{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:22:26Z","timestamp":1787019746884,"version":"build-2736575974"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,3,30]],"date-time":"2011-03-30T00:00:00Z","timestamp":1301443200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred treatment is usually pharmaceutical, but surgery may be required for complicated cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      We report two cases of primary intestinal tuberculosis where the initial diagnosis was wrong, with colonic cancer suggested in the first case and a Crohn's disease complication in the second. Both of our patients were Caucasians of Greek nationality. In the first case (a 60-year-old man), a right hemicolectomy was performed. In the second case (a 26-year-old man), excision was impossible due to the local conditions and peritoneal implantations. Histopathology revealed an inflammatory mass of tuberculous origin in the first case. In the second, cell culture and polymerase chain reaction tests revealed\n                      <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                      . Both patients were given anti-tuberculosis therapy and their post-operative follow-up was uneventful.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Gastrointestinal tuberculosis still appears sporadically and should be considered in the differential diagnosis along with other conditions of the bowel. The use of immunosuppressants and new pharmaceutical agents can change the prevalence of tuberculosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/1752-1947-5-128","type":"journal-article","created":{"date-parts":[[2011,4,5]],"date-time":"2011-04-05T14:19:52Z","timestamp":1302013192000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cecal obstruction due to primary intestinal tuberculosis: a case series"],"prefix":"10.1186","volume":"5","author":[{"given":"Antonis","family":"Michalopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilis N","family":"Papadopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Panidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodossis S","family":"Papavramidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios","family":"Chiotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Basdanis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,3,30]]},"reference":[{"key":"1490_CR1","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1097\/MEG.0b013e328012122b","volume":"19","author":"V Sibartie","year":"2007","unstructured":"Sibartie V, Kirwan WO, O'Mahony S, Stack W, Shanahan F: Tuberculosis mimicking Crohn's disease: lessons relearned in a new era. Eur J Gastroenterol Hepatol. 2007, 19: 347-349. 10.1097\/MEG.0b013e328012122b.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"1490_CR2","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1128\/JCM.44.5.1884-1886.2006","volume":"44","author":"R Balamurugan","year":"2006","unstructured":"Balamurugan R, Venkataraman S, John KR, Ramakrishna BS: PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis. J Clin Microbiol. 2006, 44: 1884-1886. 10.1128\/JCM.44.5.1884-1886.2006.","journal-title":"J Clin Microbiol"},{"key":"1490_CR3","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1471-230X-2-10","volume":"2","author":"C Chatzicostas","year":"2002","unstructured":"Chatzicostas C, Koutroubakis IE, Tzardi M, Roussomoustakaki M, Prassopoulos P, Kouroumalis EA: Colonic tuberculosis mimicking Crohn's disease: case report. BMC Gastroenterol. 2002, 2: 10-10.1186\/1471-230X-2-10.","journal-title":"BMC Gastroenterol"},{"key":"1490_CR4","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1111\/j.1365-2036.2007.03332.x","volume":"25","author":"D Epstein","year":"2007","unstructured":"Epstein D, Watermeyer G, Kirsch R: The diagnosis and management of Crohn's disease in populations with high-risk rates for tuberculosis. Aliment Pharmacol Ther. 2007, 25: 1373-1388. 10.1111\/j.1365-2036.2007.03332.x.","journal-title":"Aliment Pharmacol Ther"},{"key":"1490_CR5","first-page":"565","volume":"91","author":"V Singh","year":"1996","unstructured":"Singh V, Kumar P, Kamal J, Prakash V, Vaiphei K, Singh K: Clinicocolonoscopic profile of colonic tuberculosis. Am J Gastroenterol. 