{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:53:27Z","timestamp":1761155607341},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T00:00:00Z","timestamp":1345593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiat Oncol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1748-717x-7-141","type":"journal-article","created":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T10:15:04Z","timestamp":1345630504000},"source":"Crossref","is-referenced-by-count":15,"title":["Higher toxicity with 42 Gy in 10 fractions as a total dose for 3D-conformal accelerated partial breast irradiation: results from a dose escalation phase II trial"],"prefix":"10.1186","volume":"7","author":[{"given":"Celine","family":"Bourgier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Acevedo-Henao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariane","family":"Dunant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Rossier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonin","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"El Nemr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Dumas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzette","family":"Delaloge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Christine","family":"Mathieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Remi","family":"Garbay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alphonse","family":"Taghian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Marsiglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,8,22]]},"reference":[{"key":"665_CR1","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1056\/NEJMoa0906260","volume":"362","author":"TJ Whelan","year":"2010","unstructured":"Whelan TJ, Pignol JP, Levine MN, et al.: Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med 2010, 362: 513-520. 10.1056\/NEJMoa0906260","journal-title":"N Engl J Med"},{"key":"665_CR2","volume-title":"A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer","author":"F Vicini","year":"2007","unstructured":"Vicini F: A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer. NSABP PROTOCOL B-39 - RTOG PROTOCOL 0413, Pittsburgh, PA; 2007."},{"key":"665_CR3","volume-title":"A Multi-centre Randomized Trial to Determine if Accelerated Partial Breast Irradiation, Utilizing 3D CRT, is as Effective as Whole Breast Irradiation Following Breast Conserving Surgery in Women With Ductal Carcinoma in Situ or Invasive Breast Cancer With","author":"TJ Whelan","year":"2006","unstructured":"Whelan TJ: A Multi-centre Randomized Trial to Determine if Accelerated Partial Breast Irradiation, Utilizing 3D CRT, is as Effective as Whole Breast Irradiation Following Breast Conserving Surgery in Women With Ductal Carcinoma in Situ or Invasive Breast Cancer With Negative Axillary Lymph Nodes. NCT00282035 - OCOG-2005-RAPID, Ontario; 2006."},{"key":"665_CR4","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/j.ijrobp.2009.02.031","volume":"74","author":"BD Smith","year":"2009","unstructured":"Smith BD, Arthur DW, Buchholz TA, et al.: Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO). Int J Radiat Oncol Biol Phys 2009, 74: 987-1001. 10.1016\/j.ijrobp.2009.02.031","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR5","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.radonc.2010.01.014","volume":"94","author":"C Polgar","year":"2010","unstructured":"Polgar C, Van Limbergen E, Potter R, et al.: Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: recommendations of the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009). Radiother Oncol 2010, 94: 264-273. 10.1016\/j.radonc.2010.01.014","journal-title":"Radiother Oncol"},{"key":"665_CR6","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.brachy.2009.02.002","volume":"8","author":"AG Taghian","year":"2009","unstructured":"Taghian AG, Bourgier C: Counterpoint: conformal external beam for accelerated partial breast irradiation. Brachytherapy 2009, 8: 184-188. discussion 190 10.1016\/j.brachy.2009.02.002","journal-title":"Brachytherapy"},{"key":"665_CR7","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1016\/j.ijrobp.2010.07.040","volume":"81","author":"C Bourgier","year":"2010","unstructured":"Bourgier C, Pichenot C, Verstraet R, et al.: Early side effects of three-dimensional conformal external beam accelerated partial breast irradiation to a total dose of 40 Gy in one week (a phase II trial). Int J Radiat Oncol Biol Phys 2010, 81: 1228-1235.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl 1","key":"665_CR8","doi-asserted-by":"publisher","first-page":"S127","DOI":"10.1016\/S1278-3218(10)70016-0","volume":"14","author":"I Ghorbel","year":"2010","unstructured":"Ghorbel I, Kanoun S, Kallel A, et al.: Early breast cancer without axillary lymph node involvement. Cancer Radiother 2010,14(Suppl 1):S127-S135.","journal-title":"Cancer Radiother"},{"key":"665_CR9","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1748-717X-4-70","volume":"4","author":"M Dzhugashvili","year":"2009","unstructured":"Dzhugashvili M, Tournay E, Pichenot C, et al.: 3D-conformal accelerated partial breast irradiation treatment planning: the value of surgical clips in the delineation of the lumpectomy cavity. Radiat Oncol 2009, 4: 70. 