{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:42:29Z","timestamp":1792024949753,"version":"4.4.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,10,12]],"date-time":"2011-10-12T00:00:00Z","timestamp":1318377600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Exp Clin Cancer Res"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1186\/1756-9966-30-96","type":"journal-article","created":{"date-parts":[[2011,10,13]],"date-time":"2011-10-13T02:14:32Z","timestamp":1318472072000},"source":"Crossref","is-referenced-by-count":67,"title":["HGF\/c-Met related activation of \u03b2-catenin in hepatoblastoma"],"prefix":"10.1186","volume":"30","author":[{"given":"Rachel","family":"Purcell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Childs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Maibach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Miles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,10,12]]},"reference":[{"key":"513_CR1","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/S1470-2045(00)00018-8","volume":"1","author":"G Perilongo","year":"2000","unstructured":"Perilongo G, et al: SIOPEL trials using preoperative chemotherapy in hepatoblastoma. [Review] [28 refs]. Lancet Oncology. 2000, 1: 94-100. 10.1016\/S1470-2045(00)00018-8.","journal-title":"Lancet Oncology"},{"issue":"13","key":"513_CR2","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1016\/j.ejca.2006.05.011","volume":"42","author":"CA Stiller","year":"2006","unstructured":"Stiller CA, Pritchard J, Steliarova-Foucher E: Liver cancer in European children: incidence and survival, 1978-1997. Report from the Automated Childhood Cancer Information System project. European Journal of Cancer. 2006, 42 (13): 2115-23. 10.1016\/j.ejca.2006.05.011.","journal-title":"European Journal of Cancer"},{"issue":"1","key":"513_CR3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/ejhg.2009.106","volume":"18","author":"R Weksberg","year":"2009","unstructured":"Weksberg R, Shuman C, Beckwith JB: Beckwith-Wiedemann syndrome. Eur J Hum Genet. 2009, 18 (1): 8-14.","journal-title":"Eur J Hum Genet"},{"issue":"2","key":"513_CR4","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jpeds.2005.04.019","volume":"147","author":"BA Hirschman","year":"2005","unstructured":"Hirschman BA, Pollock BH, Tomlinson GE: The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds. Journal of Pediatrics. 2005, 147 (2): 263-6. 10.1016\/j.jpeds.2005.04.019.","journal-title":"Journal of Pediatrics"},{"issue":"11","key":"513_CR5","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1016\/j.ejca.2005.02.035","volume":"41","author":"A Zimmermann","year":"2005","unstructured":"Zimmermann A: The emerging family of hepatoblastoma tumours: from ontogenesis to oncogenesis. European Journal of Cancer. 2005, 41 (11): 1503-14. 10.1016\/j.ejca.2005.02.035.","journal-title":"European Journal of Cancer"},{"issue":"5","key":"513_CR6","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1002\/mpo.10174","volume":"39","author":"A Zimmermann","year":"2002","unstructured":"Zimmermann A: Pediatric liver tumors and hepatic ontogenesis: common and distinctive pathways. Med Pediatr Oncol. 2002, 39 (5): 492-503. 10.1002\/mpo.10174.","journal-title":"Med Pediatr Oncol"},{"issue":"11","key":"513_CR7","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1038\/sj.bjc.6604754","volume":"99","author":"S Honda","year":"2008","unstructured":"Honda S, et al: Loss of imprinting of IGF2 correlates with hypermethylation of the H19 differentially methylated region in hepatoblastoma. British Journal of Cancer. 2008, 99 (11): 1891-9. 10.1038\/sj.bjc.6604754.","journal-title":"British Journal of Cancer"},{"issue":"9","key":"513_CR8","first-page":"1836","volume":"55","author":"S Rainier","year":"1995","unstructured":"Rainier S, Dobry CJ, Feinberg AP: Loss of imprinting in hepatoblastoma. Cancer Research. 1995, 55 (9): 1836-8.","journal-title":"Cancer Research"},{"issue":"6","key":"513_CR9","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.humpath.2008.07.022","volume":"40","author":"D Lopez-Terrada","year":"2009","unstructured":"Lopez-Terrada D, et al: Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors. Hum Pathol. 2009, 40 (6): 783-94. 10.1016\/j.humpath.2008.07.022.","journal-title":"Hum Pathol"},{"issue":"6","key":"513_CR10","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.humpath.2008.10.022","volume":"40","author":"AM Adesina","year":"2009","unstructured":"Adesina AM, et al: Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways. Hum Pathol. 