{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:35:45Z","timestamp":1790303745579,"version":"4.1.0"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,5,22]],"date-time":"2008-05-22T00:00:00Z","timestamp":1211414400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Syst Biol"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1186\/1752-0509-2-46","type":"journal-article","created":{"date-parts":[[2008,5,22]],"date-time":"2008-05-22T18:14:18Z","timestamp":1211480058000},"source":"Crossref","is-referenced-by-count":52,"title":["Transcription profiling of lung adenocarcinomas of c-myc-transgenic mice: Identification of the c-myc regulatory gene network"],"prefix":"10.1186","volume":"2","author":[{"given":"Susanne","family":"Reymann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Borlak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,5,22]]},"reference":[{"key":"203_CR1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/nm1087","volume":"10","author":"B Vogelstein","year":"2004","unstructured":"Vogelstein B, Kinzler KW: Cancer genes and the pathways they control. Nat Med. 2004, 10: 789-799. 10.1038\/nm1087","journal-title":"Nat Med"},{"key":"203_CR2","doi-asserted-by":"publisher","first-page":"3004","DOI":"10.1038\/sj.onc.1202746","volume":"18","author":"CE Nesbit","year":"1999","unstructured":"Nesbit CE, Tersak JM, Prochownik EV: MYC oncogenes and human neoplastic disease. Oncogene. 1999, 18: 3004-3016. 10.1038\/sj.onc.1202746","journal-title":"Oncogene"},{"key":"203_CR3","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/S0065-230X(08)60353-X","volume":"68","author":"M Henriksson","year":"1996","unstructured":"Henriksson M, Luscher B: Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res. 1996, 68: 109-182.","journal-title":"Adv Cancer Res"},{"key":"203_CR4","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1038\/nrc904","volume":"2","author":"S Pelengaris","year":"2002","unstructured":"Pelengaris S, Khan M, Evan G: c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002, 2: 764-776. 10.1038\/nrc904","journal-title":"Nat Rev Cancer"},{"key":"203_CR5","first-page":"1941","volume":"6","author":"T Moroy","year":"1991","unstructured":"Moroy T, Verbeek S, Ma A, Achacoso P, Berns A, Alt F: E mu N- and E mu L-myc cooperate with E mu pim-1 to generate lymphoid tumors at high frequency in double-transgenic mice. Oncogene. 1991, 6: 1941-1948.","journal-title":"Oncogene"},{"key":"203_CR6","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1002\/1097-0045(20000601)43:4<278::AID-PROS7>3.0.CO;2-4","volume":"43","author":"X Zhang","year":"2000","unstructured":"Zhang X, Lee C, Ng PY, Rubin M, Shabsigh A, Buttyan R: Prostatic neoplasia in transgenic mice with prostate-directed overexpression of the c-myc oncoprotein. Prostate. 2000, 43: 278-285. 10.1002\/1097-0045(20000601)43:4<278::AID-PROS7>3.0.CO;2-4","journal-title":"Prostate"},{"key":"203_CR7","doi-asserted-by":"publisher","first-page":"8300","DOI":"10.1074\/jbc.M211195200","volume":"278","author":"NA Jensen","year":"2003","unstructured":"Jensen NA, Pedersen KM, Lihme F, Rask L, Nielsen JV, Rasmussen TE, Mitchelmore C: Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas. J Biol Chem. 2003, 278: 8300-8308. 10.1074\/jbc.M211195200","journal-title":"J Biol Chem"},{"key":"203_CR8","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1126\/science.2006410","volume":"251","author":"EM Blackwood","year":"1991","unstructured":"Blackwood EM, Eisenman RN: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science. 1991, 251: 1211-1217. 10.1126\/science.2006410","journal-title":"Science"},{"key":"203_CR9","doi-asserted-by":"publisher","first-page":"2925","DOI":"10.1038\/sj.onc.1202747","volume":"18","author":"GF Claassen","year":"1999","unstructured":"Claassen GF, Hann SR: Myc-mediated transformation: the repression connection. Oncogene. 1999, 18: 2925-2933. 