10.1186\/1748-717X-4-70","journal-title":"Radiat Oncol"},{"key":"665_CR10","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1016\/j.ijrobp.2009.04.089","volume":"76","author":"M Dzhugashvili","year":"2010","unstructured":"Dzhugashvili M, Pichenot C, Dunant A, et al.: Surgical clips assist in the visualization of the lumpectomy cavity in three-dimensional conformal accelerated partial-breast irradiation. Int J Radiat Oncol Biol Phys 2010, 76: 1320-1324. 10.1016\/j.ijrobp.2009.04.089","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR11","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1016\/j.canrad.2010.05.006","volume":"14","author":"C Bourgier","year":"2010","unstructured":"Bourgier C, Pichenot C, Verstraet R, et al.: \u00c9tude pilote fran\u00e7aise de phase II d'irradiation partielle acc\u00e9l\u00e9r\u00e9e du sein conformationnelle tridimensionnelle bi-fractionn\u00e9e hebdomadaire de 40 Gy. Cancer\/Radioth\u00e9rapie 2010, 14: 718-726.","journal-title":"Cancer\/Radioth\u00e9rapie"},{"key":"665_CR12","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/j.ijrobp.2009.06.067","volume":"77","author":"F Vicini","year":"2009","unstructured":"Vicini F, Winter K, Wong J, et al.: Initial efficacy results of RTOG 0319: three-dimensional conformal radiation therapy (3D-CRT) confined to the region of the lumpectomy cavity for stage I\/II breast carcinoma. Int J Radiat Oncol Biol Phys 2009, 77: 1120-1127.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR13","doi-asserted-by":"publisher","first-page":"3887","DOI":"10.1200\/JCO.2008.20.0121","volume":"27","author":"A Recht","year":"2009","unstructured":"Recht A, Ancukiewicz M, Alm El-Din MA, et al.: Lung dose-volume parameters and the risk of pneumonitis for patients treated with accelerated partial-breast irradiation using three-dimensional conformal radiotherapy. J Clin Oncol 2009, 27: 3887-3893. 10.1200\/JCO.2008.20.0121","journal-title":"J Clin Oncol"},{"key":"665_CR14","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.ijrobp.2009.04.070","volume":"77","author":"L Livi","year":"2010","unstructured":"Livi L, Buonamici FB, Simontacchi G, et al.: Accelerated partial breast irradiation with IMRT: new technical approach and interim analysis of acute toxicity in a phase III randomized clinical trial. Int J Radiat Oncol Biol Phys 2010, 77: 509-515. 10.1016\/j.ijrobp.2009.04.070","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR15","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1016\/j.ijrobp.2011.02.024","volume":"82","author":"AA Lewin","year":"2011","unstructured":"Lewin AA, Derhagopian R, Saigal K, et al.: Accelerated partial breast irradiation is safe and effective using intensity-modulated radiation therapy in selected early-stage breast cancer. Int J Radiat Oncol Biol Phys 2011, 82: 2104-2110.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR16","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/j.ijrobp.2009.06.067","volume":"77","author":"F Vicini","year":"2010","unstructured":"Vicini F, Winter K, Wong J, et al.: Initial efficacy results of RTOG 0319: three-dimensional conformal radiation therapy (3D-CRT) confined to the region of the lumpectomy cavity for stage I\/II breast carcinoma. Int J Radiat Oncol Biol Phys 2010, 77: 1120-1127. 10.1016\/j.ijrobp.2009.06.067","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR17","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1016\/j.ijrobp.2009.01.009","volume":"75","author":"JT Hepel","year":"2009","unstructured":"Hepel JT, Tokita M, MacAusland SG, et al.: Toxicity of three-dimensional conformal radiotherapy for accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 2009, 75: 1290-1296. 10.1016\/j.ijrobp.2009.01.009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR18","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1016\/j.ijrobp.2010.06.062","volume":"81","author":"SF Shaitelman","year":"2010","unstructured":"Shaitelman SF, Kim LH, Grills IS, et al.: Predictors of long-term toxicity using three-dimensional conformal external beam radiotherapy to deliver accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 2010, 81: 788-794.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"665_CR19","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1016\/j.ijrobp.2005.09.042","volume":"64","author":"AG Taghian","year":"2006","unstructured":"Taghian AG, Kozak KR, Doppke KP, et al.: Initial dosimetric experience using simple three-dimensional conformal external-beam accelerated partial-breast irradiation. Int J Radiat Oncol Biol Phys 2006, 64: 1092-1099. 10.1016\/j.ijrobp.2005.09.042","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1748-717X-7-141.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1748-717X-7-141\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1748-717X-7-141.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T05:15:25Z","timestamp":1548220525000},"score":1,"resource":{"primary":{"URL":"https:\/\/ro-journal.biomedcentral.com\/articles\/10.1186\/1748-717X-7-141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,22]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["665"],"URL":"https:\/\/doi.org\/10.1186\/1748-717x-7-141","relation":{},"ISSN":["1748-717X"],"issn-type":[{"value":"1748-717X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,22]]},"article-number":"141"}}