{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:38:10Z","timestamp":1792701490569,"version":"4.5.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Res Notes"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Gastrointestinal stromal tumor (GIST) is a rare tumor comprising 0.1-0.3% of all gastrointestinal (GI) malignancies. Stomach followed by small intestine is the most common sites of involvement, implicated in 95% of the cases. We present a case of GIST complicating a colonic interposition. To the best of the author's knowledge, this is the first reported case of GIST complicating a colonic interposition.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A 47 year old African American male presented to the emergency department with intermittent, severe chest pain. Past medical history was significant for alkali (NaOH) ingestion during 1980 for which esophageal resection and a colonic pull-through was performed. A CXR revealed a widened mediastinum and CT scan chest revealed showed a large (11.4 \u00d7 8.3 \u00d7 12.1 cm) vascular mediastinal mass. At endoscopy, a large, ulcerated, cratered and friable mass was found at 29cm extending to 36cm at which point the lower anastomosis of the colonic pull through was present. Multiple endoscopic biopsies were obtained which showed that the tumor was immunoreactive with CD117, CD34 and DOG1 while markers of carcinoma, melanoma and lymphoma were negative. In light of the pathology report, the immunohistochemistry and the CT scans, the tumor was classified as a stage 4 GIST of colonic interposition.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>GIST can complicate unusual locations such as colonic interposition and should be kept in the differential diagnosis of such unusual presentations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1756-0500-7-604","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T22:13:28Z","timestamp":1409868808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Gastro-intestinal stromal tumor (GIST) complicating a colonic interposition: a novel case report"],"prefix":"10.1186","volume":"7","author":[{"given":"Maaz B","family":"Badshah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haris","family":"Riaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A","family":"Korsten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atiya","family":"Dhala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeun-Hee A","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Abadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mashood B","family":"Badshah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,9,4]]},"reference":[{"issue":"2","key":"3134_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1053\/j.semdp.2006.09.001","volume":"23","author":"M Miettinen","year":"2006","unstructured":"Miettinen M, Lasota J: Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol. 2006, 23 (2): 70-83. 10.1053\/j.semdp.2006.09.001.","journal-title":"Semin Diagn Pathol"},{"issue":"2","key":"3134_CR2","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1148\/rg.232025146","volume":"23","author":"AD Levy","year":"2003","unstructured":"Levy AD, Remotti HE, Thompson WM, Sobin LH, Miettinen M: Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics. 2003, 23 (2): 283-304. 10.1148\/rg.232025146. 456; quiz 532","journal-title":"Radiographics"},{"issue":"3","key":"3134_CR3","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.jchir.2009.06.008","volume":"146","author":"M Chirica","year":"2009","unstructured":"Chirica M, De Chaisemartin C, Munoz-Bongrand N, Halimi B, Celerier M, Cattan P, Sarfati E: [Colonic interposition for esophageal replacement after caustic ingestion]. J Chir (Paris). 2009, 146 (3): 240-249. 10.1016\/j.jchir.2009.06.008. Epub 2009 Jul 28","journal-title":"J Chir (Paris)"},{"issue":"19","key":"3134_CR4","doi-asserted-by":"publisher","first-page":"2846","DOI":"10.3748\/wjg.v10.i19.2846","volume":"10","author":"Y Han","year":"2004","unstructured":"Han Y, Cheng QS, Li XF, Wang XP: Surgical management of esophageal strictures after caustic burns: A 30 years of experience. World J Gastroenterol. 2004, 10 (19): 2846-2849.","journal-title":"World J Gastroenterol"},{"issue":"3","key":"3134_CR5","doi-asserted-by":"publisher","first-page":"392","DOI":"10.3748\/wjg.v16.i3.392","volume":"16","author":"H Bando","year":"2010","unstructured":"Bando H, Ikematsu H, Fu KI, Oono Y, Kojima T, Minashi K, Yano T, Matsuda T, Saito Y, Kaneko K, Ohtsu A: A laterally-spreading tumor in a colonic interposition treated by endoscopic submucosal dissection. World J Gastroenterol. 2010, 16 (3): 392-394. 10.3748\/wjg.v16.i3.392.","journal-title":"World J Gastroenterol"},{"issue":"1","key":"3134_CR6","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1477-7819-10-66","volume":"10","author":"L Zhou","year":"2012","unstructured":"Zhou L, Liu C, Bai JG, Wei JC, Qu K, Tian F, Tai MH, Wang RT, Meng FD: A rare giant gastrointestinal stromal tumor (GIST) of the stomach traversing the upper abdomen: a case report and literature review. World J Surg Oncol. 2012, 10 (1): 66-10.1186\/1477-7819-10-66.","journal-title":"World J Surg Oncol"},{"issue":"10","key":"3134_CR7","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1097\/00000478-200010000-00003","volume":"24","author":"M Miettinen","year":"2000","unstructured":"Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J: Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. 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