10.1038\/sj.onc.1202747","journal-title":"Oncogene"},{"key":"203_CR10","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/sj.emboj.7600509","volume":"24","author":"C Brenner","year":"2005","unstructured":"Brenner C, Deplus R, Didelot C, Loriot A, Vire E, De Smet C, Gutierrez A, Danovi D, Bernard D, Boon T, Pelicci PG, Amati B, Kouzarides T, de Launoit Y, Di Croce L, Fuks F: Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J. 2005, 24: 336-346. 10.1038\/sj.emboj.7600509","journal-title":"EMBO J"},{"key":"203_CR11","doi-asserted-by":"crossref","first-page":"5083","DOI":"10.1002\/j.1460-2075.1993.tb06202.x","volume":"12","author":"B Amati","year":"1993","unstructured":"Amati B, Littlewood TD, Evan GI, Land H: The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J. 1993, 12: 5083-5087.","journal-title":"EMBO J"},{"key":"203_CR12","first-page":"183","volume":"3","author":"M Bar-Ner","year":"1992","unstructured":"Bar-Ner M, Messing LT, Cultraro CM, Birrer MJ, Segal S: Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells. Cell Growth Differ. 1992, 3: 183-190.","journal-title":"Cell Growth Differ"},{"key":"203_CR13","doi-asserted-by":"publisher","first-page":"2916","DOI":"10.1038\/sj.onc.1202748","volume":"18","author":"MD Cole","year":"1999","unstructured":"Cole MD, McMahon SB: The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation. Oncogene. 1999, 18: 2916-2924. 10.1038\/sj.onc.1202748","journal-title":"Oncogene"},{"key":"203_CR14","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1128\/MCB.15.3.1536","volume":"15","author":"DE Brough","year":"1995","unstructured":"Brough DE, Hofmann TJ, Ellwood KB, Townley RA, Cole MD: An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation. Mol Cell Biol. 1995, 15: 1536-1544.","journal-title":"Mol Cell Biol"},{"key":"203_CR15","doi-asserted-by":"publisher","first-page":"7804","DOI":"10.1073\/pnas.90.16.7804","volume":"90","author":"C Bello-Fernandez","year":"1993","unstructured":"Bello-Fernandez C, Packham G, Cleveland JL: The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc Natl Acad Sci USA. 1993, 90: 7804-7808. 10.1073\/pnas.90.16.7804","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR16","doi-asserted-by":"publisher","first-page":"5757","DOI":"10.1073\/pnas.102173199","volume":"99","author":"D Levens","year":"2002","unstructured":"Levens D: Disentangling the MYC web. Proc Natl Acad Sci USA. 2002, 99: 5757-5759. 10.1073\/pnas.102173199","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR17","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1093\/emboj\/20.6.1383","volume":"20","author":"K Boon","year":"2001","unstructured":"Boon K, Caron HN, van Asperen R, Valentijn L, Hermus MC, van Sluis P, Roobeek I, Weis I, Voute PA, Schwab M, Versteeg R: N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J. 2001, 20: 1383-1393. 10.1093\/emboj\/20.6.1383","journal-title":"EMBO J"},{"key":"203_CR18","doi-asserted-by":"publisher","first-page":"3260","DOI":"10.1073\/pnas.97.7.3260","volume":"97","author":"HA Coller","year":"2000","unstructured":"Coller HA, Grandori C, Tamayo P, Colbert T, Lander ES, Eisenman RN, Golub TR: Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci USA. 2000, 97: 3260-3265. 10.1073\/pnas.97.7.3260","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR19","first-page":"5922","volume":"60","author":"QM Guo","year":"2000","unstructured":"Guo QM, Malek RL, Kim S, Chiao C, He M, Ruffy M, Sanka K, Lee NH, Dang CV, Liu ET: Identification of c-myc responsive genes using rat cDNA microarray. Cancer Res. 2000, 60: 5922-5928.","journal-title":"Cancer Res"},{"key":"203_CR20","doi-asserted-by":"publisher","first-page":"6274","DOI":"10.1073\/pnas.082005599","volume":"99","author":"A Menssen","year":"2002","unstructured":"Menssen A, Hermeking H: Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes. Proc Natl Acad Sci USA. 2002, 99: 6274-6279. 10.1073\/pnas.082005599","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR21","doi-asserted-by":"publisher","first-page":"3200","DOI":"10.1038\/sj.onc.1203636","volume":"19","author":"CE Nesbit","year":"2000","unstructured":"Nesbit CE, Tersak JM, Grove LE, Drzal A, Choi H, Prochownik EV: Genetic dissection of c-myc apoptotic pathways. Oncogene. 