{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T18:48:01Z","timestamp":1783968481146,"version":"3.55.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>\n              <jats:italic>Capnocytophaga<\/jats:italic> are a genus of bacteria that have been found to be the causative organisms in a range of infections, including serious conditions such as bacteraemia, endocarditis and meningitis. This has been especially true amongst those with serious comorbidities and the immunocompromised populations. Although several species are known to cause human disease, historically, laboratories have often not identified isolates to species level due to the unreliable, laborious techniques needed. With the advent of Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis, identification to species level is now frequently possible and desirable, as it may provide clues as to the source of infection and its treatment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>Here we describe a case of bacteraemia and possible endocarditis in a 64-year-old white British man caused by a newly identified genomospecies of <jats:italic>Capnocytophaga<\/jats:italic> in a patient subsequently diagnosed with metastatic adenocarcinoma of the oesophagus. The source of the bacteraemia was presumed to be from the patient's own oral flora.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Our case further confirms the potential for <jats:italic>Capnocytophaga<\/jats:italic> to cause systemic infections, highlights the availability and need for identification of isolates to species level and re-emphasises the difficulty in diagnosing <jats:italic>Capnocytophaga<\/jats:italic> infections due to their slow growth in the laboratory.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-2-369","type":"journal-article","created":{"date-parts":[[2012,5,10]],"date-time":"2012-05-10T10:41:03Z","timestamp":1336646463000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A patient with bacteraemia and possible endocarditis caused by a recently-discovered genomospecies of Capnocytophaga: Capnocytophaga genomospecies AHN8471: a case report"],"prefix":"10.1186","volume":"2","author":[{"given":"Jonathan M","family":"Mills","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Lofthouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannis A","family":"Karas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,12,4]]},"reference":[{"key":"556_CR1","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1099\/jmm.0.05274-0","volume":"53","author":"J Sandoe","year":"2004","unstructured":"Sandoe J: Capnocytophaga canimorsus endocarditis. J Med Microbiol. 2004, 53: 245-248. 10.1099\/jmm.0.05274-0.","journal-title":"J Med Microbiol"},{"key":"556_CR2","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1046\/j.1469-0691.2003.00538.x","volume":"9","author":"H Bonatti","year":"2003","unstructured":"Bonatti H, Rossboth DW, Nachbaur D, Fille M, Asp\u00f6ck C, Hend I, Hourmont K, White L, Malnick H, Allerberger FJ: A series of Infections due to Capnocytophaga spp. in immunosuppressed and immunocompetent patients. Clin Microbiol Infect. 2003, 9: 280-387. 10.1046\/j.1469-0691.2003.00538.x.","journal-title":"Clin Microbiol Infect"},{"key":"556_CR3","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/BF00144007","volume":"12","author":"C Lion","year":"1996","unstructured":"Lion C, Escande F, Durdin JC: Capnocytophaga canimorsus infections in human: Review of the literature and cases report. 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J Clin Microbiol. 1984, 19: 538-540.","journal-title":"J Clin Microbiol"},{"key":"556_CR8","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1086\/514493","volume":"25","author":"G Weber","year":"1997","unstructured":"Weber G, Abu-Shakra M, Hertzanu Y, Borer A, Sukenik S: Liver abscess caused by Capnocytophaga species. Clin Infect Dis. 1997, 25: 152-153. 10.1086\/514493.","journal-title":"Clin Infect Dis"},{"key":"556_CR9","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1128\/JCM.01815-06","volume":"45","author":"H Wang","year":"2007","unstructured":"Wang H, Chen YC, Teng LJ, Hung CC, Chen ML, Du SH, Pan HJ, Hsueh PR, Chang SC: Brain abscess associated with multidrug-resistant Capnocytophaga ochracea infection. J Clin Microbiol. 2007, 45: 645-647. 10.1128\/JCM.01815-06.","journal-title":"J Clin Microbiol"},{"key":"556_CR10","doi-asserted-by":"crossref","unstructured":"Ciantar M, Newman HN, Wilson M, Spratt DA: Molecular identification of Capnocytophaga spp. via 16S rRNA PCR-restriction fragment length polymorphism analysis. J Clin Microbiol. 43: 1894-1901. 10.1128\/JCM.43.4.1894-1901.2005.","DOI":"10.1128\/JCM.43.4.1894-1901.2005"},{"issue":"Pt 2","key":"556_CR11","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1099\/ijs.0.65373-0","volume":"58","author":"EV Frandsen","year":"2008","unstructured":"Frandsen EV, Poulsen K, K\u00f6n\u00f6nen E, Kilian M: Diversity of Capnocytophaga species in children and description of Capnocytophaga leadbetteri sp. nov. and Capnocytophaga genospecies AHN8471. Int J Syst Evol Microbiol. 2008, 58 (Pt 2): 324-336. 10.1099\/ijs.0.65373-0.","journal-title":"Int J Syst Evol Microbiol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-369.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-2-369\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-369","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-369.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T03:18:06Z","timestamp":1630466286000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-2-369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["556"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-2-369","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"29 February 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"369"}}