{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T23:31:22Z","timestamp":1780702282978,"version":"3.54.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,2,8]],"date-time":"2007-02-08T00:00:00Z","timestamp":1170892800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head Face Med"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1186\/1746-160x-3-10","type":"journal-article","created":{"date-parts":[[2007,2,8]],"date-time":"2007-02-08T19:09:10Z","timestamp":1170961750000},"source":"Crossref","is-referenced-by-count":29,"title":["The spectrum of Apert syndrome: phenotype, particularities in orthodontic treatment, and characteristics of orthognathic surgery"],"prefix":"10.1186","volume":"3","author":[{"given":"Ariane","family":"Hohoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Joos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Ehmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Stamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,2,8]]},"reference":[{"key":"72_CR1","first-page":"532","volume":"100","author":"MM Cohen","year":"1997","unstructured":"Cohen MM: Apert syndrome, not Apert's syndrome: Apert neither had nor owned the syndrome that bears his name. Plast Reconstr Surg. 1997, 100: 532-533.","journal-title":"Plast Reconstr Surg"},{"key":"72_CR2","first-page":"238","volume":"45","author":"SW Wheaton","year":"1894","unstructured":"Wheaton SW: Two specimens of congenital cranial deformity in infants associated with fusion of fingers and toes. Trans Pathol Soc Lond. 1894, 45: 238-241.","journal-title":"Trans Pathol Soc Lond"},{"key":"72_CR3","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1002\/(SICI)1096-8628(19971112)72:4<394::AID-AJMG4>3.0.CO;2-R","volume":"72","author":"MM Tolarova","year":"1997","unstructured":"Tolarova MM, Harris JA, Ordway DE, Vargervik K: Birth prevalence, mutation rate, sex ratio, parents' age, and ethnicity in Apert syndrome. Am J Med Genet. 1997, 72: 394-398. 10.1002\/(SICI)1096-8628(19971112)72:4<394::AID-AJMG4>3.0.CO;2-R.","journal-title":"Am J Med Genet"},{"key":"72_CR4","first-page":"667","volume":"51","author":"I Arroyo Carrera","year":"1999","unstructured":"Arroyo Carrera I, Martinez-Frias ML, Marco Perez JJ, Paisan Grisolia L, Cardenes Rodriguez A, Nieto Conde C, Felix Rodriguez V, Egues Jimeno JJ, Morales Fernandez MC, Gomez-Ullate Vergara J, Pardo Romero M, Penas Valiente A, Olivan del Cacho MJ, Lara Palma A: Apert syndrome: clinico-epidemiological analysis of a series of consecutive cases in Spain. An Esp Pediatr. 1999, 51: 667-672.","journal-title":"An Esp Pediatr"},{"key":"72_CR5","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/01.PRS.0000146703.08958.95","volume":"115","author":"OA Ibrahimi","year":"2005","unstructured":"Ibrahimi OA, Chiu ES, McCarthy JG, Mohammadi M: Understanding the molecular basis of Apert syndrome. Plast Reconstr Surg. 2005, 115: 264-270.","journal-title":"Plast Reconstr Surg"},{"key":"72_CR6","first-page":"423","volume":"30","author":"RP Paravatty","year":"1999","unstructured":"Paravatty RP, Ahsan A, Sebastian BT, Pai KM, Dayal PK: Apert syndrome: a case report with discussion of craniofacial features. Quintessence Int. 1999, 30: 423-426.","journal-title":"Quintessence Int"},{"key":"72_CR7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0094-1298(20)30823-3","volume":"18","author":"NF Ferraro","year":"1991","unstructured":"Ferraro NF: Dental, orthodontic, and oral\/maxillofacial evaluation and treatment in Apert syndrome. Clin Plast Surg. 1991, 18: 291-307.","journal-title":"Clin Plast Surg"},{"key":"72_CR8","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/s003810000320","volume":"16","author":"D Renier","year":"2000","unstructured":"Renier D, Lajeunie E, Arnaud E, Marchac D: Management of craniosynostoses. Childs Nerv Syst. 2000, 16: 645-658. 10.1007\/s003810000320.","journal-title":"Childs Nerv Syst"},{"key":"72_CR9","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1097\/01.SCS.0000157201.81438.31","volume":"16","author":"MC Meazzini","year":"2005","unstructured":"Meazzini MC, Mazzoleni F, Caronni E, Bozzetti A: LeFort III advancement osteotomy in the growing child affected by Crouzon's and Apert's syndromes: presurgical and postsurgical growth. J Craniofac Surg. 2005, 16: 369-377. 10.1097\/01.SCS.0000157201.81438.31.","journal-title":"J Craniofac Surg"},{"key":"72_CR10","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1080\/000163598428275","volume":"56","author":"S Kreiborg","year":"1998","unstructured":"Kreiborg S, Cohen MM: Is craniofacial morphology in Apert and Crouzon syndromes the same?. Acta Odontol Scand. 1998, 56: 339-341. 