{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T06:47:06Z","timestamp":1772347626381,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,1,26]],"date-time":"2011-01-26T00:00:00Z","timestamp":1296000000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head Face Med"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The influence of surgery on growth and stability after treatment in patients with cleft lip and palate are topics still under discussion. The aim of the present study was to investigate the influence of early lip closure on the width of the alveolar cleft using dental casts.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A total of 44 clefts were investigated using plaster casts, 30 unilateral and 7 bilateral clefts. All infants received a passive molding plate a few days after birth. The age at the time of closure of the lip was 2.1 month in average (range 1-6 months). Plaster casts were obtained at the following stages: shortly after birth, prior to lip closure, prior to soft palate closure. We determined the width of the alveolar cleft before lip closure and prior to soft palate closure measuring the alveolar cleft width from the most lateral point of the premaxilla\/anterior segment to the most medial point of the smaller segment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>After lip closure 15 clefts presented with a width of 0 mm, meaning that the mucosa of the segments was almost touching one another. 19 clefts showed a width of up to 2 mm and 10 clefts were still over 2 mm wide. This means a reduction of 0% in 5 clefts, of 1-50% in 6 clefts, of 51-99% in 19 clefts, and of 100% in 14 clefts.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Early lip closure reduces alveolar cleft width. In most cases our aim of a remaining cleft width of 2 mm or less can be achieved. These are promising conditions for primary alveolar bone grafting to restore the dental bony arch.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1746-160x-7-3","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T07:15:45Z","timestamp":1296112545000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Influence of lip closure on alveolar cleft width in patients with cleft lip and palate"],"prefix":"10.1186","volume":"7","author":[{"given":"Wolfgang","family":"Eichhorn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Blessmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Vorwig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerd","family":"Gehrke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Schmelzle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Heiland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,1,26]]},"reference":[{"key":"195_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1097\/00006534-197701000-00016","volume":"59","author":"N Robertson","year":"1977","unstructured":"Robertson N, Shaw W, Volp C: The changes produced by presurgical orthopedic treatment of bilateral cleft lip and palate. Plast Reconstr Surg. 1977, 59: 86-93. 10.1097\/00006534-197701000-00016.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR2","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1597\/1545-1569(1990)027<0076:TIOCLR>2.3.CO;2","volume":"27","author":"J Bardach","year":"1990","unstructured":"Bardach J: The influence of cleft lip repair on facial growth. Cleft Palate J. 1990, 27: 76-78. 10.1597\/1545-1569(1990)027<0076:TIOCLR>2.3.CO;2.","journal-title":"Cleft Palate J"},{"key":"195_CR3","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1597\/1545-1569(1997)034<0021:MAMDAD>2.3.CO;2","volume":"34","author":"KLWM Heidbuchel","year":"1997","unstructured":"Heidbuchel KLWM, Kuijpers-Jagtman AM: Maxillary and mandibular dental-arch dimensions and occlusion in bilateral cleft lip and palate patients from 3 to 17 years of age. Cleft Palate-Craniofac J. 1997, 34: 21-26. 10.1597\/1545-1569(1997)034<0021:MAMDAD>2.3.CO;2.","journal-title":"Cleft Palate-Craniofac J"},{"key":"195_CR4","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/S1010-5182(98)80003-6","volume":"26","author":"KLWM Heidbuchel","year":"1998","unstructured":"Heidbuchel KLWM, Kuijpers-Jagtman AM, Van'tHof MA, Kramer GJC, Prahl-Andersen B: Effects of early treatment on maxillary arch development in BCLP. A study on dental casts between 0 and 4 years of age. J Cranio-Maxillofac Surg. 1998, 26: 140-147. 