{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:31:15Z","timestamp":1756463475476},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,8,23]],"date-time":"2011-08-23T00:00:00Z","timestamp":1314057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>Necrotizing sialometaplasia is a benign, self-limiting and rare inflammatory disease which, on clinical and histological examination, mimics malignant neoplasms.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case report<\/jats:title>\n            <jats:p>We report the case of a healthy 25-year-old Caucasian woman with a three-week history of a painless lump on her hard palate. Oral examination revealed a nodule consisting of two lobules on the right side that measured 2.5 cm. Her mucosa was normal in color and a fluctuant area was detected in the posterior region upon palpation. Our patient was submitted to incisional biopsy and histopathological examination. The histological diagnosis was necrotizing sialometaplasia. The lesion had healed spontaneously after 30 days, with observed signs of involution of the nodule.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Histopathological examination is necessary for the diagnosis of necrotizing sialometaplasia because the clinical features of this condition can mimic other diseases, particularly malignant neoplasms.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1752-1947-5-406","type":"journal-article","created":{"date-parts":[[2011,8,23]],"date-time":"2011-08-23T20:37:15Z","timestamp":1314131835000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Necrotizing sialometaplasia as a cause of a non-ulcerated nodule in the hard palate: a case report"],"prefix":"10.1186","volume":"5","author":[{"given":"M\u00f4nica Ghislaine","family":"Oliveira Alves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e1rcio","family":"Kitakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin Rodarte","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Antonio","family":"Guimar\u00e3es Cabral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janete Dias","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,8,23]]},"reference":[{"key":"1775_CR1","first-page":"199","volume":"57","author":"M Fava","year":"2008","unstructured":"Fava M, Cherubini K, Yurgel L, Salum F, Figueiredo MA: Necrotizing sialometaplasia of the palate in a cocaine-using patient. A case report. Minerva Stomatol. 2008, 57: 199-202.","journal-title":"Minerva Stomatol"},{"key":"1775_CR2","first-page":"1087","volume":"127","author":"TA Imbery","year":"1996","unstructured":"Imbery TA, Edwards PA: Necrotising sialometaplasia: literature review and case reports. JADA. 1996, 127: 1087-1092.","journal-title":"JADA"},{"key":"1775_CR3","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/sj.bdj.4810892","volume":"196","author":"PV Keogh","year":"2004","unstructured":"Keogh PV, O'Regan E, Toner M, Flint S: Necrotizing sialometaplasia: an unusual bilateral presentation associated with antecedent anaesthesia and lack of response to intralesional steroids. Case report and review of the literature. Br Dent J. 2004, 196: 79-81. 10.1038\/sj.bdj.4810892.","journal-title":"Br Dent J"},{"key":"1775_CR4","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1111\/j.1365-2559.2007.02762.x","volume":"51","author":"H Rizkalla","year":"2007","unstructured":"Rizkalla H, Toner M: Necrotizing sialometaplasia versus invasive carcinoma of the head and neck: the use of myoepithelial markers and keratin subtypes as an adjunct to diagnosis. Histopathology. 2007, 51: 184-189. 10.1111\/j.1365-2559.2007.02762.x.","journal-title":"Histopathology"},{"key":"1775_CR5","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1046\/j.1365-2559.2002.1179a.x","volume":"40","author":"D Sandmeier","year":"2002","unstructured":"Sandmeier D, Bouzourene H: Necrotizing sialometaplasia: a potential diagnostic pitfall. 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