1996, 91: 565-568.","journal-title":"Am J Gastroenterol"},{"key":"1490_CR6","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1097\/QCO.0b013e3283306712","volume":"22","author":"HD Donoghue","year":"2009","unstructured":"Donoghue HD, Holton J: Intestinal tuberculosis. Curr Opin Infect Dis. 2009, 22: 490-496. 10.1097\/QCO.0b013e3283306712.","journal-title":"Curr Opin Infect Dis"},{"key":"1490_CR7","first-page":"2248","volume":"89","author":"BS Anand","year":"1994","unstructured":"Anand BS, Schneider FE, El-Zaatari FA, Shawar RM, Clarridge JE, Graham DY: Diagnosis of intestinal tuberculosis by polymerase chain reaction on endoscopic biopsy specimens. Am J Gastroenterol. 1994, 89: 2248-2249.","journal-title":"Am J Gastroenterol"},{"key":"1490_CR8","first-page":"989","volume":"88","author":"JB Marschall","year":"1993","unstructured":"Marschall JB: Tuberculosis of the gastrointestinal tract and the peritoneum. Am J Gastroenterology. 1993, 88: 989-999.","journal-title":"Am J Gastroenterology"},{"key":"1490_CR9","first-page":"569","volume":"56","author":"OE Klimach","year":"1985","unstructured":"Klimach OE, Ormerod LP: Gastrointestinal tuberculosis: a retrospective review of 109 cases in a district general hospital. Q J Med. 1985, 56: 569-578.","journal-title":"Q J Med"},{"key":"1490_CR10","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1001\/archinte.1980.00330160066028","volume":"140","author":"S Sherman","year":"1980","unstructured":"Sherman S, Rohwedder JJ, Ravikrishann KP, Weg JG: Tuberculous enteritis and peritonitis. Report of 36 general hospital cases. Arch Intern Med. 1980, 140: 506-508. 10.1001\/archinte.140.4.506.","journal-title":"Arch Intern Med"},{"key":"1490_CR11","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1093\/infdis\/158.4.687","volume":"158","author":"A Jakubowski","year":"1988","unstructured":"Jakubowski A, Elwood RK, Enarson DA: Clinical features of abdominal tuberculosis. J Infect Dis. 1988, 158: 687-692. 10.1093\/infdis\/158.4.687.","journal-title":"J Infect Dis"},{"key":"1490_CR12","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1136\/gut.33.3.347","volume":"33","author":"S Shah","year":"1992","unstructured":"Shah S, Thomas V, Mathan M, Chacko A, Chandy G, Ramakrishna BS, Rolston DD: Colonoscopic study of 50 patients with colonic tuberculosis. Gut. 1992, 33: 347-351. 10.1136\/gut.33.3.347.","journal-title":"Gut"},{"key":"1490_CR13","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1097\/00004836-199504000-00013","volume":"20","author":"MA al Karawi","year":"1995","unstructured":"al Karawi MA, Mohamed AE, Yasawy MI, Graham DY, Shariq S, Ahmed AM, al Jumah A, Ghandour Z: Protean manifestations of gastrointestinal tuberculosis. Report of 130 patients. J Clin Gastroenterol. 1995, 20: 225-232. 10.1097\/00004836-199504000-00013.","journal-title":"J Clin Gastroenterol"},{"key":"1490_CR14","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/S0016-5107(85)71995-5","volume":"31","author":"DK Bhargava","year":"1985","unstructured":"Bhargava DK, Tandon HD, Chawla TC, Tandon BN, Kapur BM: Diagnosis of ileocecal and colonic tuberculosis by colonoscopy. Gastrointest Endosc. 1985, 31: 68-70. 10.1016\/S0016-5107(85)71995-5.","journal-title":"Gastrointest Endosc"},{"key":"1490_CR15","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1046\/j.1440-1746.1999.01940.x","volume":"14","author":"SP Misra","year":"1999","unstructured":"Misra SP, Misra V, Dwivedi M, Gupta SC: Colonic tuberculosis: clinical features, endoscopic appearance and management. J Gastroenterol Hepatol. 1999, 14: 723-729. 10.1046\/j.1440-1746.1999.01940.x.","journal-title":"J Gastroenterol Hepatol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-5-128\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T09:42:21Z","timestamp":1630489341000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-5-128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,30]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["1490"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-5-128","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,30]]},"assertion":[{"value":"9 June 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"128"}}