2000, 19: 3200-3212. 10.1038\/sj.onc.1203636","journal-title":"Oncogene"},{"key":"203_CR22","doi-asserted-by":"publisher","first-page":"6902","DOI":"10.1073\/pnas.0502081102","volume":"102","author":"D Remondini","year":"2005","unstructured":"Remondini D, O'Connell B, Intrator N, Sedivy JM, Neretti N, Castellani GC, Cooper LN: Targeting c-Myc-activated genes with a correlation method: detection of global changes in large gene expression network dynamics. Proc Natl Acad Sci USA. 2005, 102: 6902-6906. 10.1073\/pnas.0502081102","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR23","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1093\/nar\/29.2.397","volume":"29","author":"M Schuhmacher","year":"2001","unstructured":"Schuhmacher M, Kohlhuber F, Holzel M, Kaiser C, Burtscher H, Jarsch M, Bornkamm GW, Laux G, Polack A, Weidle UH, Eick D: The transcriptional program of a human B cell line in response to Myc. Nucleic Acids Res. 2001, 29: 397-406. 10.1093\/nar\/29.2.397","journal-title":"Nucleic Acids Res"},{"key":"203_CR24","doi-asserted-by":"publisher","first-page":"4984","DOI":"10.1038\/sj.onc.1204459","volume":"20","author":"O Schuldiner","year":"2001","unstructured":"Schuldiner O, Benvenisty N: A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors. Oncogene. 2001, 20: 4984-4994. 10.1038\/sj.onc.1204459","journal-title":"Oncogene"},{"key":"203_CR25","doi-asserted-by":"publisher","first-page":"36921","DOI":"10.1074\/jbc.M201493200","volume":"277","author":"JD Watson","year":"2002","unstructured":"Watson JD, Oster SK, Shago M, Khosravi F, Penn LZ: Identifying genes regulated in a Myc-dependent manner. J Biol Chem. 2002, 277: 36921-36930. 10.1074\/jbc.M201493200","journal-title":"J Biol Chem"},{"key":"203_CR26","unstructured":"Myc Cancer Gene., http:\/\/www.myc-cancer-gene.org\/"},{"key":"203_CR27","doi-asserted-by":"publisher","first-page":"R69","DOI":"10.1186\/gb-2003-4-10-r69","volume":"4","author":"KI Zeller","year":"2003","unstructured":"Zeller KI, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV: An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol. 2003, 4: R69- 10.1186\/gb-2003-4-10-r69","journal-title":"Genome Biol"},{"key":"203_CR28","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1002\/j.1460-2075.1995.tb07137.x","volume":"14","author":"S Gaubatz","year":"1995","unstructured":"Gaubatz S, Imhof A, Dosch R, Werner O, Mitchell P, Buettner R, Eilers M: Transcriptional activation by Myc is under negative control by the transcription factor AP-2. EMBO J. 1995, 14: 1508-1519.","journal-title":"EMBO J"},{"key":"203_CR29","doi-asserted-by":"publisher","first-page":"17834","DOI":"10.1073\/pnas.0604129103","volume":"103","author":"KI Zeller","year":"2006","unstructured":"Zeller KI, Zhao X, Lee CW, Chiu KP, Yao F, Yustein JT, Ooi HS, Orlov YL, Shahab A, Yong HC, Fu Y, Weng Z, Kuznetsov VA, Sung WK, Ruan Y, Dang CV, Wei CL: Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci USA. 2006, 103: 17834-17839. 10.1073\/pnas.0604129103","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR30","unstructured":"Gene Expression Omnibus (GEO)., http:\/\/www.myc-cancer-gene.org\/"},{"key":"203_CR31","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1038\/ng1532","volume":"37","author":"K Basso","year":"2005","unstructured":"Basso K, Margolin AA, Stolovitzky G, Klein U, Dalla-Favera R, Califano A: Reverse engineering of regulatory networks in human B cells. Nat Genet. 2005, 37: 382-390. 10.1038\/ng1532","journal-title":"Nat Genet"},{"key":"203_CR32","doi-asserted-by":"publisher","first-page":"e63","DOI":"10.1371\/journal.pcbi.0030063","volume":"3","author":"Y Chen","year":"2007","unstructured":"Chen Y, Blackwell TW, Chen J, Gao J, Lee AW, States DJ: Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function. PLoS Comput Biol. 2007, 3: e63- 10.1371\/journal.pcbi.0030063","journal-title":"PLoS Comput Biol"},{"key":"203_CR33","doi-asserted-by":"publisher","first-page":"36921","DOI":"10.1074\/jbc.M201493200","volume":"277","author":"JD Watson","year":"2002","unstructured":"Watson JD, Oster SK, Shago M, Khosravi F, Penn LZ: Identifying genes regulated in a Myc-dependent manner. J Biol Chem. 2002, 277: 36921-36930. 