{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T18:03:23Z","timestamp":1759514603651},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T00:00:00Z","timestamp":1315526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T00:00:00Z","timestamp":1315526400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chemistry Central Journal"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1186\/1752-153x-5-52","type":"journal-article","created":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T23:16:25Z","timestamp":1315610185000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin"],"prefix":"10.1186","volume":"5","author":[{"given":"Juliana","family":"Ivanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivayla N","family":"Pantcheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Mitewa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Simova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Tanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohtaro","family":"Osakada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,9,9]]},"reference":[{"key":"316_CR1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.2307\/3280218","volume":"65","author":"LR Chappel","year":"1979","unstructured":"Chappel LR: The site of action of the anticoccidial salinomycin (Coxistac). J Parasitol. 1979, 65: 137-143. 10.2307\/3280218.","journal-title":"J Parasitol"},{"key":"316_CR2","first-page":"103","volume-title":"Polyether antibitocis: naturally occuring acid ionophores","author":"RW Taylor","year":"1982","unstructured":"Taylor RW, Kauffman RF, Pfeiffer DR: Cation complexation and transport by carboxylic ionophores. Polyether antibitocis: naturally occuring acid ionophores. Edited by: Westley. 1982, New York: Marcel Dekker, 103-184."},{"key":"316_CR3","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.7164\/antibiotics.36.1195","volume":"36","author":"JW Westley","year":"1983","unstructured":"Westley JW, Liu CM, Evans RH, Sello LH, Troupe N, Hermann T: Preparation, properties and biological activity of natural and semisynthetic urethanes of monensin. J Antibiot (Tokyo). 1983, 36: 1195-1200.","journal-title":"J Antibiot (Tokyo)"},{"key":"316_CR4","doi-asserted-by":"publisher","first-page":"451","DOI":"10.3109\/01480548509041069","volume":"8","author":"SC Gad","year":"1985","unstructured":"Gad SC, Reilly C, Siino K, Gavigan FA, Witz G: Thirteen cationic ionophores: their acute toxicity, neurobehavioral and membrane effects. Drug Chem Toxicol. 1985, 8: 451-468. 10.3109\/01480548509041069.","journal-title":"Drug Chem Toxicol"},{"key":"316_CR5","doi-asserted-by":"publisher","first-page":"29","DOI":"10.2307\/3282340","volume":"73","author":"SD Folz","year":"1987","unstructured":"Folz SD, Nowakowski LH, Lee BL, Conder GA, Rector DL, Brodasky TF: Anticoccidial activity of alborixin. J Parasitol. 1987, 73: 29-35. 10.2307\/3282340.","journal-title":"J Parasitol"},{"key":"316_CR6","doi-asserted-by":"publisher","first-page":"960","DOI":"10.3382\/ps.0660960","volume":"66","author":"PC Augustine","year":"1987","unstructured":"Augustine PC, Smith CK, Danforth HD, Ruff MD: Effect of ionophorous anticoccidials on invasion and development of Eimeria: comparison of sensitive and resistant isolates and correlation with drug uptake. Poult Sci. 1987, 66: 960-965.","journal-title":"Poult Sci"},{"key":"316_CR7","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.3382\/ps.0722058","volume":"72","author":"NB Logan","year":"1993","unstructured":"Logan NB, McKenzie ME, Conway DP, Chappel LR, Hammet NC: Anticoccidial efficacy of semduramicin. 2. Evaluation against field isolates including comparisons with salinomycin, maduramicin, and monensin in battery tests. Poult Sci. 1993, 72: 2058-2063.","journal-title":"Poult Sci"},{"key":"316_CR8","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0306-3623(98)00271-7","volume":"33","author":"H Satoh","year":"1999","unstructured":"Satoh H, Tsuchida K: Pharmacological actions of monovalent ionophores on spontaneously beating rabbit sino-atrial nodal cells. Gen Pharmacol. 