{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:08:59Z","timestamp":1770836939545,"version":"3.50.1"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diagn Pathol"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Ichthyosis uteri is a rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. Though the condition often is considered as benign, anaplastic and dysplastic changes have been reported. We describe herein a rare case of low-grade squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri with dysplasia. The cervix showed moderate to severe dysplastic changes while the right fallopian tube showed extensive squamous metaplasia with dysplastic changes. We conclude that squamous cell carcinoma could develop into pre-existing ichthyosis uteri.<\/jats:p>","DOI":"10.1186\/1746-1596-3-4","type":"journal-article","created":{"date-parts":[[2008,1,31]],"date-time":"2008-01-31T07:15:23Z","timestamp":1201763723000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Does \"ichthyosis uteri\" have malignant potential? : A case report of squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri"],"prefix":"10.1186","volume":"3","author":[{"given":"Kanchan","family":"Murhekar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urmila","family":"Majhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Sridevi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Rajkumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,1,31]]},"reference":[{"key":"126_CR1","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/0002-9378(62)90060-1","volume":"84","author":"WT Patton","year":"1962","unstructured":"Patton WT, Squares GV: Ichthyosis uteri. A case report. Am J Obstet Gynecol. 1962, 84: 858-860.","journal-title":"Am J Obstet Gynecol"},{"key":"126_CR2","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1097\/00004347-199707000-00014","volume":"16","author":"Mr Pins","year":"1997","unstructured":"Pins Mr, Young RH, Crum CP, Leach IH, Scully RE: Cervical squamous cell carconoma in situ with intraepithelial extension to the upper genital tract and invasion of tubes and ovaries: report of a case with human papilloma virus analysis. Int J Gynecol Pathol. 1997, 16: 272-278.","journal-title":"Int J Gynecol Pathol"},{"key":"126_CR3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1746-1596-1-8","volume":"1","author":"O Fadare","year":"2006","unstructured":"Fadare O: Dysplastic Ichthyosis Uteri-like changes of the entire endometrium associated with a squamous cell carcinoma of the uterine cervix. Diagnostic Pathology. 2006, 1: 8-10.1186\/1746-1596-1-8.","journal-title":"Diagnostic Pathology"},{"key":"126_CR4","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.5858\/2005-129-e124-IUACRA","volume":"129","author":"C Bewtra","year":"2005","unstructured":"Bewtra C, Xie QM, Hunter WJ, Jurgensen W: Ichthyosis uteri: a case report and review of literature. Arch Pathol Lab Med. 2005, 129: e124-125.","journal-title":"Arch Pathol Lab Med"},{"key":"126_CR5","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1055\/s-2008-1035908","volume":"46","author":"V Heckeroth","year":"1986","unstructured":"Heckeroth V, Ziegler HK: Ichthyosis uteri. Case report on a rate clinical entity. Geburtshilfe Frauenheilkd. 1986, 46: 248-249.","journal-title":"Geburtshilfe Frauenheilkd"}],"container-title":["Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-1596-3-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T03:49:32Z","timestamp":1630468172000},"score":1,"resource":{"primary":{"URL":"https:\/\/diagnosticpathology.biomedcentral.com\/articles\/10.1186\/1746-1596-3-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,31]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["126"],"URL":"https:\/\/doi.org\/10.1186\/1746-1596-3-4","relation":{},"ISSN":["1746-1596"],"issn-type":[{"value":"1746-1596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,31]]},"assertion":[{"value":"22 November 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"4"}}