{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T12:47:15Z","timestamp":1648644435627},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,5,3]],"date-time":"2007-05-03T00:00:00Z","timestamp":1178150400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>A non-smoking 77-year old gentleman of Indian origin was admitted with a 4-month history of intermittent night sweats, haemoptysis and 6 kg of weight loss. CT scan of thorax demonstrated a 2.5 cm mass in the right middle lobe with multiple small nodules within the right lung and confirmed the presence of mediastinal and hilar lymph nodes.<\/jats:p>\n          <jats:p>Fibreoptic bronchoscopy demonstrated a distorted right main bronchus, anterior shift of the right upper lobe and occlusion of the right middle lobe bronchus with a black necrotic ulcer. <jats:italic>Mycobacterium tuberculosis<\/jats:italic> was found in the bronchoalveolar lavage and histology demonstrated numerous fungal hyphae with a morphological appearance of zygomycetes within necrotic areas of tissue. Medical management with anti-fungal and anti-mycobacterial treatment was instigated as the patient's pre-existing IHD did not permit surgical intervention. Subsequently CT imaging following completion of therapy demonstrated improvement of the mass and a resolution of the associated nodules. The patient has been followed for 6 months to date and there has been no recurrence of symptoms. Recent bronchoalveolar lavage cultures have been negative for <jats:italic>M. tuberculosis<\/jats:italic> and zygomycetes.<\/jats:p>","DOI":"10.1186\/1752-1947-1-17","type":"journal-article","created":{"date-parts":[[2007,5,3]],"date-time":"2007-05-03T18:25:21Z","timestamp":1178216721000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report"],"prefix":"10.1186","volume":"1","author":[{"given":"Tejal","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian J","family":"Clifton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack A","family":"Kastelik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel G","family":"Peckham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,5,3]]},"reference":[{"key":"17_CR1","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1128\/CMR.13.2.236-301.2000","volume":"13","author":"JA Ribes","year":"2000","unstructured":"Ribes JA, Vanover-Sams CL, Baker DJ: Zygomycetes in human disease. Clincial Microbiology Reviews. 2000, 13: 236-301. 10.1128\/CMR.13.2.236-301.2000.","journal-title":"Clincial Microbiology Reviews"},{"key":"17_CR2","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1097\/00005792-198603000-00004","volume":"65","author":"NA Parfrey","year":"1986","unstructured":"Parfrey NA: Improved diagnosis and prognosis of mucormycosis. A clinicopathologic study of 33 cases. Medicine (Baltimore). 1986, 65: 113-123.","journal-title":"Medicine (Baltimore)"},{"key":"17_CR3","doi-asserted-by":"publisher","first-page":"93","DOI":"10.7326\/0003-4819-93-1-93","volume":"93","author":"RI Lehrer","year":"1980","unstructured":"Lehrer RI, Howard DH: Mucormycosis. Ann Intern Med. 1980, 93: 93-108.","journal-title":"Ann Intern Med"},{"key":"17_CR4","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1001\/archinte.159.12.1301","volume":"159","author":"FY Lee","year":"1999","unstructured":"Lee FY, Mossad SB, Adal KA: Pulmonary mucormycosis: the last 30 years. Arch Intern Med. 1999, 159: 1301-1309. 10.1001\/archinte.159.12.1301.","journal-title":"Arch Intern Med"},{"key":"17_CR5","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1016\/0003-4975(94)90243-7","volume":"57","author":"M Tedder","year":"1994","unstructured":"Tedder M, Spratt JA, Anstadt MP, Hegde SS, Tedder SD, Lowe JE: Pulmonary mucormycosis: results of medical and surgical therapy. Ann Thorac Surg. 1994, 57: 1044-1050.","journal-title":"Ann Thorac Surg"},{"key":"17_CR6","first-page":"572","volume":"87","author":"A Butala","year":"1995","unstructured":"Butala A, Shah B, Cho YT, Schmidt MF: Isolated pulmonary mucormycosis in an apparently normal host: a case report. J Natl Med Assoc. 