{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T16:58:12Z","timestamp":1763398692079},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T00:00:00Z","timestamp":1322006400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objectives<\/jats:title>\n            <jats:p>Preventing stroke after coronary artery bypass grafting (CABG) remains a therapeutic goal, due in part to the lack of identifiable risk factors. The aim of this study, accordingly, was to identify risk factors in CABG patients with a previous history of stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients with a history of stroke who underwent CABG at Beijing An Zhen hospital from January 2007 to July 2010 were selected (n = 430), and divided into two groups according to the occurrence of postoperative stroke. Pre-operative and post-operative data were retrospectively collected and analyzed by univariate and multivariate logistic regression analyses.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Thirty-two patients (7.4%) suffered post-operative stroke. Univariate analysis identified several statistically significant risk factors in the post-operative stroke group, including pre-surgical left ventricular ejection fractions (LVEF) \u226450%, on-pump surgery, post-operative atrial fibrillation (AF), and hypotension. Multivariable analysis identified 4 independent risk factors for recurrent stroke: unstable angina (odds ratio (OR) = 2.95, 95% CI: 1.05-8.28), LVEF \u226450% (OR = 2.77, 95% CI: 1.23-6.27), AF (OR = 4.69, 95% CI: 1.89-11.63), and hypotension (OR = 2.55, 95% CI: 1.07-6.04).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Unstable angina, LVEF \u226450%, post-operative AF, and post-operative hypotension are independent risk factors of recurrent stroke in CABG patients with a previous history of stroke.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1749-8090-6-157","type":"journal-article","created":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T19:34:36Z","timestamp":1322076876000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Risk Factors For Recurrent Stroke After Coronary Artery Bypass Grafting"],"prefix":"10.1186","volume":"6","author":[{"given":"Li","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-Jun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,11,23]]},"reference":[{"key":"520_CR1","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/0003-4975(95)00903-5","volume":"61","author":"JM Redmond","year":"1996","unstructured":"Redmond JM, Greene PS, Goldsborough MA, Cameron DE, Stuart RS, Sussman MS, Watkins L, Laschinger JC, McKhann GM, Johnston MV, Baumgartner WA: Neurologic injury in cardiac surgical patients with a history of stroke. Ann Thorac Surg. 1996, 61: 42-7. 10.1016\/0003-4975(95)00903-5.","journal-title":"Ann Thorac Surg"},{"key":"520_CR2","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1161\/01.STR.32.7.1508","volume":"32","author":"SC Stamou","year":"2001","unstructured":"Stamou SC, Hill PC, Dangas G, Pfister AJ, Boyce SW, Dullum MK, Bafi AS, Corso PJ: Stroke after coronary artery bypass:incidence, predictors, and clinical outcome editorial comment: incidence, predictors, and clinical outcome. Stroke. 2001, 32: 1508-13. 10.1161\/01.STR.32.7.1508.","journal-title":"Stroke"},{"key":"520_CR3","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/S0003-4975(02)04370-9","volume":"75","author":"J Bucerius","year":"2003","unstructured":"Bucerius J, Gummert JF, Borger MA, Walther T, Doll N, Onnasch JF, Metz S, Falk V, Mohr FW: Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients. Ann Thorac Surg. 2003, 75: 472-478. 10.1016\/S0003-4975(02)04370-9.","journal-title":"Ann Thorac Surg"},{"key":"520_CR4","first-page":"63","volume":"50","author":"L Noyez","year":"2009","unstructured":"Noyez L, Van Swieten HA: Stroke after coronary artery bypass grafting. Is there place for a stroke-risk stratification model?. The Journal of Cardiovascular Surgery. 