{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:04:30Z","timestamp":1791266670163,"version":"4.1.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cases Journal"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Q fever is a zoonotic disease caused by coxiella burnetii. The Jarisch-Herxheimer reaction (JHR) is associated with the antibiotic treatment of certain bacterial infections. We report a very rare case of a 36-year-old male with Q fever pneumonia that resulted in recurrent ARDS and presented the JHR during his treatment. The patient was admitted for treatment of community acquired pneumonia. He developed ARDS, was intubated and placed on mechanical ventilation. Doxycycline was empirically added to his antibiotic regiment. The patient presented an acute rise in temperature, tachycardia, tachypnea, hypoxia, hypotension and a temporary deterioration of his chest x-ray. The same 6-hour-long reaction which is known as JHR was presented another 3 times. Cultures were negative but antibodies against coxiella burnetii were positive. This case reminds us that any deterioration of a patient treated in the ICU should not be considered as a new septic episode and time should be allowed for the antibiotic regiments.<\/jats:p>","DOI":"10.1186\/1757-1626-1-360","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T19:13:25Z","timestamp":1227986005000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Recurrent Jarisch-Herxheimer reaction in a patient with Q fever pneumonia: a case report"],"prefix":"10.1186","volume":"1","author":[{"given":"Stavros","family":"Aloizos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Gourgiotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Oikonomou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraskevi","family":"Stakia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,11,29]]},"reference":[{"key":"353_CR1","doi-asserted-by":"crossref","unstructured":"The acute respiratory distress syndrome network. 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Eur Respir J. 2002, 20: 1299-1313. 10.1183\/09031936.02.00401602.","journal-title":"Eur Respir J"},{"key":"353_CR9","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1161\/01.RES.0000059414.10360.F2","volume":"92","author":"KM Ridge","year":"2003","unstructured":"Ridge KM, Olivera WG, Saldias F, Azzam Z, Horowitz S, Rutschman DH, Dumasius V, Factor P, Sznajder JI: Alveolar type 1 cells express the alpha2 Na, K-ATPase, which contributes to lung liquid clearance. Circ Res. 2003, 92: 453-460. 10.1161\/01.RES.0000059414.10360.F2.","journal-title":"Circ Res"}],"container-title":["Cases Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/1757-1626-1-360.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T14:07:36Z","timestamp":1630591656000},"score":1,"resource":{"primary":{"URL":"https:\/\/casesjournal.biomedcentral.com\/articles\/10.1186\/1757-1626-1-360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,29]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["353"],"URL":"https:\/\/doi.org\/10.1186\/1757-1626-1-360","relation":{},"ISSN":["1757-1626"],"issn-type":[{"value":"1757-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,29]]},"assertion":[{"value":"29 October 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"360"}}