10.1016\/S1010-5182(98)80003-6.","journal-title":"J Cranio-Maxillofac Surg"},{"key":"195_CR5","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1053\/joms.2001.25852","volume":"59","author":"GE Anastassov","year":"2001","unstructured":"Anastassov GE, Joos U: Comprehensive management of cleft lip and palate deformities. J Oral Maxillofac J. 2001, 59: 1062-1075. 10.1053\/joms.2001.25852.","journal-title":"J Oral Maxillofac J"},{"key":"195_CR6","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1097\/01.prs.0000209467.98050.20","volume":"15","author":"BC Cho","year":"2006","unstructured":"Cho BC: Unilateral complete cleft lip and palate repair using lip adhesion combined with a passive intraoral molding appliance: surgical results and the effect on the maxillary alveolar arch. Plast Reconstr Surg. 2006, 15: 1510-1529. 10.1097\/01.prs.0000209467.98050.20.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR7","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.jcms.2006.07.858","volume":"34","author":"U Joos","year":"2006","unstructured":"Joos U, Wermker K, Kruse-Loessler B, Kleinheinz J: Influence of treatment concept, velopharyngoplasty, gender and age on hypernasality in patients with cleft lip, alveolus and palate. J Cranio-Maxillofac Surg. 2006, 34: 472-477. 10.1016\/j.jcms.2006.07.858.","journal-title":"J Cranio-Maxillofac Surg"},{"key":"195_CR8","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1597\/07-053","volume":"45","author":"T Al-Gunaid","year":"2008","unstructured":"Al-Gunaid T, Asahito T, Yamaki M, Hanada K, Takagi R, Ono K, Saito I: Relapse tendency in maxillary arch width in unilateral cleft lip and palate patients with different maxillary arch forms. Cleft Palate-Craniofac J. 2008, 45: 278-283. 10.1597\/07-053.","journal-title":"Cleft Palate-Craniofac J"},{"key":"195_CR9","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.anplas.2008.05.003","volume":"54","author":"R Le Pendeven","year":"2009","unstructured":"Le Pendeven R, Mayrtinot-Duquennoy V, Pellerin P: Long-term morphologic results of a 32 successive patients series presenting unilateral complete cleft lip and palate with surgery at early age. Ann Chir Plast Esthet. 2009, 54: 7-15. 10.1016\/j.anplas.2008.05.003.","journal-title":"Ann Chir Plast Esthet"},{"key":"195_CR10","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/PRS.0b013e31819a3502","volume":"123","author":"RA Ruotolo","year":"2009","unstructured":"Ruotolo RA, Fearon JA: Cleft lip repair: a unique sutureless skin closure rechnique. Plast Reconstr Surg. 2009, 123: 109-111. 10.1097\/PRS.0b013e31819a3502.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR11","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/0002-9416(64)90040-5","volume":"50","author":"JH Sillmann","year":"1964","unstructured":"Sillmann JH: Dimensional changes of the dental arches: Longitudinal study from birth to 25 years. Am J Orthodont. 1964, 50: 824-842. 10.1016\/0002-9416(64)90040-5.","journal-title":"Am J Orthodont"},{"key":"195_CR12","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/00006534-197507000-00011","volume":"56","author":"NG Georgiade","year":"1975","unstructured":"Georgiade NG, Latham RA: Maxillary arch alignment in the bilateral cleft lip and palate infant using the pinned coaxial screw appliance. Plast Reconstr. Surg. 1975, 56: 52-60. 10.1097\/00006534-197507000-00011.","journal-title":"Plast Reconstr. Surg"},{"key":"195_CR13","first-page":"253","volume":"13","author":"RA Latham","year":"1976","unstructured":"Latham RA, Kusy RP, Georgiade NG: An intraorally activated expansion appliance for cleft palate infants. Cleft palate J. 1976, 13: 253-261.","journal-title":"Cleft palate J"},{"key":"195_CR14","first-page":"227","volume":"17","author":"RA Latham","year":"1980","unstructured":"Latham RA: Orthopedic advancement of the cleft maxillary segment: A preliminary report. Cleft Palate J. 1980, 17: 227-233.","journal-title":"Cleft Palate J"},{"key":"195_CR15","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/0002-9416(76)90274-8","volume":"70","author":"M Hotz","year":"1976","unstructured":"Hotz M, Gnoinsky W: Comprehensive care of cleft lip and palate children at Zurich University: a preliminary report. Am J Orthod Dentofac Orthop. 