1995, 87: 572-574.","journal-title":"J Natl Med Assoc"},{"key":"17_CR7","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1136\/thx.35.11.877","volume":"35","author":"T Matsushima","year":"1980","unstructured":"Matsushima T, Soejima R, Nakashima T: Solitary pulmonary nodule caused by phycomycosis in a patient without obvious predisposing factors. Thorax. 1980, 35: 877-878.","journal-title":"Thorax"},{"key":"17_CR8","first-page":"100","volume":"35","author":"H Tojima","year":"1997","unstructured":"Tojima H, Tokudome T, Otsuka T: [Chronic pulmonary mucormycosis that developed in preexisting cavities caused by tuberculosis in a patient with diabetes mellitus and liver cirrhosis]. Nihon Kyobu Shikkan Gakkai Zasshi. 1997, 35: 100-105.","journal-title":"Nihon Kyobu Shikkan Gakkai Zasshi"},{"key":"17_CR9","first-page":"903","volume":"22","author":"R Miyamoto","year":"1981","unstructured":"Miyamoto R, Hongo T, Takehiro A, Igarashi Y, Ueyama T, Harada Y: [A case of acute myelogenous leukemia complicated with pulmonary tuberculosis and pulmonary mucormycosis (author's transl)]. Rinsho Ketsueki. 1981, 22: 903-908.","journal-title":"Rinsho Ketsueki"},{"key":"17_CR10","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.2214\/ajr.168.6.9168721","volume":"168","author":"HP McAdams","year":"1997","unstructured":"McAdams HP, Rosado dC, Strollo DC, Patz EF: Pulmonary mucormycosis: radiologic findings in 32 cases. AJR Am J Roentgenol. 1997, 168: 1541-1548.","journal-title":"AJR Am J Roentgenol"},{"key":"17_CR11","doi-asserted-by":"publisher","first-page":"698","DOI":"10.4065\/74.7.698","volume":"74","author":"DM Collins","year":"1999","unstructured":"Collins DM, Dillard TA, Grathwohl KW, Giacoppe GN, Arnold BF: Bronchial mucormycosis with progressive air trapping. Mayo Clin Proc. 1999, 74: 698-701.","journal-title":"Mayo Clin Proc"},{"key":"17_CR12","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/BF02113443","volume":"14","author":"R Kocak","year":"1995","unstructured":"Kocak R, Tetiker T, Kocak M, Baslamisli F, Zorludemir S, Gonlusen G: Fluconazole in the treatment of three cases of mucormycosis. Eur J Clin Microbiol Infect Dis. 1995, 14: 559-561. 10.1007\/BF02113443.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"17_CR13","doi-asserted-by":"publisher","first-page":"228","DOI":"10.2169\/internalmedicine1962.28.228","volume":"28","author":"H Funada","year":"1989","unstructured":"Funada H, Miyake Y, Kanamori K, Okafuji K, Machi T, Matsuda T: Fluconazole therapy for pulmonary mucormycosis complicating acute leukemia. Jpn J Med. 1989, 28: 228-231.","journal-title":"Jpn J Med"},{"key":"17_CR14","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1093\/jac\/48.4.583","volume":"48","author":"J Mosquera","year":"2001","unstructured":"Mosquera J, Warn PA, Rodriguez-Tudela JL, Denning DW: Treatment of Absidia corymbifera infection in mice with amphotericin B and itraconazole. J Antimicrob Chemother. 2001, 48: 583-586. 10.1093\/jac\/48.4.583.","journal-title":"J Antimicrob Chemother"},{"key":"17_CR15","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1086\/375075","volume":"36","author":"AM Tobon","year":"2003","unstructured":"Tobon AM, Arango M, Fernandez D, Restrepo A: Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy. Clin Infect Dis. 2003, 36: 1488-1491. 10.1086\/375075.","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-1-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-1-17\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-1-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-1-17.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T08:12:12Z","timestamp":1630483932000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-1-17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,3]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["17"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-1-17","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,3]]},"assertion":[{"value":"15 January 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2007","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2007","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"17"}}