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Here we provide a mathematical conceptualization of our current knowledge of the tanning response, in terms of a dynamic model. The resolution level of the model is tuned to available data, and its primary focus is to describe the tanning response following UV exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The model appears capable of accounting for available experimental data on the tanning response in different skin and photo types. It predicts that the thickness of the epidermal layer and how far the melanocyte dendrites grow out in the epidermal layers after UV exposure influence the tanning response substantially.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the paucity of experimental validation data the model is constrained enough to serve as a foundation for the establishment of a theoretical-experimental research programme aimed at elucidating the more fine-grained regulatory anatomy underlying the tanning response.<\/jats:p><\/jats:sec>","DOI":"10.1186\/1752-0509-3-60","type":"journal-article","created":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T18:13:32Z","timestamp":1244571212000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The mathematics of tanning"],"prefix":"10.1186","volume":"3","author":[{"given":"Josef","family":"Thingnes","sequence":"first","affiliation":[]},{"given":"Leiv","family":"\u00d8yehaug","sequence":"additional","affiliation":[]},{"given":"Eivind","family":"Hovig","sequence":"additional","affiliation":[]},{"given":"Stig W","family":"Omholt","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2009,6,9]]},"reference":[{"key":"328_CR1","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1146\/annurev.anthro.33.070203.143955","volume":"33","author":"NG Jablonski","year":"2004","unstructured":"Jablonski NG: The evolution of human skin and skin color. 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