respir Dis"},{"key":"105_CR36","first-page":"422","volume":"32","author":"GL Lu","year":"2006","unstructured":"Lu GL, Lin JT: The spectrum and clinical features of causes for chronic cough. Chin J Tuberc Respir Dis. 2006, 32: 422-425.","journal-title":"Chin J Tuberc Respir Dis"},{"key":"105_CR37","first-page":"62","volume":"26","author":"ZM Yang","year":"2005","unstructured":"Yang ZM, Qiu ZM, Lv HJ, Wei WL, Wang L, Liu RL: A prospective study on the causes of chronic cough. J Tongji Univ. 2005, 26: 62-64.","journal-title":"J Tongji Univ"},{"key":"105_CR38","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1183\/09031936.04.00027804","volume":"24","author":"AH Morice","year":"2004","unstructured":"Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J, O'Connell F, Geppetti P, Gronke L, De Jongste J, Belvisi M, Dicpinigaitis P, Fischer A, McGarvey L, Fokkens WJ, Kastelik J: The diagnosis and management of chronic cough. Eur Respir J. 2004, 24: 481-492. 10.1183\/09031936.04.00027804.","journal-title":"Eur Respir J"},{"key":"105_CR39","first-page":"738","volume":"28","author":"Asthma workgroup of Chinese society of respiratory diseases(CSRD)","year":"2005","unstructured":"Asthma workgroup of Chinese society of respiratory diseases(CSRD): Chinese medical association :the Chinese national guidelines on diagnosis and management of cough(protocal). Chin J Tuberc Respir Dis. 2005, 28: 738-744.","journal-title":"Chin J Tuberc Respir Dis"},{"key":"105_CR40","doi-asserted-by":"publisher","first-page":"1S","DOI":"10.1378\/chest.129.1_suppl.1S","volume":"129","author":"S Richard","year":"2006","unstructured":"Richard S, Irwin RS, Michael H, et al: American college of chest physicians (ACCP): diagnosis and management of cough executive summary ACCP evidence-based clinical practice guidelines. Chest. 2006, 129: 1S-23S. 10.1378\/chest.129.1_suppl.1S.","journal-title":"Chest"},{"key":"105_CR41","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1440-1843.2005.00686.x","volume":"10","author":"M Fujimura","year":"2005","unstructured":"Fujimura M, Abo M, Ogawa H, Nishi K, Kibe Y, Hirose T, Nakatsumi Y, Iwasa K: Importance of atopic cough, cough variant asthma and sinobronchial syndrome as causes of chronic cough in the Hokuriku area of Japan. Respirology. 2005, 10: 201-207. 10.1111\/j.1440-1843.2005.00686.x.","journal-title":"Respirology"},{"issue":"8","key":"105_CR42","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1016\/j.cgh.2012.02.028","volume":"10","author":"J Dent","year":"2012","unstructured":"Dent J, Becher A, Sung J, Zou D, Agr\u00e9us L, Bazzoli F: Systemic review: patterns of reflux-induced symptoms and esophageal endoscopic findings in large-scal survey. Clin Gastroenterol Hepatol. 2012, 10 (8): 863-873. 10.1016\/j.cgh.2012.02.028.","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"105_CR43","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1164\/rccm.200506-901OC","volume":"173","author":"LM Butler","year":"2006","unstructured":"Butler LM, Koh WP, Lee HP, Tseng M, Yu MC, London SJ: Prospective study of dietary patterns and persistent cough with phlegm among Chinese Singaporeans. Am J Respir Crit Care Med. 2006, 173 (3): 264-270. 10.1164\/rccm.200506-901OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR44","doi-asserted-by":"publisher","first-page":"447","DOI":"10.2169\/internalmedicine.31.447","volume":"31","author":"M Fujimura","year":"1992","unstructured":"Fujimura M, Sakamoto S, Matsuda T: Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness. Intern Med. 1992, 31: 447-452. 10.2169\/internalmedicine.31.447.","journal-title":"Intern Med"},{"issue":"suppl","key":"105_CR45","first-page":"S160","volume":"11","author":"JR Society","year":"2006","unstructured":"Society JR: Prolonged and chronic cough. Respirology. 2006, 11 (suppl): S160-S174.","journal-title":"Respirology"},{"key":"105_CR46","first-page":"862","volume":"33","author":"SY Si","year":"2010","unstructured":"Si SY, Peng QF, Shi X, Kong LF: Distribution of causes and clinical features of chronic cough in Shenyang and its surrounding districts. Chin J Tuberc Respir Dis. 2010, 33: 862-863.","journal-title":"Chin J Tuberc Respir Dis"},{"key":"105_CR47","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1378\/chest.127.5.1710","volume":"127","author":"RA Haque","year":"2005","unstructured":"Haque RA, Usmani OS, Barnes PJ: Chronic idiopathic cough: a discrete clinical entity?. Chest. 