{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:43:16Z","timestamp":1787766196758,"version":"build-2784847793"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T00:00:00Z","timestamp":1378857600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1186\/1752-1947-7-224","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T16:21:45Z","timestamp":1378916505000},"source":"Crossref","is-referenced-by-count":3,"title":["The emergence of non-secretory multiple myeloma during the non-cytotoxic treatment of essential thrombocythemia: a case report"],"prefix":"10.1186","volume":"7","author":[{"given":"Danijela","family":"Lekovi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjana","family":"Goti\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivera","family":"Mitrovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milica","family":"Radojkovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Bila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Dencic-Fekete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Kraguljac-Kurtovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Peruni\u010di\u0107-Jovanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladan","family":"\u010coki\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,9,11]]},"reference":[{"key":"2619_CR1","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.bcmd.2012.06.004","volume":"49","author":"S Malak","year":"2012","unstructured":"Malak S, Labopin M, Saint-Martin C, Bellanne-Chantelot C, Najman A: The French Group of Familial Myeloproliferative Disorders. Long term follow up of 93 families with myeloproliferative neoplasms: life expectancy and implications of JAK2V617F in the occurrence of complications. Blood Cells Mol Dis. 2012, 49: 170-176. 10.1016\/j.bcmd.2012.06.004.","journal-title":"Blood Cells Mol Dis"},{"key":"2619_CR2","doi-asserted-by":"publisher","first-page":"2410","DOI":"10.1200\/JCO.2011.34.7542","volume":"29","author":"M Bj\u00f6rkholm","year":"2011","unstructured":"Bj\u00f6rkholm M, Derolf AR, Hultcrantz M, Kristinsson SY, Ekstrand C, Goldin LR, Andreasson B, Birgegard G, Linder O, Malm C, Marker\u04d3rn B, Nisson L, Samuelsson J, Granath F, Landgren O: Treatment-related risk factors for transformation to acute myeloid leukemia and myelodysplastic syndromes in myeloproliferative neoplasms. J Clin Oncol. 2011, 29: 2410-2415. 10.1200\/JCO.2011.34.7542.","journal-title":"J Clin Oncol"},{"key":"2619_CR3","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1179\/102453308X316022","volume":"13","author":"F Radaelli","year":"2008","unstructured":"Radaelli F, Onida F, Rossi FG, Zilioli VR, Colombi M, Usardi P, Calori R, Zanella A: Second malignancies in essential thrombocythemia (ET): a retrospective analysis of 331 patients with long-term follow-up from a single institution. Hematology. 2008, 13: 195-202. 10.1179\/102453308X316022.","journal-title":"Hematology"},{"key":"2619_CR4","first-page":"ECR09","volume":"88","author":"NS Majhail","year":"2003","unstructured":"Majhail NS, Lichtin AE: Rare coexistence of multiple myeloma with essential thrombocythemia: report of two cases. Haematologica. 2003, 88: ECR09-","journal-title":"Haematologica"},{"key":"2619_CR5","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1159\/000187645","volume":"120","author":"J Kuroda","year":"2008","unstructured":"Kuroda J, Matsumoto Y, Tanaka R, Kurita K, Kobayashi T, Shimizu D, Kimura S, Ashihara E, Horiike S, Shimazaki C, Taniwaki M: JAK2V617F-positive essential thrombocythemia and multiple myeloma with IGH\/CCND1 gene translocation coexist, but originate from separate clones. Acta Haematol. 2008, 120: 177-181. 10.1159\/000187645.","journal-title":"Acta Haematol"},{"key":"2619_CR6","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.clml.2011.04.001","volume":"11","author":"AE Eskazan","year":"2011","unstructured":"Eskazan AE, Ongoren S, Ar MC, Soysal T, Ferhanoglu B, Aki H, Aydin Y: Essential thrombocythemia and multiple myeloma: two diseases in one patient. Clin Lymphoma Myeloma Leuk. 2011, 11: 442-445. 10.1016\/j.clml.2011.04.001.","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"2619_CR7","first-page":"83","volume":"102","author":"E Sabattini","year":"2010","unstructured":"Sabattini E, Bacci F, Sagramoso C, Pileri SA: WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview. Pathologica. 2010, 102: 83-87.","journal-title":"Pathologica"},{"key":"2619_CR8","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1182\/blood-2004-02-0477","volume":"104","author":"D Coriu","year":"2004","unstructured":"Coriu D, Weaver K, Schell M, Eulitz M, Murphy CL, Weiss DT, Solomon A: A molecular basis for nonsecretory myeloma. Blood. 