10.1074\/jbc.M201493200","journal-title":"J Biol Chem"},{"key":"203_CR34","doi-asserted-by":"publisher","first-page":"4878","DOI":"10.1093\/nar\/23.23.4878","volume":"23","author":"K Quandt","year":"1995","unstructured":"Quandt K, Frech K, Karas H, Wingender E, Werner T: MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 1995, 23: 4878-4884. 10.1093\/nar\/23.23.4878","journal-title":"Nucleic Acids Res"},{"key":"203_CR35","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1146\/annurev.pharmtox.39.1.103","volume":"39","author":"JP Whitlock Jr","year":"1999","unstructured":"Whitlock JP: Induction of cytochrome P4501A1. Annu Rev Pharmacol Toxicol. 1999, 39: 103-125. 10.1146\/annurev.pharmtox.39.1.103","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"203_CR36","doi-asserted-by":"publisher","first-page":"4955","DOI":"10.1093\/nar\/gkh816","volume":"32","author":"R Elkon","year":"2004","unstructured":"Elkon R, Zeller KI, Linhart C, Dang CV, Shamir R, Shiloh Y: In silico identification of transcriptional regulators associated with c-Myc. Nucleic Acids Res. 2004, 32: 4955-4961. 10.1093\/nar\/gkh816","journal-title":"Nucleic Acids Res"},{"key":"203_CR37","doi-asserted-by":"publisher","first-page":"11617","DOI":"10.1074\/jbc.R100063200","volume":"277","author":"RC Sears","year":"2002","unstructured":"Sears RC, Nevins JR: Signaling networks that link cell proliferation and cell fate. J Biol Chem. 2002, 277: 11617-11620. 10.1074\/jbc.R100063200","journal-title":"J Biol Chem"},{"key":"203_CR38","doi-asserted-by":"publisher","first-page":"3594","DOI":"10.1073\/pnas.86.10.3594","volume":"86","author":"SW Hiebert","year":"1989","unstructured":"Hiebert SW, Lipp M, Nevins JR: E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc Natl Acad Sci USA. 1989, 86: 3594-3598. 10.1073\/pnas.86.10.3594","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR39","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1101\/gad.8.13.1526","volume":"8","author":"KM Hsiao","year":"1994","unstructured":"Hsiao KM, McMahon SL, Farnham PJ: Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev. 1994, 8: 1526-1537. 10.1101\/gad.8.13.1526","journal-title":"Genes Dev"},{"key":"203_CR40","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1074\/jbc.M006074200","volume":"276","author":"F Wu","year":"2001","unstructured":"Wu F, Lee AS: YY1 as a regulator of replication-dependent hamster histone H3.2 promoter and an interactive partner of AP-2. J Biol Chem. 2001, 276: 28-34. 10.1074\/jbc.M006074200","journal-title":"J Biol Chem"},{"key":"203_CR41","doi-asserted-by":"publisher","first-page":"7877","DOI":"10.1128\/MCB.22.22.7877-7888.2002","volume":"22","author":"S Decary","year":"2002","unstructured":"Decary S, Decesse JT, Ogryzko V, Reed JC, Naguibneva I, Harel-Bellan A, Cremisi CE: The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2. Mol Cell Biol. 2002, 22: 7877-7888. 10.1128\/MCB.22.22.7877-7888.2002","journal-title":"Mol Cell Biol"},{"key":"203_CR42","doi-asserted-by":"publisher","first-page":"3767","DOI":"10.1093\/nar\/21.16.3767","volume":"21","author":"M Numoto","year":"1993","unstructured":"Numoto M, Niwa O, Kaplan J, Wong KK, Merrell K, Kamiya K, Yanagihara K, Calame K: Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins. Nucleic Acids Res. 1993, 21: 3767-3775. 10.1093\/nar\/21.16.3767","journal-title":"Nucleic Acids Res"},{"key":"203_CR43","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1093\/nar\/25.6.1108","volume":"25","author":"J Kaplan","year":"1997","unstructured":"Kaplan J, Calame K: The ZiN\/POZ domain of ZF5 is required for both transcriptional activation and repression. Nucleic Acids Res. 1997, 25: 1108-1116. 10.1093\/nar\/25.6.1108","journal-title":"Nucleic Acids Res"},{"key":"203_CR44","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1006\/bbrc.1998.8675","volume":"246","author":"K Yokoro","year":"1998","unstructured":"Yokoro K, Yanagidani A, Obata T, Yamamoto S, Numoto M: Genomic cloning and characterization of the mouse POZ\/zinc-finger protein ZF5. Biochem Biophys Res Commun. 