{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:54:06Z","timestamp":1761155646161},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiat Oncol"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>To evaluate the efficacy of radiotherapy (RT) for early-stage nodal and extranodal marginal zone lymphoma (MZL).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Materials and methods<\/jats:title>\n            <jats:p>Patients with stage I (n\u2009=\u200922) and stage II (n\u2009=\u20098) MZL, who were treated with RT were reviewed. The primary tumor localisation was in the orbita (n\u2009=\u200912), stomach (n\u2009=\u20098), head and neck other than the orbita (n\u2009=\u20098), breast (n\u2009=\u20091) and one case of marginal zone lymphoma of the skin (n\u2009=\u20091). The median radiotherapy dose was 40 Gy (5 to 45 Gy).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The median follow-up time was 103 months. The 5-year overall survival and event-free survival rates were 85\u2009\u00b1\u20097% and 71\u2009\u00b1\u20099%, respectively. There was no infield recurrence. Recurrence occurred outside of the radiation field in six patients. The relapses were treated with salvage RT and had excellent local control (100%) at five years after salvage RT.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Localized extranodal MZL have an excellent prognosis following moderate-dose RT. RT is also an effective salvage therapy in cases of localized recurrence. Further clinical studies should evaluate the optimal dose for MZL.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1748-717x-8-2","type":"journal-article","created":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T13:25:16Z","timestamp":1357133116000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Radiotherapy in marginal zone lymphoma"],"prefix":"10.1186","volume":"8","author":[{"given":"Kristin","family":"Deinbeck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Geinitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Haller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khashayar","family":"Fakhrian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,1,2]]},"reference":[{"key":"737_CR1","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1002\/1097-0142(19831015)52:8<1410::AID-CNCR2820520813>3.0.CO;2-3","volume":"52","author":"P Isaacson","year":"1983","unstructured":"Isaacson P, Wright DH: Malignant lymphoma of mucosa-associated lymphoid tissue: A distinctive type of B-cell lymphoma. 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