2005, 127: 1710-1713. 10.1378\/chest.127.5.1710.","journal-title":"Chest"},{"key":"105_CR48","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3109\/07853898909149233","volume":"21","author":"H Puolijoki","year":"1989","unstructured":"Puolijoki H, Lahdensuo A: Causes of prolonged cough in patients referred to a chest clinic. Ann Med. 1989, 21: 425-427. 10.3109\/07853898909149233.","journal-title":"Ann Med"},{"issue":"10","key":"105_CR49","doi-asserted-by":"publisher","first-page":"977","DOI":"10.7326\/0003-4819-119-10-199311150-00003","volume":"119","author":"MR Pratter","year":"1993","unstructured":"Pratter MR, Bartter T, Akers S, DuBois J: An algorithmic approach to chronic cough. Ann Intern Med. 1993, 119 (10): 977-983. 10.7326\/0003-4819-119-10-199311150-00003.","journal-title":"Ann Intern Med"},{"issue":"Suppl 1","key":"105_CR50","doi-asserted-by":"publisher","first-page":"S87","DOI":"10.1007\/s00408-009-9185-z","volume":"188","author":"AH Morice","year":"2010","unstructured":"Morice AH: The cough hypersensitivity syndrome: a novel paradigm for understanding cough. Lung. 2010, 188 (Suppl 1): S87-S90.","journal-title":"Lung"},{"key":"105_CR51","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.pupt.2011.01.012","volume":"24","author":"KF Chung","year":"2011","unstructured":"Chung KF: Chronic 'cough hypersensitivity syndrome': a more precise label for chronic cough. Pulm Pharmacol Ther. 2011, 24: 267-271. 10.1016\/j.pupt.2011.01.012.","journal-title":"Pulm Pharmacol Ther"},{"key":"105_CR52","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1001\/archinte.1996.00440090103010","volume":"156","author":"RH Poe","year":"1996","unstructured":"Poe RH, Harder RV, Israel RH: Chronic persistent cough. Expericence in diagnosis and outcome using an anatomic diagnosing its cause. Arch Intern Med. 1996, 156: 997-1003. 10.1001\/archinte.1996.00440090103010.","journal-title":"Arch Intern Med"},{"key":"105_CR53","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1164\/rccm.200308-1092OC","volume":"169","author":"SS Birring","year":"2004","unstructured":"Birring SS, Parker D, Brightling CE, Bradding P, Wardlaw AJ, Pavord ID: Induced sputum inflammatory mediator concentrations in chronic cough. Am J Respir Crit Care Med. 2004, 169: 15-19. 10.1164\/rccm.200308-1092OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR54","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1183\/09031936.05.00140803","volume":"25","author":"JA Kastelik","year":"2005","unstructured":"Kastelik JA, Aziz I, Ojoo JC, Thompson RH, Redington AE, Morice AH: Investigation and management of chronic cough using a probability-based algorithm. Eur Respir J. 2005, 25: 235-243. 10.1183\/09031936.05.00140803.","journal-title":"Eur Respir J"},{"key":"105_CR55","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1159\/000142942","volume":"77","author":"W Wei","year":"2009","unstructured":"Wei W, Yu L, Lu H, Wang L, Shi C, Ma W, Huang Y, Qiu Z: Comparison of Cause Distribution between Elderly and Non-Elderly Patients with Chronic Cough. Respiration. 2009, 77: 259-264. 10.1159\/000142942.","journal-title":"Respiration"},{"issue":"1 Suppl","key":"105_CR56","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1378\/chest.129.1_suppl.260S","volume":"129","author":"GWB ChangAB","year":"2006","unstructured":"ChangAB GWB: Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-hased clinical practice, idelines. Chest. 2006, 129 (1 Suppl): 260-283.","journal-title":"Chest"},{"issue":"5","key":"105_CR57","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1378\/chest.129.5.1132","volume":"129","author":"JM Marchant","year":"2006","unstructured":"Marchant JM, Masters IB, Taylor SM, Cox NC, Seymour GJ, Chang AB: Evaluation and outcome of young children with chronic cough. Chest. 