1998, 246: 668-674. 10.1006\/bbrc.1998.8675","journal-title":"Biochem Biophys Res Commun"},{"key":"203_CR45","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1242\/dev.129.11.2723","volume":"129","author":"KS Imai","year":"2002","unstructured":"Imai KS, Satou Y, Satoh N: Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos. Development. 2002, 129: 2723-2732.","journal-title":"Development"},{"key":"203_CR46","doi-asserted-by":"publisher","first-page":"2334","DOI":"10.1038\/sj.onc.1204416","volume":"20","author":"EF Wagner","year":"2001","unstructured":"Wagner EF: AP-1 \u2013 Introductory remarks. Oncogene. 2001, 20: 2334-2335. 10.1038\/sj.onc.1204416","journal-title":"Oncogene"},{"key":"203_CR47","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1126\/science.7824938","volume":"267","author":"S Gupta","year":"1995","unstructured":"Gupta S, Campbell D, Derijard B, Davis RJ: Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science. 1995, 267: 389-393. 10.1126\/science.7824938","journal-title":"Science"},{"key":"203_CR48","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.molcel.2004.10.024","volume":"16","author":"J Hayakawa","year":"2004","unstructured":"Hayakawa J, Mittal S, Wang Y, Korkmaz KS, Adamson E, English C, Ohmichi M, McClelland M, Mercola D: Identification of promoters bound by c-Jun\/ATF2 during rapid large-scale gene activation following genotoxic stress. Mol Cell. 2004, 16: 521-535. 10.1016\/j.molcel.2004.10.024","journal-title":"Mol Cell"},{"key":"203_CR49","doi-asserted-by":"publisher","first-page":"8116","DOI":"10.1038\/sj.onc.1204966","volume":"20","author":"J Miethe","year":"2001","unstructured":"Miethe J, Schwartz C, Wottrich K, Wenning D, Klempnauer KH: Crosstalk between Myc and activating transcription factor 2 (ATF2): Myc prolongs the half-life and induces phosphorylation of ATF2. Oncogene. 2001, 20: 8116-8124. 10.1038\/sj.onc.1204966","journal-title":"Oncogene"},{"key":"203_CR50","doi-asserted-by":"publisher","first-page":"2590","DOI":"10.1038\/sj.emboj.7600742","volume":"24","author":"K Tamura","year":"2005","unstructured":"Tamura K, Hua B, Adachi S, Guney I, Kawauchi J, Morioka M, Tamamori-Adachi M, Tanaka Y, Nakabeppu Y, Sunamori M, Sedivy JM, Kitajima S: Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation. EMBO J. 2005, 24: 2590-2601. 10.1038\/sj.emboj.7600742","journal-title":"EMBO J"},{"key":"203_CR51","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1101\/gad.14.2.142","volume":"14","author":"KH Kaestner","year":"2000","unstructured":"Kaestner KH, Knochel W, Martinez DE: Unified nomenclature for the winged helix\/forkhead transcription factors. Genes Dev. 2000, 14: 142-146.","journal-title":"Genes Dev"},{"key":"203_CR52","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1006\/dbio.1998.9010","volume":"202","author":"M Mahlapuu","year":"1998","unstructured":"Mahlapuu M, Pelto-Huikko M, Aitola M, Enerback S, Carlsson P: FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces. Dev Biol. 1998, 202: 183-195. 10.1006\/dbio.1998.9010","journal-title":"Dev Biol"},{"key":"203_CR53","doi-asserted-by":"crossref","first-page":"L695","DOI":"10.1152\/ajplung.2001.280.4.L695","volume":"280","author":"VV Kalinichenko","year":"2001","unstructured":"Kalinichenko VV, Lim L, Shin B, Costa RH: Differential expression of forkhead box transcription factors following butylated hydroxytoluene lung injury. Am J Physiol Lung Cell Mol Physiol. 2001, 280: L695-L704.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"203_CR54","doi-asserted-by":"publisher","first-page":"2546","DOI":"10.1128\/MCB.24.6.2546-2559.2004","volume":"24","author":"JP Frederick","year":"2004","unstructured":"Frederick JP, Liberati NT, Waddell DS, Shi Y, Wang XF: Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. Mol Cell Biol. 2004, 24: 2546-2559. 