2009, 40 (6): 843-53. 10.1016\/j.humpath.2008.10.022.","journal-title":"Hum Pathol"},{"issue":"1","key":"513_CR11","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S0304-3835(99)00433-4","volume":"152","author":"YM Jeng","year":"2000","unstructured":"Jeng YM, et al: Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma. Cancer Lett. 2000, 152 (1): 45-51. 10.1016\/S0304-3835(99)00433-4.","journal-title":"Cancer Lett"},{"issue":"2","key":"513_CR12","first-page":"269","volume":"59","author":"A Koch","year":"1999","unstructured":"Koch A, et al: Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res. 1999, 59 (2): 269-73.","journal-title":"Cancer Res"},{"issue":"4","key":"513_CR13","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1038\/sj.onc.1203356","volume":"19","author":"Y Wei","year":"2000","unstructured":"Wei Y, et al: Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas. Oncogene. 2000, 19 (4): 498-504. 10.1038\/sj.onc.1203356.","journal-title":"Oncogene"},{"issue":"3","key":"513_CR14","first-page":"551","volume":"15","author":"H Yamaoka","year":"2006","unstructured":"Yamaoka H, et al: Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors. Oncology Reports. 2006, 15 (3): 551-6.","journal-title":"Oncology Reports"},{"issue":"31","key":"513_CR15","doi-asserted-by":"publisher","first-page":"4863","DOI":"10.1038\/sj.onc.1205591","volume":"21","author":"K Taniguchi","year":"2002","unstructured":"Taniguchi K, et al: Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene. 2002, 21 (31): 4863-71. 10.1038\/sj.onc.1205591.","journal-title":"Oncogene"},{"issue":"3","key":"513_CR16","first-page":"551","volume":"15","author":"H Yamaoka","year":"2006","unstructured":"Yamaoka H, et al: Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors. Oncol Rep. 2006, 15 (3): 551-6.","journal-title":"Oncol Rep"},{"issue":"4","key":"513_CR17","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/(SICI)1098-2264(199908)25:4<399::AID-GCC14>3.0.CO;2-X","volume":"25","author":"H Blaker","year":"1999","unstructured":"Blaker H, et al: Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma. Genes Chromosomes Cancer. 1999, 25 (4): 399-402. 10.1002\/(SICI)1098-2264(199908)25:4<399::AID-GCC14>3.0.CO;2-X.","journal-title":"Genes Chromosomes Cancer"},{"issue":"4","key":"513_CR18","first-page":"901","volume":"7","author":"H Takayasu","year":"2001","unstructured":"Takayasu H, et al: Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma. Clin Cancer Res. 2001, 7 (4): 901-8.","journal-title":"Clin Cancer Res"},{"issue":"7","key":"513_CR19","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1007\/s003830000576","volume":"17","author":"Y Udatsu","year":"2001","unstructured":"Udatsu Y, et al: High frequency of beta-catenin mutations in hepatoblastoma. Pediatr Surg Int. 2001, 17 (7): 508-12. 10.1007\/s003830000576.","journal-title":"Pediatr Surg Int"},{"issue":"57","key":"513_CR20","doi-asserted-by":"publisher","first-page":"7482","DOI":"10.1038\/sj.onc.1210055","volume":"25","author":"D Kimelman","year":"2006","unstructured":"Kimelman D, Xu W: beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene. 2006, 25 (57): 7482-91. 10.1038\/sj.onc.1210055.","journal-title":"Oncogene"},{"issue":"5663","key":"513_CR21","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1126\/science.1094291","volume":"303","author":"WJ Nelson","year":"2004","unstructured":"Nelson WJ, Nusse R: Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 2004, 303 (5663): 1483-7. 10.1126\/science.1094291.","journal-title":"Science"},{"issue":"6","key":"513_CR22","doi-asserted-by":"publisher","first-page":"G1578","DOI":"10.1152\/ajpgi.00359.2006","volume":"292","author":"U Apte","year":"2007","unstructured":"Apte U, et al: beta-Catenin is critical for early postnatal liver growth. Am J Physiol Gastrointest Liver Physiol. 2007, 292 (6): G1578-85. 10.1152\/ajpgi.00359.2006.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"2","key":"513_CR23","doi-asserted-by":"publisher","first-page":"92","DOI":"10.4161\/org.4.2.5855","volume":"4","author":"K Nejak-Bowen","year":"2008","unstructured":"Nejak-Bowen K, Monga SP: Wnt\/beta-catenin signaling in hepatic organogenesis. Organogenesis. 2008, 4 (2): 92-9. 