{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:59:39Z","timestamp":1754485179036},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,5,26]],"date-time":"2011-05-26T00:00:00Z","timestamp":1306368000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>Central serous chorioretinopathy is characterized by serous neurosensory detachment of the macula and it usually resolves spontaneously with good visual prognosis. In some patients, however, the serous retinal detachment might be very extensive and can result in bullous exudative retinal detachment. We evaluated the use of half-dose verteporfin photodynamic therapy for the treatment of bullous retinal detachment in idiopathic central serous chorioretinopathy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>We report the case of a 51-year-old Chinese man who presented with blurred vision in his right eye and superior visual field defect due to bullous variant of central serous chorioretinopathy. No improvement in vision and retinal detachment was noted after three months of observation and a short course of oral acetazolamide. He was then treated with half-dose verteporfin photodynamic therapy and his visual acuity improved from 20\/70 to 20\/25 within one month of treatment. Three months after photodynamic therapy, there was complete resolution of sub-retinal fluid and bullous retinal detachment. No recurrence of central serous chorioretinopathy was noted in three years of follow-up.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>We report the beneficial effect of photodynamic therapy with half-dose verteporfin as a treatment option for bullous retinal detachment caused by central serous chorioretinopathy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-5-208","type":"journal-article","created":{"date-parts":[[2011,5,26]],"date-time":"2011-05-26T18:17:45Z","timestamp":1306433865000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Half-dose verteporfin photodynamic therapy for bullous variant of central serous chorioretinopathy: a case report"],"prefix":"10.1186","volume":"5","author":[{"given":"Winnie WK","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenith HY","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy YY","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,5,26]]},"reference":[{"issue":"1","key":"1569_CR1","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/00006982-200202000-00005","volume":"22","author":"S Otsuka","year":"2002","unstructured":"Otsuka S, Ohba N, Nakao K: A long-term follow-up study of severe variant of central serous chorioretinopathy. Retina. 2002, 22 (1): 25-32. 10.1097\/00006982-200202000-00005.","journal-title":"Retina"},{"issue":"3","key":"1569_CR2","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/00006982-200306000-00002","volume":"23","author":"LA Yannuzzi","year":"2003","unstructured":"Yannuzzi LA, Slakter JS, Gross NE, Spaide RF, Costa DL, Huang SJ, Klancnik JM, Aisman A: Indocyanine green angiography-guided photodynamic therapy for treatment of chronic central serous chorioretinopathy: a pilot study. Retina. 2003, 23 (3): 288-298. 10.1097\/00006982-200306000-00002.","journal-title":"Retina"},{"issue":"7","key":"1569_CR3","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1136\/bjo.2006.090282","volume":"90","author":"TY Lai","year":"2006","unstructured":"Lai TY, Chan WM, Li H, Lai RY, Liu DT, Lam DS: Safety enhanced photodynamic therapy with half-dose verteporfin for chronic central serous chorioretinopathy: a short term pilot study. Br J Ophthalmol. 2006, 90 (7): 869-874. 10.1136\/bjo.2006.090282.","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"1569_CR4","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1097\/IAE.0b013e3181e378f2","volume":"31","author":"JY Shin","year":"2011","unstructured":"Shin JY, Woo SJ, Yu HG, Park KH: Comparison of efficacy and safety between half-fluence and full-fluence photodynamic therapy for chronic central serous chorioretinopathy. Retina. 2011, 31 (1): 119-126. 10.1097\/IAE.0b013e3181e378f2.","journal-title":"Retina"},{"issue":"10","key":"1569_CR5","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1016\/j.ophtha.2008.04.014","volume":"115","author":"WM Chan","year":"2008","unstructured":"Chan WM, Lai TY, Lai RY, Liu DT, Lam DS: Half-dose verteporfin photodynamic therapy for acute central serous chorioretinopathy: one-year results of a randomized controlled trial. Ophthalmology. 2008, 115 (10): 1756-1765. 10.1016\/j.ophtha.2008.04.014.","journal-title":"Ophthalmology"},{"issue":"8","key":"1569_CR6","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1097\/IAE.0b013e3181a6c028","volume":"29","author":"MW Zhao","year":"2009","unstructured":"Zhao MW, Zhou P, Xiao HX, Lv YS, Li CA, Liu GD, Li XX: Photodynamic therapy for acute central serous chorioretinopathy: the safe effective lowest dose of verteporfin. Retina. 2009, 29 (8): 1155-1161. 10.1097\/IAE.0b013e3181a6c028.","journal-title":"Retina"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-208.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-5-208\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-5-208.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T08:23:29Z","timestamp":1630484609000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-5-208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,26]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["1569"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-5-208","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,26]]},"assertion":[{"value":"20 October 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"208"}}