2006, 129 (5): 1132-1141B. 10.1378\/chest.129.5.1132.","journal-title":"Chest"},{"issue":"3","key":"105_CR58","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1378\/chest.09-0649","volume":"136","author":"V Khoshoo","year":"2009","unstructured":"Khoshoo V, Edell D, Mohnot S, Haydel R, Saturno E, Kobernick A: Associated factors in children with chronic cough. Chest. 2009, 136 (3): 811-815. 10.1378\/chest.09-0649.","journal-title":"Chest"},{"issue":"2","key":"105_CR59","first-page":"109","volume":"21","author":"SY Zhao","year":"2006","unstructured":"Zhao SY, Ren YX, Jiang ZF: Causes and diagnostic procedure of 50 children with chronic solitary cough. Chin J Pract Pediat. 2006, 21 (2): 109-111.","journal-title":"Chin J Pract Pediat"},{"key":"105_CR60","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1093\/pubmed\/fdn003","volume":"30","author":"AJ Elliot","year":"2008","unstructured":"Elliot AJ, Cross KW, Fleming DM: Acute respiratory infections and winter pressures on hospital admissions in England and Wales 1990\u20132005. J Public Health (Oxf). 2008, 30: 91-98. 10.1093\/pubmed\/fdn003.","journal-title":"J Public Health (Oxf)"},{"key":"105_CR61","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1164\/rccm.200901-0122OC","volume":"180","author":"MM Patel","year":"2009","unstructured":"Patel MM, Hoepner L, Garfi Nkel R, Chillrud S, Reyes A, Quinn JW, Perera F, Miller RL: Ambient metals, elemental carbon, and wheeze and cough in New York city children through 24 months of age. Am J Respir Crit Care Med. 2009, 180: 1107-1113. 10.1164\/rccm.200901-0122OC.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR62","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1201\/b13996-9","volume-title":"Medical treatment of gastroesophageal reflux disease and airway disease","author":"MS Kavuru","year":"1999","unstructured":"Kavuru MS, Richter JE: Gastroesophageal reflux disease and airway disease. Medical treatment of gastroesophageal reflux disease and airway disease. Edited by: Stein M. 1999, New York: Marcel Dekker, 179-207."},{"key":"105_CR63","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1378\/chest.121.4.1132","volume":"121","author":"RS Irwin","year":"2002","unstructured":"Irwin RS, Zawacki JK, Wilson MM, French CT, Callery MP: Chronic cough due to gastroesophageal reflux disease: failure to resolve despite total\/near-total elimination of esophageal acid. Chest. 2002, 121: 1132-1140. 10.1378\/chest.121.4.1132.","journal-title":"Chest"},{"key":"105_CR64","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1164\/ajrccm.157.4.9609008","volume":"157","author":"S Vedal","year":"1998","unstructured":"Vedal S, Petkau J, White R, Blair J: Acute effects of ambient inhalable particles in asthmatic and nonasthmatic children. Am J Respir Crit Care Med. 1998, 157: 1034-1043. 10.1164\/ajrccm.157.4.9609008.","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"105_CR65","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1016\/j.rmed.2010.07.018","volume":"104","author":"G Pan","year":"2010","unstructured":"Pan G, Zhang S, Feng Y, Takahashi K, Kagawa J, Yu L, Wang P, Liu M, Liu Q, Hou S, Pan B, Li J: Air pollution and children's respiratory symptoms in six cities of Northern China. Respir Med. 2010, 104 (12): 1903-1911. 10.1016\/j.rmed.2010.07.018.","journal-title":"Respir Med"},{"key":"105_CR66","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1093\/aje\/kwj338","volume":"164","author":"L Bayer-Oglesby","year":"2006","unstructured":"Bayer-Oglesby L, Schindler C, Hazenkamp-von Arx ME, Braun-Fahrl\u00e4nder C, Keidel D, Rapp R, K\u00fcnzli N, Braendli O, Burdet L, Sally Liu LJ, Leuenberger P, Ackermann-Liebrich U: SAPALDIA Team: Living near main streets and respiratory symptoms in adults. Am J Epidemiol. 2006, 164: 1190-1198. 10.1093\/aje\/kwj338.","journal-title":"Am J Epidemiol"},{"key":"105_CR67","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1053\/rmed.2001.1129","volume":"95","author":"P Montnemery","year":"2001","unstructured":"Montnemery P, Bengtson P, Elliot A, Lindholm LH, Nyberg P, Lofdahl CG: Prevalence of obstructive lung diseases and respiratory symptoms in relation to living environment and socio-economic group. Respir Med. 2001, 95: 744-752. 