1999, 33: 151-159. 10.1016\/S0306-3623(98)00271-7.","journal-title":"Gen Pharmacol"},{"key":"316_CR9","volume-title":"The role of enteric antibiotics in livestock production","author":"SV Page","year":"2003","unstructured":"Page SV: The role of enteric antibiotics in livestock production. 2003, Canberra, Australia: Avcare Ltd"},{"key":"316_CR10","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1002\/hlca.19710540419","volume":"54","author":"WK Lutz","year":"1971","unstructured":"Lutz WK, Winkler FK, Dunitz JD: Crystal structure of the antibiotic Monensin. Similarities and differences between free acid and metal complex. Helv Chim Acta. 1971, 54: 1103-1108. 10.1002\/hlca.19710540419.","journal-title":"Helv Chim Acta"},{"key":"316_CR11","doi-asserted-by":"crossref","unstructured":"Kinashi H, Otake N, Yonehara H, Sato S, Saito Y: Studies on the ionophorous antibiotics. I. The crystal and molecular structure of salinomycin p-iodophenacyl ester. Acta Cryst. 1975, 2411-2415. B31","DOI":"10.1107\/S0567740875007716"},{"key":"316_CR12","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/BF00651699","volume":"12","author":"Y Pointud","year":"1983","unstructured":"Pointud Y, Tissier C, Juillard J: Neutral and charged complexes of aklali metal cations with the ionophore nigericin in methanol. A thermodynamic study. J Sol Chem. 1983, 12: 473-485. 10.1007\/BF00651699.","journal-title":"J Sol Chem"},{"key":"316_CR13","doi-asserted-by":"publisher","first-page":"5467","DOI":"10.1021\/j150644a032","volume":"87","author":"J Garcla-Rosas","year":"1983","unstructured":"Garcla-Rosas J, Schneider H, Cox BG: Silver complexation by the ionophorous antibiotic monensin in nonaqueous solvents. J Phys Chem. 1983, 87: 5467-5472. 10.1021\/j150644a032.","journal-title":"J Phys Chem"},{"key":"316_CR14","doi-asserted-by":"publisher","first-page":"5965","DOI":"10.1021\/ja00332a035","volume":"106","author":"BG Cox","year":"1984","unstructured":"Cox BG, Vantruong N, Rzeszotarska J, Schneider H: Rates and equilibria of alkali-metal and silver ion complex-formation with monensin in ethanol. J Am Chem Soc. 1984, 106: 5965-5969. 10.1021\/ja00332a035.","journal-title":"J Am Chem Soc"},{"key":"316_CR15","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1021\/jo00352a023","volume":"51","author":"DM Walba","year":"1986","unstructured":"Walba DM, Hermsmeier M, Haltiwanger RC, Noordik JH: Crystal structures of monensin B lithium and silver salts. J Org Chem. 1986, 51: 245-247. 10.1021\/jo00352a023.","journal-title":"J Org Chem"},{"key":"316_CR16","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1021\/ja00241a038","volume":"109","author":"W Pangborn","year":"1987","unstructured":"Pangborn W, Duax WL, Langs D: The hydrated potassium complex of the ionophore monensin A. J Am Chem Soc. 1987, 109: 163-2165.","journal-title":"J Am Chem Soc"},{"key":"316_CR17","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1007\/BF00648581","volume":"22","author":"M Mimouni","year":"1993","unstructured":"Mimouni M, Perrier S, Pointud Y, Juillard J: Selectivity of bacterial ionophore monensin for monovalent metal cations - solvent effects in methanol and biphasic water-organic systems. J Sol Chem. 1993, 22: 769-785. 10.1007\/BF00648581.","journal-title":"J Sol Chem"},{"key":"316_CR18","unstructured":"Mimouni M, Hebrant M, Dauphin G, Juillard J: Monovalent cation salts of the bacterial ionophore monensin in methanol. Structural aspects from NMR experiments. J Chem Res. 1996, 278-279. S6"},{"key":"316_CR19","first-page":"1154","volume":"101","author":"E Wagner-Czauderna","year":"1997","unstructured":"Wagner-Czauderna E, Rzeszotarska J, Orlowska E, Kalinowski MK: Complexing ability of monensin anion for alkali metal cations in binary mixtures of dipolar aprotic solvents. Phys Chem Chem Phys. 1997, 101: 1154-1157.","journal-title":"Phys Chem Chem Phys"},{"key":"316_CR20","doi-asserted-by":"publisher","first-page":"8209","DOI":"10.1021\/ja973607x","volume":"120","author":"EF Paulus","year":"1998","unstructured":"Paulus EF, Kurz M, Matter H, Vertesy L: Solid-state and solution structure of the salinomycin-sodium complex: Stabilization of different conformers for an ionophore in different environments. J Am Chem Soc. 1998, 120: 8209-8221. 