10.1128\/MCB.24.6.2546-2559.2004","journal-title":"Mol Cell Biol"},{"key":"203_CR55","doi-asserted-by":"publisher","first-page":"18580","DOI":"10.1073\/pnas.0604773103","volume":"103","author":"SK Lim","year":"2006","unstructured":"Lim SK, Hoffmann FM: Smad4 cooperates with lymphoid enhancer-binding factor 1\/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proc Natl Acad Sci USA. 2006, 103: 18580-18585. 10.1073\/pnas.0604773103","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR56","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1006\/bbrc.1999.0856","volume":"260","author":"SG Ahn","year":"1999","unstructured":"Ahn SG, Cho GH, Jeong SY, Rhim H, Choi JY, Kim IK: Identification of cDNAs for Sox-4, an HMG-Box protein, and a novel human homolog of yeast splicing factor SSF-1 differentially regulated during apoptosis induced by prostaglandin A2\/delta12-PGJ2 in Hep3B cells. Biochem Biophys Res Commun. 1999, 260: 216-221. 10.1006\/bbrc.1999.0856","journal-title":"Biochem Biophys Res Commun"},{"key":"203_CR57","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1023\/A:1015773818302","volume":"57","author":"CJ Lee","year":"2002","unstructured":"Lee CJ, Appleby VJ, Orme AT, Chan WI, Scotting PJ: Differential expression of SOX4 and SOX11 in medulloblastoma. J Neurooncol. 2002, 57: 201-214. 10.1023\/A:1015773818302","journal-title":"J Neurooncol"},{"key":"203_CR58","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1016\/S0002-9440(10)64408-2","volume":"161","author":"HF Frierson Jr","year":"2002","unstructured":"Frierson HF, El Naggar AK, Welsh JB, Sapinoso LM, Su AI, Cheng J, Saku T, Moskaluk CA, Hampton GM: Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic carcinoma. Am J Pathol. 2002, 161: 1315-1323.","journal-title":"Am J Pathol"},{"key":"203_CR59","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1038\/ng956","volume":"32","author":"AH Lund","year":"2002","unstructured":"Lund AH, Turner G, Trubetskoy A, Verhoeven E, Wientjens E, Hulsman D, Russell R, DePinho RA, Lenz J, van Lohuizen M: Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice. Nat Genet. 2002, 32: 160-165. 10.1038\/ng956","journal-title":"Nat Genet"},{"key":"203_CR60","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1038\/ng949","volume":"32","author":"T Suzuki","year":"2002","unstructured":"Suzuki T, Shen H, Akagi K, Morse HC, Malley JD, Naiman DQ, Jenkins NA, Copeland NG: New genes involved in cancer identified by retroviral tagging. Nat Genet. 2002, 32: 166-174. 10.1038\/ng949","journal-title":"Nat Genet"},{"key":"203_CR61","doi-asserted-by":"publisher","first-page":"4994","DOI":"10.1093\/nar\/29.24.4994","volume":"29","author":"H Braun","year":"2001","unstructured":"Braun H, Koop R, Ertmer A, Nacht S, Suske G: Transcription factor Sp3 is regulated by acetylation. Nucleic Acids Res. 2001, 29: 4994-5000. 10.1093\/nar\/29.24.4994","journal-title":"Nucleic Acids Res"},{"key":"203_CR62","doi-asserted-by":"publisher","first-page":"16503","DOI":"10.1021\/bi00050a034","volume":"34","author":"MJ Birnbaum","year":"1995","unstructured":"Birnbaum MJ, van Wijnen AJ, Odgren PR, Last TJ, Suske G, Stein GS, Stein JL: Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. Biochemistry. 1995, 34: 16503-16508. 10.1021\/bi00050a034","journal-title":"Biochemistry"},{"key":"203_CR63","doi-asserted-by":"publisher","first-page":"6740","DOI":"10.1158\/0008-5472.CAN-04-0713","volume":"64","author":"M Abdelrahim","year":"2004","unstructured":"Abdelrahim M, Smith R, Burghardt R, Safe S: Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells. Cancer Res. 2004, 64: 6740-6749. 10.1158\/0008-5472.CAN-04-0713","journal-title":"Cancer Res"},{"key":"203_CR64","doi-asserted-by":"publisher","first-page":"2474","DOI":"10.1038\/sj.onc.1203527","volume":"19","author":"T Bowman","year":"2000","unstructured":"Bowman T, Garcia R, Turkson J, Jove R: STATs in oncogenesis. Oncogene. 2000, 19: 2474-2488. 10.1038\/sj.onc.1203527","journal-title":"Oncogene"},{"key":"203_CR65","doi-asserted-by":"publisher","first-page":"10750","DOI":"10.1158\/0008-5472.CAN-05-2399","volume":"65","author":"D Tantin","year":"2005","unstructured":"Tantin D, Schild-Poulter C, Wang V, Hache RJ, Sharp PA: The octamer binding transcription factor Oct-1 is a stress sensor. Cancer Res. 2005, 65: 10750-10758. 