10.1080\/000163598428275.","journal-title":"Acta Odontol Scand"},{"key":"72_CR11","first-page":"1","volume":"19","author":"S Kreiborg","year":"1999","unstructured":"Kreiborg S, Aduss H, Cohen MM: Cephalometric study of the Apert syndrome in adolescence and adulthood. J Craniofac Genet Dev Biol. 1999, 19: 1-11.","journal-title":"J Craniofac Genet Dev Biol"},{"key":"72_CR12","first-page":"118","volume":"20","author":"P Batra","year":"2002","unstructured":"Batra P, Duggal R, Parkash H: Dentofacial characteristics in Apert syndrome: a case report. J Indian Soc Pedod Prev Dent. 2002, 20: 118-123.","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"72_CR13","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S0901-5027(96)80011-7","volume":"25","author":"MM Cohen","year":"1996","unstructured":"Cohen MM, Kreiborg S: A clinical study of the craniofacial features in Apert syndrome. Int J Oral Maxillofac Surg. 1996, 25: 45-53. 10.1016\/S0901-5027(96)80011-7.","journal-title":"Int J Oral Maxillofac Surg"},{"key":"72_CR14","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1597\/1545-1569(1997)034<0117:DDIAS>2.3.CO;2","volume":"34","author":"S Kaloust","year":"1997","unstructured":"Kaloust S, Ishii K, Vargervik K: Dental development in Apert syndrome. Cleft Palate Craniofac J. 1997, 34: 117-121. 10.1597\/1545-1569(1997)034<0117:DDIAS>2.3.CO;2.","journal-title":"Cleft Palate Craniofac J"},{"key":"72_CR15","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1746-160X-1-8","volume":"1","author":"A Hohoff","year":"2005","unstructured":"Hohoff A, Rabe H, Ehmer U, Harms E: Palatal development of preterm and low birthweight infants compared to term infants \u2013 What do we know? Part 1: The palate of the term newborn. Head Face Med. 2005, 1: 8-10.1186\/1746-160X-1-8.","journal-title":"Head Face Med"},{"key":"72_CR16","first-page":"41","volume":"12","author":"S Kreiborg","year":"1992","unstructured":"Kreiborg S, Cohen MM: The oral manifestations of Apert syndrome. J Craniofac Genet Dev Biol. 1992, 12: 41-48.","journal-title":"J Craniofac Genet Dev Biol"},{"key":"72_CR17","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1007\/BF00366159","volume":"12","author":"DA Bruce","year":"1996","unstructured":"Bruce DA: Consensus: craniofacial synostoses. Apert and Crouzon syndromes. Childs Nerv Syst. 1996, 12: 734-736. 10.1007\/BF00366159.","journal-title":"Childs Nerv Syst"},{"key":"72_CR18","doi-asserted-by":"publisher","first-page":"443","DOI":"10.3171\/jns.1999.90.3.0443","volume":"90","author":"E Lajeunie","year":"1999","unstructured":"Lajeunie E, Cameron R, El Ghouzzi V, de Parseval N, Journeau P, Gonzales M, Delezoide AL, Bonaventure J, Le Merrer M, Renier D: Clinical variability in patients with Apert's syndrome. J Neurosurg. 1999, 90: 443-447.","journal-title":"J Neurosurg"},{"key":"72_CR19","unstructured":"Online Mendelian Inheritance in Man. [ http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?db=OMIM ]"},{"key":"72_CR20","first-page":"91","volume":"98","author":"D Wiechmann","year":"1997","unstructured":"Wiechmann D, Ehmer U, Joos U, Dorr-Neudeck K: A prefabricated, calibrated double-base procedure-KDMMS. For the simulation and 3-dimensional planning using an articulator in orthognathic surgery. Rev Stomatol Chir Maxillofac. 1997, 98: 91-95.","journal-title":"Rev Stomatol Chir Maxillofac"},{"key":"72_CR21","first-page":"353","volume-title":"Trans Eur Orthod Soc","author":"PJ Gugny","year":"1973","unstructured":"Gugny PJ: Orthodontic treatment of a case of Apert's syndrome first steps towards surgical correction. Trans Eur Orthod Soc. 1973, 353-359."},{"key":"72_CR22","first-page":"565","volume":"45","author":"P Gugny","year":"1974","unstructured":"Gugny P: Orthodontic participation in the treatment of a case of Apert syndrome. Orthod Fr. 1974, 45: 565-573.","journal-title":"Orthod Fr"},{"key":"72_CR23","first-page":"247","volume":"70","author":"RD Rynearson","year":"2000","unstructured":"Rynearson RD: Case report: orthodontic and dentofacial orthopedic considerations in Apert's syndrome. Angle Orthod. 2000, 70: 247-252.","journal-title":"Angle Orthod"},{"key":"72_CR24","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1097\/00001665-200203000-00015","volume":"13","author":"K Matsumoto","year":"2002","unstructured":"Matsumoto K, Nakanishi H, Koizumi Y, Seike T, Okazaki M, Yokozeki M, Moriyama K: Segmental distraction of the midface in a patient with Crouzon syndrome. J Craniofac Surg. 2002, 13: 273-278. 