{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T15:47:14Z","timestamp":1742399234417},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"S2","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Syst Biol"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1186\/1752-0509-4-s2-s14","type":"journal-article","created":{"date-parts":[[2010,9,14]],"date-time":"2010-09-14T06:15:35Z","timestamp":1284444935000},"source":"Crossref","is-referenced-by-count":12,"title":["On finite-horizon control of genetic regulatory networks with multiple hard-constraints"],"prefix":"10.1186","volume":"4","author":[{"given":"Cong","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching","family":"Wai-Ki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsing","family":"Nam-Kiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leung","family":"Ho-Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,9,13]]},"reference":[{"key":"544_CR1","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s001090050329","volume":"77","author":"S Huang","year":"1999","unstructured":"Huang S: Gene Expression Profiling, Genetic Networks, and Cellular States: An Integrating Concept for Tumorigenesis and Drug Discovery. J. Mol. Med. 1999, 77: 169-480. 10.1007\/s001090050329","journal-title":"J. Mol. Med"},{"key":"544_CR2","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/224177a0","volume":"224","author":"S Kauffman","year":"1969","unstructured":"Kauffman S: Homeostasis and Differentiation in Random Genetic Control Networks. Nature. 1969, 224: 177-178. 10.1038\/224177a0","journal-title":"Nature"},{"key":"544_CR3","volume-title":"Journal of Artificial Intelligence in Medicine","author":"S Zhang","year":"2010","unstructured":"Zhang S, Ching W, Tsing N, Leung H, Guo D: A Multiple Regression Approach for Construction of Genetic Regulatory Networks. Journal of Artificial Intelligence in Medicine. 2010"},{"key":"544_CR4","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1093\/bioinformatics\/18.2.261","volume":"18","author":"I Shmulevich","year":"2002","unstructured":"Shmulevich I, Dougherty E, Kim S, Zhang W: Probabilistic Boolean Networks: A Rulebased Uncertainty Model for Gene Regulatory Networks. Bioinformatics. 2002, 18: 261-274. 10.1093\/bioinformatics\/18.2.261","journal-title":"Bioinformatics"},{"key":"544_CR5","doi-asserted-by":"crossref","DOI":"10.1515\/9781400865260","volume-title":"Genomic Signal Processing","author":"I Shmulevich","year":"2007","unstructured":"Shmulevich I, Dougherty E: Genomic Signal Processing. 2007, New York: Princeton University Press, first edition","edition":"first edition"},{"key":"544_CR6","first-page":"69","volume":"9","author":"HD Jong","year":"2002","unstructured":"Jong HD: Modeling and Simulation of Genetic Regulatory Systems: A Literature Review. J. Comp. Biol. 2002, 9: 69-103.","journal-title":"J. Comp. Biol"},{"key":"544_CR7","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1016\/S0896-6273(00)81194-0","volume":"26","author":"P Smolen","year":"2000","unstructured":"Smolen P, Baxter D, Byrne J: Mathematical Modeling of Gene Network. Neuron. 2000, 26: 1319-1331. 10.1016\/S0896-6273(00)81194-0.","journal-title":"Neuron"},{"key":"544_CR8","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195079517.001.0001","volume-title":"The Origins of Order: Self-organization and, Selection in Evolution","author":"S Kauffman","year":"1993","unstructured":"Kauffman S: The Origins of Order: Self-organization and, Selection in Evolution. 1993, New York: Oxford Univ. Press, first","edition":"first"},{"key":"544_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/excr.2000.5044","volume":"261","author":"S Huang","year":"2000","unstructured":"Huang S, Ingber D: Shape-dependent Control of Cell Growth, Differentiation, and Apoptosis: Switching Between Attractors in Cell Regulatory Networks. Exp. Cell Res. 2000, 261: 1-103. 10.1006\/excr.2000.5044","journal-title":"Exp. Cell Res"},{"key":"544_CR10","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1016\/S0165-1684(00)00079-7","volume":"80","author":"E Dougherty","year":"2000","unstructured":"Dougherty E, Kim S, Chen Y: Coefficient of Determination in Nonlinear Signal Processing. Signal Processing. 2000, 80: 2219-2235. 10.1016\/S0165-1684(00)00079-7.","journal-title":"Signal Processing"},{"key":"544_CR11","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1093\/bioinformatics\/btm142","volume":"23","author":"W Ching","year":"2007","unstructured":"Ching W, Zhang S, Ng M, Akutsu T: An Approximation Method for Solving the Steady-state Probability Distribution of Probabilistic Boolean Networks. Bioinformatics. 