10.1158\/0008-5472.CAN-05-2399","journal-title":"Cancer Res"},{"key":"203_CR66","doi-asserted-by":"publisher","first-page":"G266","DOI":"10.1152\/ajpgi.00486.2001","volume":"283","author":"RA Gupta","year":"2002","unstructured":"Gupta RA, Dubois RN: Controversy: PPARgamma as a target for treatment of colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2002, 283: G266-G269.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"203_CR67","doi-asserted-by":"publisher","first-page":"98","DOI":"10.2337\/diab.47.1.98","volume":"47","author":"AM Lefebvre","year":"1998","unstructured":"Lefebvre AM, Laville M, Vega N, Riou JP, van Gaal L, Auwerx J, Vidal H: Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes. 1998, 47: 98-103. 10.2337\/diabetes.47.1.98","journal-title":"Diabetes"},{"key":"203_CR68","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1054\/bjoc.2000.1457","volume":"83","author":"H Sato","year":"2000","unstructured":"Sato H, Ishihara S, Kawashima K, Moriyama N, Suetsugu H, Kazumori H, Okuyama T, Rumi MA, Fukuda R, Nagasue N, Kinoshita Y: Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. Br J Cancer. 2000, 83: 1394-1400. 10.1054\/bjoc.2000.1457","journal-title":"Br J Cancer"},{"key":"203_CR69","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/sj.cdd.4401000","volume":"9","author":"N Yamakawa-Karakida","year":"2002","unstructured":"Yamakawa-Karakida N, Sugita K, Inukai T, Goi K, Nakamura M, Uno K, Sato H, Kagami K, Barker N, Nakazawa S: Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity. Cell Death Differ. 2002, 9: 513-526. 10.1038\/sj.cdd.4401000","journal-title":"Cell Death Differ"},{"key":"203_CR70","doi-asserted-by":"publisher","first-page":"9375","DOI":"10.1128\/MCB.23.24.9375-9388.2003","volume":"23","author":"MJ McConnell","year":"2003","unstructured":"McConnell MJ, Chevallier N, Berkofsky-Fessler W, Giltnane JM, Malani RB, Staudt LM, Licht JD: Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Mol Cell Biol. 2003, 23: 9375-9388. 10.1128\/MCB.23.24.9375-9388.2003","journal-title":"Mol Cell Biol"},{"key":"203_CR71","doi-asserted-by":"publisher","first-page":"5490","DOI":"10.1128\/MCB.20.15.5490-5502.2000","volume":"20","author":"LJ Wood","year":"2000","unstructured":"Wood LJ, Mukherjee M, Dolde CE, Xu Y, Maher JF, Bunton TE, Williams JB, Resar LM: HMG-I\/Y, a new c-Myc target gene and potential oncogene. Mol Cell Biol. 2000, 20: 5490-5502. 10.1128\/MCB.20.15.5490-5502.2000","journal-title":"Mol Cell Biol"},{"key":"203_CR72","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/0092-8674(95)90137-X","volume":"83","author":"JV Falvo","year":"1995","unstructured":"Falvo JV, Thanos D, Maniatis T: Reversal of intrinsic DNA bends in the IFN beta gene enhancer by transcription factors and the architectural protein HMG I(Y). Cell. 1995, 83: 1101-1111. 10.1016\/0092-8674(95)90137-X","journal-title":"Cell"},{"key":"203_CR73","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1002\/j.1460-2075.1993.tb05993.x","volume":"12","author":"K Zhao","year":"1993","unstructured":"Zhao K, Kas E, Gonzalez E, Laemmli UK: SAR-dependent mobilization of histone H1 by HMG-I\/Y in vitro: HMG-I\/Y is enriched in H1-depleted chromatin. EMBO J. 1993, 12: 3237-3247.","journal-title":"EMBO J"},{"key":"203_CR74","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/bjc.1996.403","volume":"74","author":"Y Tamimi","year":"1996","unstructured":"Tamimi Y, Poel van der HG, Karthaus HF, Debruyne FM, Schalken JA: A retrospective study of high mobility group protein I(Y) as progression marker for prostate cancer determined by in situ hybridization. Br J Cancer. 1996, 74: 573-578.","journal-title":"Br J Cancer"},{"key":"203_CR75","doi-asserted-by":"publisher","first-page":"3459","DOI":"10.1242\/jcs.01160","volume":"117","author":"M Harrer","year":"2004","unstructured":"Harrer M, Luhrs H, Bustin M, Scheer U, Hock R: Dynamic interaction of HMGA1a proteins with chromatin. Journal of Cell Science. 