{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T18:19:12Z","timestamp":1735582752668},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,6,24]],"date-time":"2010-06-24T00:00:00Z","timestamp":1277337600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>The medical management of secondary hyperparathyroidism in patients with end-stage renal disease involves a combination of dietary restrictions, phosphate binders, active vitamin D analogs, and calcimimetics.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>We report the case of a 36-year-old Hispanic dialysis patient, originally from Cuba and now residing in the USA, who developed severe bone pain and muscle twitching after starting low dose cinacalcet, despite normal pre-dialysis ionized calcium and elevated parathyroid hormone. The clinical symptoms correlated with increased symmetrical uptake on bone scan that resolved rapidly upon discontinuation of cinacalcet.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Cinacalcet may induce severe bone pain and a unique bone scan uptake pattern in hemodialysis patients.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-4-191","type":"journal-article","created":{"date-parts":[[2010,6,25]],"date-time":"2010-06-25T06:13:54Z","timestamp":1277446434000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Reversible bone pain and symmetric bone scan uptake in a dialysis patient treated with cinacalcet: a case report"],"prefix":"10.1186","volume":"4","author":[{"given":"Oliver","family":"Lenz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhea","family":"Sancassani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Bottino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Fornoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,6,24]]},"reference":[{"key":"1148_CR1","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1681\/ASN.2007121320","volume":"19","author":"C Valle","year":"2008","unstructured":"Valle C, Rodriguez M, Santamaria R, Almaden Y, Rodriguez ME, Canadillas S, Martin-Malo A, Aljama P: Cinacalcet reduces the set point of the PTH-calcium curve. J Am Soc Nephrol. 2008, 19: 2430-2436. 10.1681\/ASN.2007121320.","journal-title":"J Am Soc Nephrol"},{"key":"1148_CR2","doi-asserted-by":"publisher","first-page":"1718","DOI":"10.2215\/CJN.01040308","volume":"3","author":"S Fishbane","year":"2008","unstructured":"Fishbane S, Shapiro WB, Corry DB, Vicks SL, Roppolo M, Rappaport K, Ling X, Goodman WG, Turner S, Charytan C: Cinacalcet HCl and concurrent low-dose vitamin D improves treatment of secondary hyperparathyroidism in dialysis patients compared with vitamin D alone: the ACHIEVE study results. Clin J Am Soc Nephrol. 2008, 3: 1718-1725. 10.2215\/CJN.01040308.","journal-title":"Clin J Am Soc Nephrol"},{"key":"1148_CR3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1053\/j.ajkd.2008.09.021","volume":"53","author":"M Chonchol","year":"2009","unstructured":"Chonchol M, Locatelli F, Abboud HE, Charytan C, de Francisco AL, Jolly S, Kaplan M, Roger SD, Sarkar S, Albizem MB, Mix TC, Kubo Y, Block GA: A randomized, double-blind, placebo-controlled study to assess the efficacy and safety of cinacalcet HCl in participants with CKD not receiving dialysis. Am J Kidney Dis. 2009, 53: 197-207. 10.1053\/j.ajkd.2008.09.021.","journal-title":"Am J Kidney Dis"},{"key":"1148_CR4","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1525-139X.2007.00248.x","volume":"20","author":"ES Lazar","year":"2007","unstructured":"Lazar ES, Stankus N: Cinacalcet-induced hungry bone syndrome. Semin Dial. 2007, 20: 83-85. 10.1111\/j.1525-139X.2007.00248.x.","journal-title":"Semin Dial"},{"key":"1148_CR5","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1097\/MNM.0b013e3281744440","volume":"28","author":"O Buckley","year":"2007","unstructured":"Buckley O, O'Keeffe S, Geoghegan T, Lyburn ID, Munk PL, Worsley D, Torreggiani WC: 99 mTc bone scintigraphy superscans: a review. Nucl Med Commun. 2007, 28: 521-527. 10.1097\/MNM.0b013e3281744440.","journal-title":"Nucl Med Commun"},{"key":"1148_CR6","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s00774-008-0843-7","volume":"26","author":"T Yamaguchi","year":"2008","unstructured":"Yamaguchi T: The calcium-sensing receptor in bone. J Bone Miner Metab. 2008, 26: 301-311. 10.1007\/s00774-008-0843-7.","journal-title":"J Bone Miner Metab"},{"key":"1148_CR7","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1038\/sj.jid.5700633","volume":"127","author":"CL Tu","year":"2007","unstructured":"Tu CL, Chang W, Bikle DD: The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol. 2007, 127: 1074-1083. 10.1038\/sj.jid.5700633.","journal-title":"J Invest Dermatol"},{"key":"1148_CR8","doi-asserted-by":"publisher","first-page":"3156","DOI":"10.1210\/en.2007-0147","volume":"148","author":"MM Dvorak","year":"2007","unstructured":"Dvorak MM, Chen TH, Orwoll B, Garvey C, Chang W, Bikle DD, Shoback DM: Constitutive activity of the osteoblast Ca2+-sensing receptor promotes loss of cancellous bone. 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Nephrol Dial Transplant. 2005, 20: 1232-1237. 10.1093\/ndt\/gfh829.","journal-title":"Nephrol Dial Transplant"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-4-191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-4-191\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-4-191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-4-191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T05:49:47Z","timestamp":1630475387000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-4-191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,24]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1148"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-4-191","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,24]]},"assertion":[{"value":"21 October 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"191"}}