2004, 104: 829-831. 10.1182\/blood-2004-02-0477.","journal-title":"Blood"},{"key":"2619_CR9","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1309\/74R4TB90BUWH27JX","volume":"121","author":"P Lin","year":"2004","unstructured":"Lin P, Owens R, Tricot G, Wilson CS: Flow cytometric immunophenotypic analyses of 306 cases of multiple myeloma. Am J Pathol. 2004, 121: 482-488.","journal-title":"Am J Pathol"},{"key":"2619_CR10","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1080\/10428190310001615710","volume":"45","author":"A Candoni","year":"2004","unstructured":"Candoni A, Tiribelli M, Fanin R: Plasma cell leukemia occurring in a patient with thrombocythemia treated with hydroxyurea and busulphan. Leuk Lymphoma. 2004, 45: 821-824. 10.1080\/10428190310001615710.","journal-title":"Leuk Lymphoma"},{"key":"2619_CR11","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1046\/j.1365-2141.2000.02188.x","volume":"110","author":"G Finazzi","year":"2000","unstructured":"Finazzi G, Ruggeri M, Rodeghiero F, Barbui T: Second malignancies in patients with Essential Thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial. Br J Haematol. 2000, 110: 577-583. 10.1046\/j.1365-2141.2000.02188.x.","journal-title":"Br J Haematol"},{"key":"2619_CR12","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1002\/cncr.20646","volume":"101","author":"M Steurer","year":"2004","unstructured":"Steurer M, Gastl G, Jedrzejczak WW, Pytlik R, Lin W, Schl\u00f6gl E, Gisslinger H: Anagrelide for thrombocytosis in myeloproliferative disorders. Cancer. 2004, 101: 2239-2246. 10.1002\/cncr.20646.","journal-title":"Cancer"},{"key":"2619_CR13","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.leukres.2004.10.002","volume":"29","author":"SM Fruchtman","year":"2005","unstructured":"Fruchtman SM, Petitt RM, Gilbert HS, Fiddler G, Lyne A, Anagrelide Study Group: Anagrelide: analysis of long-term efficacy, safety and leukemogenic potential in myeloproliferative disorders. Leuk Res. 2005, 29: 481-491. 10.1016\/j.leukres.2004.10.002.","journal-title":"Leuk Res"},{"key":"2619_CR14","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1182\/blood-2012-07-443770","volume":"121","author":"H Gisslinger","year":"2013","unstructured":"Gisslinger H, Gotic M, Holowiecki J, Penka M, Thiele J, Kvasnicka HM, Kralovics R, Petrides PE, ANAHYDRET Study Group: Anagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial. Blood. 2013, 121: 1720-1728. 10.1182\/blood-2012-07-443770.","journal-title":"Blood"},{"key":"2619_CR15","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.3109\/10428194.2010.500435","volume":"51","author":"J Treli\u0144ski","year":"2010","unstructured":"Treli\u0144ski J, Wierzbowska A, Krawczy\u0144ska A, Sakowicz A, Pietrucha T, Smolewski P, Robak T, Chojnowski K: Plasma levels of angiogenic factors and circulating endothelial cells in essential thrombocythemia: correlation with cytoreductive therapy and JAK2-V617F mutational status. Leuk Lymphoma. 2010, 51: 1727-1733.","journal-title":"Leuk Lymphoma"},{"key":"2619_CR16","first-page":"1130","volume":"88","author":"J Thiele","year":"2003","unstructured":"Thiele J, Kvasnicka HM, Fuchs N, Brunnbauer K, Volkwein N, Schmitt-Graeff A: Anagrelide-induced bone marrow changes during therapy of chronic myeloproliferative disorders with thrombocytosis. An immunohistochemical and morphometric study of sequential trephine biopsies. Haematologica. 2003, 88: 1130-1138.","journal-title":"Haematologica"},{"key":"2619_CR17","first-page":"2831","volume":"30","author":"A Giatromanolaki","year":"2010","unstructured":"Giatromanolaki A, Bai M, Margaritis D, Bourantas KL, Koukourakis MI, Sivridis E, Gatter KC: Hypoxia and activated VEGF\/receptor pathway in multiple myeloma. Anticancer Res. 2010, 30: 2831-2836.","journal-title":"Anticancer Res"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1752-1947-7-224\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-7-224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-7-224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1752-1947-7-224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T20:50:48Z","timestamp":1715979048000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-7-224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,11]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["2619"],"URL":"https:\/\/doi.org\/10.1186\/1752-1947-7-224","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,11]]},"article-number":"224"}}