10.1053\/rmed.2001.1129.","journal-title":"Respir Med"},{"key":"105_CR68","first-page":"1034","volume":"3","author":"G Viegi","year":"1999","unstructured":"Viegi G, Pedreschi M, Baldacci S, Chiaffi L, Pistelli F, Modena P, Vellutini M, Di Pede F, Carrozzi L: Prevalence rates of respiratory symptoms and diseases in general population samples of North and Certral Italy. Int J Tuberc Lung Dis. 1999, 3: 1034-1042.","journal-title":"Int J Tuberc Lung Dis"},{"issue":"3","key":"105_CR69","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1080\/09603120903511119","volume":"20","author":"HK Lai","year":"2010","unstructured":"Lai HK, Ho SY, Wong CM, Mak KK, Lo WS, Lam TH: Exposure to particulate air pollution at different living locations and respiratory symptoms in Hong Kong\u2013an application of satellite information. Int J Environ Health Res. 2010, 20 (3): 219-230. 10.1080\/09603120903511119.","journal-title":"Int J Environ Health Res"},{"key":"105_CR70","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1183\/09031936.01.00096801","volume":"18","author":"U Gehring","year":"2001","unstructured":"Gehring U, Heinrich J, Jacob B, Richter K, Fahlbusch B, Schlenvoigt G, Bischof W, Wichmann HE: Respiratory symptoms in relations to indoor exposure to mite and cat allengens and endotoxins. Indoor factors and Genetics in Asthma(INGA)Study Group. Eur Respir J. 2001, 18: 555-563. 10.1183\/09031936.01.00096801.","journal-title":"Eur Respir J"},{"issue":"5","key":"105_CR71","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.anai.2011.02.004","volume":"105","author":"I Bobolea","year":"2011","unstructured":"Bobolea I, Barranco P, Sastre B, Fern\u00e1ndez-Nieto M, del Pozo V, Quirce S: Seasonal eosinophilic bronchitis due to allergy to Cupressus arizonica pollen. Ann Allergy Asthma Immunol. 2011, 105 (5): 448-449.","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"12","key":"105_CR72","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1111\/j.1398-9995.2005.00920.x","volume":"60","author":"MR Yacoub","year":"2005","unstructured":"Yacoub MR, Malo JL, Labrecque M, Cartier A, Lemi\u00e8re C: Occupational eosinophilic bronchitis. Allergy. 2005, 60 (12): 1542-1544.","journal-title":"Allergy"},{"issue":"4","key":"105_CR73","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.iac.2011.07.005","volume":"31","author":"A Cartier","year":"2011","unstructured":"Cartier A, Sastre J: Clinical assessment of occupational asthma and its differential diagnosis. Immunol Allergy Clin North Am. 2011, 31 (4): 717-728. 10.1016\/j.iac.2011.07.005.","journal-title":"Immunol Allergy Clin North Am"},{"key":"105_CR74","doi-asserted-by":"publisher","first-page":"133S","DOI":"10.1378\/chest.114.2_Supplement.133S","volume":"114","author":"RS Irwin","year":"1998","unstructured":"Irwin RS, Boulet LP, Cloutier MM, Fuller R, Gold PM, Hoffstein V, Ing AJ, McCool FD, O'Byrne P, Poe RH, Prakash UB, Pratter MR, Rubin BK: Managing cough as a defense mechanism and as a symptom: a consensus panel report of the American College of Chest Physicians. Chest. 1998, 114: 133S-181S. 10.1378\/chest.114.2_Supplement.133S.","journal-title":"Chest"},{"key":"105_CR75","doi-asserted-by":"publisher","first-page":"2701","DOI":"10.1001\/archinte.1989.00390120061012","volume":"149","author":"GR Gibson","year":"1989","unstructured":"Gibson GR: Enalapril-induced cough. Arch Intern Med. 1989, 149: 2701-2703. 10.1001\/archinte.1989.00390120061012.","journal-title":"Arch Intern Med"},{"key":"105_CR76","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3109\/02770909409089488","volume":"31","author":"M Fujimura","year":"1994","unstructured":"Fujimura M, Kamio Y, Hashimoto T, Matsuda T: Cough receptor sensitivity and bronchial responsiveness in patients with only chronic nonproductive cough. in view of effect of bronchodilator therapy. J Asthma. 1994, 31: 463-472. 10.3109\/02770909409089488.","journal-title":"J Asthma"},{"key":"105_CR77","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1183\/09031936.96.09081624","volume":"9","author":"M Fujimura","year":"1996","unstructured":"Fujimura M, Kasahara K, Kamio Y, Naruse M, Hashimoto T, Matsuda T: Female gender as a determinant of cough threshold to inhaled capsaicin. Eur Respir J. 1996, 9: 1624-1626. 