{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:35:00Z","timestamp":1761561300581},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>Lemierre's syndrome is septic thrombophlebitis of the internal jugular vein leading to metastatic septic complications following an oropharyngeal infection. It is usually caused by the anaerobe, <jats:italic>Fusobacterium necrophorum<\/jats:italic>. Of late, meticillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> is increasingly being recognised as a cause of community-acquired skin and soft tissue infections. We report a rare case of Lemierre's syndrome caused by community-acquired meticillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> infection.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A previously healthy 16-year-old girl presented with fever of 13 days duration, painful swelling around the right eye and diplopia followed by the appearance of pulmonary infiltrates. Imaging studies confirmed the clinical suspicion of bilateral jugular venous thrombosis with septic pulmonary embolism. Meticillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> was isolated on blood cultures. The hospital course was complicated by massive haemoptysis and pulmonary aspiration necessitating mechanical ventilation. The patient subsequently made a complete recovery.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Lemierre's syndrome, although rare, is a potentially lethal but treatable complication of head and neck sepsis. Early clinical recognition of Lemierre's syndrome and appropriate antibiotic treatment can be life-saving. One should consider the possibility of community-acquired meticillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> infection in patients with suspected Lemierre's syndrome.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-2-374","type":"journal-article","created":{"date-parts":[[2008,12,9]],"date-time":"2008-12-09T07:13:26Z","timestamp":1228806806000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Lemierre's syndrome due to community-acquired meticillin-resistant Staphylococcus aureus infection and presenting with orbital cellulitis: a case report"],"prefix":"10.1186","volume":"2","author":[{"given":"Tamilarasu","family":"Kadhiravan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paramasivan","family":"Piramanayagam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Banga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiva","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surendra K","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,12,8]]},"reference":[{"key":"561_CR1","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1086\/313970","volume":"31","author":"LH Kristensen","year":"2000","unstructured":"Kristensen LH, Prag J: Human necrobacillosis with special emphasis on Lemierre's syndrome. Clin Infect Dis. 2000, 31: 524-532. 10.1086\/313970.","journal-title":"Clin Infect Dis"},{"key":"561_CR2","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1136\/pgmj.2003.014274","volume":"80","author":"T Riordan","year":"2004","unstructured":"Riordan T, Wilson M: Lemierre's syndrome: more than a historical curiosa. Postgrad Med J. 2004, 80: 328-334. 10.1136\/pgmj.2003.014274.","journal-title":"Postgrad Med J"},{"key":"561_CR3","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/S1473-3099(05)70112-2","volume":"5","author":"N Zetola","year":"2005","unstructured":"Zetola N, Francis JS, Nuermberger EL, Bishai WR: Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis. 2005, 5: 275-286. 10.1016\/S1473-3099(05)70112-2.","journal-title":"Lancet Infect Dis"},{"key":"561_CR4","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1097\/00005792-200211000-00006","volume":"81","author":"JA Chirinos","year":"2002","unstructured":"Chirinos JA, Lichtstein DM, Garcia J, Tamariz LJ: The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine (Baltimore). 2002, 81: 458-465. 10.1097\/00005792-200211000-00006.","journal-title":"Medicine (Baltimore)"},{"key":"561_CR5","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1046\/j.1440-1754.2002.00784.x","volume":"38","author":"SM Fong","year":"2002","unstructured":"Fong SM, Watson M: Lemierre syndrome due to non-multiresistant methicillin-resistant Staphylococcus aureus. J Paediatr Child Health. 2002, 38: 305-307. 10.1046\/j.1440-1754.2002.00784.x.","journal-title":"J Paediatr Child Health"},{"key":"561_CR6","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s11239-006-9050-3","volume":"23","author":"C Boga","year":"2007","unstructured":"Boga C, Ozdogu H, Diri B, Oguzkurt L, Asma S, Yeral M: Lemierre syndrome variant: Staphylococcus aureus associated with thrombosis of both the right internal jugular vein and the splenic vein after the exploration of a river cave. J Thromb Thrombolysis. 2007, 23: 151-154. 10.1007\/s11239-006-9050-3.","journal-title":"J Thromb Thrombolysis"},{"key":"561_CR7","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1056\/NEJMoa055356","volume":"355","author":"GJ Moran","year":"2006","unstructured":"Moran GJ, Krishnadasan A, Gorwitz RJ, Fosheim GE, McDougal LK, Carey RB, Talan DA, for the EMERGEncy ID Net Study Group: Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med. 2006, 355: 666-674. 10.1056\/NEJMoa055356.","journal-title":"N Engl J Med"},{"key":"561_CR8","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/j.1365-4632.2004.02138.x","volume":"43","author":"U Nagaraju","year":"2004","unstructured":"Nagaraju U, Bhat G, Kuruvila M, Pai GS, Jayalakshmi , Babu RP: Methicillin-resistant Staphylococcus aureus in community-acquired pyoderma. Int J Dermatol. 2004, 43: 412-414. 10.1111\/j.1365-4632.2004.02138.x.","journal-title":"Int J Dermatol"},{"key":"561_CR9","doi-asserted-by":"publisher","first-page":"126","DOI":"10.4103\/0378-6323.25637","volume":"72","author":"R Patil","year":"2006","unstructured":"Patil R, Baveja S, Nataraj G, Khopkar U: Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in community-acquired primary pyoderma. Indian J Dermatol Venereol Leprol. 2006, 72: 126-128.","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"561_CR10","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1542\/peds.2005-2009","volume":"117","author":"BE Gonzalez","year":"2006","unstructured":"Gonzalez BE, Teruya J, Mahoney DH, Hulten KG, Edwards R, Lamberth LB, Hammerman WA, Mason EO, Kaplan SL: Venous thrombosis associated with staphylococcal osteomyelitis in children. Pediatrics. 2006, 117: 1673-1679. 10.1542\/peds.2005-2009.","journal-title":"Pediatrics"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-374.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-2-374\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-2-374.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T03:17:09Z","timestamp":1630466229000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-2-374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["561"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-2-374","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"4 February 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"374"}}