1976, 70: 481-504.","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"195_CR16","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3109\/02844318709083579","volume":"21","author":"M Hotz","year":"1987","unstructured":"Hotz M, Perko M, Gnoinski W: Early orthopaedic stabilization of the praemaxilla in complete bilateral cleft lip and palate in combination with the celesnik repair. Scand J Reconstr Surg. 1987, 21: 45-51. 10.3109\/02844318709083579.","journal-title":"Scand J Reconstr Surg"},{"key":"195_CR17","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1597\/02-141.1","volume":"41","author":"S Suri","year":"2004","unstructured":"Suri S, Tompson BD: A modified muscle-activated maxillary orthopedic appliance for presurgical nasoalvelolar molding in infants with unilateral cleft lip and palate. Cleft Palate-Craniofacial J. 2004, 41: 225-229. 10.1597\/02-141.1.","journal-title":"Cleft Palate-Craniofacial J"},{"key":"195_CR18","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/0002-9416(69)90034-7","volume":"55","author":"ML Moss","year":"1969","unstructured":"Moss ML, Salentijn L: The primary role of functional matrices in facial growth. Am J Orthodont. 1969, 55: 566-577. 10.1016\/0002-9416(69)90034-7.","journal-title":"Am J Orthodont"},{"key":"195_CR19","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1597\/1545-1569(2001)038<0193:PNOMIP>2.0.CO;2","volume":"38","author":"BH Grayson","year":"2001","unstructured":"Grayson BH, Cutting CB: Presurgical nasoalveolar orthopedic molding in primary correction of the nose, lip, and alveolus of infants born with unilateral and bilateral clefts. Cleft Palate-Craniofac J. 2001, 38: 193-198. 10.1597\/1545-1569(2001)038<0193:PNOMIP>2.0.CO;2.","journal-title":"Cleft Palate-Craniofac J"},{"key":"195_CR20","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1097\/01.PRS.0000133027.04252.7A","volume":"114","author":"EJ Liou","year":"2004","unstructured":"Liou EJ, Subramanian M, Chen PKT, Huang CS: The progressive changes of nasal symmetry and growth after nasoalveolar molding: a three-year follow up study. Plast Reconstr Surg. 2004, 114: 858-864. 10.1097\/01.PRS.0000133027.04252.7A.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR21","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1097\/00006534-199905000-00009","volume":"103","author":"DR Millard","year":"1999","unstructured":"Millard DR, Latham R, Huifen X, Spiro S, Morovic C: Cleft lip and palate treated by presurgical orthopedics, gingivoperiosteoplasty, and lip adhesion (popla) compared with previous lip adhesion method: a preliminary study of serial dental casts. Plast Reconstr Surg. 1999, 103: 1630-1644. 10.1097\/00006534-199905060-00009.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR22","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.jcms.2009.07.009","volume":"37","author":"W Eichhorn","year":"2009","unstructured":"Eichhorn W, Blessmann M, Pohlenz P, Blake FAS, Gehrke G, Schmelzle R, Heiland M: Primary osteoplasty using calvarian bone in patients with cleft lip, alveolus and palate. J Cranio-Maxillofac Surg. 2009, 37: 429-433. 10.1016\/j.jcms.2009.07.009.","journal-title":"J Cranio-Maxillofac Surg"},{"key":"195_CR23","first-page":"93","volume":"78","author":"J Delaire","year":"1977","unstructured":"Delaire J, F\u00e8ve JR, Chateau JP, Courtay D, Tulasne JF: Anatomie et physiologie des muscles et du frein median de la l\u00e8vre sup\u00e9riuere: Premiers resultats de l'\u00e9lectromygraphie selective. Rev Stomatol. 1977, 78: 93-103.","journal-title":"Rev Stomatol"},{"key":"195_CR24","first-page":"125","volume":"32","author":"U Joos","year":"1987","unstructured":"Joos U, Friedburg H: Darstellung und Verlauf der mimischen Muskulatur in der Kernspintomographie. Fortschr Kiefer Gesichtschir. 