{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:34:09Z","timestamp":1789475649046,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1756-0500-5-689","type":"journal-article","created":{"date-parts":[[2012,12,20]],"date-time":"2012-12-20T23:14:52Z","timestamp":1356045292000},"source":"Crossref","is-referenced-by-count":10,"title":["A rare association of localized scleroderma type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis. Case report"],"prefix":"10.1186","volume":"5","author":[{"given":"Fabio","family":"Bonilla-Abad\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Mu\u00f1oz-Buitr\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos D","family":"Ochoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Carrascal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A","family":"Ca\u00f1as","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,12,20]]},"reference":[{"key":"1930_CR1","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1097\/01.bor.0000245727.40630.c3","volume":"18","author":"RM Laxer","year":"2006","unstructured":"Laxer RM, Zulian F: Localized scleroderma. Curr Opin Rheumatol. 2006, 18: 606-613. 10.1097\/01.bor.0000245727.40630.c3.","journal-title":"Curr Opin Rheumatol"},{"key":"1930_CR2","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1001\/archdermatol.2009.79","volume":"145","author":"JJ Leitenberger","year":"2009","unstructured":"Leitenberger JJ, Cayce RL, Haley RW, Adams-Huet B, Bergstresser PR, Jacobe HT: Distinct autoimmune syndromes in morphea: a review of 245 adult and pediatric cases. Arch Dermatol. 2009, 145: 545-550. 10.1001\/archdermatol.2009.79.","journal-title":"Arch Dermatol"},{"key":"1930_CR3","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1111\/j.1365-4632.2004.01973.x","volume":"43","author":"E Dervis","year":"2004","unstructured":"Dervis E, Acbay O, Barut G, Karaoglu A, Ersoy L: Association of vitiligo, morphea, and Hashimoto's thyroiditis. Int J Dermatol. 2004, 43: 236-237. 10.1111\/j.1365-4632.2004.01973.x.","journal-title":"Int J Dermatol"},{"key":"1930_CR4","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/j.1468-3083.2005.01336.x","volume":"20","author":"C Bonifati","year":"2006","unstructured":"Bonifati C, Impara G, Morrone A, Pietrangeli A, Carducci M: Simultaneous occurrence of linear scleroderma and homolateral segmental vit\u00edligo. J Eur Acad Dermatol Venereol. 2006, 20: 63-65. 10.1111\/j.1468-3083.2005.01336.x.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1930_CR5","first-page":"741","volume":"7","author":"SH Neucks","year":"1980","unstructured":"Neucks SH, Moore TL, Lichtenstein JR, Baldassare AR, Weiss TD, Zuckner J: Localized scleroderma and idiopathic thrombocytopenia. J Rheumatol. 1980, 7: 741-744.","journal-title":"J Rheumatol"},{"key":"1930_CR6","first-page":"88","volume":"18","author":"P Rond\u00f3n","year":"2001","unstructured":"Rond\u00f3n P, Aguilar A, Gallego M: Thrombopenia associated to localized scleroderma. An Med Interna. 2001, 18: 88-89.","journal-title":"An Med Interna"},{"key":"1930_CR7","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1111\/j.1365-2133.1989.tb01350.x","volume":"120","author":"CI Harrington","year":"1989","unstructured":"Harrington CI, Dunsmore IR: An investigation into the incidence of auto-immune disorders in patients with localized morphoea. Br J Dermatol. 1989, 120: 645-648. 10.1111\/j.1365-2133.1989.tb01350.x.","journal-title":"Br J Dermatol"},{"key":"1930_CR8","doi-asserted-by":"publisher","first-page":"336","DOI":"10.2165\/11310800-000000000-00000","volume":"10","author":"S Soylu","year":"2009","unstructured":"Soylu S, G\u00fcl U, G\u00f6n\u00fcl M, Kili\u00e7 A, Cakmak SK, Demiriz M: An uncommon presentation of the co-existence of morphea and vitiligo in a patient with chronic hepatitis B virus infection: is there a possible association with autoimmunity?. Am J Clin Dermatol. 2009, 10: 336-338. 10.2165\/11310800-000000000-00000.","journal-title":"Am J Clin Dermatol"},{"key":"1930_CR9","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1093\/rheumatology\/keh487","volume":"44","author":"K Takehara","year":"2005","unstructured":"Takehara K, Sato S: Localized scleroderma is an autoimmune disorder. Rheumatology (Oxford). 