10.4161\/org.4.2.5855.","journal-title":"Organogenesis"},{"key":"513_CR24","volume-title":"Lab Invest","author":"XZ Shang","year":"2004","unstructured":"Shang XZ, et al: Stabilized beta-catenin promotes hepatocyte proliferation and inhibits TNFalpha-induced apoptosis. Lab Invest. 2004"},{"issue":"1","key":"513_CR25","first-page":"121","volume":"11","author":"T Inukai","year":"2004","unstructured":"Inukai T, et al: Nuclear accumulation of beta-catenin without an additional somatic mutation in coding region of the APC gene in hepatoblastoma from a familial adenomatous polyposis patient. [Review] [40 refs]. Oncology Reports. 2004, 11 (1): 121-6.","journal-title":"Oncology Reports"},{"issue":"4","key":"513_CR26","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s10024-005-0028-5","volume":"8","author":"S Ranganathan","year":"2005","unstructured":"Ranganathan S, Tan X, Monga SP: beta-Catenin and met deregulation in childhood Hepatoblastomas. Pediatric & Developmental Pathology. 2005, 8 (4): 435-47. 10.1007\/s10024-005-0028-5.","journal-title":"Pediatric & Developmental Pathology"},{"issue":"7","key":"513_CR27","first-page":"2064","volume":"62","author":"SP Monga","year":"2002","unstructured":"Monga SP, et al: Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res. 2002, 62 (7): 2064-71.","journal-title":"Cancer Res"},{"issue":"18","key":"513_CR28","doi-asserted-by":"publisher","first-page":"3620","DOI":"10.1016\/j.yexcr.2006.08.003","volume":"312","author":"G Zeng","year":"2006","unstructured":"Zeng G, et al: Tyrosine residues 654 and 670 in beta-catenin are crucial in regulation of Met-beta-catenin interactions. Exp Cell Res. 2006, 312 (18): 3620-30. 10.1016\/j.yexcr.2006.08.003.","journal-title":"Exp Cell Res"},{"issue":"12","key":"513_CR29","doi-asserted-by":"publisher","first-page":"3657","DOI":"10.1158\/1078-0432.CCR-06-0818","volume":"12","author":"B Peruzzi","year":"2006","unstructured":"Peruzzi B, Bottaro DP: Targeting the c-Met signaling pathway in cancer. Clin Cancer Res. 2006, 12 (12): 3657-60. 10.1158\/1078-0432.CCR-06-0818.","journal-title":"Clin Cancer Res"},{"issue":"3","key":"513_CR30","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1055\/s-2008-1071139","volume":"8","author":"D von Schweinitz","year":"1998","unstructured":"von Schweinitz D, et al: The occurrence of liver growth factor in hepatoblastoma. Eur J Pediatr Surg. 1998, 8 (3): 133-6. 10.1055\/s-2008-1071139.","journal-title":"Eur J Pediatr Surg"},{"issue":"2","key":"513_CR31","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/(SICI)1097-0215(20000115)85:2<151::AID-IJC1>3.0.CO;2-6","volume":"85","author":"D von Schweinitz","year":"2000","unstructured":"von Schweinitz D, et al: Hepatocyte growth-factor-scatter factor can stimulate post-operative tumor-cell proliferation in childhood hepatoblastoma. Int J Cancer. 2000, 85 (2): 151-9.","journal-title":"Int J Cancer"},{"issue":"17","key":"513_CR32","doi-asserted-by":"publisher","first-page":"5857","DOI":"10.1128\/MCB.21.17.5857-5868.2001","volume":"21","author":"A Danilkovitch-Miagkova","year":"2001","unstructured":"Danilkovitch-Miagkova A, et al: Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway. Mol Cell Biol. 2001, 21 (17): 5857-68. 10.1128\/MCB.21.17.5857-5868.2001.","journal-title":"Mol Cell Biol"},{"issue":"17","key":"513_CR33","doi-asserted-by":"publisher","first-page":"1662","DOI":"10.1056\/NEJMoa0810613","volume":"361","author":"G Perilongo","year":"2009","unstructured":"Perilongo G, et al: Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma. N Engl J Med. 2009, 361 (17): 1662-70. 10.1056\/NEJMoa0810613.","journal-title":"N Engl J Med"},{"issue":"1B","key":"513_CR34","first-page":"561","volume":"17","author":"J Zsiros","year":"2010","unstructured":"Zsiros J, et al: Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study. J Clin Oncol. 2010, 17 (1B): 561-7.","journal-title":"J Clin Oncol"},{"issue":"5","key":"513_CR35","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1002\/mpo.10180","volume":"39","author":"MA Buendia","year":"2002","unstructured":"Buendia MA: Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects. [Review] [69 refs]. Medical & Pediatric Oncology. 2002, 39 (5): 530-5. 10.1002\/mpo.10180.","journal-title":"Medical & Pediatric Oncology"},{"issue":"1","key":"513_CR36","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/modpathol.3800977","volume":"21","author":"MC Curia","year":"2008","unstructured":"Curia MC, et al: Sporadic childhood hepatoblastomas show activation of beta-catenin, mismatch repair defects and p53 mutations. Modern Pathology. 