{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T21:27:49Z","timestamp":1773091669040,"version":"3.50.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T00:00:00Z","timestamp":1201132800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>Primary pulmonary synovial sarcoma is an extremely rare tumor with only few case reports in the literature.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A healthy 67-year-old woman was admitted for investigation of a pulmonary mass found on a routine X-ray. She had a history of breast cancer diagnosed and treated 13 years previously with left mastectomy followed by adjuvant endocrine therapy. No progression of the disease was reported. Thoracic computer tomography disclosed a soft-tissue mass in the lower lobe of the left lung arising in the vicinity of the pleura. No abnormal lymph nodes were noted. Further work-up for metastases was negative. Subsequently, the lower lobe of the left lung was removed and the diagnosis was a monophasic synovial sarcoma.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The diagnosis of monophasic primary pulmonary synovial sarcoma requires clinical, imaging and immunohistochemical investigation to exclude alternative primary sources. The treatment of choice is excision (lobectomy or pneumonectomy), which in most of cases is helpful for diagnosis. The prognosis is usually poor.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-2-18","type":"journal-article","created":{"date-parts":[[2008,1,25]],"date-time":"2008-01-25T19:18:12Z","timestamp":1201288692000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Primary monophasic synovial sarcoma presenting as a pulmonary mass: a case report"],"prefix":"10.1186","volume":"2","author":[{"given":"Charalampos M.","family":"Mermigkis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antony","family":"Kopanakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Patentalakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vlassis","family":"Polychronopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Patentalakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,1,24]]},"reference":[{"issue":"10","key":"205_CR1","doi-asserted-by":"publisher","first-page":"679","DOI":"10.2169\/internalmedicine.45.1508","volume":"45","author":"C Zamarr\u00f3n","year":"2006","unstructured":"Zamarr\u00f3n C, Abdulkader I, Alvarez UC, Bar\u00f3n FJ, Prim JM, Ledo RL, Forteza J: Primary synovial sarcoma of the lung. Intern Med. 2006, 45 (10): 679-683. 10.2169\/internalmedicine.45.1508.","journal-title":"Intern Med"},{"issue":"3","key":"205_CR2","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/S0169-5002(02)00303-3","volume":"38","author":"B Etienne-Mastroianni","year":"2002","unstructured":"Etienne-Mastroianni B, Falchero L, Chalabreysse L, Loire R, Ranch\u00e8re D, Souquet PJ, Cordier JF: Primary sarcomas of the lung. A clinicopathologic study of 12 cases. Lung Cancer. 2002, 38 (3): 283-289. 10.1016\/S0169-5002(02)00303-3.","journal-title":"Lung Cancer"},{"issue":"2","key":"205_CR3","first-page":"137","volume":"10","author":"O Nappi","year":"1993","unstructured":"Nappi O, Wick MR: Sarcomatoid neoplasms of the respiratory tract. Semin Diagn Pathol. 1993, 10 (2): 137-147.","journal-title":"Semin Diagn Pathol"},{"issue":"1","key":"205_CR4","first-page":"23","volume":"11","author":"O Cakir","year":"2005","unstructured":"Cakir O, Topal U, Bayram AS, Tolunay S: Sarcomas: rare primary malignant tumors of the thorax. Diagn Interv Radiol. 2005, 11 (1): 23-27.","journal-title":"Diagn Interv Radiol"},{"issue":"3","key":"205_CR5","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1148\/radiographics.22.3.g02ma17621","volume":"22","author":"GW Gladish","year":"2002","unstructured":"Gladish GW, Sabloff BM, Munden RF, Truong MT, Erasmus JJ, Chasen MH: Primary thoracic sarcomas. Radiographics. 