2007, 23: 1511-1518. 10.1093\/bioinformatics\/btm142","journal-title":"Bioinformatics"},{"key":"544_CR12","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1093\/bioinformatics\/18.10.1319","volume":"18","author":"I Shmulevich","year":"2002","unstructured":"Shmulevich I, Dougherty E, Zhang W: Gene Perturbation and Intervention in Probabilistic Boolean Networks. Bioinformatis. 2002, 18: 1319-1331. 10.1093\/bioinformatics\/18.10.1319.","journal-title":"Bioinformatis"},{"key":"544_CR13","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1142\/S0218339002000706","volume":"10","author":"I Shmulevich","year":"2002","unstructured":"Shmulevich I, Dougherty E, Kim S, Zhang W: Control of Stationary Behavior in Probabilistic Boolean Networks by Means of Structural Intervention. Journal of Biological Systems. 2002, 10: 431-445. 10.1142\/S0218339002000706.","journal-title":"Journal of Biological Systems"},{"key":"544_CR14","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1023\/A:1023909812213","volume":"52","author":"A Datta","year":"2003","unstructured":"Datta A, Choudhary A, Bitter M, Dougherty E: External Control in Markovian Genetic Regulatory Networks. Machine Learning. 2003, 52: 169-191. 10.1023\/A:1023909812213.","journal-title":"Machine Learning"},{"key":"544_CR15","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1093\/bioinformatics\/bti131","volume":"21","author":"R Pal","year":"2005","unstructured":"Pal R, Datta A, Bittner M, Dougherty E: Intervention in Context-sensitive Probabilistic Boolean Networks. Bioinformatics. 2005, 21: 1211-1218. 10.1093\/bioinformatics\/bti131","journal-title":"Bioinformatics"},{"key":"544_CR16","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1109\/TSP.2006.873740","volume":"54","author":"R Pal","year":"2006","unstructured":"Pal R, Dougherty E: Optimal Infinite Horizon Control for Probabilistic Boolean Networks. IEEE Transactions on Signal Processing. 2006, 54: 2375-2387. 10.1109\/TSP.2006.873740.","journal-title":"IEEE Transactions on Signal Processing"},{"key":"544_CR17","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.biosystems.2006.12.005","volume":"90","author":"P Chen","year":"2006","unstructured":"Chen P, Chen J: A Markovian Approach to the Control of Genetic Regulatory Networks. Biosystems. 2006, 90: 535-545. 10.1016\/j.biosystems.2006.12.005","journal-title":"Biosystems"},{"key":"544_CR18","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1049\/iet-syb.2008.0120","volume":"3","author":"W Ching","year":"2009","unstructured":"Ching W, Zhang S, Jiao Y, Akutsu T, Wong A: Optimal Control Policy for Probabilistic Boolean Networks with Hard Constraints. IET on Systems Biology. 2009, 3: 90-99. 10.1049\/iet-syb.2008.0120.","journal-title":"IET on Systems Biology"},{"key":"544_CR19","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/j.jtbi.2006.09.023","volume":"244","author":"T Akutsu","year":"2007","unstructured":"Akutsu T, Hayasida M, Ching W, Ng M: Control of Boolean Networks: Hardness Results and Algorithms for Tree Structured Networks. Journal of Theoretical Biology. 2007, 244: 670-679. 10.1016\/j.jtbi.2006.09.023","journal-title":"Journal of Theoretical Biology"},{"key":"544_CR20","first-page":"33","volume":"11","author":"W Ching","year":"2009","unstructured":"Ching W, Cong Y: Finite-Horizon Control of Genetic Regulatory Networks with Multiple Hard-Constraints. Lecture Notes in Operations Research. 2009, 11: 33-40.","journal-title":"Lecture Notes in Operations Research"}],"container-title":["BMC Systems Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-0509-4-S2-S14.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-0509-4-S2-S14\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-0509-4-S2-S14.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T11:42:46Z","timestamp":1711798966000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcsystbiol.biomedcentral.com\/articles\/10.1186\/1752-0509-4-S2-S14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":20,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["544"],"URL":"https:\/\/doi.org\/10.1186\/1752-0509-4-s2-s14","relation":{},"ISSN":["1752-0509"],"issn-type":[{"value":"1752-0509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9]]},"article-number":"S14"}}