2008, 21 (1): 7-14. 10.1038\/modpathol.3800977.","journal-title":"Modern Pathology"},{"issue":"4","key":"513_CR37","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH804>3.0.CO;2-R","volume":"193","author":"WS Park","year":"2001","unstructured":"Park WS, et al: Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma. J Pathol. 2001, 193 (4): 483-90. 10.1002\/1096-9896(2000)9999:9999<::AID-PATH804>3.0.CO;2-R.","journal-title":"J Pathol"},{"issue":"5","key":"513_CR38","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1002\/mpo.10180","volume":"39","author":"MA Buendia","year":"2002","unstructured":"Buendia MA: Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects. Med Pediatr Oncol. 2002, 39 (5): 530-5. 10.1002\/mpo.10180.","journal-title":"Med Pediatr Oncol"},{"issue":"1","key":"513_CR39","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S1359-6101(01)00029-6","volume":"13","author":"G Maulik","year":"2002","unstructured":"Maulik G, et al: Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev. 2002, 13 (1): 41-59. 10.1016\/S1359-6101(01)00029-6.","journal-title":"Cytokine Growth Factor Rev"},{"issue":"3","key":"513_CR40","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1002\/hep.22695","volume":"49","author":"B Cieply","year":"2009","unstructured":"Cieply B, et al: Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene. Hepatology. 2009, 49 (3): 821-31. 10.1002\/hep.22695.","journal-title":"Hepatology"},{"issue":"12","key":"513_CR41","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1002\/(SICI)1521-1878(199912)22:1<1021::AID-BIES6>3.0.CO;2-P","volume":"21","author":"PJ Morin","year":"1999","unstructured":"Morin PJ: beta-catenin signaling and cancer. Bioessays. 1999, 21 (12): 1021-30. 10.1002\/(SICI)1521-1878(199912)22:1<1021::AID-BIES6>3.0.CO;2-P.","journal-title":"Bioessays"},{"issue":"10","key":"513_CR42","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1038\/modpathol.3800181","volume":"17","author":"B Bellei","year":"2004","unstructured":"Bellei B, et al: Frequent beta-catenin overexpression without exon 3 mutation in cutaneous lymphomas. Mod Pathol. 2004, 17 (10): 1275-81. 10.1038\/modpathol.3800181.","journal-title":"Mod Pathol"},{"issue":"18","key":"513_CR43","first-page":"6656","volume":"61","author":"M Fujimori","year":"2001","unstructured":"Fujimori M, et al: Accumulation of beta-catenin protein and mutations in exon 3 of beta-catenin gene in gastrointestinal carcinoid tumor. Cancer Res. 2001, 61 (18): 6656-9.","journal-title":"Cancer Res"},{"issue":"2","key":"513_CR44","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/S0002-9440(10)65278-9","volume":"154","author":"DL Rimm","year":"1999","unstructured":"Rimm DL, et al: Frequent nuclear\/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am J Pathol. 1999, 154 (2): 325-9. 10.1016\/S0002-9440(10)65278-9.","journal-title":"Am J Pathol"},{"issue":"5","key":"513_CR45","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1002\/(SICI)1097-0215(19990827)82:5<625::AID-IJC1>3.0.CO;2-2","volume":"82","author":"K Wright","year":"1999","unstructured":"Wright K, et al: beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours. Int J Cancer. 1999, 82 (5): 625-9. 10.1002\/(SICI)1097-0215(19990827)82:5<625::AID-IJC1>3.0.CO;2-2.","journal-title":"Int J Cancer"},{"issue":"4","key":"513_CR46","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1593\/neo.05607","volume":"8","author":"G Zeng","year":"2006","unstructured":"Zeng G, et al: Aberrant Wnt\/beta-catenin signaling in pancreatic adenocarcinoma. Neoplasia. 2006, 8 (4): 279-89. 10.1593\/neo.05607.","journal-title":"Neoplasia"}],"container-title":["Journal of Experimental &amp; Clinical Cancer Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-9966-30-96.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1756-9966-30-96\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1756-9966-30-96.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T03:26:34Z","timestamp":1548213994000},"score":1,"resource":{"primary":{"URL":"https:\/\/jeccr.biomedcentral.com\/articles\/10.1186\/1756-9966-30-96"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,12]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["513"],"URL":"https:\/\/doi.org\/10.1186\/1756-9966-30-96","relation":{},"ISSN":["1756-9966"],"issn-type":[{"value":"1756-9966","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,12]]},"article-number":"96"}}