10.1097\/00001665-200203000-00015.","journal-title":"J Craniofac Surg"},{"issue":"Pt 2","key":"72_CR25","first-page":"635","volume":"59","author":"P Gugny","year":"1988","unstructured":"Gugny P, ViFane B: Current aspects of orthodontic treatment of craniofacial stenoses. Orthod Fr. 1988, 59 (Pt 2): 635-645.","journal-title":"Orthod Fr"},{"key":"72_CR26","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1046\/j.1365-2214.2001.00224.x","volume":"27","author":"K Sarimski","year":"2001","unstructured":"Sarimski K: Social adjustment of children with a severe craniofacial anomaly (Apert syndrome). Child Care Health Dev. 2001, 27: 583-590. 10.1046\/j.1365-2214.2001.00224.x.","journal-title":"Child Care Health Dev"},{"key":"72_CR27","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/s100060100309","volume":"5","author":"D Weingart","year":"2001","unstructured":"Weingart D, Roser M, Lantos P: Mid-face distraction after LeFort III osteotomy in craniofacial dysmorphism. Mund Kiefer Gesichtschir. 2001, 5: 221-226.","journal-title":"Mund Kiefer Gesichtschir"},{"key":"72_CR28","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1097\/01.PRS.0000160271.08827.15","volume":"115","author":"JA Fearon","year":"2005","unstructured":"Fearon JA: Halo distraction of the LeFort III in syndromic craniosynostosis: a long-term assessment. Plast Reconstr Surg. 2005, 115: 1524-1536. 10.1097\/01.PRS.0000160271.08827.15.","journal-title":"Plast Reconstr Surg"},{"key":"72_CR29","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1097\/00001665-200411000-00020","volume":"15","author":"TR Meling","year":"2004","unstructured":"Meling TR, Due-Tonnessen BJ, Hogevold HE, Skjelbred P, Arctander K: Monobloc distraction osteogenesis in pediatric patients with severe syndromal craniosynostosis. J Craniofac Surg. 2004, 15: 990-1001. 10.1097\/00001665-200411000-00020.","journal-title":"J Craniofac Surg"},{"key":"72_CR30","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/01.prs.0000194903.45939.b8","volume":"117","author":"H Yano","year":"2006","unstructured":"Yano H, Tanaka K, Sueyoshi O, Takahashi K, Hirata R, Hirano A: Cranial vault distraction: its illusionary effect and limitation. Plast Reconstr Surg. 2006, 117: 193-201. 10.1097\/01.prs.0000194903.45939.b8.","journal-title":"Plast Reconstr Surg"},{"key":"72_CR31","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1097\/01.PRS.0000047440.06788.72","volume":"111","author":"K Satoh","year":"2003","unstructured":"Satoh K, Mitsukawa N, Hosaka Y: Dual midfacial distraction osteogenesis: LeFort III minus I and LeFort I for syndromic craniosynostosis. Plast Reconstr Surg. 2003, 111: 1019-1028. 10.1097\/01.PRS.0000047440.06788.72.","journal-title":"Plast Reconstr Surg"},{"key":"72_CR32","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1007\/s00056-0510-8","volume":"66","author":"C Lippold","year":"2005","unstructured":"Lippold C, Danesh G, Meyer U, Hohoff A, Kelker M, Kleinheinz J: Potential and limitations of cephalometric analysis of maxillofacial bone movement in the case of LeFort III-distraction. J Orofac Orthop. 2005, 66: 388-396. 10.1007\/s00056-0510-8.","journal-title":"J Orofac Orthop"},{"key":"72_CR33","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1378\/chest.88.5.776","volume":"88","author":"C Guilleminault","year":"1985","unstructured":"Guilleminault C, Riley R, Powell N: Sleep apnea in normal subjects following mandibular osteotomy with retrusion. Chest. 1985, 88: 776-778.","journal-title":"Chest"},{"key":"72_CR34","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/0278-2391(87)90016-4","volume":"45","author":"RW Riley","year":"1987","unstructured":"Riley RW, Powell NB, Guilleminault C, Ware W: Obstructive sleep apnea syndrome following surgery for mandibular prognathism. J Oral Maxillofac Surg. 1987, 45: 450-452.","journal-title":"J Oral Maxillofac Surg"},{"key":"72_CR35","first-page":"91","volume-title":"Advances and technical standards in neurosurgery","author":"H Powiertowski","year":"1974","unstructured":"Powiertowski H: Surgery of craniosynostosos in avanced cases. Advances and technical standards in neurosurgery. Edited by: Krayenb\u00fchl H. 1974, Wien, New York: Springer, 91-"}],"container-title":["Head &amp; Face Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1746-160X-3-10\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-3-10.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-3-10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-3-10.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T21:38:46Z","timestamp":1707601126000},"score":1,"resource":{"primary":{"URL":"https:\/\/head-face-med.biomedcentral.com\/articles\/10.1186\/1746-160X-3-10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,8]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["72"],"URL":"https:\/\/doi.org\/10.1186\/1746-160x-3-10","relation":{},"ISSN":["1746-160X"],"issn-type":[{"value":"1746-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,8]]},"article-number":"10"}}