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However existing data has been drawn from small non\u2010randomised clinical studies of single interventions that appear to under\u2010represent the adult population suffering from juvenile idiopathic arthritis. To date, no evidence of combined therapies or integrated care for juvenile idiopathic arthritis patients with foot and ankle problems exists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/design<\/jats:title><jats:p>An exploratory phase II non\u2010pharmacological randomised controlled trial where patients including young children, adolescents and adults with juvenile idiopathic arthritis and associated foot\/ankle problems will be randomised to receive integrated podiatric care via a new foot care programme, or to receive standard podiatry care. Sixty patients (30\u00a0in each arm) including children, adolescents and adults diagnosed with juvenile idiopathic arthritis who satisfy the inclusion and exclusion criteria will be recruited from 2 outpatient centres of paediatric and adult rheumatology respectively. Participants will be randomised by process of minimisation using the Minim software package. The primary outcome measure is the foot related impairment measured by the Juvenile Arthritis Disability Index questionnaire's impairment domain at 6 and 12\u00a0months, with secondary outcomes including disease activity score, foot deformity score, active\/limited foot joint counts, spatio\u2010temporal and plantar\u2010pressure gait parameters, health related quality of life and semi\u2010quantitative ultrasonography score for inflammatory foot lesions. The new foot care programme will comprise rapid assessment and investigation, targeted treatment, with detailed outcome assessment and follow\u2010up at minimum intervals of 3\u00a0months. Data will be collected at baseline, 6\u00a0months and 12\u00a0months from baseline. Intention to treat data analysis will be conducted.<\/jats:p><jats:p>A full health economic evaluation will be conducted alongside the trial and will evaluate the cost effectiveness of the intervention. This will consider the cost per improvement in Juvenile Arthritis Disability Index, and cost per quality adjusted life year gained. In addition, a discrete choice experiment will elicit willingness to pay values and a cost benefit analysis will also be undertaken.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration<\/jats:title><jats:p>Trial registration number: UKCRN5045<\/jats:p><\/jats:sec>","DOI":"10.1186\/1757-1146-2-21","type":"journal-article","created":{"date-parts":[[2009,6,30]],"date-time":"2009-06-30T18:22:16Z","timestamp":1246386136000},"source":"Crossref","is-referenced-by-count":6,"title":["Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA"],"prefix":"10.1002","volume":"2","author":[{"given":"Gordon J","family":"Hendry","sequence":"first","affiliation":[{"name":"School of Health and Social Care Glasgow Caledonian University Cowcaddens Road Glasgow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah 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