{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T02:14:38Z","timestamp":1780625678553,"version":"3.54.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,1,11]],"date-time":"2010-01-11T00:00:00Z","timestamp":1263168000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hematol Oncol"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1186\/1756-8722-3-2","type":"journal-article","created":{"date-parts":[[2010,1,13]],"date-time":"2010-01-13T11:41:34Z","timestamp":1263382894000},"source":"Crossref","is-referenced-by-count":35,"title":["Leser-Tr\u00e9lat syndrome in patients affected by six multiple metachronous primitive cancers"],"prefix":"10.1186","volume":"3","author":[{"given":"Giovanni","family":"Ponti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Luppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena","family":"Losi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Giannetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Seidenari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,1,11]]},"reference":[{"key":"86_CR1","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/S1470-2045(08)70126-8","volume":"9","author":"IM Winship","year":"2008","unstructured":"Winship IM, Dubbing TE: Lesson from the skin-cutaneous features of familial cancer. Lancet Oncol. 2008, 9: 462-472. 10.1016\/S1470-2045(08)70126-8.","journal-title":"Lancet Oncol"},{"key":"86_CR2","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1016\/S1470-2045(05)70465-4","volume":"6","author":"G Ponti","year":"2005","unstructured":"Ponti G, Ponz de Leon M: Muir-Torre Syndrome. Lancet Oncol. 2005, 6: 980-987. 10.1016\/S1470-2045(05)70465-4.","journal-title":"Lancet Oncol"},{"key":"86_CR3","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1136\/jmg.2003.017806","volume":"42","author":"AJ Bauer","year":"2005","unstructured":"Bauer AJ, Stratakis CA: The lentiginoses: cutaneous markers of systemic disease and a window to new aspects of tumourigenesis. J Med Genet. 2005, 42: 801-810. 10.1136\/jmg.2003.017806.","journal-title":"J Med Genet"},{"issue":"7","key":"86_CR4","first-page":"498","volume":"38","author":"A Lee","year":"2009","unstructured":"Lee A: Skin manifestation of systemic disease. Aust Fam Physician. 2009, 38 (7): 498-505.","journal-title":"Aust Fam Physician"},{"key":"86_CR5","first-page":"2035","volume":"51","author":"E Leser","year":"1901","unstructured":"Leser E: Ueber ein die Krebskrankheit beim Menschen haufig begleitendes, noch wenig gekanntes Symptom. Munchener Med Wochenschr. 1901, 51: 2035-2036.","journal-title":"Munchener Med Wochenschr"},{"key":"86_CR6","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1055\/s-0029-1203939","volume":"26","author":"EV Hollander","year":"1900","unstructured":"Hollander EV: Beitrage zur Fruhdiagnose des Darmcarcinomas (Hereditatsverhaltnisse und Hautveranderungen). Dtsch Med Wochenschr. 1900, 26: 483-485. 10.1055\/s-0029-1203939.","journal-title":"Dtsch Med Wochenschr"},{"issue":"6","key":"86_CR7","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/0190-9622(92)70139-7","volume":"26","author":"B Lindel\u00f6f","year":"1992","unstructured":"Lindel\u00f6f B, Sigurgeirsson B, Melander S: Seborrheic keratoses and cancer. J Am Acad Dermatol. 1992, 26 (6): 947-950. 10.1016\/0190-9622(92)70139-7.","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"86_CR8","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1111\/j.1365-2230.1988.tb01964.x","volume":"13","author":"LE Schwengle","year":"1988","unstructured":"Schwengle LE, Rampen FH, Wobbes T: Seborrhoeic keratoses and internal malignancies. A case control study. Clin Exp Dermatol. 1988, 13 (3): 177-179. 10.1111\/j.1365-2230.1988.tb01964.x.","journal-title":"Clin Exp Dermatol"},{"issue":"2","key":"86_CR9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.2340\/0001555571166169","volume":"71","author":"JJ Grob","year":"1991","unstructured":"Grob JJ, Rava MC, Gouvernet J: The relation between seborrheic keratoses and malignant solid tumours. A case-control study. Acta Derm Venereol. 1991, 71 (2): 166-169.","journal-title":"Acta Derm Venereol"},{"issue":"25","key":"86_CR10","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1056\/NEJM198712173172506","volume":"317","author":"DL Ellis","year":"1987","unstructured":"Ellis DL, Kafka SP, Chow JC: Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trelat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes. N Engl J Med. 1987, 317 (25): 1582-1587. 10.1056\/NEJM198712173172506.","journal-title":"N Engl J Med"},{"key":"86_CR11","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1067\/mjd.2000.104967","volume":"43","author":"MR Heaphy Jr","year":"2000","unstructured":"Heaphy MR, Millns JL, Schroeter AL: The sign of Leser-Trelat in a case of adenocarcinoma of the lung. J Am Acad Dermatol. 2000, 43: 386-390. 10.1016\/S0190-9622(00)70301-X.","journal-title":"J Am Acad Dermatol"},{"key":"86_CR12","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/0190-9622(92)70139-7","volume":"26","author":"B Lindel\u00f6f","year":"1992","unstructured":"Lindel\u00f6f B, Sigurgeirsson B, Melander S: Seborrheic keratoses and cancer. J Am Acad Dermatol. 1992, 26: 947-950. 10.1016\/0190-9622(92)70139-7.","journal-title":"J Am Acad Dermatol"}],"container-title":["Journal of Hematology &amp; Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-8722-3-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1756-8722-3-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-8722-3-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T19:23:51Z","timestamp":1711135431000},"score":1,"resource":{"primary":{"URL":"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/1756-8722-3-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,11]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["86"],"URL":"https:\/\/doi.org\/10.1186\/1756-8722-3-2","relation":{},"ISSN":["1756-8722"],"issn-type":[{"value":"1756-8722","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,11]]},"article-number":"2"}}