1987, 32: 125-127.","journal-title":"Fortschr Kiefer Gesichtschir"},{"key":"195_CR25","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0266-4356(95)90285-6","volume":"33","author":"U Joos","year":"1995","unstructured":"Joos U: Skeletal growth after muscular reconstruction for cleft lip, alveolus, and palate. Br J Oral Maxillofac Surg. 1995, 33: 139-144. 10.1016\/0266-4356(95)90285-6.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"195_CR26","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/S1010-5182(89)80029-0","volume":"17","author":"U Joos","year":"1989","unstructured":"Joos U: Muscle reconstruction in primary cleft lip surgery. J Cranio-Maxfac Surg. 1989, 17: 8-10. 10.1016\/S1010-5182(89)80029-0.","journal-title":"J Cranio-Maxfac Surg"},{"key":"195_CR27","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3109\/02844318709083588","volume":"21","author":"U Joos","year":"1987","unstructured":"Joos U: The importance of muscular reconstruction in the treatment of cleft lip and palate. Scand J Plast Reconstr Surg. 1987, 21: 109-113. 10.3109\/02844318709083588.","journal-title":"Scand J Plast Reconstr Surg"},{"key":"195_CR28","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1597\/1545-1569(1994)031<0376:PCALSI>2.3.CO;2","volume":"31","author":"GJC Kramer","year":"1994","unstructured":"Kramer GJC, Hoeksma JB, Prahl-Andersen B: Palatal changes after lip surgery in different types of cleft lip and palate. Cleft Palate-Craniofac J. 1994, 31: 376-384. 10.1597\/1545-1569(1994)031<0376:PCALSI>2.3.CO;2.","journal-title":"Cleft Palate-Craniofac J"},{"key":"195_CR29","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1746-160X-6-18","volume":"6","author":"CL Heike","year":"2010","unstructured":"Heike CL, Upson K, Stuhaug E, Weinberg SM: A practical guide to facial image acquisition. Head and Face Medicine. 2010, 6: 6-18. 10.1186\/1746-160X-6-6.","journal-title":"Head and Face Medicine"},{"key":"195_CR30","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1097\/00006534-199909010-00001","volume":"104","author":"EJ Stelnicki","year":"1999","unstructured":"Stelnicki EJ, Lee S, Hoffmann W, Lopoo J, Foster R, Harrison M, Longaker M: A long-term, controlled-outcome analysis of in utero versus neonatal cleft lip repair using an ovine model. Plast Reconstr Surg. 1999, 104: 607-615. 10.1097\/00006534-199909030-00001.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00006534-199807000-00001","volume":"102","author":"K Oberg","year":"1998","unstructured":"Oberg K, Robles A, Ducsay C, Childers B, Rasi C, Gates D, Kirsch WM, Hardesty R: Endoscopic excision and repair of simulated bilateral cleft lips in fetal lambs. Plast Reconstr Surg. 1998, 102: 1-9. 10.1097\/00006534-199807000-00001.","journal-title":"Plast Reconstr Surg"},{"key":"195_CR32","doi-asserted-by":"publisher","first-page":"2479","DOI":"10.1016\/j.joms.2007.06.642","volume":"65","author":"MHO Wenghoefer","year":"2007","unstructured":"Wenghoefer MHO, Deprest J, Goetz W, Kuijpers-Jagtman AM, Berg\u00e9 S: Prenatal cleft lip and maxillary alveolar defect repair in a 2-step fetal lamb model. J Oral Maxillofac Surg. 2007, 65: 2479-2486. 10.1016\/j.joms.2007.06.642.","journal-title":"J Oral Maxillofac Surg"}],"container-title":["Head &amp; Face Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-7-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1746-160X-7-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-7-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1746-160X-7-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T06:27:25Z","timestamp":1630477645000},"score":1,"resource":{"primary":{"URL":"https:\/\/head-face-med.biomedcentral.com\/articles\/10.1186\/1746-160X-7-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,26]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["195"],"URL":"https:\/\/doi.org\/10.1186\/1746-160x-7-3","relation":{},"ISSN":["1746-160X"],"issn-type":[{"value":"1746-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,26]]},"assertion":[{"value":"18 October 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"3"}}