2004, 117: 3459-3471. 10.1242\/jcs.01160","journal-title":"Journal of Cell Science"},{"key":"203_CR76","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1002\/jcb.20012","volume":"91","author":"T Hsu","year":"2004","unstructured":"Hsu T, Trojanowska M, Watson DK: Ets proteins in biological control and cancer. J Cell Biochem. 2004, 91: 896-903. 10.1002\/jcb.20012","journal-title":"J Cell Biochem"},{"key":"203_CR77","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/S0378-1119(02)01156-3","volume":"303","author":"T Oikawa","year":"2003","unstructured":"Oikawa T, Yamada T: Molecular biology of the Ets family of transcription factors. Gene. 2003, 303: 11-34. 10.1016\/S0378-1119(02)01156-3","journal-title":"Gene"},{"key":"203_CR78","unstructured":"UCSC Genome Bioinformatics., http:\/\/genome.ucsc.edu\/"},{"key":"203_CR79","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1093\/hmg\/11.16.1817","volume":"11","author":"SL Coleman","year":"2002","unstructured":"Coleman SL, Buckland PR, Hoogendoorn B, Guy C, Smith K, O'Donovan MC: Experimental analysis of the annotation of promoters in the public database. Hum Mol Genet. 2002, 11: 1817-1821. 10.1093\/hmg\/11.16.1817","journal-title":"Hum Mol Genet"},{"key":"203_CR80","doi-asserted-by":"publisher","first-page":"8164","DOI":"10.1073\/pnas.1332764100","volume":"100","author":"Z Li","year":"2003","unstructured":"Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B: A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci USA. 2003, 100: 8164-8169. 10.1073\/pnas.1332764100","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR81","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1093\/nar\/gkl1157","volume":"35","author":"F Parisi","year":"2007","unstructured":"Parisi F, Wirapati P, Naef F: Identifying synergistic regulation involving c-Myc and sp1 in human tissues. Nucleic Acids Res. 2007, 35: 1098-1107. 10.1093\/nar\/gkl1157","journal-title":"Nucleic Acids Res"},{"key":"203_CR82","doi-asserted-by":"publisher","first-page":"5313","DOI":"10.1073\/pnas.0931346100","volume":"100","author":"TJ Haggerty","year":"2003","unstructured":"Haggerty TJ, Zeller KI, Osthus RC, Wonsey DR, Dang CV: A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites. Proc Natl Acad Sci USA. 2003, 100: 5313-5318. 10.1073\/pnas.0931346100","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR83","unstructured":"BIOBASE Biological Databases., http:\/\/www.biobase-international.com\/pages\/"},{"key":"203_CR84","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1093\/nar\/29.1.281","volume":"29","author":"E Wingender","year":"2001","unstructured":"Wingender E, Chen X, Fricke E, Geffers R, Hehl R, Liebich I, Krull M, Matys V, Michael H, Ohnhauser R, Pruss M, Schacherer F, Thiele S, Urbach S: The TRANSFAC system on gene expression regulation. Nucleic Acids Res. 2001, 29: 281-283. 10.1093\/nar\/29.1.281","journal-title":"Nucleic Acids Res"},{"key":"203_CR85","doi-asserted-by":"publisher","first-page":"3576","DOI":"10.1093\/nar\/gkg585","volume":"31","author":"AE Kel","year":"2003","unstructured":"Kel AE, Gossling E, Reuter I, Cheremushkin E, Kel-Margoulis OV, Wingender E: MATCH: A tool for searching transcription factor binding sites in DNA sequences. Nucleic Acids Res. 2003, 31: 3576-3579. 10.1093\/nar\/gkg585","journal-title":"Nucleic Acids Res"}],"container-title":["BMC Systems Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-0509-2-46.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-0509-2-46\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-0509-2-46.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:20:52Z","timestamp":1684416052000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsystbiol.biomedcentral.com\/articles\/10.1186\/1752-0509-2-46"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,22]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["203"],"URL":"https:\/\/doi.org\/10.1186\/1752-0509-2-46","relation":{},"ISSN":["1752-0509"],"issn-type":[{"value":"1752-0509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,22]]},"article-number":"46"}}