2002, 22 (3): 621-637.","journal-title":"Radiographics"},{"issue":"1","key":"205_CR6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/107327480501200102","volume":"12","author":"HJ Mankin","year":"2005","unstructured":"Mankin HJ, Hornicek FJ: Diagnosis, classification, and management of soft tissue sarcomas. Cancer Control. 2005, 12 (1): 5-21.","journal-title":"Cancer Control"},{"key":"205_CR7","first-page":"1483","volume-title":"Enzinger and Weiss's soft tissue tumors","author":"SW Weiss","year":"2001","unstructured":"Weiss SW, Goldblum JR: From malignant soft tissue tumors of uncertain type. Enzinger and Weiss's soft tissue tumors. Edited by: Weiss SW, Goldblum JR. 2001, St. Louis: Mosby, 1483-1571. 4","edition":"4"},{"issue":"7","key":"205_CR8","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1016\/j.humpath.2004.02.011","volume":"35","author":"S Okamoto","year":"2004","unstructured":"Okamoto S, Hisaoka M, Daa T, Hatakeyama K, Iwamasa T, Hashimoto H: Primary pulmonary synovial sarcoma: a clinicopathologic, immunohistochemical, and molecular study of 11 cases. Hum Pathol. 2004, 35 (7): 850-856. 10.1016\/j.humpath.2004.02.011.","journal-title":"Hum Pathol"},{"key":"205_CR9","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/cncr.10188","volume":"94","author":"LR Essary","year":"2002","unstructured":"Essary LR, Vargas SO, Fletcher CD: Primary pleuropulmonary synovial sarcoma: reappraisal of a recently described anatomic subset. Cancer. 2002, 94: 459-469. 10.1002\/cncr.10188.","journal-title":"Cancer"},{"issue":"5","key":"205_CR10","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1097\/00000478-200105000-00007","volume":"25","author":"M Miettinen","year":"2001","unstructured":"Miettinen M, Limon J, Niezabitowski A, Lasota J: Calretinin and other mesothelioma markers in synovial sarcoma: analysis of antigenic similarities and differences with malignant mesothelioma. Am J Surg Pathol. 2001, 25 (5): 610-617. 10.1097\/00000478-200105000-00007.","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"205_CR11","first-page":"601","volume":"148","author":"K Nagao","year":"1996","unstructured":"Nagao K, Ito H, Yoshida H: Chromosomal translocation t(X,18) in human synovial sarcomas analyzed by FISH using paraffin-embedded tissue. Am J Pathol. 1996, 148 (2): 601-609.","journal-title":"Am J Pathol"},{"issue":"5","key":"205_CR12","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1093\/jjco\/hyi073","volume":"35","author":"T Hosono","year":"2005","unstructured":"Hosono T, Hironaka M, Kobayashi A, Yamasawa H, Bando M, Ohno S, Sohara Y, Sugiyama Y: Primary pulmonary synovial sarcoma confirmed by molecular detection of SYT-SSX1 fusion gene transcripts: a case report and review of the literature. Jpn J Clin Oncol. 2005, 35 (5): 274-279. 10.1093\/jjco\/hyi073.","journal-title":"Jpn J Clin Oncol"},{"key":"205_CR13","doi-asserted-by":"publisher","first-page":"2700","DOI":"10.1002\/cncr.11840","volume":"98","author":"JM Coindre","year":"2003","unstructured":"Coindre JM, Pelmus M, Hostein I, Lussan C, Bui BN, Guillou L: Should molecular testing be required for diagnosing synovial sarcoma?. Cancer. 2003, 98: 2700-2707. 10.1002\/cncr.11840.","journal-title":"Cancer"},{"issue":"3","key":"205_CR14","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1634\/theoncologist.9-3-339","volume":"9","author":"S Dennison","year":"2004","unstructured":"Dennison S, Weppler E, Giacoppe G: Primary pulmonary synovial sarcoma: a case report and review of current diagnostic and therapeutic standards. Oncologist. 2004, 9 (3): 339-342. 10.1634\/theoncologist.9-3-339.","journal-title":"Oncologist"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-2-18\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T03:14:06Z","timestamp":1630466046000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-2-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,24]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["205"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-2-18","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,24]]},"assertion":[{"value":"19 June 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"18"}}