10.1021\/ja973607x.","journal-title":"J Am Chem Soc"},{"key":"316_CR21","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1002\/chir.10052","volume":"14","author":"FG Riddell","year":"2002","unstructured":"Riddell FG: Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics. Chirality. 2002, 14: 121-125. 10.1002\/chir.10052.","journal-title":"Chirality"},{"key":"316_CR22","doi-asserted-by":"crossref","unstructured":"Paz FAA, Gates PJ, Fowler S, Gallimore A, Harvey B, Lopes NP, Stark CBW, Staunton J, Klinowski J, Spencer JB: Sodium monensin dihydrate. Acta Cryst. 2003, m1050-m1052. E59","DOI":"10.1107\/S1600536803022980"},{"key":"316_CR23","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jinorgbio.2007.06.033","volume":"102","author":"P Dorkov","year":"2008","unstructured":"Dorkov P, Pantcheva IN, Sheldrick WS, Mayer-Figge H, Petrova R, Mitewa M: Synthesis, structure and antimicrobial activity of manganese(II) and cobalt(II) complexes of the polyether ionophore antibiotic sodium monensin A. J Inorg Biochem. 2008, 102: 26-32. 10.1016\/j.jinorgbio.2007.06.033.","journal-title":"J Inorg Biochem"},{"key":"316_CR24","doi-asserted-by":"publisher","first-page":"154","DOI":"10.2174\/157016308784746247","volume":"5","author":"IN Pantcheva","year":"2008","unstructured":"Pantcheva IN, Mitewa M, Sheldrick WS, Oppel IM, Zhorova R, Dorkov P: First divalent metal complexes of the polyether ionophore Monensin A: X-ray structures of [Co(Mon)2(H2O)2] and [Mn(Mon)2(H2O)2] and their properties. Curr Drug Discov Techn. 2008, 5: 154-161. 10.2174\/157016308784746247.","journal-title":"Curr Drug Discov Techn"},{"key":"316_CR25","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1016\/j.jinorgbio.2009.08.007","volume":"103","author":"IN Pantcheva","year":"2009","unstructured":"Pantcheva IN, Dorkov P, Atanasov V, Mitewa M, Shivachev BL, Nikolova RP, Mayer-Figge H, Sheldrick WS: Crystal structure and properties of the copper(II) complex of sodium monensin A. J Inorg Biochem. 2009, 103: 1419-1424. 10.1016\/j.jinorgbio.2009.08.007.","journal-title":"J Inorg Biochem"},{"key":"316_CR26","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1016\/j.ica.2010.02.009","volume":"363","author":"IN Pantcheva","year":"2010","unstructured":"Pantcheva IN, Ivanova J, Zhorova R, Mitewa M, Simova S, Mayer-Figge H, Sheldrick WS: Nickel(II) and zinc(II) dimonensinates: crystal structure, spectral properties and bactericidal activity. Inorg Chim Acta. 2010, 363: 1879-1886. 10.1016\/j.ica.2010.02.009.","journal-title":"Inorg Chim Acta"},{"key":"316_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s10534-009-9269-5","volume":"23","author":"IN Pantcheva","year":"2009","unstructured":"Pantcheva IN, Zhorova R, Mitewa M, Simova S, Mayer-Figge H, Sheldrick WS: X-ray crystal structure of [M(Mon)2(H2O)2] (M = Mg, Ca), spectral properties and cytotoxicity against Gram-positive bacteria. Biometals. 2009, 23: 59-70.","journal-title":"Biometals"},{"key":"316_CR28","doi-asserted-by":"publisher","first-page":"852","DOI":"10.2478\/s11532-010-0067-2","volume":"8","author":"J Ivanova","year":"2010","unstructured":"Ivanova J, Pantcheva IN, Mitewa M, Simova S, Mayer-Figge H, Sheldrick WS: Crystal structures and spectral properties of new Cd(II) and Hg(II) complexes of monensic acid with different coordination modes of the ligand. Centr Eur J Chem. 2010, 8: 852-860. 10.2478\/s11532-010-0067-2.","journal-title":"Centr Eur J Chem"},{"key":"316_CR29","first-page":"439","volume-title":"Recent Researches in Modern Medicine","author":"M Mitewa","year":"2011","unstructured":"Mitewa M, Pantcheva I, Alexandrova R: Antitumor activity of the polyether ionophorous antibiotic monensin and its metal(II) complexes. Recent Researches in Modern Medicine. Edited by: Braissant O, Wakamatsu H, Kuo-Kang I, Allegaert K, Lenbury Y, Wachholtz A. 2011, Cambridge: WSEAS Press, 439-444."