{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:49:38Z","timestamp":1762505378847},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,9,10]],"date-time":"2008-09-10T00:00:00Z","timestamp":1221004800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1186\/1752-1947-2-300","type":"journal-article","created":{"date-parts":[[2008,9,19]],"date-time":"2008-09-19T18:14:49Z","timestamp":1221848089000},"source":"Crossref","is-referenced-by-count":20,"title":["Fatal hemolytic anemia associated with metformin: A case report"],"prefix":"10.1186","volume":"2","author":[{"given":"Clifford D","family":"Packer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R","family":"Hornick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah A","family":"Augustine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,9,10]]},"reference":[{"key":"487_CR1","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1056\/NEJM199812173392517","volume":"339","author":"K-D Lin","year":"1998","unstructured":"Lin K-D, Lin J-D, Juang J-H: Metformin-induced hemolysis with jaundice. N Engl J Med. 1998, 339: 659-671. 10.1056\/NEJM199812173392517.","journal-title":"N Engl J Med"},{"key":"487_CR2","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1136\/pmj.76.892.125","volume":"76","author":"AS Kashyap","year":"2000","unstructured":"Kashyap AS, Kashyap S: Haemolytic anaemia due to metformin. Postgrad Med J. 2000, 76: 125-126. 10.1136\/pmj.76.892.125.","journal-title":"Postgrad Med J"},{"key":"487_CR3","doi-asserted-by":"publisher","first-page":"956","DOI":"10.2337\/diacare.26.3.956","volume":"26","author":"A Meir","year":"2003","unstructured":"Meir A, Kleinman Y, Rund D, Da'as N: Metformin-induced hemolytic anemia in a patient with glucose-6-phosphate dehydrogenase deficiency. Diabetes Care. 2003, 26: 956-957. 10.2337\/diacare.26.3.956.","journal-title":"Diabetes Care"},{"key":"487_CR4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/clpt.1981.154","volume":"30","author":"CA Naranjo","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ: A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981, 30: 239-245.","journal-title":"Clin Pharmacol Ther"},{"key":"487_CR5","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1081\/JDI-120022557","volume":"25","author":"S Lim","year":"2003","unstructured":"Lim S, Alam MG: Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia. Ren Fail. 2003, 25: 647-651. 10.1081\/JDI-120022557.","journal-title":"Ren Fail"},{"key":"487_CR6","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1097\/00004836-200105000-00030","volume":"32","author":"A Mert","year":"2001","unstructured":"Mert A, Tabak F, Ozturk R, Aktuglu Y, Ozaras R, Kanat M: Acute viral hepatitis with severe hyperbilirubinemia and massive hemolysis in G6PD deficiency. J Clin Gastroenterol. 2001, 32: 461-462. 10.1097\/00004836-200105000-00030.","journal-title":"J Clin Gastroenterol"},{"key":"487_CR7","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1136\/bmj.1.5950.131","volume":"1","author":"TK Chan","year":"1975","unstructured":"Chan TK, Todd D: Hemolysis complicating viral hepatitis in patients with glucose-6-phosphate dehydrogenase deficiency. Br J Med. 1975, 1: 131-133.","journal-title":"Br J Med"},{"key":"487_CR8","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1093\/clinchem\/46.12.2027","volume":"46","author":"DR Dufour","year":"2000","unstructured":"Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB: Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests. Clin Chem. 2000, 46: 2027-2049.","journal-title":"Clin Chem"},{"key":"487_CR9","first-page":"29","volume":"8","author":"HS Kaplan","year":"1985","unstructured":"Kaplan HS, Garratty G: The predictive value of the direct antiglobulin test. Diagnostic Medicine. 1985, 8: 29-33.","journal-title":"Diagnostic Medicine"},{"key":"487_CR10","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1002\/ajh.10062","volume":"69","author":"BC Gehrs","year":"2002","unstructured":"Gehrs BC, Friedberg RC: Autoimmune hemolytic anemia. Am J Hematol. 2002, 69: 258-271. 10.1002\/ajh.10062.","journal-title":"Am J Hematol"},{"key":"487_CR11","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1111\/j.1537-2995.2007.01173.x","volume":"47","author":"ST Johnson","year":"2007","unstructured":"Johnson ST, Fueger JT, Gottschall JL: One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia \u2013 a new paradigm. Transfusion. 2007, 47: 697-702. 10.1111\/j.1537-2995.2007.01173.x.","journal-title":"Transfusion"},{"key":"487_CR12","first-page":"310","volume-title":"Immunohematology: Principles and Practice","author":"ED Quinley","year":"1998","unstructured":"Quinley ED: Mechanisms of drug-induced hemolytic anemia. Immunohematology: Principles and Practice. 1998, Philadelphia, PA: Lippincott Williams & Wilkins, 310-2","edition":"2"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-2-300\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-300.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-300","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-300.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T11:05:43Z","timestamp":1588935943000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-2-300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,10]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["487"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-2-300","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,10]]},"article-number":"300"}}