2009, 50: 63-69.","journal-title":"The Journal of Cardiovascular Surgery"},{"key":"520_CR5","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/S0741-5214(95)70253-9","volume":"21","author":"LB Schwartz","year":"1995","unstructured":"Schwartz LB, Bridgman AH, Kieffer RW, Wilcox RA, McCann RL, Tawil MP, Scott SM: Asymptomatic carotid artery stenosis and stroke in patients undergoing cardiovascular bypass. J Vasc Surg. 1995, 21: 146-53. 10.1016\/S0741-5214(95)70253-9.","journal-title":"J Vasc Surg"},{"key":"520_CR6","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S0167-5273(00)00251-5","volume":"74","author":"SK Das","year":"2000","unstructured":"Das SK, Brow TD, Pepper J: Continuing controversy in the management of concomitant coronary and carotid disease: an overview. International Journal of Cardiology. 2000, 74: 47-65. 10.1016\/S0167-5273(00)00251-5.","journal-title":"International Journal of Cardiology"},{"key":"520_CR7","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/S0741-5214(95)70254-7","volume":"21","author":"GC Salasidis","year":"1995","unstructured":"Salasidis GC, Latter DA, Steinmetz OK, Blair JF, Graham AM: Carotid artery duplex scanning in preoperative assessment for coronary artery revascularization. J Vasc Surg. 1995, 21: 154-61. 10.1016\/S0741-5214(95)70254-7.","journal-title":"J Vasc Surg"},{"key":"520_CR8","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1016\/S0003-4975(96)00885-5","volume":"62","author":"RS D'Agostino","year":"1996","unstructured":"D'Agostino RS, Svensson LG, Neumann DJ, Balkhy HH, Williamson WA, Shahian DM: Screening carotid ultrasonography and risk factors for stroke in coronary artery surgery patients. Ann Thorac Surg. 1996, 62: 1714-23. 10.1016\/S0003-4975(96)00885-5.","journal-title":"Ann Thorac Surg"},{"key":"520_CR9","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.jtcvs.2007.03.018","volume":"134","author":"J Schoof","year":"2007","unstructured":"Schoof J, Lubahn W, Baeumer M, Kross R, Wallesch CW, Kozian A, Huth C, Goertler M: Impaired cerebral autoregulation distal to carotid stenosis\/occlusion is associated with increased risk of stroke at cardiac surgery with cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2007, 134: 690-6. 10.1016\/j.jtcvs.2007.03.018.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"520_CR10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1136\/jnnp.57.1.17","volume":"57","author":"J Ogata","year":"1994","unstructured":"Ogata J, Masuda J, Yutani C, Yamaguchi T: Mechanisms of cerebral artery thrombosis: a histopathological analysis on eight necropsy cases. J Neurol Neurosurg Psychiatry. 1994, 57: 17-21. 10.1136\/jnnp.57.1.17.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"520_CR11","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/j.jacc.2003.09.047","volume":"43","author":"GK Peel","year":"2004","unstructured":"Peel GK, Stamou SC, Dullum MK, Hill PC, Jablonski KA, Bafi AS, Boyce SW, Petro KR, Corso PJ: Chronologic distribution of stroke after minimally invasive versus conventional coronary artery bypass. J Am Coll Cardiol. 2004, 43: 752-756. 10.1016\/j.jacc.2003.09.047.","journal-title":"J Am Coll Cardiol"},{"key":"520_CR12","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/j.athoracsur.2007.10.060","volume":"85","author":"F Filsoufi","year":"2008","unstructured":"Filsoufi F, Rahmanian PB, Castillo JG, Bronster D, Adams DH: Incidence, topography, predictors and long-term survival after stroke in patients undergoing coronary artery bypass grafting. Ann Thorac Surg. 2008, 85: 862-870. 10.1016\/j.athoracsur.2007.10.060.","journal-title":"Ann Thorac Surg"},{"key":"520_CR13","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/S1010-7940(03)00440-8","volume":"24","author":"G Ancona","year":"2003","unstructured":"Ancona G, Saez de Ibarra JI, Baillot R: Determinants of stroke after coronary artery bypass grafting. Eur J Cardiothorac Surg. 2003, 24: 552-556. 10.1016\/S1010-7940(03)00440-8.","journal-title":"Eur J Cardiothorac Surg"},{"key":"520_CR14","first-page":"48","volume":"17","author":"M Tadic","year":"2010","unstructured":"Tadic M, Ivanovic B, Zivkovic N: Predictors of atrial fibrillation following coronary artery bypass surgery. Med Sci Monit. 