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Moreover, FISH and molecular genetic study confirmed concomitant MYC translocations and t(14;18) in the high-grade component, thereby suggesting the transformation of atypical Burkitt's lymphoma from an undiagnosed antecedent follicular lymphoma. The disease followed an aggressive clinical course, terminating in refractory disease 13 months after diagnosis. This is followed by a comprehensive review of the literature on lymphoma transformations from underlying follicular lymphoma after acquisition of MYC translocation, using Burkitt's lymphoma, follicular lymphoma, transformation and MYC translocations as keywords.<\/jats:p>","DOI":"10.1186\/1746-1596-6-63","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T15:55:35Z","timestamp":1310140535000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Atypical burkitt's lymphoma transforming from follicular lymphoma"],"prefix":"10.1186","volume":"6","author":[{"given":"Yu Y","family":"Hwang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Loong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lap P","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chor S","family":"Chim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,7,8]]},"reference":[{"key":"435_CR1","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1002\/j.1460-2075.1993.tb06189.x","volume":"12","author":"R Kuppers","year":"1993","unstructured":"Kuppers R, Zhao M, Hansmann ML, Rajewsky K: Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. 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