{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:15:01Z","timestamp":1761059701070},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2014,12]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The levonorgestrel intrauterine system, Mirena\u00ae, is widely used for contraception and the treatment of idiopathic menorrhagia. Here, we reported one case of acute urticaria following Mirena\u00ae implantation to increase the awareness of possible adverse side effects associated with Mirena\u00ae.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n The case presented is a 27-year-old Chinese woman who received Mirena\u00ae implantation for her adenomyosis and menorrhagia. The operation was successful and the patient did not experience any discomfort during the operation. However, she developed acute urticaria on her entire body accompanied with pruritic, slight left lower quadrant pain, and slight dizziness two hours after the operation. The patient was recommended to have the Mirena\u00ae removed immediately, and she took 10\u00a0mg oral methylprednisolone and 5\u00a0mg desloratadine tablet daily for five days. Her urticaria resolved and did not recur.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The patient\u2019s acute urticaria seems to have been associated with the Mirena\u00ae levonorgestrel intrauterine system implantation, since she had no history of allergic reactions to materials used during the operation such as plastic, metal, alcohol, medications, and povidone-iodine.<\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/1756-0500-7-209","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T09:11:05Z","timestamp":1396516265000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Acute urticaria as a side effect of the Mirena\u00ae (levonorgestrel-releasing intrauterine system): a case report"],"prefix":"10.1186","volume":"7","author":[{"given":"Xiangjuan","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueqing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"2730_CR1","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.ejogrb.2005.10.029","volume":"125","author":"R Varma","year":"2006","unstructured":"Varma R, Sinha D, Gupta JK: Non-contraceptive uses of levonorgestrel-releasing hormone system (LNG-IUS)\u2014a systematic enquiry and overview. Eur J Obstet Gynecol Reprod Biol. 2006, 125: 9-28. 10.1016\/j.ejogrb.2005.10.029.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2730_CR2","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0010-7824(02)00329-3","volume":"66","author":"JB Dubuissona","year":"2002","unstructured":"Dubuissona JB, Mugnierb E, the Mirena\u00ae Study Groupa: Acceptability of the levonorgestrel-releasing intrauterine system after discontinuation of previous contraception: results of a French clinical study in women aged 35 to 45 years. Contraception. 2002, 66: 121-128. 10.1016\/S0010-7824(02)00329-3.","journal-title":"Contraception"},{"key":"2730_CR3","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1097\/01.AOG.0000143824.16435.91","volume":"104","author":"I Rauramo","year":"2004","unstructured":"Rauramo I, Elo I, Istre O: Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resection. Obstet Gynecol. 2004, 104: 1314-1321. 10.1097\/01.AOG.0000143824.16435.91.","journal-title":"Obstet Gynecol"},{"key":"2730_CR4","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1080\/13625180500178767","volume":"11","author":"K Karri","year":"2006","unstructured":"Karri K, Mowbray D, Adams S, Rendall JRS: Severe seborrhoeic dermatitis: Side-effect of the Mirena intra-uterine system. Eur J Contracept Reprod Health Care. 2006, 11: 53-54.","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"2730_CR5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1080\/0144361021000082665","volume":"23","author":"A Pereira","year":"2003","unstructured":"Pereira A, Coker A: Hypersensitivity to mirena-a rare complication. J Obstet Gynaecol. 2003, 23: 81-92.","journal-title":"J Obstet Gynaecol"}],"container-title":["BMC Research Notes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-0500-7-209.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T00:29:48Z","timestamp":1630542588000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcresnotes.biomedcentral.com\/articles\/10.1186\/1756-0500-7-209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,3]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["2730"],"URL":"https:\/\/doi.org\/10.1186\/1756-0500-7-209","relation":{},"ISSN":["1756-0500"],"issn-type":[{"value":"1756-0500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,3]]},"assertion":[{"value":"25 August 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"209"}}