2010, 17: 48-55.","journal-title":"Med Sci Monit"},{"issue":"5","key":"520_CR15","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/j.ejcts.2009.05.003","volume":"36","author":"YS Choi","year":"2009","unstructured":"Choi YS, Shim JK, Hong SW, Kim DH, Kim JC, Kwak YL: Risk factors of atrial fibrillation following off-pump coronary artery bypass graft surgery: predictive value of C-reactive protein and transfusion requirement. Eur J Cardiothorac Surg. 2009, 36 (5): 838-43. 10.1016\/j.ejcts.2009.05.003.","journal-title":"Eur J Cardiothorac Surg"},{"key":"520_CR16","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.jacc.2003.11.023","volume":"43","author":"RP Villareal","year":"2004","unstructured":"Villareal RP, Hariharan R, Liu BC, Kar B, Lee VV, Elayda M, Lopez JA, Rasekh A, Wilson JM, Massumi Al: Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. J Am Coll Cardiol. 2004, 43: 742-748. 10.1016\/j.jacc.2003.11.023.","journal-title":"J Am Coll Cardiol"},{"key":"520_CR17","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.athoracsur.2006.03.037","volume":"82","author":"A Kollar","year":"2006","unstructured":"Kollar A, Lick SD, Vasquez KN, Conti VR: Relationship of atrial fibrillation and stroke after coronary artery bypass graft surgery: when is anticoagulation indicated?. Ann Thorac Surg. 2006, 82: 515-523. 10.1016\/j.athoracsur.2006.03.037.","journal-title":"Ann Thorac Surg"},{"key":"520_CR18","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/j.athoracsur.2003.09.077","volume":"77","author":"J Lahtinen","year":"2004","unstructured":"Lahtinen J, Biancari F, Salmela E, Mosorin M, Satta J, Rainio P, Rimpil\u00e4inen J, Lepoj\u00e4rvi M, Juvonen T: Postoperative atrial fibrillation is a major cause of stroke after on-pump coronary artery bypass surgery. Ann Thorac Surg. 2004, 77: 1241-1244. 10.1016\/j.athoracsur.2003.09.077.","journal-title":"Ann Thorac Surg"},{"key":"520_CR19","first-page":"2306","volume-title":"Watershed strokes after cardiac surgery: diagnosis, etiology, and outcome, Stroke","author":"RF Gottesman","year":"2006","unstructured":"Gottesman RF, Sherman PM, Grega MA, Yousem DM, Borowicz LM, Selnes OA, Baumgartner WA, McKhann GM: Watershed strokes after cardiac surgery: diagnosis, etiology, and outcome, Stroke. 2006, 37: 2306-2311."},{"key":"520_CR20","first-page":"115","volume":"3","author":"Peiyi Gao","year":"2008","unstructured":"Gao Peiyi: CT perfusion imaging and stages of regional cerebral hypoperfusion in pre-infarction period. Chin J Stroke. 2008, 3: 115-119.","journal-title":"Chin J Stroke"},{"key":"520_CR21","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1177\/021849230601400111","volume":"14","author":"S Ohuchi","year":"2006","unstructured":"Ohuchi S, Kawazoe K, Izumoto H, Yoshioka K: Magnetic resonance angiography in coronary artery bypass grafting. Asian Cardiovasc Thorac Ann. 2006, 14: 43-6.","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"520_CR22","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.ejcts.2010.03.021","volume":"38","author":"Doi Kiyoshi","year":"2010","unstructured":"Kiyoshi Doi, Hitoshi Yaku: Importance of cerebral artery risk evaluation before off-pump coronary artery bypass grafting to avoid perioperative stroke. European Journal of Cardio-thoracic Surgery. 2010, 38: 568-572. 10.1016\/j.ejcts.2010.03.021.","journal-title":"European Journal of Cardio-thoracic Surgery"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1749-8090-6-157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1749-8090-6-157\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1749-8090-6-157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1749-8090-6-157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T18:00:44Z","timestamp":1630519244000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/1749-8090-6-157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,23]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["520"],"URL":"https:\/\/doi.org\/10.1186\/1749-8090-6-157","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,23]]},"assertion":[{"value":"22 July 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"157"}}