2005, 44: 274-279. 10.1093\/rheumatology\/keh487.","journal-title":"Rheumatology (Oxford)"},{"issue":"5","key":"1930_CR10","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1111\/j.1365-2133.2010.09633.x","volume":"162","author":"E Antiga","year":"2010","unstructured":"Antiga E, Quaglino P, Bellandi S, Volpi W, Del Bianco E, Comessatti A, et al.: Regulatory T cells in the skin lesions and blood of patients with systemic sclerosis and morphoea. Br J Dermatol. 2010, 162 (5): 1056-1063. 10.1111\/j.1365-2133.2010.09633.x.","journal-title":"Br J Dermatol"},{"issue":"6","key":"1930_CR11","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.autrev.2005.01.007","volume":"4","author":"RY Lan","year":"2005","unstructured":"Lan RY, Ansari AA, Lian ZX, Gershwin ME: Regulatory T cells: development, function and role in autoimmunity. Autoimmun Rev. 2005, 4 (6): 351-363. 10.1016\/j.autrev.2005.01.007.","journal-title":"Autoimmun Rev"},{"key":"1930_CR12","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1111\/j.1365-4362.1992.tb04256.x","volume":"31","author":"I Shelkovitz-Shiloh","year":"1992","unstructured":"Shelkovitz-Shiloh I, Ehrenfeld M, Schewach-Millet M, Feinstein A: Coexistence of familial systemic lupus erythematosus and localized scleroderma. Int J Dermatol. 1992, 31: 819-820.","journal-title":"Int J Dermatol"},{"key":"1930_CR13","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1046\/j.1525-1470.2000.01820.x","volume":"17","author":"M Majeed","year":"2000","unstructured":"Majeed M, Al-Mayouf SM, Al-Sabban E, Bahabri S: Coexistent linear scleroderma and juvenile systemic lupus erythematosus. Pediatr Dermatol. 2000, 17: 456-459. 10.1046\/j.1525-1470.2000.01820.x.","journal-title":"Pediatr Dermatol"},{"key":"1930_CR14","first-page":"446","volume":"14","author":"JA Hern\u00e1ndez-Beriain","year":"1996","unstructured":"Hern\u00e1ndez-Beriain JA, Espinel ML, San Rom\u00e1n A, Segura-Garc\u00eda C: Morphea and rheumatoid arthritis. Clin Exp Rheumatol. 1996, 14: 446-447.","journal-title":"Clin Exp Rheumatol"},{"key":"1930_CR15","doi-asserted-by":"publisher","first-page":"S215","DOI":"10.1067\/mjd.2001.103640","volume":"45","author":"A Morita","year":"2001","unstructured":"Morita A, Tsuji T: Necrotizing vasculitis in a patient with generalized morphea. Am Acad Dermatol. 2001, 45: S215-S217. 10.1067\/mjd.2001.103640.","journal-title":"Am Acad Dermatol"},{"key":"1930_CR16","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1007\/s11926-004-0020-5","volume":"6","author":"F Zulian","year":"2004","unstructured":"Zulian F: Systemic manifestations in localized scleroderma. Curr Rheumatol Rep. 2004, 6: 417-424. 10.1007\/s11926-004-0020-5.","journal-title":"Curr Rheumatol Rep"},{"key":"1930_CR17","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/S0022-510X(98)00267-6","volume":"163","author":"N Kanzato","year":"1999","unstructured":"Kanzato N, Matsuzaki T, Komine Y, Saito M, Saito A, Yoshio T, Suehara M: Localized scleroderma associated with progressing ischemic stroke. J Neurol Sci. 1999, 163: 86-89. 10.1016\/S0022-510X(98)00267-6.","journal-title":"J Neurol Sci"},{"key":"1930_CR18","volume-title":"Clin Rev Allergy Immunol","author":"JM Anaya","year":"2012","unstructured":"Anaya JM, Castiblanco J, Rojas-Villarraga A, Pineda-Tamayo R, Levy RA, G\u00f3mez-Puerta J, Dias C, Mantilla RD, Gallo JE, Cervera R, Shoenfeld Y, Arcos-Burgos M: The Multiple Autoimmune Syndromes. A Clue for the Autoimmune Tautology. Clin Rev Allergy Immunol. 2012, [Epub ahead of print]"}],"container-title":["BMC Research Notes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-0500-5-689.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1756-0500-5-689\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-0500-5-689.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T22:01:43Z","timestamp":1548108103000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcresnotes.biomedcentral.com\/articles\/10.1186\/1756-0500-5-689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["1930"],"URL":"https:\/\/doi.org\/10.1186\/1756-0500-5-689","relation":{},"ISSN":["1756-0500"],"issn-type":[{"value":"1756-0500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]},"article-number":"689"}}