},{"key":"316_CR30","first-page":"93","volume":"5","author":"R Alexandrova","year":"2011","unstructured":"Alexandrova R, Zhivkova T, Pantcheva IN, Mitewa M: Cytotoxic and antiproliferative activities of monensic acid and its metal(II) complexes against drug sensitive and multidrug resistant human tumor cell lines. Intern J Biol Biomed Eng. 2011, 5: 93-101.","journal-title":"Intern J Biol Biomed Eng"},{"key":"316_CR31","doi-asserted-by":"publisher","first-page":"7071","DOI":"10.1074\/jbc.275.10.7071","volume":"275","author":"WL Erdahl","year":"2000","unstructured":"Erdahl WL, Chapman CJ, Taylor RW, Pfeiffer DR: Ionomycin, a carboxylic acid ionophore, transports Pb2+ with high selectivity. J Biol Chem. 2000, 275: 7071-7079. 10.1074\/jbc.275.10.7071.","journal-title":"J Biol Chem"},{"key":"316_CR32","doi-asserted-by":"publisher","first-page":"38111","DOI":"10.1074\/jbc.M205590200","volume":"277","author":"SA Hamidinia","year":"2002","unstructured":"Hamidinia SA, Shimelis OI, Tan B, Erdahl WL, Chapman CJ, Renkes GD, Taylor RW, Pfeiffer DR: Monensin mediates a rapid and selective transport of Pb2+- possible application of monensin for the treatment of Pb2+ intoxication. J Biol Chem. 2002, 277: 38111-38120. 10.1074\/jbc.M205590200.","journal-title":"J Biol Chem"},{"key":"316_CR33","doi-asserted-by":"publisher","first-page":"15956","DOI":"10.1021\/bi048175z","volume":"43","author":"SA Hamidinia","year":"2004","unstructured":"Hamidinia SA, Tan B, Erdahl WL, Chapman CJ, Taylor RW, Pfeiffer DR: The ionophore nigericin transports Pb2+ with high activity and selectivity: a comparison to monensin and ionomycin. Biochemistry. 2004, 43: 15956-15965. 10.1021\/bi048175z.","journal-title":"Biochemistry"},{"key":"316_CR34","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1289\/ehp.8279","volume":"114","author":"SA Hamidinia","year":"2006","unstructured":"Hamidinia SA, Erdahl WL, Chapman CJ, Steinbaugh GE, Taylor RW, Pfeiffer DR: Monensin improves the effectiveness of mesodimercaptosuccinate when used to treat lead intoxication in rats. Environm Health Persp. 2006, 114: 484-493.","journal-title":"Environm Health Persp"},{"key":"316_CR35","doi-asserted-by":"publisher","first-page":"10109","DOI":"10.1016\/S0040-4020(01)96060-0","volume":"47","author":"FG Riddell","year":"1991","unstructured":"Riddell FG, Tompsett SJ: The complete assignment of the 1H and 13C NMR spectra of the alkali metal salts of salinomycin and narasin. Tetrahedron. 1991, 47: 10109-10118. 10.1016\/S0040-4020(01)96060-0.","journal-title":"Tetrahedron"},{"key":"316_CR36","doi-asserted-by":"publisher","first-page":"14989","DOI":"10.1021\/ja075024l","volume":"129","author":"N Matsumori","year":"2007","unstructured":"Matsumori N, Morooka A, Murata M: Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles. J Am Chem Soc. 2007, 129: 14989-14995. 10.1021\/ja075024l.","journal-title":"J Am Chem Soc"},{"key":"316_CR37","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1039\/c0np00002g","volume":"27","author":"N Matsumori","year":"2010","unstructured":"Matsumori N, Murata M: 3D structures of membrane-associated small molecules as determined in isotropic bicelles. Nat Prod Rep. 2010, 27: 1480-1492. 10.1039\/c0np00002g.","journal-title":"Nat Prod Rep"}],"container-title":["Chemistry Central Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-153X-5-52.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/1752-153X-5-52\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-153X-5-52.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T16:23:44Z","timestamp":1630513424000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcchem.biomedcentral.com\/articles\/10.1186\/1752-153X-5-52"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,9]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["316"],"URL":"https:\/\/doi.org\/10.1186\/1752-153x-5-52","relation":{},"ISSN":["1752-153X"],"issn-type":[{"value":"1752-153X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,9]]},"assertion":[{"value":"6 May 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"52"}}