10.1183\/09031936.96.09081624.","journal-title":"Eur Respir J"},{"key":"105_CR78","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1164\/rccm.2109061","volume":"166","author":"JA Kastelik","year":"2002","unstructured":"Kastelik JA, Thompson RH, Aziz I, Ojoo JC, Redington AE, Morice AH: Sex-related differences in cough reflex sensitivity in patients with chronic cough. Am J Respir Crit Care Med. 2002, 166: 961-964. 10.1164\/rccm.2109061.","journal-title":"Am J Respir Crit Care Med"},{"key":"105_CR79","doi-asserted-by":"publisher","first-page":"54S","DOI":"10.1378\/chest.129.1_suppl.54S","volume":"129","author":"RS Irwin","year":"2006","unstructured":"Irwin RS: Complications of cough :ACCP evidence-based clinical practice guidelines. Chest. 2006, 129: 54S-58S. 10.1378\/chest.129.1_suppl.54S.","journal-title":"Chest"},{"key":"105_CR80","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1378\/chest.125.2.482","volume":"125","author":"CT French","year":"2004","unstructured":"French CT, Fletcher KE, Irwin RS: Gender differences in health-related quality of life in patients complaining of chronic cough. Chest. 2004, 125: 482-488. 10.1378\/chest.125.2.482.","journal-title":"Chest"},{"issue":"15","key":"105_CR81","first-page":"391","volume":"158","author":"CZ Yang","year":"2010","unstructured":"Yang CZ, Chen RC, Li BK, Wang FX, Lai KF: Survey of quality of life and incontinence in female patients with chronic cough. Int J Respir. 2010, 158 (15): 391-394.","journal-title":"Int J Respir"},{"key":"105_CR82","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1001\/archinte.158.15.1657","volume":"158","author":"CL French","year":"1998","unstructured":"French CL, Irwin RS, Curley FJ, Krikorian CJ: Impact of chronic cough on quality of life. Arch Intern Med. 1998, 158: 1657-1661. 10.1001\/archinte.158.15.1657.","journal-title":"Arch Intern Med"},{"key":"105_CR83","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1136\/thorax.58.4.339","volume":"58","author":"SS Birring","year":"2003","unstructured":"Birring SS, Prudon B, Carr AJ, Singh SJ, Morgan MD, Pavord ID: Development of a symptom specific health status measure for patients with chronic cough: Leicester cough questionnaire (LCQ). Thorax. 2003, 58: 339-343. 10.1136\/thorax.58.4.339.","journal-title":"Thorax"},{"issue":"4","key":"105_CR84","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1111\/j.1398-9995.2005.00743.x","volume":"60","author":"I Baiardini","year":"2005","unstructured":"Baiardini I, Braido F, Fassio O, Tarantini F, Pasquali M, Tarchino F, Berlendis A, Canonica GW: A new tool to assess and monitor the burden of chronic cough on quality of life: chronic cough impact questionnaire. Allergy. 2005, 60 (4): 482-488. 10.1111\/j.1398-9995.2005.00743.x.","journal-title":"Allergy"},{"key":"105_CR85","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1378\/chest.130.6.1839","volume":"130","author":"PV Dicpinigaitis","year":"2006","unstructured":"Dicpinigaitis PV, Tso R, Banauch G: Prevalence of depressive symptoms among patients with chronic cough. Chest. 2006, 130: 1839-1843. 10.1378\/chest.130.6.1839.","journal-title":"Chest"},{"key":"105_CR86","first-page":"326","volume":"31","author":"KF Lai","year":"2011","unstructured":"Lai KF, Li BK, Wang FX, Zhong NS: Quality-of-life questionnaire in patients with chronic cough. Int J Respir. 2011, 31: 326-328.","journal-title":"Int J Respir"}],"container-title":["Cough"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1745-9974-9-18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,2]],"date-time":"2023-07-02T23:27:50Z","timestamp":1688340470000},"score":1,"resource":{"primary":{"URL":"https:\/\/coughjournal.biomedcentral.com\/articles\/10.1186\/1745-9974-9-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,8]]},"references-count":86,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["105"],"URL":"https:\/\/doi.org\/10.1186\/1745-9974-9-18","relation":{},"ISSN":["1745-9974"],"issn-type":[{"value":"1745-9974","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,8]]},"assertion":[{"value":"25 January 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"18"}}